CN103736068A - Drug for treating vulvar pruritus - Google Patents
Drug for treating vulvar pruritus Download PDFInfo
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- CN103736068A CN103736068A CN201410026197.6A CN201410026197A CN103736068A CN 103736068 A CN103736068 A CN 103736068A CN 201410026197 A CN201410026197 A CN 201410026197A CN 103736068 A CN103736068 A CN 103736068A
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Abstract
The invention relates to a drug for treating vulvar pruritus. The drug is prepared from the following crude drugs in parts by weight: microsorium buergerianum, millenarian moxa, threeflowered bluebeard herb, impatiens noli-tangere, cassia twig, blumea megacephala, white peony root, coelogyne fimbriata, radix ophiopogonis, ligustrum quihoui, radix angelicae, cixuehong (Chinese character), mulberry leaves, rentouqi (Chinese character), poria cocos, goat-ear elecampane, coix seeds, common elsholtzia herb and ginger. The drug for treating vulvar pruritus disclosed by the invention has the effects of clearing away heat and toxic materials, cooling blood and hemostasis, scattering addiction and relieving swelling, and the vulvar pruritus can be effectively treated.
Description
Technical field
The present invention relates to health check-up section field, relate in particular to a kind of medicament for the treatment of pruritus vulvae.
Background technology
Pruritus vulvae can occur separately, also can be the local symptom of multiple vulvovaginal illness and some systemic disease, as the Symptoms of vulvitis, vaginitis, vulval eczema, tinea corporis etc., can show as that pudendum normally also can show as erythema, pimple, sepage, chaps, lichenization etc., for the commonly encountered diseases of gynecological or department of dermatologry, there is touching not healing and relapse rate high, have a strong impact on patient's physiology and mental health.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of pruritus vulvae.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of pruritus vulvae, it is to be made by weight by following bulk drugs: flag 10-30 part, Chinese mugwort 1-30 part in thousand, Herba Caryopteridis Terniflorae 1-20 part, Flos seu Radix Impatientis nolitangeris 1-20 part, Ramulus Cinnamomi 1-20 part, Herba Blumeae clarkei 1-20 part, Radix Paeoniae Alba 1-20 part, Pseudobulbus Coelogynes corymbosae 1-20 part, Radix Ophiopogonis 1-20 part, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 1-20 part, Radix Angelicae Dahuricae 1-20 part, sting blood red 1-20 part, Folium Mori 1-10 part, Rhizoma Tupistrae Chinensis 1-10 part, Poria 1-10 part, Herba Inulae cappae 1-10 part, Semen Coicis 1-10 part, Herba Elsholtziae Ciliatae 1-10 part and Rhizoma Zingiberis Recens 1-10 part.
Preferably, the medicament for the treatment of pruritus vulvae of the present invention is to be made by weight by following bulk drugs: flag 10-20 part, Chinese mugwort 5-20 part in thousand, Herba Caryopteridis Terniflorae 5-10 part, Flos seu Radix Impatientis nolitangeris 5-15 part, Ramulus Cinnamomi 5-15 part, Herba Blumeae clarkei 5-15 part, Radix Paeoniae Alba 1-10 part, Pseudobulbus Coelogynes corymbosae 1-10 part, Radix Ophiopogonis 1-10 part, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 1-10 part, Radix Angelicae Dahuricae 1-10 part, sting blood red 1-10 part, Folium Mori 1-5 part, Rhizoma Tupistrae Chinensis 1-5 part, Poria 1-5 part, Herba Inulae cappae 1-5 part, Semen Coicis 1-5 part, Herba Elsholtziae Ciliatae 1-5 part and Rhizoma Zingiberis Recens 1-5 part.
More preferably, the medicament for the treatment of pruritus vulvae of the present invention is to be made by weight by following bulk drugs: 10 parts of 15 parts, thousand Chinese mugworts of flag, 8 parts of Herba Caryopteridis Ternifloraes, 9 parts of Flos seu Radix Impatientis nolitangeriss, 8 parts of Ramulus Cinnamomi, 6 parts of Herba Blumeae clarkei, 5 parts of the Radix Paeoniae Albas, 6 parts of Pseudobulbus Coelogynes corymbosaes, 5 parts of Radix Ophiopogonis, 6 parts of Folium Ligustri QuihouiCortex seu Folium Ligustri nitidis, 5 parts of the Radixs Angelicae Dahuricae, sting 2 parts, blood red 5 parts, 3 parts, Folium Mori, 3 parts of Rhizoma Tupistrae Chinensis, 3 parts, Poria, 3 parts of Herba Inulae cappaes, 3 parts of Semen Coiciss, 3 parts of Herba Elsholtziae Ciliataes and Rhizoma Zingiberis Recens.
More preferably, described medicament can be tablet, dispersible tablet, disintegrating tablet, instant, enteric coatel tablets, capsule or lotion.
In compositions of the present invention, Yi Zhiqi, Chinese mugwort, Herba Caryopteridis Terniflorae, Flos seu Radix Impatientis nolitangeris in thousand are monarch drug; Ramulus Cinnamomi, Herba Blumeae clarkei, the Radix Paeoniae Alba, Pseudobulbus Coelogynes corymbosae, Radix Ophiopogonis, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi are ministerial drug; The Radix Angelicae Dahuricae, sting blood red, Folium Mori, Rhizoma Tupistrae Chinensis is adjuvant drug; Poria, Herba Inulae cappae, Semen Coicis, Herba Elsholtziae Ciliatae and Rhizoma Zingiberis Recens are for making medicine, and various composition performance synergism are to produce optimum efficiency.
In order to understand better the present invention, with reference to < < Chinese medicine voluminous dictionary > > second edition (Shanghai science tech publishing house, 2005) explanation of some crude drug that, use in the present invention sees the following form:
The medicament for the treatment of pruritus vulvae of the present invention has the effect of heat-clearing and toxic substances removing, cooling blood for hemostasis, loose addiction detumescence, can effectively treat pruritus vulvae.
The specific embodiment
Below by embodiment, further illustrate the present invention.It should be understood that embodiments of the invention are for the present invention rather than limitation of the present invention are described.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the scope of protection of present invention.Except as otherwise noted, the percent otherwise in the present invention is percetage by weight.
Embodiment lotion of the present invention
Get 15 grams, a flag, 10 grams of Chinese mugworts in thousand, 8 grams of Herba Caryopteridis Ternifloraes, 9 grams of Flos seu Radix Impatientis nolitangeriss, 8 grams of Ramulus Cinnamomi, 6 grams of Herba Blumeae clarkei, 5 grams of the Radix Paeoniae Albas, 6 grams of Pseudobulbus Coelogynes corymbosaes, 5 grams of Radix Ophiopogonis, 6 grams of Folium Ligustri QuihouiCortex seu Folium Ligustri nitidis, 5 grams of the Radixs Angelicae Dahuricae, sting 2 grams, blood red 5 grams, 3 grams, Folium Mori, 3 grams of Rhizoma Tupistrae Chinensis, 3 grams, Poria, 3 grams of Herba Inulae cappaes, 3 grams of Semen Coiciss, 3 grams of Herba Elsholtziae Ciliataes and Rhizoma Zingiberis Recens, add 20000 milliliters, water, in the flask that condenser is housed, at 90 ℃, heat 6 hours, filter, filtrate is lotion of the present invention.
Experimental example
Physical data
100 routine patients all carry out self-Out-patient Department, are simple pruritus vulvae patient.21 years old-64 years old age, average 36.3 years old; 3 months-2a of the course of disease, average 12.4 months.Patient is divided into treatment group 50 examples, matched group 50 examples.In age, the course of disease, symptom, learn and process there was no significant difference (P>0.05) by statistics, there is comparability for two groups.
Treatment group: treat with the lotion of preparing in embodiment.Clean vulvar mucous membrane pruritus place with lotion, clean every day 3 times, use 500 milliliters to clean at every turn 2 minutes.Treatment 1 week continuously.
Matched group adopts 5 grams of Pevisone (Xian-Janssen Pharmaceutical Ltd.) externals to be coated on vulvar mucous membrane pruritus place.Treatment 1 week continuously.
Criterion of therapeutical effect
With reference to the < < of State Administration of Traditional Chinese Medicine traditional Chinese medical science disease Standardization of diagnosis and curative effect > >, formulate criterion of therapeutical effect.Cure: skin lesion all disappears, clinical symptom disappearance; Effective: skin lesion disappears more than 30%; Invalid: skin lesion is not improved or the less than 30% that disappears.
Result
Through treatment, two groups the results are shown in following table.
| Group | Number of cases | Cure | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 50 | 41 | 9 | 0 | 100 |
| Matched group | 50 | 15 | 20 | 15 | 70 |
Model case
× ×, female, 38 years old, on February 12nd, 2013 was medical.Main suit: pruritus vulvae 1 year, repeatedly outbreak.The violent pruritus of the recent pudendum of patient, goes to a doctor in Duo Jia hospital, and once external multiple gynecological lotion (name is not quite clear) and dermatitis equality ointment, heavy when light in the time of after treatment, never thoroughly cures.Training checks: the obvious flushing of vulvar mucous membrane is chapped, slight atrophy, and color and luster is deepened, and slight lichenization appears in partial skin position.Diagnosis: pruritus vulvae.Treat with the lotion of preparing in embodiment.Clean vulvar mucous membrane pruritus place with lotion, clean every day 3 times, use 500 milliliters to clean at every turn 2 minutes.Treatment 1 week continuously.Pruritus obviously alleviates, the disappearance of chapping, and pudendum normal, enjoins it to be careful in one's diet and the adjustment of operating pressure, follows up a case by regular visits to and does not recur for 1 year again.
Lee ×, female, 26 years old, on June 26th, 2013 was medical.Main suit: pruritus vulvae half a year, repeatedly outbreak.Patient is the violent pruritus of pudendum over nearly 1 month.Training checks: the obvious flushing of vulvar mucous membrane is chapped, slight atrophy, and color and luster is deepened, and slight lichenization appears in partial skin position.Diagnosis: pruritus vulvae.Treat with the lotion of preparing in embodiment.Clean vulvar mucous membrane pruritus place with lotion, clean every day 3 times, use 500 milliliters to clean at every turn 2 minutes.Treatment 1 week continuously.Pruritus obviously alleviates, the disappearance of chapping, and pudendum normal, enjoins it to be careful in one's diet and the adjustment of operating pressure, follows up a case by regular visits to and does not recur for 1 year again.
King ×, female, 49 years old, within 2013, JIUYUE was gone to a doctor on the 18th.Main suit: pruritus vulvae 1 year half, repeatedly outbreak.Patient is the violent pruritus of pudendum closely over the past half year.Training checks: the obvious flushing of vulvar mucous membrane is chapped, slight atrophy, and color and luster is deepened, and slight lichenization appears in partial skin position.Diagnosis: pruritus vulvae.Treat with the lotion of preparing in embodiment.Clean vulvar mucous membrane pruritus place with lotion, clean every day 3 times, use 500 milliliters to clean at every turn 2 minutes.Treatment 1 week continuously.Pruritus obviously alleviates, the disappearance of chapping, and pudendum normal, enjoins it to be careful in one's diet and the adjustment of operating pressure, follows up a case by regular visits to and does not recur for 1 year again.
Claims (4)
1. treat the medicament of pruritus vulvae for one kind, it is characterized in that, it is to be made by weight by following bulk drugs: flag 10-30 part, Chinese mugwort 1-30 part in thousand, Herba Caryopteridis Terniflorae 1-20 part, Flos seu Radix Impatientis nolitangeris 1-20 part, Ramulus Cinnamomi 1-20 part, Herba Blumeae clarkei 1-20 part, Radix Paeoniae Alba 1-20 part, Pseudobulbus Coelogynes corymbosae 1-20 part, Radix Ophiopogonis 1-20 part, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 1-20 part, Radix Angelicae Dahuricae 1-20 part, sting blood red 1-20 part, Folium Mori 1-10 part, Rhizoma Tupistrae Chinensis 1-10 part, Poria 1-10 part, Herba Inulae cappae 1-10 part, Semen Coicis 1-10 part, Herba Elsholtziae Ciliatae 1-10 part and Rhizoma Zingiberis Recens 1-10 part.
2. the medicament for the treatment of pruritus vulvae according to claim 1, it is characterized in that, it is to be made by weight by following bulk drugs: flag 10-20 part, Chinese mugwort 5-20 part in thousand, Herba Caryopteridis Terniflorae 5-10 part, Flos seu Radix Impatientis nolitangeris 5-15 part, Ramulus Cinnamomi 5-15 part, Herba Blumeae clarkei 5-15 part, Radix Paeoniae Alba 1-10 part, Pseudobulbus Coelogynes corymbosae 1-10 part, Radix Ophiopogonis 1-10 part, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 1-10 part, Radix Angelicae Dahuricae 1-10 part, sting blood red 1-10 part, Folium Mori 1-5 part, Rhizoma Tupistrae Chinensis 1-5 part, Poria 1-5 part, Herba Inulae cappae 1-5 part, Semen Coicis 1-5 part, Herba Elsholtziae Ciliatae 1-5 part and Rhizoma Zingiberis Recens 1-5 part.
3. the medicament for the treatment of pruritus vulvae according to claim 2, it is characterized in that, it is to be made by weight by following bulk drugs: 10 parts of 15 parts, thousand Chinese mugworts of flag, 8 parts of Herba Caryopteridis Ternifloraes, 9 parts of Flos seu Radix Impatientis nolitangeriss, 8 parts of Ramulus Cinnamomi, 6 parts of Herba Blumeae clarkei, 5 parts of the Radix Paeoniae Albas, 6 parts of Pseudobulbus Coelogynes corymbosaes, 5 parts of Radix Ophiopogonis, 6 parts of Folium Ligustri QuihouiCortex seu Folium Ligustri nitidis, 5 parts of the Radixs Angelicae Dahuricae, sting 2 parts, blood red 5 parts, 3 parts, Folium Mori, 3 parts of Rhizoma Tupistrae Chinensis, 3 parts, Poria, 3 parts of Herba Inulae cappaes, 3 parts of Semen Coiciss, 3 parts of Herba Elsholtziae Ciliataes and Rhizoma Zingiberis Recens.
4. according to the medicament of the treatment pruritus vulvae described in any one in claims 1 to 3, it is characterized in that, described medicament can be tablet, dispersible tablet, disintegrating tablet, instant, enteric coatel tablets, capsule or lotion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410026197.6A CN103736068B (en) | 2014-01-21 | 2014-01-21 | A kind of medicament for the treatment of pruritus vulvae |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410026197.6A CN103736068B (en) | 2014-01-21 | 2014-01-21 | A kind of medicament for the treatment of pruritus vulvae |
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| Publication Number | Publication Date |
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| CN103736068A true CN103736068A (en) | 2014-04-23 |
| CN103736068B CN103736068B (en) | 2015-11-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410026197.6A Expired - Fee Related CN103736068B (en) | 2014-01-21 | 2014-01-21 | A kind of medicament for the treatment of pruritus vulvae |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3046541A1 (en) * | 2016-01-12 | 2017-07-14 | Soc Ind Limousine D'application Biologique | ACTIVE PRINCIPLE OBTAINED FROM OPHIOPOGON JAPONICUS FOR THE TREATMENT OF ATOPIC DERMATITIS |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840169A (en) * | 2006-01-12 | 2006-10-04 | 魏敏政 | A Chinese medicinal composition and its application in relieving pain and skin itching |
| CN102846934A (en) * | 2011-06-30 | 2013-01-02 | 苏州知微堂生物科技有限公司 | Preparation technology and production method for an integrated new formulation of warming channel decoction |
| CN103071085A (en) * | 2013-01-14 | 2013-05-01 | 上海浦东高星生物技术研究所 | Chinese patent drug for curing pruritus vulvae of old women |
-
2014
- 2014-01-21 CN CN201410026197.6A patent/CN103736068B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1840169A (en) * | 2006-01-12 | 2006-10-04 | 魏敏政 | A Chinese medicinal composition and its application in relieving pain and skin itching |
| CN102846934A (en) * | 2011-06-30 | 2013-01-02 | 苏州知微堂生物科技有限公司 | Preparation technology and production method for an integrated new formulation of warming channel decoction |
| CN103071085A (en) * | 2013-01-14 | 2013-05-01 | 上海浦东高星生物技术研究所 | Chinese patent drug for curing pruritus vulvae of old women |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3046541A1 (en) * | 2016-01-12 | 2017-07-14 | Soc Ind Limousine D'application Biologique | ACTIVE PRINCIPLE OBTAINED FROM OPHIOPOGON JAPONICUS FOR THE TREATMENT OF ATOPIC DERMATITIS |
| WO2017121965A1 (en) * | 2016-01-12 | 2017-07-20 | Societe Industrielle Limousine D'application Biologique | Active ingredient obtained from ophiopogon japonicus, for the treatment of atopic dermatitis |
| US11311596B2 (en) | 2016-01-12 | 2022-04-26 | Societe Industrielle Limousine D'application Biologique | Active ingredient obtained from Ophiopogon japonicus for the treatment of atopic dermatitis |
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| Publication number | Publication date |
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| CN103736068B (en) | 2015-11-25 |
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Granted publication date: 20151125 Termination date: 20170121 |