CN103735694A - Traditional Chinese medicinal formula capable of relieving functional diarrhea and preparation method thereof - Google Patents
Traditional Chinese medicinal formula capable of relieving functional diarrhea and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal formula capable of relieving functional diarrhea. The traditional Chinese medicinal formula mainly comprises the following raw materials in parts by weight: 2-6 parts of cuttle bone, 4-10 parts of fructus evodiae, 6-10 parts of elecampane, 1-3 parts of concha arcae, 6-15 parts of dried alum, 5-12 parts of magnolia obavata, 8-15 parts of rhizoma coptidis, 6-12 parts of nutgall, 14-26 parts of apple vinegar, and 5-12 parts of sesame oil. The traditional Chinese medicinal formula is capable of relieving functional diarrhea with a curative rate of 100%, can improve the poor appetite situation of a patient after taking, not only can relieve the functional diarrhea for the patient, but also can tonify spleen and invigorate stomach. The traditional Chinese medicine formula takes simple and feasible traditional Chinese medicines as raw materials, can become effective rapidly, is free from any toxic or side effects, quickly relieves the pain for the patient, and plays a good effective role for the functional diarrhea due to too strong gastrointestinal function, and too fast gastrointestinal motility.
Description
Technical field
The invention discloses a kind of Chinese medicinal formulae, Chinese medicinal formulae of especially a kind of mitigation capability diarrhoea and preparation method thereof.The invention belongs to Chinese medicine field.
Background technology
Functional diarrhea refers to the diarrhoea without any antibacterial, viral infection, generally by gastrointestinal function excessively strong (gastrointestinal rubs too fast), is caused, primary disease is that one shows as and do not accompany stomachache, the disease of persistence or recurrent solution soft stool, watery stool.Bristol area, England had once been carried out Epidemiological study to local resident for feces character, by continuous 3 shapeless functional diarrheas that are just defined as of row.According to such diagnostic criteria investigation, find, functional diarrhea is more more common in 50 years old and 50 years old above women, its sickness rate reaches 3.1%, and the right side of fifty women's sickness rate is 1.7%, due to 50 years old be women's age of meuopause of this area just, therefore, the variation of supposition hormonal readiness may be to cause one of risk factor of women's functional diarrhea.
At present, less to the pathogenetic research of functional diarrhea, in diet, some are difficult for the carbohydrate absorbing, and may bring out patient's diarrhoea.Fructose, sorbitol and mannitol etc. in lactose-intolerant person's EDIBLE LACTOSE, " sugar-free " diet all can cause diarrhoea.Ethanol can make small intestinal edema, sodium malabsorption and cause diarrhoea.
Intestinal transport Time dependent feces character; the true most important pathophysiology abnormal change of property diarrhea patient is to accelerate the intestinal transport time; the important pathophysiology of functional diarrhea patient is abnormal; occur in small intestinal or at colon, be that intestinal power abnormality or sensitivity change and is still not clear actually.The quickening of IBS patient's Colonic transit time is accelerated relevant with small intestinal transhipment.Small intestinal transhipment accelerates to make the food debris that does not more obtain catapepsis to enter colon, and in the food of catapepsis, do not contain short chain carbohydrate and peptide chain, and before being decomposed into short-chain fatty acid by intestinal microbial population, osmotically active is very strong. and moisture in enteric cavity is increased.Small intestinal transhipment accelerates also to make the products with secretion effect more, as long-chain fatty acid, two hydroxyl cholic acid etc. enters colon, produces cathartic effect.
There is not inevitable dependency in stool and colon transfer room, the generation of pseudodiarrhea is is mostly because Rectal Sensitivity increases.No matter whether the IBS patient that Rectal Sensitivity increases have diarrhoea all to show as defecation intention frequently, and the micturition frequency that stool causes with hypersensitivity bladder conventionally increases relevant.Rectal Sensitivity can be improved by hypnotherapy, shows that Nervous and Mental Factors also has certain effect in morbidity.
As everyone knows, acute anxiety often can cause diarrhoea, and most healthy populations, especially young woman can affect bowl evacuation habit under stress state, but its pathogenesis is not clear and definite yet at present.Emotion changes has the effect of short colonic activity, but this phenomenon is in normal person and diarrhea patient and zero difference.For IBS, still less to the correlation research of functional diarrhea and chronic anxiety and stress state.
In the method for existing mitigation capability diarrhoea, application publication number CN 103285165 A(application numbers 201310183758.9) a kind of Chinese medicine for the treatment of functional diarrhea disclosed, following component, consist of, the weight portion of each component is: Radix Ginseng 1-3, Pericarppium arachidis hypogaeae 10-12, Galla Chinensis 8-10, Rhizoma Coptidis 10-12, Rhizoma Atractylodis Macrocephalae (parched) 8-10, Herba Pogostemonis 10-12, Herba Ludwigiae Prostratae 10-12, Fructus Crataegi (parched to brown) 10-12, Fructus Mume 10-12, Radix Ilicis Asprellae 8-10, Radix Notoginseng 3-5, Flos Camelliae Japonicae 5-8, Semen Granati 8-10, Rhizoma Chuanxiong 5-8, Terra Flava Usta 10-12.Application publication number CN 103349695 A(application numbers 201310209108.7) a kind of Chinese medicine for the treatment of functional diarrhea disclosed, following component, consist of, the weight portion of each component is: Radix Codonopsis 10-12, Rhizoma Atractylodis Macrocephalae (parched) 9-11, Poria 10-12, Polyalthia nemoralis A. D C. 10-12, Galla Chinensis 5-8, Radix Notoginseng 3-5, Rhizoma Coptidis 3-5, Semen Myristicae 5-8, Radix anthrisci 10-12, Flos Granati 10-12, Fructus Aurantii 5-8, Pericarpium Citri Reticulatae 5-8, Fructus Crataegi 10-12, Herb Gynostemmae Pentaphylli 10-12, Radix Ginkgo 10-12.Application publication number CN 102716406 A(application numbers 201210156498.1) a kind of pill for the treatment of functional diarrhea, the component that contains following weight portion disclosed: Radix Codonopsis 18-22, Rhizoma Atractylodis Macrocephalae (parched) 14-16, Poria 14-16, Pericarpium Citri Reticulatae 8-10, Radix Paeoniae Alba (parched) 14-16, Radix Glycyrrhizae 5-7, Fructus Amomi 3-5, carbonized Fructus Mume 8-10, Radix Puerariae 14-16, Radix Scutellariae (parched) 8-12, Radix Ginseng 1-2, Fructus Evodiae 1-2, Rhizoma Cyperi 1-2, hair ash 1-2, Fructus Schisandrae Chinensis 1-2, Herba Euphorbiae Humifusae 1-2, Fructus Rosae Laevigatae 1-2, Semen Plantaginis 3-5, Fructus Psoraleae 3-5, Radix Aucklandiae (Radix Vladimiriae) 3-5, Rhizoma Corydalis 3-5.Though functional diarrhea effect is good at present existing patent, but its preparation method complexity, and narrow application range, and be not suitable for child.
Summary of the invention
For the present situation of existing mitigation capability diarrhoea medicine deficiency, one of object of the present invention is to provide a kind of Chinese medicinal formulae of mitigation capability diarrhoea, have and make simply, action effect is obvious, the feature such as applied widely, and it adopts comparatively common in the localities Chinese crude drug as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicinal formulae.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of Chinese medicinal formulae of mitigation capability diarrhoea, taking off the primary raw material of stating weight proportion is prepared from: Os Sepiae 2-6 part, Fructus Evodiae 4-10 part, Radix Aucklandiae 6-10 part, Concha Arcae 1-3 part, dried Alumen 6-15 part, Cortex Magnoliae Officinalis 5-12 part, Rhizoma Coptidis 8-15 part, Galla Turcica (Galla Helepensis) 6-12 part, apple vinegar 14-26 part, Oleum Sesami 5-12 part.
Foregoing Chinese medicinal formulae, preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: Os Sepiae 3-5 part, Fructus Evodiae 6-8 part, Radix Aucklandiae 7-9 part, Concha Arcae 1.5-2.5 part, dried Alumen 9-12 part, Cortex Magnoliae Officinalis 8-10 part, Rhizoma Coptidis 11-13 part, Galla Turcica (Galla Helepensis) 8-10 part, apple vinegar 18-23 part, Oleum Sesami 7-10 part.
Foregoing Chinese medicinal formulae, better preferred scheme is, takes off the primary raw material of stating weight proportion and is prepared from: 4 parts of Os Sepiae, 7 parts of Fructus Evodiaes, 8 parts of the Radix Aucklandiae, 2 parts of Concha Arcaes, 11 parts of dried Alumens, 9 parts of Cortex Magnoliae Officinalis, 12 parts of Rhizoma Coptidis, 9 parts of Galla Turcica (Galla Helepensis)s, 20 parts of apple vinegars, 8 parts, Oleum Sesami.
According to the preparation method of arbitrary described Chinese medicinal formulae above, preferred scheme is that step is as follows:
1. Fructus Evodiae, the Radix Aucklandiae, dried Alumen, Cortex Magnoliae Officinalis and Rhizoma Coptidis are fried to 8-15 minute with slow fire, the air dry of drying in the air after stir-fry is sallow to surface is dry, pulverizes 90-120 mesh sieve, obtains medicamental pulverata standby;
2. by Os Sepiae, Concha Arcae and Galla Turcica (Galla Helepensis) pulverization, cross 80-100 mesh sieve, obtain medicamental pulverata standby;
3. by step 1. in gained medicamental pulverata with boiling water punching, melt, wait to dry in the air to temperature 45 C-65 ℃, add apple vinegar to stir, gained is oral medicine, three's weight proportion is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami be medicamental pulverata consumption 0.3-0.7 doubly.
Foregoing preparation method, preferred scheme is that step 1. slow fire is fried 10-13 minute (preferably 12 minutes).
Foregoing preparation method, preferred scheme is that 1. step crosses 95-115 mesh sieve (preferably 110 mesh sieves).
Foregoing preparation method, preferred scheme is that 2. step crosses 85-95 mesh sieve (preferably 90 mesh sieves).
Foregoing preparation method, preferred scheme is, step 3. dry in the air to temperature 50 C-60 ℃ (preferably 55 ℃).
Foregoing preparation method, preferred scheme is that the step 4. consumption of Oleum Sesami is doubly (preferably 0.5 times) of 0.4-0.6 of medicamental pulverata consumption.
The application of Chinese medicinal formulae described in the present invention also provides when the medicine of preparation treatment acute diarrhea, infantile diarrhea and chronic diarrhea.
Using method: for making Chinese medicinal formulae of the present invention reach optimum therapeuticing effect, oral medicine 2 times on the one, took one hour ante cibum of morning and evening, and medicine for external use 1 time on the one is got 5-8g at every turn, is placed on adhesive plaster and is attached to SHENQUE acupoint 6 hours.
This Chinese medicinal formulae is applicable to the patient of each age group, inside use the effect that all can play rapid recovery functional diarrhea with medicine for external use, therefore inside and outside can selecting according to practical situation, use simultaneously or select one to use, and can to dose, suitably increase and decrease according to patient age, more flexible on application method.
A Chinese medicinal formulae for mitigation capability diarrhoea, the pharmacological effect of each crude drug is respectively:
Os Sepiae: have another name called: flower rock, numb black Quarry.Medicine name: Endoconcha Sepiae.Different name: Endoconcha Sepiae crow Quarry bone, sepia bone, cuttlefish lid.Salty, puckery, temperature.Return spleen, kidney channel.Astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, sore.For Peptic Ulcers, hyperchlorhydria, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge, stomachache acid regurgitation; External treatment bleeding due to trauma, the many pus of skin ulcer.Dehumidifying, antacid, hemostasis, sore.The acid regurgitation that treats for stomachache, tells, nosebleed, hematemesis, has blood in stool, and bleeding not during menses, amenorrhea due to blood depletion, stomachache lump in the abdomen, intermittent fever of deficiency type dysentery, the rotten skin ulcer of the erosion of the vulva.
Fructus Evodiae: Fructus Evodiae (formal name used at school Tetradium ruticarpum, original name Euodia ruticarpa), another name Fructus Evodiae, tea is peppery, paint spicy, smelly spicy tree, the deep and remote son of Zuo Lichun, rice spicy etc.Nature and flavor: pungent, bitter, heat; Slightly poisonous.Gui Jing: return liver, spleen, stomach, kidney channel.Effect: dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.Cure mainly: for the sun headache of fainting, colic of cold type stomachache, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, Diarrhoea; External treatment aphtha, hypertension.
The Radix Aucklandiae: nature and flavor: pungent, bitter, temperature.Gui Jing: return spleen, stomach, large intestine, three warmers, gallbladder meridian.Effect: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Cure mainly: for breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).Stomachache is used for having loose bowels.
Concha Arcae: have another name called Carnis Arca inflata shell, watt room, blood clam skin, row of tiles on a roof clam skin, for Carnis Arca inflata section Carnis Arca inflata belongs to the shell that animal Scapharca subcrenata, Scapharca broughtonii and Tegillarca granosa belong to animal Tegillarca granosa.The property of medicine: matter heavily fortified point, sweet in the mouth, salty, property is flat.Composition: main component is calcium carbonate, also contains a small amount of calcium phosphate and magnesium, ferrum, silicate.According to modern pharmacological research, find, this medical instrument has the effect of expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache, for pertinacious phlegm chronic cough, and stomachache acid regurgitation, traumatic hemorrhage, gastric and duodenal ulcers.
Dried Alumen: have another name called calcined Alumen.Get the Alumen of choosing clean, put in marmite heating and dissolve and be calcined to dried-uply, take out, for irregular crystalline solid, not of uniform size.Colourless, transparent or semitransparent, surface is slightly level and smooth or uneven, and the fine and closely woven vertical rib of tool, has hyaloid gloss.Matter is hard and crisp, easily smashes.Feeble QI, taste is micro-sweet and puckery.So that color is white, transparent, matter is hard and crisp, free from admixture person is as good.Soluble in water or glycerol, is insoluble to ethanol.Aqueous solution shows aluminum salt, potassium salt reacts with the various of sulfate.Expectorant, dampness, antidiarrheal, hemostasis, removing toxic substances, parasite killing.Control epilepsy, sore throat, remorse saliva is stopped up very, hepatitis, jaundice, general edema with yellowish skin, duodenal ulcer, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite.
Cortex Magnoliae Officinalis: Cortex Magnoliae Officinalis, removing dampness by means of aromatics Chinese medicine, cures mainly: stagnation of QI due to dyspepsia; Abdominal distention constipation; Retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea; Expectorant is stopped up QI rising in reverse order; Fullness in the chest is breathed with cough.Come from < < Sheng Nong's herbal classic > >.Be now that national II level is laid special stress on protecting wild plant.Nature and flavor: hardship; Pungent; Warm in nature.
Gui Jing: spleen channel; Stomach warp; Large intestine channel.Function: circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma.Cure mainly: stagnation of QI due to dyspepsia; Abdominal distention constipation; Retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea; Expectorant is stopped up QI rising in reverse order; Fullness in the chest is breathed with cough.
Rhizoma Coptidis: nature and flavor: hardship, cold.Gui Jing: GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication.
Cure mainly: for cold and heat, tie mutually damp and hot middle resistance, feeling of fullness vomiting.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Galla Turcica (Galla Helepensis): have another name called black stone, without infanticide, for gall wasps section cynipid belongs to the insect gall that the parasitized larvaes of insecticide gall wasps produces on Fagaceae oak plant Galla Turcica (Galla Helepensis) tree sprout.The property of medicine: this product is spherical in shape, has short handle, and outer surface Lycoperdon polymorphum Vitt has verruca, and matter heavily fortified point is thick, and bitter in the mouth is warm in nature.Composition: Galla Turcica (Galla Helepensis) insect gall is containing turkish gallotannin, gallic acid and resin etc.According to modern pharmacological research, find, this medical instrument has astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs, astringes the lung, the effect of hemostasis and pain-relieving, for chronic diarrhea chronic dysentery, and night sweat, cough, spitting of blood, has blood in stool.
Apple vinegar: the former vinegar of Fructus Mali pumilae forming through fermentation with Sucus Mali pumilae, the pectin wherein containing is conducive to the growth of probiotics in intestinal, sour in the mouth, sweet.
Oleum Sesami: English name OLEUM SESAMI.Base is former: this product is the fatty oil that the mature seed of Pedaliaceae plant sesame obtains with milling process.Purposes: lubricant and excipient, for oral administration can intestine moistening, lung moistening; Be used as ointment machin plaster substrate (Oleum Sesami of using in the present invention is extracted by Semen Sesami) outward.
The principle of Chinese medicinal formulae of the present invention based on Chinese medicine mitigation capability diarrhoea, the Chinese medicinal material of selecting all has the effect of mitigation capability diarrhoea, spleen invigorating, stomach function regulating, and oral medicine taste is sour-sweet, has avoided the embarrassment of good medicine tastes bitter, this Chinese medicinal formulae compatibility is proper, is applicable to the patient of each age group.
Compared with prior art, its technique effect is embodied in the present invention:
(1) extraction process is simple, and extraction efficiency is high, and energy consumption and loss are little, and cost is low;
(2) increase nutritional labeling and active ingredient, but do not changed the curative effect that each crude drug cooperatively interacts;
(3) long-term taking this product has special efficacy to acute diarrhea, chronic diarrhea, functional diarrhea, more can improve immunity.
Accompanying drawing explanation
Fig. 1 is that after taking prescription of the present invention, symptom of diarrhea obviously improves or disappearance situation design sketch;
Fig. 2 takes appetite recovery situation design sketch after prescription of the present invention.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1a Chinese medicinal formulae for mitigation capability diarrhoea, takes off the primary raw material of stating weight proportion and is prepared from (getting 10g for every part): 2 parts of Os Sepiae, 4 parts of Fructus Evodiaes, 6 parts of the Radix Aucklandiae, 1 part of Concha Arcae, 6 parts of dried Alumens, 5 parts of Cortex Magnoliae Officinalis, 8 parts of Rhizoma Coptidis, 6 parts of Galla Turcica (Galla Helepensis)s, 14 parts of apple vinegars, 5 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicinal formulae, step is:
1. Fructus Evodiae, the Radix Aucklandiae, Cortex Magnoliae Officinalis and Rhizoma Coptidis are fried 8 minutes with slow fire, the air dry of drying in the air after stir-fry is sallow to surface is dry, pulverizes 90 mesh sieves, obtains medicamental pulverata standby;
2. by Os Sepiae, Concha Arcae, dried Alumen and Galla Turcica (Galla Helepensis) pulverization, cross 80 mesh sieves, obtain medicamental pulverata standby;
3. by step 1. in gained medicamental pulverata with boiling water punching, melt, wait to dry in the air to temperature 45 C, add apple vinegar to stir, gained is oral medicine, three's weight proportion is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.3 times of medicamental pulverata consumption.
model case onezhu XX, female, 20 years old, Jinan, Shandong Province people.Symptom: when in December, 2012 is examined, the egg soup sample of suffering from diarrhoea the same day has just reached 10 times, without having blood in stool vomiting phenomenon, goes to hospital to conduct a survey and is diagnosed as functional diarrhea.
Use the embodiment of the present invention 1 gained Chinese medicinal formulae, get medicine for external use 8g and be all affixed on infant SHENQUE acupoint with being placed on adhesive plaster, after 3 hours, patient's symptom of diarrhea obviously alleviates, and 4 as a child again without the phenomenon of suffering from diarrhoea.Supper is got oral medicine 10g for last hour and is drunk, and second day supper patient appetite is normal, after meal also without diarrhoea phenomenon.
embodiment 2a Chinese medicinal formulae for mitigation capability diarrhoea, takes off the primary raw material of stating weight proportion and is prepared from (getting 5g for every part): 6 parts of Os Sepiae, 10 parts of Fructus Evodiaes, 10 parts of the Radix Aucklandiae, 3 parts of Concha Arcaes, 15 parts of dried Alumens, 12 parts of Cortex Magnoliae Officinalis, 15 parts of Rhizoma Coptidis, 12 parts of Galla Turcica (Galla Helepensis)s, 26 parts of apple vinegars, 12 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicinal formulae, step is:
1. Fructus Evodiae, the Radix Aucklandiae, Cortex Magnoliae Officinalis and Rhizoma Coptidis are fried 15 minutes with slow fire, the air dry of drying in the air after stir-fry is sallow to surface is dry, pulverizes 120 mesh sieves, obtains medicamental pulverata standby;
2. by Os Sepiae, Concha Arcae, dried Alumen and Galla Turcica (Galla Helepensis) pulverization, cross 100 mesh sieves, obtain medicamental pulverata standby;
3. by step 1. in gained medicamental pulverata with boiling water punching, melt, wait to dry in the air to 65 ℃ of temperature, add apple vinegar to stir, gained is oral medicine, three's weight proportion is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.7 times of medicamental pulverata consumption.
model case twopoplar XX, man, 5 years old, Zhengzhou, henan people from city.Symptom: when in June, 2013, infant was examined, the egg soup sample of suffering from diarrhoea the same day has just reached 5 times, without having blood in stool vomiting phenomenon, goes examination in hospital to be diagnosed as functional diarrhea.
Use the embodiment of the present invention 2 gained Chinese medicinal formulaes, get medicine for external use 5g and be all affixed on infant SHENQUE acupoint with being placed on adhesive plaster, after 2 hours, infant symptom of diarrhea obviously alleviates, and 5 as a child again without the phenomenon of suffering from diarrhoea.Supper is got oral medicine 10g for last hour and is drunk, and the appetite of supper infant is normal, after meal also without diarrhoea phenomenon.
embodiment 3a Chinese medicinal formulae for mitigation capability diarrhoea, takes off the primary raw material of stating weight proportion and is prepared from (getting 15g for every part): 3 parts of Os Sepiae, 6 parts of Fructus Evodiaes, 7 parts of the Radix Aucklandiae, 1.5 parts of Concha Arcaes, 9 parts of dried Alumens, 8 parts of Cortex Magnoliae Officinalis, 11 parts of Rhizoma Coptidis, 8 parts of Galla Turcica (Galla Helepensis)s, 18 parts of apple vinegars, 7 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicinal formulae, step is:
1. Fructus Evodiae, the Radix Aucklandiae, Cortex Magnoliae Officinalis and Rhizoma Coptidis are fried 10 minutes with slow fire, the air dry of drying in the air after stir-fry is sallow to surface is dry, pulverizes 95 mesh sieves, obtains medicamental pulverata standby;
2. by Os Sepiae, Concha Arcae, dried Alumen and Galla Turcica (Galla Helepensis) pulverization, cross 85 mesh sieves, obtain medicamental pulverata standby;
3. by step 1. in gained medicamental pulverata with boiling water punching, melt, wait to dry in the air to temperature 50 C, add apple vinegar to stir, gained is oral medicine, three's weight proportion is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.4 times of medicamental pulverata consumption.
model case threefield XX, female, 15 years old, Jinan, Shandong Province people, the student in certain middle school, eaten after meal morning in the dining room of school, sensation stomach-ache, general weakness, the egg soup sample of suffering from diarrhoea the same day has just reached 8 times, and without having blood in stool vomiting phenomenon, belly has cluck,coo sound, goes examination in hospital to be diagnosed as functional diarrhea.
Use the embodiment of the present invention 3 gained Chinese medicinal formulaes, get medicine for external use 6g and be all affixed on infant SHENQUE acupoint with being placed on adhesive plaster, after 4 hours, patient's symptom of diarrhea obviously alleviates, and the phenomenon of suffering from diarrhoea after 5 hours disappears substantially.Supper is got oral medicine 18g for last hour and is drunk, and second day breakfast patient appetite is normal, after meal also without diarrhoea phenomenon.
embodiment 4a Chinese medicinal formulae for mitigation capability diarrhoea, takes off the primary raw material of stating weight proportion and is prepared from (getting 20g for every part): 5 parts of Os Sepiae, 8 parts of Fructus Evodiaes, 9 parts of the Radix Aucklandiae, 2.5 parts of Concha Arcaes, 12 parts of dried Alumens, 10 parts of Cortex Magnoliae Officinalis, 13 parts of Rhizoma Coptidis, 10 parts of Galla Turcica (Galla Helepensis)s, 23 parts of apple vinegars, 10 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicinal formulae, step is:
1. Fructus Evodiae, the Radix Aucklandiae, Cortex Magnoliae Officinalis and Rhizoma Coptidis are fried 13 minutes with slow fire, the air dry of drying in the air after stir-fry is sallow to surface is dry, pulverizes 115 mesh sieves, obtains medicamental pulverata standby;
2. by Os Sepiae, Concha Arcae, dried Alumen and Galla Turcica (Galla Helepensis) pulverization, cross 95 mesh sieves, obtain medicamental pulverata standby;
3. by step 1. in gained medicamental pulverata with boiling water punching, melt, wait to dry in the air to temperature 60 C, add apple vinegar to stir, gained is oral medicine, three's weight proportion is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.6 times of medicamental pulverata consumption.
embodiment 5a Chinese medicinal formulae for mitigation capability diarrhoea, takes off the primary raw material of stating weight proportion and is prepared from (getting 30g for every part): 4 parts of Os Sepiae, 7 parts of Fructus Evodiaes, 8 parts of the Radix Aucklandiae, 2 parts of Concha Arcaes, 11 parts of dried Alumens, 9 parts of Cortex Magnoliae Officinalis, 12 parts of Rhizoma Coptidis, 9 parts of Galla Turcica (Galla Helepensis)s, 20 parts of apple vinegars, 8 parts, Oleum Sesami.
The preparation method of above-mentioned Chinese medicinal formulae, step is:
1. Fructus Evodiae, the Radix Aucklandiae, Cortex Magnoliae Officinalis and Rhizoma Coptidis are fried 12 minutes with slow fire, the air dry of drying in the air after stir-fry is sallow to surface is dry, pulverizes 110 mesh sieves, obtains medicamental pulverata standby;
2. by Os Sepiae, Concha Arcae, dried Alumen and Galla Turcica (Galla Helepensis) pulverization, cross 90 mesh sieves, obtain medicamental pulverata standby;
3. by step 1. in gained medicamental pulverata with boiling water punching, melt, wait to dry in the air to 55 ℃ of temperature, add apple vinegar to stir, gained is oral medicine, three's weight proportion is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami is 0.5 times of medicamental pulverata consumption.
experimental examplein order to verify the definite curative effect of this Chinese medicinal formulae mitigation capability diarrhoea, randomly draw to examine diarrhea patient 30 people (gastrointestinal function is excessively strong, gastrointestinal rub the too fast functional diarrhea causing), the mean age is 45 years old, minimum 10 years old, maximum 75 years old.According to the state of an illness and pathology, be divided into administration group and matched group, every group of each 15 people, guarantee that administration group and matched group situation are basically identical, wherein respectively organize functional diarrhea patient 8 people.
Administration group is used the embodiment of the present invention 5 gained Chinese medicinal formulaes every day, and for making Chinese medicinal formulae of the present invention reach optimum therapeuticing effect, oral medicine 2 times on the one, one hour ante cibum of morning and evening.Medicine for external use 1 time on the one is got 5-8g at every turn, is placed on adhesive plaster and is attached to SHENQUE acupoint 6 hours.Experimental group is used the medicine (as XIELITING, the medicine of the conventional mitigation capability diarrhoea such as umbilicus subsides) of other mitigation capability diarrhoea.Criterion: cure, malaise symptoms disappears; Effectively, malaise symptoms disappears substantially; Invalid, malaise symptoms is unchanged.
Observe 2 days time limits, observed content is as follows:
1, take medicine in 1-6 hour, every 2 hours, observe once, record the number that disease is obviously alleviated, result is as accompanying drawing 1:
Analyze: from accompanying drawing 1, can find out, though Chinese medicinal formulae of the present invention is Chinese medicine preparation, but mitigation capability diarrhoea speed and other mitigation capabilitys diarrhoea medicine class are basic identical, substantially can obviously improve patient's symptom of diarrhea in 1-4 hour, reach rapid recovery patient suffering's object.
2, to vomiting in each group and with 8 patients of diarrhoea taking medicine in 2 days, get 3 appetite recovery situation statistics records after they being taken medicine with meal (being respectively first day lunch, first day dinner, and the lunch of second day), result is as accompanying drawing 2:
Analyze: from accompanying drawing 2, can find out, Chinese medicinal formulae of the present invention can make diarrhoea the patient with vomiting phenomenon, in the shorter time, recover its appetite taking medicine, for patient's continuation rehabilitation and the absorption of nutrition are laid a good foundation.
3, matched group is taken other functional diarrhea medicines and experimental group is taken Chinese medicine composition Comparison of therapeutic of the present invention, and result is as shown in table 1:
Table 1
Analyze: as can be seen from Table 1, take and use Chinese medicine composition effective percentage of the present invention up to 100%, cure rate is up to 93%, and successful is better than taking other functional diarrhea medicines.
efficacy analysis:administration group (Chinese medicinal formulae of the present invention) and matched group all can reach the object of rapid recovery functional diarrhea in 2 days of the observation period, but in matched group diarrhoea and with vomiting phenomenon patient, after taking medicine, the recovery of appetite is starkly lower than administration group.Through clinical trial, prove, Chinese medicinal formulae of the present invention is mitigation capability diarrhoea rapidly, and effective percentage is 100%, and can improve the situation that patient is off one's feed after taking medicine, and can not only be patient's mitigation capability diarrhoea, can also play the effect of spleen-and-stomach-invigorating.Chinese medicinal formulae of the present invention adopts Chinese medicinal material simple and easy to get as raw material, instant effect, and without any side effects, can reach the object of rapid alleviation patient misery, excessively strong to gastrointestinal function, gastrointestinal rubs the too fast functional diarrhea causing good therapeutical effect.
Claims (10)
1. the Chinese medicinal formulae of mitigation capability diarrhoea, it is characterized in that, take off the primary raw material of stating weight proportion and be prepared from: Os Sepiae 2-6 part, Fructus Evodiae 4-10 part, Radix Aucklandiae 6-10 part, Concha Arcae 1-3 part, dried Alumen 6-15 part, Cortex Magnoliae Officinalis 5-12 part, Rhizoma Coptidis 8-15 part, Galla Turcica (Galla Helepensis) 6-12 part, apple vinegar 14-26 part, Oleum Sesami 5-12 part.
2. Chinese medicinal formulae according to claim 1, it is characterized in that, take off the primary raw material of stating weight proportion and be prepared from: Os Sepiae 3-5 part, Fructus Evodiae 6-8 part, Radix Aucklandiae 7-9 part, Concha Arcae 1.5-2.5 part, dried Alumen 9-12 part, Cortex Magnoliae Officinalis 8-10 part, Rhizoma Coptidis 11-13 part, Galla Turcica (Galla Helepensis) 8-10 part, apple vinegar 18-23 part, Oleum Sesami 7-10 part.
3. Chinese medicinal formulae according to claim 1, is characterized in that: take off the primary raw material of stating weight proportion and be prepared from: 4 parts of Os Sepiae, 7 parts of Fructus Evodiaes, 8 parts of the Radix Aucklandiae, 2 parts of Concha Arcaes, 11 parts of dried Alumens, 9 parts of Cortex Magnoliae Officinalis, 12 parts of Rhizoma Coptidis, 9 parts of Galla Turcica (Galla Helepensis)s, 20 parts of apple vinegars, 8 parts, Oleum Sesami.
4. according to the preparation method of the arbitrary described Chinese medicinal formulae of claim 1-3, it is characterized in that, step is as follows:
1. Fructus Evodiae, the Radix Aucklandiae, Cortex Magnoliae Officinalis and Rhizoma Coptidis are fried to 8-15 minute with slow fire, the air dry of drying in the air after stir-fry is sallow to surface is dry, pulverizes 90-120 mesh sieve, obtains medicamental pulverata standby;
2. by Os Sepiae, Concha Arcae, dried Alumen and Galla Turcica (Galla Helepensis) pulverization, cross 80-100 mesh sieve, obtain medicamental pulverata standby;
3. by step 1. in gained medicamental pulverata with boiling water punching, melt, wait to dry in the air to temperature 45 C-65 ℃, add apple vinegar to stir, gained is oral medicine, three's weight proportion is boiling water: medicamental pulverata: apple vinegar=20:5:2;
4. by step 2. gained medicamental pulverata mix homogeneously with Oleum Sesami, stir into pasty state and be medicine for external use, the consumption of Oleum Sesami be medicamental pulverata consumption 0.3-0.7 doubly.
5. preparation method according to claim 4, is characterized in that, step 1. slow fire is fried 10-13 minute (preferably 12 minutes).
6. preparation method according to claim 4, is characterized in that, 1. step crosses 95-115 mesh sieve (preferably 110 mesh sieves).
7. preparation method according to claim 4, is characterized in that, 2. step crosses 85-95 mesh sieve (preferably 90 mesh sieves).
8. preparation method according to claim 4, is characterized in that, step 3. dry in the air to temperature 50 C-60 ℃ (preferably 55 ℃).
9. preparation method according to claim 4, is characterized in that, the step 4. consumption of Oleum Sesami is doubly (preferably 0.5 times) of 0.4-0.6 of medicamental pulverata consumption.
10. the application of the Chinese medicine composition as described in as arbitrary in claim 1-3 when the medicine of preparation treatment acute diarrhea, infantile diarrhea and chronic diarrhea.
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Citations (4)
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| CN1410108A (en) * | 2002-09-18 | 2003-04-16 | 内蒙古自治区包头中药厂 | Medicine for treating diarrhea and its preparation method |
| KR20090010384A (en) * | 2007-07-23 | 2009-01-30 | 김재욱 | Composition of herb medicine for female edema and method for preparing the composition |
| CN101791388A (en) * | 2010-04-12 | 2010-08-04 | 汤永顺 | Traditional Chinese medicine preparation for treating peptic ulcer |
| CN103055143A (en) * | 2012-12-23 | 2013-04-24 | 徐化利 | Traditional Chinese medicine formula for treating gastric ulcer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1410108A (en) * | 2002-09-18 | 2003-04-16 | 内蒙古自治区包头中药厂 | Medicine for treating diarrhea and its preparation method |
| KR20090010384A (en) * | 2007-07-23 | 2009-01-30 | 김재욱 | Composition of herb medicine for female edema and method for preparing the composition |
| CN101791388A (en) * | 2010-04-12 | 2010-08-04 | 汤永顺 | Traditional Chinese medicine preparation for treating peptic ulcer |
| CN103055143A (en) * | 2012-12-23 | 2013-04-24 | 徐化利 | Traditional Chinese medicine formula for treating gastric ulcer |
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