CN103689564A - 一种人参补血剂的制备及其作用 - Google Patents
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Classifications
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
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- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
本发明涉及一种人参补血剂的制备及其作用，属于保健食品领域。人参补血剂主要由人参、熟黄、枸杞和蜂蜜组成的滋阴补血复方制剂。其制法为熟地黄50g、人参30.43g、枸杞30g水煎煮3次，每次30分钟到1小时，分次滤过，合并滤液，加热浓缩提取液，加入蜂蜜以及糖粉和糊精等制颗粒剂的辅料，制颗粒，干燥，整粒，密封包装，即得。该发明涉及的人参补血剂制备方便，产品能够预防和治疗血虚症，改善贫血血虚的症状，起到辅助治疗和保健的作用。
Description
技术领域
本发明涉及一种人参补血剂的制备及其作用，属于保健食品领域。
背景技术
血虚为中医名词，指体内阴血亏损的病理现象。可由失血过多，或久病阴血虚耗，或脾胃功能失常，水谷精微不能化生血液等所致。由于气与血有密切关系，故血虚每易引起气虚，而气虚不能化生血液，又为形成血虚的一个因素。血虚是血液失常的一种表现，是指血液生成不足或血的濡养功能减退的一种病理状态。血虚证：心血虚或肝血不足所致的面色萎黄、唇甲苍白、头晕眼花、心慌心悸，以及妇女月经不调等血虚证。血虚主症为面色萎黄，眩晕，心悸，失眠，脉虚细等。熟地黄玄参科植物地黄 Rehmannia glutinosa Libosch的干燥根经过加工炮制而成。人参 五加科植物人参 Panax ginseng C.A.Mey. 的干燥根，主产吉林省。人参大补元气，补脾益肺，生津止渴，安神益智主治气虚欲脱脉散欲绝，脾气虚弱的食欲不振呕吐泄，脾胃虚弱的气短脉虚自汗，热病津伤的口渴消渴证，心神不安失眠多梦惊悸健忘，药理研究发现人参具有强心、抗心肌缺血、提高机体免疫力、调节糖代谢、促进蛋白合成、促胆固醇排泄。
发明内容
本发明公开了一种补血剂的制备方法。
人参补血剂主要由人参、熟黄、枸杞和蜂蜜等中药组成的滋阴补血复方制剂。
人参补血剂
[处方] 熟地黄 50g
人参（去芦） 30.43g
枸杞 30g
蜂蜜 20g
[制法] 熟地黄、人参、枸杞水煎煮3次，每次30分钟到1小时，分次滤过，合并滤液，加热浓缩提取液，加入制颗粒剂的辅料如糖粉和糊精制颗粒，干燥，整粒，密封包装。即得。
[性状] 本品为棕褐色的颗粒状，气香，味甘。
方中人参味甘微苦，温而不燥，既能补脾又能润肺，为君药。熟地补血。枸杞助人参健脾补中，蜂蜜既能润肺止咳，又能调和诸药，亦为佐使。颗粒剂易于服用和保存。
实验中观察到人参补血剂不但对气虚动物DNA、RNA具有良好的调整作用，使痛阈提高。这些作用表明人参补血剂对于血虚等具有有良好的作用。
本发明公开了以一种人参补血剂的制备及其在贫血等血虚证的治疗方面的作用。
实验例1 人参补血剂的药效学研究
人参补血剂主要由人参、熟地黄、枸杞和蜂蜜组成的复方制剂，临床用于治疗阴虚血虚，并且具有滋补强壮作用，其药理作用观察，报告如下：
一、实验材料和仪器
药物：人参补血剂、人参蜂王浆自制，乙酰苯肼（化学纯），北京化工厂，四氧嘧啶，Fluka。动物：昆明种小鼠，体重18-22g或24-30g; Wistar系大鼠180-250g均购自白求恩医科大学。
仪器：721分光光度计，LD 5-2A 低速离心机。
统计学处理采用组间t检验。
二、方法与结果
人参补血剂对血虚动物的影响
59只雄性大鼠，190-250g, 分成6组，各组按表2剂量连续灌胃给药13天。自给药第7天起，除正常对照组以外，各组均皮下注射2%乙酰苯肼生理盐水10ml/kg，4天后造成血虚病理模型，剪尾取血测RBC、WBC、Hb，网织红细胞，海氏小体，人参补血剂对血虚动物的影响结果见表1。
由表1可见，人参补血剂6g /kg能够升高2%乙酰苯肼所致血虚大鼠的RBC、WBC、Hb，网织红细胞，并降低海氏小体数目，表明其对血虚具有明显的改善作用，具有滋阴补血的作用。
表 1人参补血剂对血虚动物的影响
1正常对照组2血虚组 3：人参补血剂6 g /kg，4：人参补血剂4 g /kg，5：人参补血剂2 g /kg 6阳性对照组**与对照组比较具有非常显著的差异P<0.01*与对照组比较具有显著差异P<0.05
具体实施方式
实施例1 人参补血剂的制备
[处方] 熟地黄 50g
人参（去芦） 30.43g
枸杞 30g
蜂蜜 20g
[制法] 熟地黄、人参、枸杞水煎煮3次，依次为2、1、1小时，分次滤过，合并滤液，加热浓缩提取液，加入制颗粒剂的辅料如糖粉和糊精制颗粒，干燥，整粒，密封包装。即得。
[性状] 本品为棕褐色的颗粒状，气香，味甘。
实施例2 人参补血剂在补血作用应用
按照实施例1方法制备的人参补血剂可以做成颗粒状或者膏状或者片状，灭菌报装，应用于血虚或者贫血等症状的辅助治疗，起到保健的作用。
Claims (3)
1.本发明公开了一种人参补血剂的组方及制备方法：
[处方] 熟地黄 50g
人参（去芦） 30g
枸杞 30g
蜂蜜 20g
[制法] 熟地黄、人参、枸杞水煎煮3次，依次为30分钟到1小时，分次滤过，合并滤液，加热浓缩提取液，加入制颗粒剂的辅料如糖粉和糊精制颗粒，干燥，整粒，密封包装，即得，本品为棕褐色的颗粒状，气香，味甘。
2.根据权利要求1 ，所得人参补血剂具有治疗血虚证的作用。
3. 根据权利要求1，所得人参补血剂可应用于血虚贫血等症状的治疗及预防和辅助治疗。
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104188041A (zh) * | 2014-09-24 | 2014-12-10 | 桓仁满族自治县益仁堂中药材有限公司 | 一种人参多维颗粒 |
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|---|---|---|---|---|
| CN1947761A (zh) * | 2006-10-24 | 2007-04-18 | 王日鸿 | 一种中药保健冲剂 |
| CN101879248A (zh) * | 2010-05-21 | 2010-11-10 | 郭景龙 | 一种具有补血作用的药物组合物 |
| CN102406795A (zh) * | 2011-11-03 | 2012-04-11 | 铜陵市松马食品包装机械制造有限责任公司 | 一种治疗贫血的茶膏及其制备方法 |
| CN102824529A (zh) * | 2011-06-17 | 2012-12-19 | 刘杏利 | 一种滋阴壮阳、益气生血、延年益寿的中药 |
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- 2013-11-16 CN CN201310569982.1A patent/CN103689564A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1947761A (zh) * | 2006-10-24 | 2007-04-18 | 王日鸿 | 一种中药保健冲剂 |
| CN101879248A (zh) * | 2010-05-21 | 2010-11-10 | 郭景龙 | 一种具有补血作用的药物组合物 |
| CN102824529A (zh) * | 2011-06-17 | 2012-12-19 | 刘杏利 | 一种滋阴壮阳、益气生血、延年益寿的中药 |
| CN102406795A (zh) * | 2011-11-03 | 2012-04-11 | 铜陵市松马食品包装机械制造有限责任公司 | 一种治疗贫血的茶膏及其制备方法 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104188041A (zh) * | 2014-09-24 | 2014-12-10 | 桓仁满族自治县益仁堂中药材有限公司 | 一种人参多维颗粒 |
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