CN102204977A - Preparation method and application of ointment composition for external use for treating tubal nowhere - Google Patents
Preparation method and application of ointment composition for external use for treating tubal nowhere Download PDFInfo
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- CN102204977A CN102204977A CN 201110121608 CN201110121608A CN102204977A CN 102204977 A CN102204977 A CN 102204977A CN 201110121608 CN201110121608 CN 201110121608 CN 201110121608 A CN201110121608 A CN 201110121608A CN 102204977 A CN102204977 A CN 102204977A
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Abstract
The invention relates to a traditional Chinese medicine ointment for external use, in particular to a preparation method of an ointment composition for external use for treating tubal nowhere, comprising the composition and a preparation process. The composition comprises bupleurum, immature bitter orange, red peony root, danshen root, beautiful sweetgum fruit, gleditsia thorn, Sichuan carthamus flower, epimedium, hirsute shiny bugleweed herb, Chinese clematis root, dried orange peel, trichosanthes root and Chinese angelica. The preparation process comprises the steps of: drying a sufficient amount of medicines at low temperature, mixing and pulverizing, then putting the medicinal powder into a glass container, adding vinegar, stirring the dried medicinal powder to form medicinal paste, sealing for later use; pouring the medicinal paste into a stainless steel kettle; and decocting with soft fire to obtain the ointment for external use. The ointment composition for external use belongs to a pure traditional Chinese medicine prescription for external use, and avoids the defects of poor effect and pain caused by operation in the existing therapeutic method, and the medicament can directly penetrate into the focus and is safe in clinical application.
Description
[technical field]
The present invention relates to a kind of Chinese medicine external-applied ointment, particularly a kind of external-applied ointment preparation of compositions method and application thereof for the treatment of obstruction of fallopian tube.
[background technology]
Known, salpingemphraxis is the common cause of infertility, accounts for 1/3 of infertile patient, and the trend that rises is gradually arranged in recent years, and salpingemphraxis is the treatment difficult problem of infertility.Salpingemphraxis mainly due to inflammation through endometrium to vertical spread, cause that at first the fallopian tube mucositis sexually revises, uterine tubal epithelium generation degeneration or fall in flakes cause the adhesion of fallopian tube mucosa, then fallopian tube tube chamber or the locking of umbrella portion.Traditional therapy is mainly hydrotubation or operative treatment.Though hydrotubation is simple to operate, poor accuracy, effect is dissatisfied, is eliminated by most of hospital gradually; And the fallopian tube implantation, surgery microsurgery equipment requirements height such as anastomosis or neostomy, expensive big, and uncertain therapeutic efficacy is cut aspect functional rehabilitation.
Because the fallopian tube implantation, anastomosis or neostomy need be performed the operation body internal congestion position is dredged, and Therapeutic Method effects such as the hydrotubation released of a lot of hospitals, Salpingography, laparoscopic surgery are relatively poor.Wherein success rate height in the operation of laparoscopic surgery is for the control of inflammation, comparatively difficult after still performing the operation, and because the stimulation of inflammation can produce the hydrops adhesion once more, obstruction; Caused the secondary misery of sufferer.
[summary of the invention]
In order to overcome the deficiency in the background technology, the invention discloses a kind of external-applied ointment preparation of compositions method and application thereof for the treatment of obstruction of fallopian tube, the present invention mainly is made of Radix Bupleuri, Fructus Aurantii Immaturus, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Fructus Liquidambaris, Spina Gleditsiae, Flos Carthami, Herba Epimedii, Herba Lycopi, Radix Clematidis, Pericarpium Citri Reticulatae, Radix Trichosanthis and Radix Angelicae Sinensis, belong to pure Chinese medicine external prescription, avoided weak effect and the painful drawback of operation in the existing Therapeutic Method, can make medicine directly permeate the arrival focus; Clinical practice safety.
In order to realize the purpose of described invention, the present invention adopts following technical scheme:
A kind of external-applied ointment preparation of compositions method for the treatment of obstruction of fallopian tube comprises to become to be grouped into and preparation technology; Wherein composition consists of " according to weight ratio ", comprises following composition:
Ointment composition preparation method of the present invention is as follows:
A, get capacity Radix Bupleuri, Fructus Aurantii Immaturus, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Fructus Liquidambaris, Spina Gleditsiae, Flos Carthami, Herba Epimedii, Herba Lycopi, Radix Clematidis, Pericarpium Citri Reticulatae, Radix Trichosanthis and Radix Angelicae Sinensis and be placed in the oven drying at low temperature ozone disinfection cabinet oven dry 40 to 80 minutes, dry drug;
B, the rapid dry drug of previous step put into ultrafine crusher mix to pulverize, smashing fineness 20～60, dry medicated powder;
C, the rapid dry medicated powder of previous step is placed in the glass container, adding vinegar and stirring makes dry medicated powder form mass, mass is advisable can trickle into line, left standstill 20 minutes, on pasty state medicated powder, add a spot of vinegar once more, make vinegar flood pasty state medicated powder fully and be advisable, then with seal of vessel, temperature is controlled between 20～30 degree and placed at least 24 hours, and is stand-by;
D, the rapid mass of previous step is poured in the stainless-steel pan, slow fire boiled 30 minutes at least then, stirred while enduring to make mass form the thickness state, and wherein temperature is controlled between 80～900 degree, added the Colophonium foam of pulverizing then and stirred, and formed ointment; The addition of wherein said Colophonium foam is 60～80 grams;
E, ointment is split on the coating while hot the external-applied ointment that forms the treatment obstruction of fallopian tube.
The external-applied ointment preparation of compositions method of described treatment obstruction of fallopian tube, described oven drying at low temperature ozone disinfection cabinet are the diligent equipment company limited production of sky, Hebei province.
The external-applied ointment preparation of compositions method of described treatment obstruction of fallopian tube, described ultrafine crusher are really pharmaceutical machine factory production in the Jishou City.
The external-applied ointment preparation of compositions method of described treatment obstruction of fallopian tube, vinegar are edible rice vinegar, wheat vinegar or Sorghum vulgare Pers. vinegar.
A kind of application of external-applied ointment compositions in obstruction of fallopian tube for the treatment of obstruction of fallopian tube.
The application of external-applied ointment compositions in obstruction of fallopian tube of described treatment obstruction of fallopian tube, women's menstruation began on the 13rd day that ointment was examined heat and be affixed on the affected part to 60 degree, kept three days.
The application of external-applied ointment compositions in obstruction of fallopian tube of described treatment obstruction of fallopian tube, menstruation come to begin in 6 days before that ointment is examined heat and paste three days in the affected part to 60 degree.
Beneficial effect of the present invention is:
Radix Bupleuri, Fructus Aurantii Immaturus, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Fructus Liquidambaris, Spina Gleditsiae, Flos Carthami, Herba Epimedii, Herba Lycopi, Radix Clematidis, Pericarpium Citri Reticulatae, Radix Trichosanthis and Radix Angelicae Sinensis are passed through oven drying at low temperature, can guarantee in the pulverizing of post-treatment step and can not destroy drug effect, through the hybrid medicine of pulverizing, can force that effective ingredient decomposes in vinegar in vinegar soaks, and make medicine merge mutually compatibility and for toxic disappear mutually to.
Compatibility of the present invention is according to being:
Radix Bupleuri: hardship is slightly cold; Evacuation is brought down a fever, the yang invigorating soothing liver-QI.
Fructus Aurantii Immaturus: hardship, suffering, cold; Stop in stagnant; The feeling of fullness distending pain.
Radix Paeoniae Rubra: clots absorbing, pain relieving, removing heat from blood, detumescence; Control that the stasis of blood stagnates that amenorrhea, hernia abdominal mass gather, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.
Radix Salviae Miltiorrhizae: hardship is slightly cold; Promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.
Fructus Liquidambaris: hardship, flat; Dispelling, collateral-activating, diuretic stimulates the menstrual flow.Be used for arthralgia, numbness contracture, edema distension, the few amenorrhea of breast.
Spina Gleditsiae: hot, temperature, nontoxic; System carbuncle, acute mastitis, scrofula caused by pathogenic wind malignant boil, retention of placenta, parasite killing.
Flos Carthami: promoting blood circulation to restore menstrual flow, the silt of dispelling, subside a swelling, control the pain.
Herba Epimedii: suffering, sweet, temperature; Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.
Herba Lycopi: slightly warm in nature, bitter in the mouth, suffering; Blood circulation promoting and blood stasis dispelling, line water detumescence.
Radix Clematidis: hot salty, temperature, poisonous; Gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, chills and pain of the waist and kness, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.
Pericarpium Citri Reticulatae: preventing phlegm from forming and stopping coughing, digestant effect are arranged; To dyspepsia stop amassing, dyspepsia has good therapeutic effect.
Radix Trichosanthis: sweet, little hardship is slightly cold.The calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.
Radix Angelicae Sinensis: sweet in the mouth, suffering, warm in nature.Return liver, the heart, spleen channel.
Ointment composition of the present invention is based on pathogenetic research and the Therapeutic Principle of medical science to the obstruction of fallopian tube disease, simultaneously according to the pharmaceutical research achievement, through repeated screening, natural drug for the treatment of women's obstruction of fallopian tube disperse blood stasis and dredge collateral, according to reasonably combined composition of theory of Chinese medical science and consumption, through strictness control is equipped with prepared and forms.
Main feature of the present invention:
1, ointment composition of the present invention is applicable to external.
2, the direct baking of the every obedient plaster of the present invention is heated, treat that plaster is affixed on lower abdomen fallopian tube position after softening, push with hands can cement in 20 seconds that drug effect can reach about 20 days, middle plaster is in case break away from, ointment is taken off, and baking is heated, and treats that being affixed on lower abdomen fallopian tube position after plaster softens just can, the present invention 3 days was a course of treatment, the direct corresponding focus of plaster so the present invention has made full use of the effective ingredient of medical material, improves the utilization rate of medical material.
3. the invention belongs to pure Chinese medicine preparation, avoid residual; Clinical practice safety.
[specific embodiment]
Can explain the present invention in more detail by the following examples, the present invention is not limited to the following examples; Disclose purpose of the present invention and be intended to protect all changes and improvements in the scope of the invention;
A kind of external-applied ointment preparation of compositions method for the treatment of obstruction of fallopian tube comprises to become to be grouped into and preparation technology; Wherein composition consists of " according to weight ratio ", comprises following composition:
Ointment composition preparation method of the present invention is as follows:
A, get capacity Radix Bupleuri, Fructus Aurantii Immaturus, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Fructus Liquidambaris, Spina Gleditsiae, Flos Carthami, Herba Epimedii, Herba Lycopi, Radix Clematidis, Pericarpium Citri Reticulatae, Radix Trichosanthis and Radix Angelicae Sinensis and be placed in the oven drying at low temperature ozone disinfection cabinet oven dry 40 to 80 minutes, dry drug;
B, the rapid dry drug of previous step put into ultrafine crusher mix to pulverize, smashing fineness 20～60, dry medicated powder;
C, the rapid dry medicated powder of previous step is placed in the glass container, adding vinegar and stirring makes dry medicated powder form mass, mass is advisable can trickle into line, left standstill 20 minutes, on pasty state medicated powder, add a spot of vinegar once more, make vinegar flood pasty state medicated powder fully and be advisable, then with seal of vessel, temperature is controlled between 20～30 degree and placed at least 24 hours, and is stand-by;
D, the rapid mass of previous step is poured in the stainless-steel pan, slow fire boiled 30 minutes at least then, stirred while enduring to make mass form the thickness state, and wherein temperature is controlled between 80～900 degree, added the Colophonium foam of pulverizing then and stirred, and formed ointment; The addition of wherein said Colophonium foam is 60～80 grams;
E, ointment is split on the coating while hot the external-applied ointment that forms the treatment obstruction of fallopian tube.
A kind of application of external-applied ointment compositions in obstruction of fallopian tube for the treatment of obstruction of fallopian tube.
The application of external-applied ointment compositions in obstruction of fallopian tube of described treatment obstruction of fallopian tube, women's menstruation began on the 13rd day that ointment was examined heat and be affixed on the affected part to 60 degree, kept three days.
The application of external-applied ointment compositions in obstruction of fallopian tube of described treatment obstruction of fallopian tube, menstruation come to begin in 6 days before that ointment is examined heat and paste three days in the affected part to 60 degree.
The present invention is for six times a course of treatment, can increase according to actual effect.
Clinical trial statistical table of the present invention is as follows;
| Classification | Case | Recovery from illness | Produce effects | Effectively | Invalid | Effective percentage |
| Nameless gall | 69 | 46 | 13 | 5 | 5 | 92.8％ |
Wherein going up the table criterion of therapeutical effect is judged to be: treat after three to six courses of treatment to recur in 1 year and confirm as recovery from illness; Treat after three to six courses of treatment that recurrence is produce effects in 1 year; Treating after three to six courses of treatment the state of an illness alleviates to effectively; Treat do not have after three to six courses of treatment obviously be improved as invalid.
After 69 obstruction of fallopian tube sufferers were treated three to six courses of treatment through external application medical ointment of the present invention, it was invalid to have 5 people, and total effective rate reaches 92.8%.
Wherein comparatively typical three cases further specify curative effect of the present invention after using the present invention.
Sufferer one: Liu Shuhong, woman, 31 years old, peasant.In March, 2006, in November, 2008 are successively done artificial miscarriage twice, because artificial abortion causes obstruction of fallopian tube; Use the present invention fully recovered after four courses of treatment, in December, 2009 pregnancy, and 2010 10 monthly output one sons, healthy at present.
Sufferer two: WANG XIAOYAN, woman, 36 years old, workman.Pre-marital artificial abortion three times, habitual abortion twice after marriage, and is infertile for many years then, after be diagnosed as obstruction of fallopian tube, invalid through too much tame hospital therapy, fully recover pregnancy in May, 2007,2008 2 monthly output one woman after using six courses of treatment of the present invention.
Sufferer three: Ning Tianjiao, woman, 32 years old, workman.Infertile for many years after marriage, be obstruction of fallopian tube through too much tame hospital therapy, then invalid through the logical liquid of operation, use the present invention fully recovered after six courses of treatment, pregnancy in January, 2010,2010 11 monthly output one woman, mother and daughter's health at present.
The embodiment that selects for use in this article in order to disclose purpose of the present invention currently thinks to suit, but will be appreciated that, the present invention is intended to comprise that all belong to all changes and the improvement of the interior embodiment of this design and the scope of the invention.
Claims (7)
1. an external-applied ointment preparation of compositions method for the treatment of obstruction of fallopian tube comprises to become to be grouped into and preparation technology, and it is characterized in that: wherein composition consists of " according to weight ratio ", comprises following composition:
Ointment composition preparation method of the present invention is as follows:
A, get capacity Radix Bupleuri, Fructus Aurantii Immaturus, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Fructus Liquidambaris, Spina Gleditsiae, Flos Carthami, Herba Epimedii, Herba Lycopi, Radix Clematidis, Pericarpium Citri Reticulatae, Radix Trichosanthis and Radix Angelicae Sinensis and be placed in the oven drying at low temperature ozone disinfection cabinet oven dry 40 to 80 minutes, dry drug;
B, the rapid dry drug of previous step put into ultrafine crusher mix to pulverize, smashing fineness 20～60, dry medicated powder;
C, the rapid dry medicated powder of previous step is placed in the glass container, adding vinegar and stirring makes dry medicated powder form mass, mass is advisable can trickle into line, left standstill 20 minutes, on pasty state medicated powder, add a spot of vinegar once more, make vinegar flood pasty state medicated powder fully and be advisable, then with seal of vessel, temperature is controlled between 20～30 degree and placed at least 24 hours, and is stand-by;
D, the rapid mass of previous step is poured in the stainless-steel pan, slow fire boiled 30 minutes at least then, stirred while enduring to make mass form the thickness state, and wherein temperature is controlled between 80～900 degree, added the Colophonium foam of pulverizing then and stirred, and formed ointment; The addition of wherein said Colophonium foam is 60～80 grams;
E, ointment is split on the coating while hot the external-applied ointment that forms the treatment obstruction of fallopian tube.
2. the external-applied ointment preparation of compositions method of treatment obstruction of fallopian tube according to claim 1 is characterized in that: described oven drying at low temperature ozone disinfection cabinet is the diligent equipment company limited production of sky, Hebei province.
3. the external-applied ointment preparation of compositions method of treatment obstruction of fallopian tube according to claim 1, described ultrafine crusher are really pharmaceutical machine factory production in the Jishou City.
4. the external-applied ointment preparation of compositions method of treatment obstruction of fallopian tube according to claim 1, vinegar are edible rice vinegar, wheat vinegar or Sorghum vulgare Pers. vinegar.
5. according to the described a kind of application of external-applied ointment compositions in obstruction of fallopian tube for the treatment of obstruction of fallopian tube of the arbitrary claim of claim 1～4.
6. according to the application of external-applied ointment compositions in obstruction of fallopian tube of the described treatment obstruction of fallopian tube of claim 5, it is characterized in that: women's menstruation began on the 13rd day that ointment was examined heat and be affixed on the affected part to 60 degree, kept three days.
7. according to the application of external-applied ointment compositions in obstruction of fallopian tube of the described treatment obstruction of fallopian tube of claim 5, it is characterized in that: menstruation comes to begin in 6 days before that ointment is examined heat and paste three days in the affected part to 60 degree.
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| CN2011101216086A CN102204977B (en) | 2011-05-12 | 2011-05-12 | Preparation method and application of ointment composition for external use for treating tubal nowhere |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108014299A (en) * | 2017-12-26 | 2018-05-11 | 支誉英 | A kind of external application Chinese medicine for treating fallopian tube obstruction and preparation method thereof |
| CN108042112A (en) * | 2018-01-12 | 2018-05-18 | 郑州大学第附属医院 | A kind of tubal occlusion apparatus for diagnosis and therapy |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101011553A (en) * | 2006-04-18 | 2007-08-08 | 李运乃 | Chinese traditional medicine preparation for treating female barrenness |
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2011
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101011553A (en) * | 2006-04-18 | 2007-08-08 | 李运乃 | Chinese traditional medicine preparation for treating female barrenness |
Non-Patent Citations (1)
| Title |
|---|
| 《光明中医》 20061231 孟胜喜 通管汤治疗输卵管阻塞68例疗效观察 64－65 1－7 第21卷, 第4期 2 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108014299A (en) * | 2017-12-26 | 2018-05-11 | 支誉英 | A kind of external application Chinese medicine for treating fallopian tube obstruction and preparation method thereof |
| CN108042112A (en) * | 2018-01-12 | 2018-05-18 | 郑州大学第附属医院 | A kind of tubal occlusion apparatus for diagnosis and therapy |
| CN108042112B (en) * | 2018-01-12 | 2024-02-23 | 郑州大学第一附属医院 | Oviduct blockage diagnosis and treatment device |
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| CN102204977B (en) | 2012-11-14 |
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