CN103623182B - Medicine for treating gynecological inflammations and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating gynecological inflammations and a preparation method thereof. The medicine is prepared from the following medicinal materials by weight: 5 to 20 parts of bone fossil of big mammals, 5 to 20 parts of Gorgon fruit, 3 to 10 parts of honeysuckle flower, 5 to 20 parts of dandelion, 3 to 10 parts of menthol, 3 to 10 parts of gingko, 5 to 20 parts of oyster, 5 to 20 parts of patrinia herb, 3 to 15 parts of wolfberry, 3 to 15 parts of white peony root, 3 to 15 parts of root of large-flowered skullcap, 5 to 20 parts of safflower, 3 to 15 parts of motherwort, 3 to 10 parts of spatholobus stem, 3 to 10 parts of Cherokee rose root, 3 to 10 parts of weeping forsythia capsule, 3 to 10 parts of aloe, 3 to 15 parts of Sichuan lovage rhizome and 5 to 20 parts of Chinese angelica. The medicine provided by the invention uses herbaceous plants as raw materials, has small toxic and side effects and is powder; the medicine is externally applied, can be rapidly dissolved and absorbed and has good anti-inflammation and sterilization effects and fast action.

Description

A kind of medicine for the treatment of gynecological inflammation and preparation method thereof

Technical field

The present invention relates to pharmaceutical formulation field, be specifically related to a kind of medicine for the treatment of gynecological inflammation and preparation method thereof.

Background technology

Gynecological inflammation refers to that female reproductive system infects caused disease, the adult female in the whole world approximately 87% infection in various degree gynecological inflammation, clinical common gynecological inflammation has vaginitis, cervicitis, pelvic inflammatory disease, endometritis, adnexitis etc., often prolongedly do not heal, affect quality of life and love life, and can cause infertile, induced tumor etc., have endless trouble.Due to common, frequently-occurring disease that the particularity gynecological inflammation of female sex organ is adult female, its clinical manifestation is varied, and the cause of disease is complicated and often with severe complication what time, and women's live and work is brought to very large impact.Very large to women's health harm.Although the method for the treatment of gynecological inflammation is a lot of at present, all cannot fundamentally treat, and without special efficacy, and has certain side effect.

Summary of the invention

Object of the present invention provides the one can be effective fast, and the medicine of the treatment gynecological inflammation having no side effect and preparation method thereof.

For achieving the above object, the present invention adopts following technical scheme:

A kind of medicine for the treatment of gynecological inflammation and preparation method thereof, it is formulated by the drug material of following parts by weight, Os Draconis 5-20 part, Semen Euryales 5-20 part, Flos Lonicerae 3-10 part, Herba Taraxaci 5-20 part, menthol 3-10 part, Semen Ginkgo 3-10 part, Concha Ostreae 5-20 part, Herba Patriniae 5-20 part, Fructus Lycii 3-15 part, Radix Paeoniae Alba 3-15 part, Radix Scutellariae 3-15 part, Flos Carthami 5-20 part, Herba Leonuri 3-15 part, Caulis Spatholobi 3-10 part, Radix Rosae Laevigatae 3-10 part, Fructus Forsythiae 3-10 part, Aloe 3-10 part, Rhizoma Chuanxiong 3-15 part, Radix Angelicae Sinensis 5-20 part;

Its preparation method is: (by weight)

Step 1: fetch water 82 parts, 4 parts of glycerol, xanthan gum 1 part (after dissolving in advance) are mixed and heated to 80 degree, sterilizing;

Step 2: get 4 parts of emulsifying agents, 3 points of spermaceti stearyl alcohols, 2 parts of squalanes, 2 parts of Palmic acid isooctyls, 2 parts, sad certain herbaceous plants with big flowers acid glycerol three fat, is mixed and heated to 80 degree, sterilizing;

Step 3: by step 1 gained solution and the homogeneous 30-35 minute of step 2 gained solution mixing constant temperature to 80 degree;

Step 4: step 3 gained solution is cooled to 60 degree, heats the Azelaic Acid of 1 part, stir and continue cooling, be cooled to below 50 degree;

Step 5: get 5 parts of Os Draconis, 5 parts of Semen Euryaless, 5 parts of Flos Loniceraes, 10 parts of Herba Taraxacis, 5 parts of menthols, 3 parts of Semen Ginkgoes, 10 parts of Concha Ostreaes, 5 parts of Herba Patriniae, 4 parts of Fructus Lycii, 6 parts of the Radix Paeoniae Albas, 3 parts of Radix Scutellariaes, 10 parts, Flos Carthami, 4 parts of Herba Leonuris, 3 parts of Caulis Spatholobis, 3 parts of Radix Rosae Laevigataes, 3 parts of Fructus Forsythiaes, 3 parts of Aloes, 4 parts of Rhizoma Chuanxiongs, 9 parts of Radix Angelicae Sinensis, be positioned in marmite, in marmite, add the water that at least can flood medical material, first with big fire by after water boil in marmite, use low baking temperature instead and decoct 0.5-2 hour, obtain decoction;

Step 6: step 4 gained solution is mixed with step 5 gained decoction, continue to stir, be cooled to 38 degree and stop stirring;

Step 7: by air-dry step 6 gained solution, inspection, fill, gets product.

Effect of each taste medicine and effect:

Flos Carthami: warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.

Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.

The Radix Paeoniae Alba: its bitter in the mouth, acid, is slightly cold.Return Liver Channel.There is suppressing liver-YANG, nourish blood and receive effect of the moon.Cure mainly feeling of fullness in the head, headache, dizzy, tinnitus, irritated irritability, menoxenia, dysmenorrhea, metrorrhagia, spontaneous perspiration, night sweat, pain in chest and hypochondrium, carpopedal spasm pain.

Flos Lonicerae: the sweet cold fragrance of property.Heat-clearing and toxic substances removing, wind-heat dissipating.For carbuncle furuncle, sore throat, erysipelas, warm blood fulminant dysentery, anemopyretic cold, epidemic febrile disease heating.

Rhizoma Chuanxiong: medicine first choice for the treatment of headache.Menoxenia; Amenorrhea dysmenorrhea; The stagnant raw meat pain of the stasis of blood in puerperal; Lump in the abdomen lump; Pain in chest and hypochondrium; Have a headache dizzy; Anemofrigid-damp arthralgia; Traumatic injury; Ulcer sores.

Fructus Forsythiae: hardship, cool.Enter the heart, liver, gallbladder meridian.Function cures mainly: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.

Os Draconis: sweet puckery; Flat; Nontoxic.The heart; Liver; Kidney; Large intestine channel.Function cures mainly: tranquillizing the mind by relieving convulsion; Suppressing the hyperactive liver and subsiding YANG; Astringent or styptic treatment for spontaneous sweating; Convergence.Main infantile convulsion is demented; Severe palpitation; Insomnia forgetfulness; Have a dizzy spell; Spontaneous sweating; The seminal emission enuresis; Bleeding not during menses; Chronic diarrhea chronic dysentery; Ulcer does not close up and eczema for a long time.

Semen Euryales: sweet in the mouth, property is flat.Return spleen, lung, kidney channel.Effect: reinforcing the kindey to control nocturnal emission, spleen reinforcing stopping leak, promoting diuresis to eliminate damp pathogen.Control seminal emission, stranguria with turbid discharge, leukorrhagia, incontinence of urine, has loose bowels, dysentery, damp arthralgia

Semen Ginkgo: property is flat, sweet in the mouth bitterness is slightly poisonous; Enter lung, kidney channel.Effect: the gas of astringing the lung, relieving asthma and cough, leukorrhagia stopping is turbid, urine reducing, disinfection.Cure mainly asthma, phlegmatic cough, nocturnal emission, leucorrhea, nebulousurine, infantile diarrhea, malnutrition due to parasitic infestation, hemorrhoidal hamorrhage dysentery, gonorrhea, frequent micturition, and the disease such as scabies, dermatitis rhus, white tumor wind.

Concha Ostreae: salty wet, cool.Enter liver, kidney channel.Function cures mainly: yin fluid astringing, and YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduces phlegm, softening the hard mass.Control infantile convulsion, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.The insomnia that is used for palpitating with fear, vertigo and tinnitus, tuberculous lymphadenitis, abdominal mass mass in the abdomen, spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache pantothenic acid.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.

Herba Patriniae: nature and flavor are cool in nature, acrid in the mouth, hardship.Function cures mainly: heat-clearing and toxic substances removing, removing blood stasis and expelling pus.For appendicitis, dysentery, enteritis, hepatitis, eye conjunctivitis, postnatal blood stasis stomachache, carbuncle furuncle.

Herba Taraxaci: sweet, micro-hardship, cold.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.

Caulis Spatholobi: relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation.Main numb hand and foot; Quadriplegia; Rheumatic arthralgia; Women has through uncomfortable; Dysmenorrhea; Amenorrhea.

Radix Rosae Laevigatae: restrain astringent or styptic treatment for spontaneous sweatingly, arresting bleeding and healing up ulcer, invigorates blood circulation in dispelling, pain relieving, parasite killing.Main spermatorrhea; The enuresis; Dysentery; Have loose bowels; Hemoptysis; Have blood in stool; Metrorrhagia; Leukorrhagia; Proctoptosis; Uterine prolapse; Rheumatic arthralgia; Traumatic injury; Skin infection; Scald; Toothache; Stomachache; Ascariasis; All bones larynx of choking; Chyluria.

Aloe: under rushing down; Liver heat removing; Parasite killing.Main constipation with heat retention; Liver-fire headache; Conjunctival congestion infantile convulsion; Abdominal pain due to worm stagnation; Scabies; Hemorrhoid complicated by anal fistula; Solution Fructus Crotonis poison.For constipation, infantile malnutrition, infantile convulsion; External treatment exudative dermatitis.

Fructus Lycii: caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness of the waist and knees; Impotence and seminal emission; Cough due to consumptive disease; The taking fluids profusely of quenching one's thirst.

Menthol: there is antipruritic, pain relieving, anticorrosion, stimulation, anesthesia, refrigerant and antiinflammatory action, can control headache, neuralgia, pruritus and respiratory inflammation, atrophic rhinitis, celostomia etc.

Azelaic Acid: be externally used antimicrobial agent, various aerobe on skin and anaerobe are had to inhibition and killing action, the azelaic acid ointment of local use 20% can significantly reduce the growth of propionibacterium bacterioid in skin bacterium and folliculus, and the free fatty acid content of skin surface lipid is declined.The antibacterial activity of this product and absorption, all depend on pH, when pH is low, has higher antibacterial activity, enters quickly in cell, and the dermatosis that various different pathogenies are caused has good antibacterial action.Feature is that to be penetrated into paracytic dose more than normal cell, can reversibly suppress the activity of Major Enzymes.The same with antibacterial mechanism of action with other antibacterial, Profilin matter synthetic.This product has anti-keratinization effect to the skin of normal skin and acne infection, and its action principle is to reduce folliculus hyperkeratosis.This product also has anti-hypertrophy and anticytotoxin effect, and this is seemingly synthetic by destroying mitochondrial respiratory and cell DNA, instead of the activity of restraint of tyrosinase.Ultraviolet structural research proves, work as skin or choroidal melanoma cells in vitro or be placed in Folium Rhododendri Simsii acid solution (≤100nmol/L) from suffering from malignant lentigo or cutaneous melanoma patient's skin biopsy tissue, having the phenomenon that the obvious mitochondrion expansion of selectivity, formation cavity and endochylema lipid particles are assembled.Aspect reducing pigmentation and reducing melasma lesion size, this product of 20% is suitable with 4% hydroquinone ointment, is obviously better than 2% hydroquinone ointment.This product can significantly reduce the number of acne, pimple and pustule to the patient of light moderate acne.

The present invention herbaceous plant of drawing materials, toxic and side effects is little, and material is powder, the quick solution absorption of external, anti-inflammation and sterilization is effective, takes effect very fast.

Brief description of the drawings

Fig. 1 is process flow diagram of the present invention.

Detailed description of the invention

In order to make object of the present invention, technical scheme and advantage clearer, below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.

This detailed description of the invention is by the following technical solutions: a kind of medicine for the treatment of gynecological inflammation and preparation method thereof, it is formulated by the drug material of following parts by weight, Os Draconis 5-20 part, Semen Euryales 5-20 part, Flos Lonicerae 3-10 part, Herba Taraxaci 5-20 part, menthol 3-10 part, Semen Ginkgo 3-10 part, Concha Ostreae 5-20 part, Herba Patriniae 5-20 part, Fructus Lycii 3-15 part, Radix Paeoniae Alba 3-15 part, Radix Scutellariae 3-15 part, Flos Carthami 5-20 part, Herba Leonuri 3-15 part, Caulis Spatholobi 3-10 part, Radix Rosae Laevigatae 3-10 part, Fructus Forsythiae 3-10 part, Aloe 3-10 part, Rhizoma Chuanxiong 3-15 part, Radix Angelicae Sinensis 5-20 part,

As shown in Figure 1, its preparation method is: (by mass percentage)

Step 1: fetch water 82 parts, 4 parts of glycerol, xanthan gum 1 part (after dissolving in advance) are mixed and heated to 80 degree, sterilizing;

Step 2: get 4 parts of emulsifying agents, 3 points of spermaceti stearyl alcohols, 2 parts of squalanes, 2 parts of Palmic acid isooctyls, 2 parts, sad certain herbaceous plants with big flowers acid glycerol three fat, is mixed and heated to 80 degree, sterilizing;

Step 3: by step 1 gained solution and the homogeneous 30-35 minute of step 2 gained solution mixing constant temperature to 80 degree;

Step 4: step 3 gained solution is cooled to 60 degree, heats the Azelaic Acid of 1 part, stir and continue cooling, be cooled to below 50 degree;

Step 5: get 5 parts of Os Draconis, 5 parts of Semen Euryaless, 5 parts of Flos Loniceraes, 10 parts of Herba Taraxacis, 5 parts of menthols, 3 parts of Semen Ginkgoes, 10 parts of Concha Ostreaes, 5 parts of Herba Patriniae, 4 parts of Fructus Lycii, 6 parts of the Radix Paeoniae Albas, 3 parts of Radix Scutellariaes, 10 parts, Flos Carthami, 4 parts of Herba Leonuris, 3 parts of Caulis Spatholobis, 3 parts of Radix Rosae Laevigataes, 3 parts of Fructus Forsythiaes, 3 parts of Aloes, 4 parts of Rhizoma Chuanxiongs, 9 parts of Radix Angelicae Sinensis, be positioned in marmite, in marmite, add the water that at least can flood medical material, first with big fire by after water boil in marmite, use low baking temperature instead and decoct 0.5-2 hour, obtain decoction;

Step 6: step 4 gained solution is mixed with step 5 gained decoction, continue to stir, be cooled to 38 degree and stop stirring;

Step 7: by air-dry step 6 gained solution, inspection, fill, gets product.

In sum, the present invention herbaceous plant of drawing materials, toxic and side effects is little, and material is powder, the quick solution absorption of external, anti-inflammation and sterilization is effective, takes effect very fast.

The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (1)

1. treat the medicine of gynecological inflammation for one kind, it is characterized in that: it is formulated by the drug material of following parts by weight 5 parts of Os Draconis, 5 parts of Semen Euryaless, 5 parts of Flos Loniceraes, 10 parts of Herba Taraxacis, 5 parts of menthols, 3 parts of Semen Ginkgoes, 10 parts of Concha Ostreaes, 5 parts of Herba Patriniae, 4 parts of Fructus Lycii, 6 parts of the Radix Paeoniae Albas, 3 parts of Radix Scutellariaes, 10 parts, Flos Carthami, 4 parts of Herba Leonuris, 3 parts of Caulis Spatholobis, 3 parts of Radix Rosae Laevigataes, 3 parts of Fructus Forsythiaes, 3 parts of Aloes, 4 parts of Rhizoma Chuanxiongs, 9 parts of Radix Angelicae Sinensis;

Its preparation method is by weight:

Step 1: fetch water 82 parts, 4 parts of glycerol, 1 part of xanthan gum, after dissolving in advance, be mixed and heated to 80 degree, sterilizing;

Step 2: get 4 parts of emulsifying agents, 3 parts of spermaceti stearyl alcohols, 2 parts of squalanes, 2 parts of Palmic acid isooctyls, 2 parts, sad certain herbaceous plants with big flowers acid glycerol three fat, is mixed and heated to 80 degree, sterilizing;

Step 3: by step 1 gained solution and the homogeneous 30-35 minute of step 2 gained solution mixing constant temperature to 80 degree;

Step 4: step 3 gained solution is cooled to 60 degree, heats the Azelaic Acid of 1 part, stir and continue cooling, be cooled to below 50 degree;

Step 5: get 5 parts of Os Draconis, 5 parts of Semen Euryaless, 5 parts of Flos Loniceraes, 10 parts of Herba Taraxacis, 5 parts of menthols, 3 parts of Semen Ginkgoes, 10 parts of Concha Ostreaes, 5 parts of Herba Patriniae, 4 parts of Fructus Lycii, 6 parts of the Radix Paeoniae Albas, 3 parts of Radix Scutellariaes, 10 parts, Flos Carthami, 4 parts of Herba Leonuris, 3 parts of Caulis Spatholobis, 3 parts of Radix Rosae Laevigataes, 3 parts of Fructus Forsythiaes, 3 parts of Aloes, 4 parts of Rhizoma Chuanxiongs, 9 parts of Radix Angelicae Sinensis, be positioned in marmite, in marmite, add the water that at least can flood medical material, first with big fire by after water boil in marmite, use low baking temperature instead and decoct 0.5-2 hour, obtain decoction;

Step 6: step 4 gained solution is mixed with step 5 gained decoction, continue to stir, be cooled to 38 degree and stop stirring;

Step 7: by air-dry step 6 gained solution, inspection, fill, gets product.