CN103651427B - Mosquito-repelling emulsified oil as well as mosquito-repelling summer sleeping mat and preparation methods thereof - Google Patents
Mosquito-repelling emulsified oil as well as mosquito-repelling summer sleeping mat and preparation methods thereof Download PDFInfo
- Publication number
- CN103651427B CN103651427B CN201210356739.7A CN201210356739A CN103651427B CN 103651427 B CN103651427 B CN 103651427B CN 201210356739 A CN201210356739 A CN 201210356739A CN 103651427 B CN103651427 B CN 103651427B
- Authority
- CN
- China
- Prior art keywords
- mosquito
- repelling
- summer sleeping
- sleeping mat
- missible oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 241000255925 Diptera Species 0.000 claims abstract description 47
- MMCQRJPAMIHLQX-ZOWXZIJZSA-N Sophoramine Chemical compound C1CC[C@H]2CN3C(=O)C=CC=C3[C@@H]3[C@H]2N1CCC3 MMCQRJPAMIHLQX-ZOWXZIJZSA-N 0.000 claims abstract description 29
- 238000004043 dyeing Methods 0.000 claims abstract description 20
- 239000003960 organic solvent Substances 0.000 claims abstract description 16
- MMCQRJPAMIHLQX-UHFFFAOYSA-N Isosophoromine Natural products C1CCC2CN3C(=O)C=CC=C3C3C2N1CCC3 MMCQRJPAMIHLQX-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 13
- 239000000077 insect repellent Substances 0.000 claims description 45
- 239000007788 liquid Substances 0.000 claims description 18
- MMOXZBCLCQITDF-UHFFFAOYSA-N N,N-diethyl-m-toluamide Chemical compound CCN(CC)C(=O)C1=CC=CC(C)=C1 MMOXZBCLCQITDF-UHFFFAOYSA-N 0.000 claims description 17
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 12
- ZNQVEEAIQZEUHB-UHFFFAOYSA-N 2-ethoxyethanol Chemical compound CCOCCO ZNQVEEAIQZEUHB-UHFFFAOYSA-N 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 10
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 9
- 210000000481 breast Anatomy 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 239000001397 quillaja saponaria molina bark Substances 0.000 claims description 7
- 229930182490 saponin Natural products 0.000 claims description 7
- 150000007949 saponins Chemical class 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 claims description 3
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 claims description 3
- YKYONYBAUNKHLG-UHFFFAOYSA-N n-Propyl acetate Natural products CCCOC(C)=O YKYONYBAUNKHLG-UHFFFAOYSA-N 0.000 claims description 3
- 229940090181 propyl acetate Drugs 0.000 claims description 3
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 4
- 230000001846 repelling effect Effects 0.000 abstract description 4
- 241000238631 Hexapoda Species 0.000 abstract description 2
- 230000002045 lasting effect Effects 0.000 abstract description 2
- 206010059866 Drug resistance Diseases 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 230000009545 invasion Effects 0.000 abstract 1
- 244000144972 livestock Species 0.000 abstract 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 12
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 7
- 230000000052 comparative effect Effects 0.000 description 7
- 239000010902 straw Substances 0.000 description 7
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 5
- 210000001015 abdomen Anatomy 0.000 description 5
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 4
- 235000017491 Bambusa tulda Nutrition 0.000 description 4
- 241001330002 Bambuseae Species 0.000 description 4
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 4
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 4
- 239000011425 bamboo Substances 0.000 description 4
- 230000035617 depilation Effects 0.000 description 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- -1 Alicyclic hydrocarbon Chemical class 0.000 description 3
- 241000256113 Culicidae Species 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- BVWCFOXBDSMXEP-UHFFFAOYSA-N 1-(5-acetyl-2-methoxyphenyl)-3-methylbutan-1-one Chemical compound COC1=CC=C(C(C)=O)C=C1C(=O)CC(C)C BVWCFOXBDSMXEP-UHFFFAOYSA-N 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
- 239000004215 Carbon black (E152) Substances 0.000 description 2
- 241000144210 Culex pipiens pallens Species 0.000 description 2
- 238000012449 Kunming mouse Methods 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- OFBQJSOFQDEBGM-UHFFFAOYSA-N Pentane Chemical compound CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical class CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 description 2
- MVPPADPHJFYWMZ-UHFFFAOYSA-N chlorobenzene Chemical compound ClC1=CC=CC=C1 MVPPADPHJFYWMZ-UHFFFAOYSA-N 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 206010014599 encephalitis Diseases 0.000 description 2
- 229930195733 hydrocarbon Natural products 0.000 description 2
- 201000004792 malaria Diseases 0.000 description 2
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- WCKQPPQRFNHPRJ-UHFFFAOYSA-N 4-[[4-(dimethylamino)phenyl]diazenyl]benzoic acid Chemical compound C1=CC(N(C)C)=CC=C1N=NC1=CC=C(C(O)=O)C=C1 WCKQPPQRFNHPRJ-UHFFFAOYSA-N 0.000 description 1
- 241000256118 Aedes aegypti Species 0.000 description 1
- 241000256173 Aedes albopictus Species 0.000 description 1
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 241000256186 Anopheles <genus> Species 0.000 description 1
- 241000345998 Calamus manan Species 0.000 description 1
- 235000009024 Ceanothus sanguineus Nutrition 0.000 description 1
- 241000256054 Culex <genus> Species 0.000 description 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 1
- 208000001490 Dengue Diseases 0.000 description 1
- 206010012310 Dengue fever Diseases 0.000 description 1
- 235000009161 Espostoa lanata Nutrition 0.000 description 1
- 240000001624 Espostoa lanata Species 0.000 description 1
- 206010061217 Infestation Diseases 0.000 description 1
- 240000003553 Leptospermum scoparium Species 0.000 description 1
- 235000015459 Lycium barbarum Nutrition 0.000 description 1
- 206010027146 Melanoderma Diseases 0.000 description 1
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 description 1
- UIHCLUNTQKBZGK-UHFFFAOYSA-N Methyl isobutyl ketone Natural products CCC(C)C(C)=O UIHCLUNTQKBZGK-UHFFFAOYSA-N 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- AOILXFWEUKCKQQ-UHFFFAOYSA-N Saponin 8 Natural products COC(=O)C1(C)CCC2(CCC3(C)C(=CCC4C5(C)CCC(OC6OC(CO)C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)C(C)(C)C5CCC34C)C2C1)C(=O)OC8OC(CO)C(O)C(O)C8O AOILXFWEUKCKQQ-UHFFFAOYSA-N 0.000 description 1
- 229960000583 acetic acid Drugs 0.000 description 1
- KXKVLQRXCPHEJC-UHFFFAOYSA-N acetic acid trimethyl ester Natural products COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 description 1
- 230000000035 biogenic effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- WZWSOGGTVQXXSN-UHFFFAOYSA-N cyclohexanone;toluene Chemical compound CC1=CC=CC=C1.O=C1CCCCC1 WZWSOGGTVQXXSN-UHFFFAOYSA-N 0.000 description 1
- 208000025729 dengue disease Diseases 0.000 description 1
- 150000004816 dichlorobenzenes Chemical class 0.000 description 1
- 229960001673 diethyltoluamide Drugs 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 150000002009 diols Chemical class 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000004495 emulsifiable concentrate Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008282 halocarbons Chemical class 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 231100000518 lethal Toxicity 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229940043265 methyl isobutyl ketone Drugs 0.000 description 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 239000001294 propane Substances 0.000 description 1
- 235000012950 rattan cane Nutrition 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Catching Or Destruction (AREA)
Abstract
The invention discloses mosquito-repelling emulsified oil as well as a mosquito-repelling summer sleeping mat and preparation methods of the mosquito-repelling emulsified oil and the mosquito-repelling summer sleeping mat. The mosquito-repelling emulsified oil is composed of following components in percentage by weight: 5%-15% of deet, 2%-4% of sophoramine, 8%-15% of an emulsifying agent and the balance of an organic solvent. The mosquito-repelling summer sleeping mat is prepared by the following steps: (1) diluting the mosquito-repelling emulsified oil for 20-60 times to form a dip dyeing solution; and (2) immersing a summer sleeping mat into the dip dyeing solution and drying to prepare the mosquito-repelling summer sleeping mat. The mosquito-repelling emulsified oil provided by the invention is safe to human and livestock, is less prone to generate drug resistance and is easy to degrade in a natural environment; the prepared mosquito-repelling summer sleeping mat has strong capability of repelling the invasion of insects including mosquitoes and the like, and has a lasting mosquito-repelling effect.
Description
Technical field
The present invention relates to a kind of missible oil, summer sleeping mat and preparation method thereof, particularly relate to mosquito repellent missible oil, mosquito expelling summer sleeping mat and preparation method thereof.
Background technology
The main harm of mosquito spreads disease.According to the study, the disease of mosquitoes spread reaches more than kind more than 80.On earth, then do not have which kind of animal to have larger harm than mosquito to the mankind.
China can pathophorous mosquito be broadly divided into three classes: a class anopheles, popular name malarial mosquito, main propagation malaria.According to incompletely statistics, in 1 year of nineteen twenty-nine, the whole world is because suffering from about 2,000,000 lethal people of malaria.Another kind ofly cry culex, main propagation filariosis and Japanese Type-B encephalitis.3rd class, yellow-fever mosquito, has black and white speckle with it, cries again blackspot mosquito, main propagation Japanese Type-B encephalitis and dengue fever.
For a long time, people use multiple method to control mosquito, but effect is unsatisfactory.
Summary of the invention
For above shortcomings in prior art, one of technical problem to be solved by this invention provides a kind of mosquito repellent missible oil.
Two of technical problem to be solved by this invention is to provide a kind of preparation method of mosquito expelling summer sleeping mat.
Three of technical problem to be solved by this invention provides a kind of mosquito expelling summer sleeping mat.
The present invention seeks to be achieved through the following technical solutions:
A kind of mosquito repellent missible oil, be made up of following compositions in weight percentage: Metadelphene 5-15%, sophoramine 2-4%, emulsifier 8-15%, surplus is organic solvent.
Described emulsifier is one in Tea Saponin and agriculture breast 2201 or its mixture.Optimum, described emulsifier is mixed by 20-40wt% Tea Saponin and 60-80wt% agriculture breast 2201.
Described organic solvent can be arene: benzene,toluene,xylene; Fat hydrocarbon: pentane, hexane, octane; Alicyclic hydrocarbon type: cyclohexane, cyclohexanone, toluene cyclohexanone; Halogenated hydrocarbons: chlorobenzene, dichloro-benzenes, carrene; Alcohols: methyl alcohol, ethanol, isopropyl alcohol; Ethers: ether, expoxy propane; Ester class: methyl acetate, ethyl acetate, propyl acetate; Ketone: acetone, espeleton, methylisobutylketone, 1-METHYLPYRROLIDONE; Diol, derivatives: glycol monoethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether; Other: acetonitrile, pyridine, phenol, dimethyl sulfoxide (DMSO).
Preferably, described organic solvent is one in 1-METHYLPYRROLIDONE, ethyl acetate, propyl acetate, dimethyl sulfoxide (DMSO), glycol monoethyl ether, ethylene glycol monoethyl ether and ethylene glycol monobutyl ether or its mixture.
Optimum, described organic solvent is ethylene glycol monoethyl ether.
Metadelphene, has another name called N, N-n,N-diethyl meta-toluamide, CAS accession number: 134-62-3, English name: N, N-Diethyl-3-methylbenzamide, is called for short: DEET.
Sophoramine, English name: Sophoramine, CAS accession number: 6882-66-2.Its molecular structural formula, as follows:
Tea Saponin has another name called TS, and being by the class candy glucoside compound extracted in tea tree seed, is a kind of natural surfactant of good performance.Belong to triterpenes saponin, there is toil pungent, nasal membrane is stimulated to cause sneeze, sterling is fine white column crystal, hygroscopicity is strong, and paramethyl red, in acid, is insoluble in absolute methanol, ethanol, be insoluble to the organic solvents such as ether, acetone, benzene, benzinum, be soluble in aqueous methanol, hydrous ethanol and glacial acetic acid, aceticanhydride, pyridine etc.
The missible oil preparation method that above-mentioned mosquito repellent missible oil can adopt the industry general is prepared, concrete, following step can be adopted: add in organic solvent by Metadelphene, sophoramine and emulsifier, be heated to 50-60 DEG C, be uniformly mixed, mosquito repellent missible oil of the present invention can be obtained.
Mosquito repellent missible oil of the present invention, can spraying after dilution, can mosquito repellent rapidly.
Present invention also offers a kind of preparation method of mosquito expelling summer sleeping mat, comprise the steps:
(1) by described mosquito repellent missible oil dilute with water 20-60 doubly after, form dip dyeing liquid for shell;
(2) summer sleeping mat is contaminated in described dip dyeing liquid for shell, dry, mosquito expelling summer sleeping mat of the present invention can be obtained.
Preferably, the mass ratio of described summer sleeping mat and dip dyeing liquid for shell is 1:15-1:30, and contaminating temperature is 50 ~ 90 DEG C, immerged time 10 ~ 60min.
Obviously, in the present invention, summer sleeping mat used can be the commercially available summer sleeping mat without mosquito repellent process, as bamboo mat, numb seat, straw mat or rattan seat.
Further, present invention also offers a kind of mosquito expelling summer sleeping mat, adopt said method to be prepared from.
Mosquito expelling summer sleeping mat prepared by the present invention, the insect infestations abilities such as mosquito expelling are strong, and repelling effect is lasting, mosquito repellent missible oil to person poultry safety, not easily develop immunity to drugs, in natural environment, be easy to degraded.
Embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1: preparation mosquito repellent missible oil
Take each component by embodiment 1 data corresponding to table 1, Metadelphene, sophoramine and emulsifier are added in organic solvent, is heated to 50-60 DEG C, be uniformly mixed, mosquito repellent missible oil of the present invention can be obtained.
Table 1: mosquito repellent emulsifiable concentrate formulation list position: kilogram
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Comparative example 1 | |
| Metadelphene | 5 | 15 | 10 | 10 | 10 | 13 |
| Sophoramine | 4 | 2 | 3 | 3 | 3 | / |
| Tea Saponin | 8 | / | 10 | / | 3 | / |
| Agriculture breast 2201 | / | 15 | / | 10 | 7 | 10 |
| Ethylene glycol monoethyl ether | 83 | 68 | 77 | 77 | 77 | 77 |
Embodiment 2: preparation mosquito repellent missible oil
Take each component by embodiment 2 data corresponding to table 1, Metadelphene, sophoramine and emulsifier are added in organic solvent, is heated to 50-60 DEG C, be uniformly mixed, mosquito repellent missible oil of the present invention can be obtained.
Embodiment 3: preparation mosquito repellent missible oil
Take each component by embodiment 3 data corresponding to table 1, Metadelphene, sophoramine and emulsifier are added in organic solvent, is heated to 50-60 DEG C, be uniformly mixed, mosquito repellent missible oil of the present invention can be obtained.
Embodiment 4: preparation mosquito repellent missible oil
Take each component by embodiment 4 data corresponding to table 1, Metadelphene, sophoramine and emulsifier are added in organic solvent, is heated to 50-60 DEG C, be uniformly mixed, mosquito repellent missible oil of the present invention can be obtained.
Embodiment 5: preparation mosquito repellent missible oil
Take each component by embodiment 5 data corresponding to table 1, Metadelphene, sophoramine and emulsifier are added in organic solvent, is heated to 50-60 DEG C, be uniformly mixed, mosquito repellent missible oil of the present invention can be obtained.
Comparative example 1 prepares mosquito repellent missible oil
Take each component by comparative example 1 data corresponding to table 1, Metadelphene, agriculture breast 2201 are added in organic solvent ethylene glycol monoethyl ether, is heated to 50-60 DEG C, is uniformly mixed, mosquito repellent missible oil can be obtained.
Test case 1:
Reference literature method carries out testing (National Standard of the People's Republic of China, indoor harmacological effect evaluation repellant (GB/T17322.10 1) of agriculture chemical registration hygienic insecticide, 1998; Dong Guifan etc.
Attack is tested: growing × and wide × high for putting into the female mosquito of aedes albopictus that 300 4-5 ages in days are not sucked blood in the mosquito cage of 40cm × 30cm × 30cm.By kunming mice belly upward fixing limbs on plank.Clean belly with suds, hair remover is coated in mouse web portion, wipe with paper handkerchief after 5min, clean with tap water, dry with cotton balls.The depilation time should be not long, otherwise can destroy the skin of mouse.Draw the area of 2cm × 2cm at mouse skin depilation position, expose 4cm
2area, all the other positions are tightly covered.Examination mouse is put into mosquito cage 2min, the examination worm coming to stop to fall is that attack is qualified more than 20 persons, and this mouse and this cage mosquito can be used for repellency test.
Animal experiment: by kunming mice belly fixing limbs upward, with preceding method process mouse.
At mouse skin depilation position (2cm × 2cm), with 5 μ L/cm
2uniform application mosquito repellent missible oil of the present invention; after examination mouse is put into mosquito cage (having 300 female mosquitos); observe 2min; record thorn stings mosquito number; observing whether have bite by mosquitos at interval of putting into mosquito cage, observing 8h altogether, observing 2min at every turn; calculate effective protecting time, to there being this period of time of first bite by mosquitos to be effective protecting time from coating.Each process establishes 3 mouse to repeat, and calculates average effective guard time, Effective Vate of Protection (computing formula is as follows).And establish untreated mouse to make blank, observe the attacking ability of mosquito.
Effective Vate of Protection (%)=(contrast mosquito thorn sting number-be coated with mosquito repellent missible oil after mosquito thorn sting number)/contrast mosquito thorn stings number.
By the mosquito repellent missible oil of embodiment 1-5 and comparative example 1, adopt above-mentioned method of testing to test respectively, concrete test data is in table 2.
Table 2: repelling effect tables of data
By comparing embodiment 4 and comparative example 1, following conclusion can be drawn: sophoramine and the composite use of Metadelphene, can effectively improve mosquito repellent ability, there is synergistic effect.Biogenic is added in mosquito repellent missible oil---sophoramine, can the addition of effective Substitute For Partial Metadelphene, environmental protection more.
By comparing embodiment 5 and embodiment 3,4, following conclusion can be drawn: the composite use of Tea Saponin and agriculture breast 2201, has fabulous synergistic effect to Metadelphene and sophoramine, can effective mosquito repellent lastingly.
The preparation method of embodiment 6 mosquito expelling summer sleeping mat
(1) by after mosquito repellent missible oil dilute with water 60 times, dip dyeing liquid for shell is formed,
(2) contaminated in described dip dyeing liquid for shell by commercially available bamboo mat, the quality of described dip dyeing liquid for shell is 15 times of bamboo mat, and contaminating temperature is 70 DEG C, immerged time 40min.
(3) dry 3 minutes at 100 DEG C, cure 40 seconds at 115 DEG C, mosquito expelling summer sleeping mat of the present invention can be obtained.
The present embodiment adopts the mosquito repellent missible oil prepared by embodiment 1.
The preparation method of embodiment 7 mosquito expelling summer sleeping mat
(1) dip dyeing liquid for shell is formed by after mosquito repellent missible oil dilute with water 20 times,
(2) contaminated in described dip dyeing liquid for shell by commercially available straw mat, the quality of described dip dyeing liquid for shell is 15 times of bamboo mat, and contaminating temperature is 80 DEG C, immerged time 50min.
(3) dry 3 minutes at 80 DEG C, cure 40 seconds at 125 DEG C, mosquito expelling summer sleeping mat of the present invention can be obtained.
The present embodiment adopts the mosquito repellent missible oil prepared by embodiment 2.
The preparation method of embodiment 8 mosquito expelling summer sleeping mat
(1) by after mosquito repellent missible oil dilute with water 40 times, dip dyeing liquid for shell is formed,
(2) contaminated in described dip dyeing liquid for shell by commercially available straw mat, the quality of described dip dyeing liquid for shell is 20 times of commercially available straw mat, and contaminating temperature is 80 DEG C, immerged time 50min.
(3) dry 3 minutes at 90 DEG C, cure 40 seconds at 120 DEG C, mosquito expelling summer sleeping mat of the present invention can be obtained.
The present embodiment adopts the mosquito repellent missible oil prepared by embodiment 5.
The preparation method of comparative example 2 mosquito expelling summer sleeping mat
(1) dip dyeing liquid for shell is formed by after mosquito repellent missible oil dilute with water 40 times,
(2) contaminated in described dip dyeing liquid for shell by commercially available straw mat, the quality of described dip dyeing liquid for shell is 20 times of commercially available straw mat, and contaminating temperature is 80 DEG C, immerged time 50min.
(3) dry 3 minutes at 90 DEG C, cure 40 seconds at 120 DEG C, mosquito expelling summer sleeping mat of the present invention can be obtained.
The present embodiment adopts the mosquito repellent missible oil prepared by comparative example 1.
Test case 2:
(1) processing sample: mosquito expelling summer sleeping mat is cut into 15cm × 8cm.
(2) prepare examination worm: mosquito is put into plate with after ether light anesthesia, and is placed on ice cube, select the female mosquito of Culex pipiens pallens, every 50 are one group and put into mosquito cage.
(3) observing effect: after small white mouse being fixed belly depilation, overlay on belly by processing sample, and by plastic wraps, expose 2cm × 4cm area, be treated to contrast equally with untreated samples.In temperature control laboratory, examination mouse is put into cage, observe the mosquito number that Culex pipiens pallens 15min stops to fall on sample.
(4) data processing: calculate mosquito and stop the frequency (on average every mosquito stops the number of times that falls) that falls.
Table 3: the repelling effect table of mosquito expelling summer sleeping mat
Blank example, refers to the commercially available straw mat without any mosquito repellent process, directly adopts the method for test case 2 to test.
Claims (8)
1. a mosquito repellent missible oil, is characterized in that, is made up of following compositions in weight percentage: Metadelphene 5-15%, sophoramine 2-4%, emulsifier 8-15%, and surplus is organic solvent.
2. mosquito repellent missible oil as claimed in claim 1, is characterized in that: described emulsifier is one in Tea Saponin and agriculture breast 2201 or its mixture.
3. mosquito repellent missible oil as claimed in claim 2, is characterized in that: described emulsifier is mixed by 20-40wt% Tea Saponin and 60-80wt% agriculture breast 2201.
4. mosquito repellent missible oil as claimed in claim 1, is characterized in that: described organic solvent is one in 1-METHYLPYRROLIDONE, ethyl acetate, propyl acetate, dimethyl sulfoxide (DMSO), glycol monoethyl ether, ethylene glycol monoethyl ether and ethylene glycol monobutyl ether or its mixture.
5. mosquito repellent missible oil as claimed in claim 4, is characterized in that: described organic solvent is ethylene glycol monoethyl ether.
6. a preparation method for mosquito expelling summer sleeping mat, is characterized in that, comprises the steps:
(1) by the mosquito repellent missible oil dilute with water 20-60 described in any one of claim 1-5 doubly after, form dip dyeing liquid for shell;
(2) summer sleeping mat is contaminated in described dip dyeing liquid for shell, dry.
7. the preparation method of mosquito expelling summer sleeping mat as claimed in claim 6, is characterized in that: the mass ratio of described summer sleeping mat and dip dyeing liquid for shell is 1:15-1:30, and contaminating temperature is 50 ~ 90 DEG C, immerged time 10 ~ 60min.
8. a mosquito expelling summer sleeping mat, is characterized in that: adopt the method described in claim 6 or 7 to be prepared from.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410836576.1A CN104522001B (en) | 2012-09-21 | 2012-09-21 | Mosquito expelling summer sleeping mat |
| CN201210356739.7A CN103651427B (en) | 2012-09-21 | 2012-09-21 | Mosquito-repelling emulsified oil as well as mosquito-repelling summer sleeping mat and preparation methods thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210356739.7A CN103651427B (en) | 2012-09-21 | 2012-09-21 | Mosquito-repelling emulsified oil as well as mosquito-repelling summer sleeping mat and preparation methods thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410836576.1A Division CN104522001B (en) | 2012-09-21 | 2012-09-21 | Mosquito expelling summer sleeping mat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103651427A CN103651427A (en) | 2014-03-26 |
| CN103651427B true CN103651427B (en) | 2015-02-11 |
Family
ID=50291143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210356739.7A Active CN103651427B (en) | 2012-09-21 | 2012-09-21 | Mosquito-repelling emulsified oil as well as mosquito-repelling summer sleeping mat and preparation methods thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103651427B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103932542B (en) * | 2014-04-17 | 2015-11-25 | 宁波东方席业有限公司 | A kind of expelling parasite mat |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1180074A (en) * | 1997-02-18 | 1998-04-29 | 山东农业大学 | Extraction of sophora alopecuroides extract and its composition |
| CN201630808U (en) * | 2010-04-10 | 2010-11-17 | 励金友 | Summer sleeping mat coated with mosquito repellent layer |
-
2012
- 2012-09-21 CN CN201210356739.7A patent/CN103651427B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1180074A (en) * | 1997-02-18 | 1998-04-29 | 山东农业大学 | Extraction of sophora alopecuroides extract and its composition |
| CN201630808U (en) * | 2010-04-10 | 2010-11-17 | 励金友 | Summer sleeping mat coated with mosquito repellent layer |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103651427A (en) | 2014-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103651634B (en) | Citronella oil mosquito expelling liquid, mosquito expelling summer sleeping mat and preparation method thereof | |
| CN103371171B (en) | Biogenic emulsifiable insecticide and method for preparing same | |
| CN1382375A (en) | Pediculus and nit killing compsns. and method for killing head pediculus and its nit | |
| CN101780020B (en) | Cool and refreshing toilet water capable of relieving itching and expelling mosquito | |
| CN103651600B (en) | Mentha piperita oil mosquito expelling liquid, mosquito expelling summer sleeping mat and preparation method thereof | |
| CN104480706B (en) | Biogenic Mothproof fabric | |
| CN103651427B (en) | Mosquito-repelling emulsified oil as well as mosquito-repelling summer sleeping mat and preparation methods thereof | |
| CN101133741A (en) | Vermins-expelling vermins-proof disinfection preparations for fabric | |
| CN101173485A (en) | Vermins-proof preparations for fabric | |
| CN103371169B (en) | Sophoramine insect-preventing missible oil, sophoramine insect-preventing fabric and preparation method of fabric | |
| CN101697732A (en) | Sanitary pesticide composite | |
| CN114767579A (en) | Mosquito repellent liquid with slow release effect and preparation method thereof | |
| CN104522001B (en) | Mosquito expelling summer sleeping mat | |
| CN109937035A (en) | Antiparasitic composition and method | |
| US20180049433A1 (en) | Semiochemical compositions for the prevention of hematophagous diptera insects from landing and biting animals | |
| Dunford et al. | Determination of insecticidal effect (LCD50 and LCD90) of organic fatty acids mixture (C8910+ silicone) against malaria vectors | |
| CN103397520B (en) | Fabric desinsection mosquito-repellent anti-static biologic product | |
| Widawati et al. | Study of Herbal Topical Repellent Made of Betel Leaves (Piper betle) and Patchouli Oil (Pogostemon cablin) Mixture Against Yellow Fever Mosquito (Aedes aegypti) | |
| CN104488983A (en) | Application of eucalyptus globulus labill leaf essential oil | |
| CN108991032A (en) | A kind of fly-killing agent and the preparation method and application thereof | |
| CN103749530B (en) | A kind of Pesticidal combination containing Avermectin | |
| CN105454259A (en) | Insecticidal combination containing o-phenylenediamine insecticide and abamectin | |
| CN108200912A (en) | Mosquito repellent missible oil, mosquito expelling summer sleeping mat and preparation method thereof | |
| CN106808541A (en) | Mosquito expelling summer sleeping mat | |
| Hussain et al. | Mosquito repellant activity of extracts of Chandana and Sarshapa |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent of invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Jie Inventor after: Meng Fan Inventor after: Zhao Jie Inventor before: Song Guoxin Inventor before: Huang Yi |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: SONG GUOXIN HUANG YI TO: WANG JIE MENG FAN ZHAO JIE |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20180830 Address after: 233000 Yuyue District, 1750 Yuen Hui Road, Bengbu, Anhui, 309 Patentee after: Anhui Xuan Rui patent assessment technology Co.,Ltd. Address before: 200137 1F79 14, 528 Yang Gao Bei Road, Pudong New Area, Shanghai. Patentee before: SHANGHAI TAOHONG CHEMICAL TECHNOLOGY Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190531 Address after: Room 106, C2-2 Building, Linyi Mall, Fuyang City, Anhui Province, 99 Yingdong Road, Zhouping Office, Yingquan District, Fuyang City, 236000 Patentee after: Fuyang Chuangqi Crafts Co.,Ltd. Address before: 233000 Yuyue District, 1750 Yuen Hui Road, Bengbu, Anhui, 309 Patentee before: Anhui Xuan Rui patent assessment technology Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20230809 Address after: 236000 No.13, dingda Road, industrial park, Yingquan District, Fuyang City, Anhui Province Patentee after: ANHUI HUIYI COMMUNICATION SCIENCE Co.,Ltd. Address before: Room 23699, Yingpeng Road, Fuyang City, Anhui Province Patentee before: Fuyang Chuangqi Crafts Co.,Ltd. |