CN103610983B - A kind of Chinese medicine preparation for the treatment of apoplexy - Google Patents
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Abstract
The invention discloses a kind of Chinese medicine preparation for the treatment of apoplexy, belong to the field of Chinese medicines; The raw material of Chinese medicine preparation effective ingredient of the present invention consists of: the Cortex Eucommiae, Flos Albiziae, Semen Persicae, Fructus Lycii, Pheretima, Flos Carthami, Caulis et Folium piperis, Herba Cynomorii, Herba speranskiae tuberculatae, Rhizoma Corydalis, Lignum Sappan, Xue Li, Ba Ji, Folium Craibiodendri Yunnanensis, Herba Menthae and Herba Cymbopogonis Citrari; Chinese medicine preparation of the present invention have restore menstrual flow and invigorate blood circulation, vessel softening, YIN nourishing and the production of body fluid promoting, wind dispelling refreshment effect, numb limbs and tense tendons, hypertension, hemiplegia that cerebral apoplexy sequela or transient ischemic attack are caused, have a dizzy spell, insomnia and dreamful sleep etc. has good therapeutic effect, and non-relapse after healing, the present invention makes simply, taking convenience, with low cost, without any side effects.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation for the treatment of apoplexy.
Background technology
Apoplexy is common in crowd and one of disease that mortality rate is very high, patient have an attack of one's old illness last as without other anomalism, but, often just lose consciousness once outbreak patient, if have little time treatment within several minutes, die, even if existing medicine uses in time, also very easily cause the sequela such as retarded or dull-witted.From ancient times to the present, hospital and pharmacy there is no specific medicament to this disease, Patients with Stroke more than 60% has hypertension history, apoplexy is the common refractory disease of serious harm human health and life security, first of four large difficult disease that motherland's medical science is classified as " wind, consumptive disease, distension, diaphragm ", there is obvious three-hypers phenomenon.2,000,000 are reached according to the annual patient with cerebral apoplexy that occurs of statistics China, sickness rate is up to 1,20/,100,000, now survival stroke patient 7,000,000, wherein 4,500,000 patients disability and can't take care of oneself in various degree, disability rate up to 75%, the annual stroke patient dead 1,200,000 of China, must cross the patient of apoplexy, also easily recur again, often recur once, increase the weight of once; Apoplexy causes great threat to human health and life, brings considerable distress to patient, family and burden on society heavy.Therefore, fully realize the seriousness of apoplexy, improve the treatment of apoplexy and prevention level, the sickness rate reducing apoplexy, disability rate and mortality rate are the task of top priority.
At present, apoplexy Therapeutic Method has intravenously administrable, acupuncture and oral Chinese and Western patent medicine etc.When apoplexy state appears in patient, after sending to hospital, usually adopt intravenously administrable, about have the patient of 20% to cure, the patient of about 60% cannot cure, and causes sequela in various degree, also have an appointment 20% conditions of patients increase the weight of, even cause death, its effective percentage is low.When apoplexy appears in some patients, use acupuncture and moxibustion treatment, clinical discovery, indivedual Patients with Stroke can be taken a favorable turn by the state of an illness after acupuncture, but cure rate is low, and its effective percentage only has 10 ~ 20%; The patient also had is by Western medicine, and its medicine time is long, and sb.'s illness took a favorable turn slowly, and cure rate generally only has 10 ~ 15%, and its effective percentage is low equally.
We are badly in need of a kind of evident in efficacy, respond well medicine and help patient and solve the misery that apoplexy brings for this reason.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of apoplexy; Chinese medicine preparation of the present invention have restore menstrual flow and invigorate blood circulation, vessel softening, YIN nourishing and the production of body fluid promoting, wind dispelling refreshment effect, numb limbs and tense tendons, hypertension, hemiplegia that cerebral apoplexy sequela or transient ischemic attack are caused, have a dizzy spell, insomnia and dreamful sleep etc. has good therapeutic effect, and non-relapse after healing, the present invention makes simply, taking convenience, with low cost, without any side effects.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for apoplexy, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Cortex Eucommiae 62 ~ 92 parts of Flos Albiziaes 62 ~ 87 parts of Semen Persicaes 57 ~ 87 parts of Fructus Lycii 57 ~ 82 parts
Pheretima 52 ~ 82 parts of Flos Carthamis 47 ~ 77 parts of Caulis et Folium piperis 47 ~ 77 parts of Herba Cynomoriis 42 ~ 72 parts
Herba speranskiae tuberculatae 42 ~ 72 parts of Rhizoma Corydalis 37 ~ 67 portions of Lignum Sappans 32 ~ 62 parts of Xue Li 32 ~ 57 parts
12 ~ 42 parts, bar halberd 27 ~ 57 parts of Folium Craibiodendri Yunnanensiss 22 ~ 52 portions of Herba Menthaes 17 ~ 47 portions of Herba Cymbopogonis Citrari.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Cortex Eucommiae 67 ~ 87 parts of Flos Albiziaes 67 ~ 82 parts of Semen Persicaes 62 ~ 82 parts of Fructus Lycii 62 ~ 77 parts
Pheretima 57 ~ 77 parts of Flos Carthamis 52 ~ 72 parts of Caulis et Folium piperis 52 ~ 72 parts of Herba Cynomoriis 47 ~ 67 parts
Herba speranskiae tuberculatae 47 ~ 67 parts of Rhizoma Corydalis 42 ~ 62 portions of Lignum Sappans 37 ~ 57 parts of Xue Li 37 ~ 52 parts
17 ~ 37 parts, bar halberd 32 ~ 52 parts of Folium Craibiodendri Yunnanensiss 27 ~ 47 portions of Herba Menthaes 22 ~ 42 portions of Herba Cymbopogonis Citrari.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Cortex Eucommiae 72 ~ 82 parts of Flos Albiziaes 72 ~ 77 parts of Semen Persicaes 67 ~ 77 parts of Fructus Lycii 67 ~ 72 parts
Pheretima 62 ~ 72 parts of Flos Carthamis 57 ~ 67 parts of Caulis et Folium piperis 57 ~ 67 parts of Herba Cynomoriis 52 ~ 62 parts
Herba speranskiae tuberculatae 52 ~ 62 parts of Rhizoma Corydalis 47 ~ 57 portions of Lignum Sappans 42 ~ 52 parts of Xue Li 42 ~ 47 parts
22 ~ 32 parts, bar halberd 37 ~ 47 parts of Folium Craibiodendri Yunnanensiss 32 ~ 42 portions of Herba Menthaes 27 ~ 37 portions of Herba Cymbopogonis Citrari.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Cortex Eucommiae 77 parts of Flos Albiziaes 74 parts of Semen Persicaes 72 parts of Fructus Lycii 70 parts
Pheretima 67 parts of Flos Carthamis 62 parts of Caulis et Folium piperis 62 parts of Herba Cynomoriis 57 parts
Herba speranskiae tuberculatae 57 parts of Rhizoma Corydalis 52 portions of Lignum Sappans 47 parts of Xue Li 44 parts
27 parts, bar halberd 42 parts of Folium Craibiodendri Yunnanensiss 37 portions of Herba Menthaes 32 portions of Herba Cymbopogonis Citrari.
Treat a preparation method for the Chinese medicine preparation of apoplexy, comprise following processing step:
(1) Cortex Eucommiae, Flos Albiziae, bar halberd and Folium Craibiodendri Yunnanensis are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.11 ~ 1.18, for subsequent use;
(2) get Semen Persicae and Rhizoma Corydalis decontamination, dry, be placed in intense fire in pot and be fried to surface in yellow, taking-up is dried in the air cool, is placed in mortar and grinds into powder, crosses 200 order fine powders, for subsequent use;
(3) Fructus Lycii, Flos Carthami, Caulis et Folium piperis, Herba Cynomorii, Herba speranskiae tuberculatae, Lignum Sappan, Herba Menthae and Herba Cymbopogonis Citrari are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 60 DEG C, relative density is the thick paste of 1.15 ~ 1.22, for subsequent use;
(4) by Pheretima cutting, add yellow wine and soak 2-3 hour, dry after taking-up, cool to be placed in mortar and grind into powder, cross 160 order fine powders, for subsequent use;
(5) cleaned by Xue Li, chopping, strand juice, filter impurity, stays juice for subsequent use;
(6) by thick paste, juice and the fine powder mixing obtained by above-mentioned steps (1) ~ (5), utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of apoplexy of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
The Cortex Eucommiae: sweet in the mouth, micro-pungent, warm in nature; Enter liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening.Cure mainly spinal column ache, rheumatic arthralgia.Carry according to Prescriptions Worth Thousand Gold for Emergencies: " liver and kidney tonifying, fills blood for function wind-damp dispelling, stopping numbness pain, damp of having a cold, chills and pain of the waist and kness, podomere joint stuffiness, or benumbs meciless, fear of cold happiness temperature." modern medicine study confirms, the Cortex Eucommiae has sedation to nerve centre, can strengthen the immunologic function of cell, promotes cortisol secretion and cAMP in plasma and cGMP metabolism.
Flos Albiziae: sweet in the mouth, property is put down, nontoxic; GUIXIN, Liver Channel.Resolving depression, and blood, mind calming, subduing inflammation.Cure mainly irritability, melancholy, insomnia, lung abscess, carbuncle, scrofula, injured bone.Nanchuan " conventional Chinese herbal medicine handbook " is carried: " control that the motive is restless, insomnia and clonic spasm of the muscle.”
Semen Persicae: bitter in the mouth, sweet, property is put down; GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Cure mainly amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation." herbal classic is met former " carries: " Semen Persicae is the special medicine that blood stasis blood closes.Bitter to let out stagnant blood, sweetly control invasion of the blood-chamber by heat with tissue regeneration promoting blood, the stasis of blood amasss lump in the abdomen, malaria with splenomegaly, cardiac and abdominal pain, also the blood agglomeration of loose Liver Channel." modern medicine study confirmation, Semen Persicae alcohol extract can increase vein blood vessel flow, vasodilator, increases femoral artery blood flow, reduces vascular resistance, has direct dilating effect to blood vessel wall, also has in addition and suppresses blood coagulation and haemolysis.
Fructus Lycii: sweet in the mouth, property is put down; Return liver, kidney, lung meridian.Nourishing the liver, nourishing kidney, lung moistening.Cure mainly caused by liver and kidney deficiency, have a dizzy spell, visual unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, taking fluids profusely of quenching one's thirst.Compendium of Material Medica is carried: " take hard muscles and bones for a long time, make light of one's life by commiting suicide not old, resistance to cold and summer-heat." modern pharmacology research confirm, Fructus Lycii scalable body's immunity, can effectively Tumor suppression grow and cell mutation, there is the effect of the aspect such as slow down aging, anti-fatty liver, adjusting blood lipid and blood glucose, promotion hemopoietic function, and be applied to clinical.
Pheretima: salty in the mouth, cold in nature.Clearing away heat and relieving spasm, diuresis is detoxified.Cure mainly calentura mania and irritation, infantile convulsion, cough with asthma, headache conjunctival congestion, laryngopharynx swelling and pain, urinary obstruction, Fengshi Guanjie pain, the diseases such as hemiplegia; External is coated with erysipelas, the diseases such as dermatitis rhus.Compendium of Material Medica is carried: " Pheretima is referred to as to have dredge the meridian passage, blood circulation promoting and blood stasis dispelling, the effect of prophylactic treatment cardiovascular and cerebrovascular disease.”
Flos Carthami: acrid in the mouth, warm in nature; GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Cure mainly dysmenorrhea, amenorrhea, puerperal blood faints, the stagnant stomachache of the stasis of blood, obstruction of qi in the chest and cardialgia, accumulation of blood, traumatic injury congestive edema, arthralgia, paralysis due to windstroke, macular eruption being dark-purple etc. have good curative effect.To invigorate blood circulation latus rectum, eliminating stasis to stop pain." book on Chinese herbal medicine just " carries: " reach variola heat in blood difficulty to go out, the stasis of speckle rash does not disappear.”
Caulis et Folium piperis: acrid in the mouth, warm in nature; Return liver, spleen channel.Wind-damp dispelling, relaxing muscles and tendons network, strong waist knee joint, except arthralgia pain.For anemofrigid-damp arthralgia, bones and muscles pain.Weakness of the waist and knees, cough and asthma, cough of suffering from a deficiency of the kidney, sexual impotence.
Herba Cynomorii: sweet in the mouth, warm in nature; Enter liver, kidney channel.The kidney invigorating intestine moistening.Cure mainly sexual impotence, hematuria, blood depletion constipation, waist knee flaccidity." Inner Mongol Chinese herbal medicine " carries: " control impotence and seminal emission, lassitude loin and legs, neurasthenia, senile constipation." scientific experiments proves, Herba Cynomorii has the effect of anti-cancer, antiviral, slow down aging, is applicable to hypoimmunity, easy infection disease patient.
Herba speranskiae tuberculatae: acrid in the mouth, hardship, warm in nature, slightly poisonous; Return liver, kidney channel.Expelling wind and removing dampness, removing toxic substances pain relieving, for rheumatic arthritis, controls sore swollen toxin.Carry according to " Chinese herbal medicine handbook is commonly used in northeast ": " relaxing muscles and tendons to promote blood circulation, wind-expelling pain-stopping.Control lumbago and skelalgia, Kaschin-Beck disease arthralgia, muscles and bones is numb, bruise, lumbar sprain and QI divergeny.”
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature.Promoting blood circulation to remove blood stasis, regulating QI to relieve pain.For whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain." Kaibao Bencao " carries: " warm in nature, acrid in the mouth is bitter; Enter the heart, spleen, liver, lung, be the quality goods of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, be especially world-famous for effect of pain relieving.”
Lignum Sappan: sweet in the mouth, salty, property is put down; GUIXIN, liver, spleen channel.Promoting the circulation of blood blood stasis dispelling, reducing swelling and alleviating pain.For amenorrhea dysmenorrhea, postpartum stagnation, breast ventral spine pain, wound swells and ache." Haiyao Bencao, Oversea Materia Medica " carries: " main asthenia blood addiction gas is stopped up stagnant; Lochia is uneasy, stirs pain in abdomen; And blockage of main and collateral channels, men and women's apoplexy, trismus and inability to speak.Carefully should grind the fragrant smalls tool for weighing medicine in ancient China of nipple, the Jiu Jian Soviet side goes dregs to be taken after mixing with liquid, and vertical evil thing of telling is recovered.”
Xue Li: sour in the mouth, cool in nature.Expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome, sciatica, dysentery, urine drenches, edema, malaria, amenorrhea, and postnatal blood stasis is suffered from abdominal pain, laryngopharynx swelling and pain, orchitis, dermatitis rhus, pain pyogenic infections from tumour or sore, traumatic injury." Chinese herbal medicine is commonly used in Shanghai " carries: " wind-damp dispelling, dredge the meridian passage, clearing heat for detumescence, diuresis, hemostasis.Dispelling the wind and dampness pathogens pain, brothers' articular instability.”
Ba Ji: sweet in the mouth, pungent, slightly warm in nature.Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.Radix Morindae Officinalis can kidney-replenishing, benefiting essence-blood, bone and muscle strengthening, wind-damp dispelling.The sexual impotence for the treatment of deficiency of kidney yang, infertile, menoxenia, few abdomen cold type of pain.Also the muscles and bones flaccidity can treating deficiency of the liver and kindey is soft, lumbocrural pain, or rheumatism lingering arthralgia, walks with difficulty.
Folium Craibiodendri Yunnanensis: acrid in the mouth, puckery, warm in nature.Eliminating stasis to stop pain, expelling wind and removing dampness, stops blooding sensible.For traumatic injury, traumatic stupor, bruise, lumbago and skelalgia, hemiplegia, paralysis, rheumatic arthritis, traumatic hemorrhage, fracture." choosing of Yunnan Chinese herbal medicine " carries: " relaxing muscles and tendons and activating QI and blood in the collateral.Control fracture, rheumatism, traumatic injury, paralysis.”
Herba Menthae: acrid in the mouth, cool in nature; Enter lung, Liver Channel.Dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving rash, soothing the liver circulation of qi promoting.Cure mainly affection due to external wind and heat, headache, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria, epidemic febrile disease from the beginning of, rubella pruritus, stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest." a thousand pieces of gold dietetic therapy " carries: " dynamic diabetes." modern medicine confirms, Herba Menthae can the emotion of nervous indignation gently, spirit can be improved, make body and mind vigorously pleased, help fall asleep, have certain assosting effect to central nervous system.
Herba Cymbopogonis Citrari: acrid in the mouth, sweet, warm in nature.Dispelling wind and removing obstruction in the collateral, warming middle-JIAO to relieve pain, antidiarrheal.Cure mainly flu head-body-pain, anemofrigid-damp arthralgia, coldness and pain in the epigastrium, have loose bowels, traumatic injury." south of the Five Ridges gather medicinal herbs record " carries: " loose traumatic injury hinders blood stasis, the meridian dredging.Wind syndrome of head pain, decocts washing with it.Herba Cymbopogonis Citrari and rice are fried together, add decocting drink, sealing rushes down.Decoct washing body, detumescence of can dispeling the wind, separate stench.Extract its oil, can only suffer from abdominal pain.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention have restore menstrual flow and invigorate blood circulation, vessel softening, YIN nourishing and the production of body fluid promoting, wind dispelling refreshment effect, numb limbs and tense tendons, hypertension, hemiplegia that cerebral apoplexy sequela or transient ischemic attack are caused, have a dizzy spell, insomnia and dreamful sleep etc. has good therapeutic effect, and non-relapse after healing, the present invention makes simply, taking convenience, with low cost, without any side effects.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Cortex Eucommiae 87g Flos Albiziae 82g Semen Persicae 82g Fructus Lycii 77g
Pheretima 77g Flos Carthami 72g Caulis et Folium piperis 72g Herba Cynomorii 67g
Herba speranskiae tuberculatae 67g Rhizoma Corydalis 62g Lignum Sappan 57g Xue Li 52g
Bar halberd 52g Folium Craibiodendri Yunnanensis 47g Herba Menthae 42g Herba Cymbopogonis Citrari 37g.
Treat a preparation method for the Chinese medicine preparation of apoplexy, comprise following processing step:
(1) Cortex Eucommiae, Flos Albiziae, bar halberd and Folium Craibiodendri Yunnanensis are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.11 ~ 1.18, for subsequent use;
(2) get Semen Persicae and Rhizoma Corydalis decontamination, dry, be placed in intense fire in pot and be fried to surface in yellow, taking-up is dried in the air cool, is placed in mortar and grinds into powder, crosses 200 order fine powders, for subsequent use;
(3) Fructus Lycii, Flos Carthami, Caulis et Folium piperis, Herba Cynomorii, Herba speranskiae tuberculatae, Lignum Sappan, Herba Menthae and Herba Cymbopogonis Citrari are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 60 DEG C, relative density is the thick paste of 1.15 ~ 1.22, for subsequent use;
(4) by Pheretima cutting, add yellow wine and soak 2-3 hour, dry after taking-up, cool to be placed in mortar and grind into powder, cross 160 order fine powders, for subsequent use;
(5) cleaned by Xue Li, chopping, strand juice, filter impurity, stays juice for subsequent use;
(6) by thick paste, juice and the fine powder mixing obtained by above-mentioned steps (1) ~ (5), utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of apoplexy of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 8 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Cortex Eucommiae 82g Flos Albiziae 77g Semen Persicae 77g Fructus Lycii 72g
Pheretima 72g Flos Carthami 67g Caulis et Folium piperis 67g Herba Cynomorii 62g
Herba speranskiae tuberculatae 62g Rhizoma Corydalis 57g Lignum Sappan 52g Xue Li 47g
Bar halberd 47g Folium Craibiodendri Yunnanensis 42g Herba Menthae 37g Herba Cymbopogonis Citrari 32g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Cortex Eucommiae 77g Flos Albiziae 74g Semen Persicae 72g Fructus Lycii 70g
Pheretima 67g Flos Carthami 62g Caulis et Folium piperis 62g Herba Cynomorii 57g
Herba speranskiae tuberculatae 57g Rhizoma Corydalis 52g Lignum Sappan 47g Xue Li 44g
Bar halberd 42g Folium Craibiodendri Yunnanensis 37g Herba Menthae 32g Herba Cymbopogonis Citrari 27g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Cortex Eucommiae 72g Flos Albiziae 72g Semen Persicae 67g Fructus Lycii 67g
Pheretima 62g Flos Carthami 57g Caulis et Folium piperis 57g Herba Cynomorii 52g
Herba speranskiae tuberculatae 52g Rhizoma Corydalis 47g Lignum Sappan 42g Xue Li 42g
Bar halberd 37g Folium Craibiodendri Yunnanensis 32g Herba Menthae 27g Herba Cymbopogonis Citrari 22g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Cortex Eucommiae 67g Flos Albiziae 67g Semen Persicae 62g Fructus Lycii 62g
Pheretima 57g Flos Carthami 52g Caulis et Folium piperis 52g Herba Cynomorii 47g
Herba speranskiae tuberculatae 47g Rhizoma Corydalis 42g Lignum Sappan 37g Xue Li 37g
Bar halberd 32g Folium Craibiodendri Yunnanensis 27g Herba Menthae 22g Herba Cymbopogonis Citrari 17g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of apoplexy, select the routine clinical observation of Patients with Stroke 200 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 100 example, wherein male 49 example, women 51 example, 45 ~ 75 years old age, 60 years old mean age, the shortest person of the course of disease 3 months, most elder 8 years, average 4.5 years.Matched group 100 example, wherein male 50 example, women 50 example, 46 ~ 76 years old age, 61 years old mean age, the shortest person of the course of disease 4 months, most elder 7 years, average 4.1 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 8 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2 ~ 3 courses for the treatment of.
Matched group dosed herself with aspirin, oral, every day 4 times, each 3 ~ 5g 9 days is 1 course for the treatment of, 1 course for the treatment of of the lighter, and severe one can be fully recovered 2 ~ 3 courses for the treatment of.
3, efficacy determination:
(1) cure: stroke symptom all disappears, physical recovery is normal, and body index recovers normal on inspection.
(2) take a turn for the better: stroke symptom disappears substantially, body index part takes a turn for the better on inspection.
(3) invalid: by treating rear stroke symptom without improvement.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 68 examples, take a turn for the better 29 examples, invalid 3 examples, cure rate 68%, total effective rate 97%.
Cure 35 examples in matched group, take a turn for the better 23 examples, invalid 42 examples, cure rate 10%, total effective rate 58%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Wu, man, 48 years old, businessman, people from Dezhou, Shandong.Patient suffers from apoplexy, does operation of opening cranium, but has caused serious cerebral apoplexy sequela, left limb muscular strength obviously increases, and more so, left upper extremity flexing is serious for left lower extremity, the facial muscular paralysis in left side is unable simultaneously, loses the ability of taking care of oneself, has a strong impact on the daily life of patient.Once use multiple Drug therapy, lose improvement always.To our hospital afterwards, take Chinese medicine preparation of the present invention, after taking 1 course for the treatment of, left upper extremity joint motion is stretched and is lifted normally, and left side face muscular paralysis symptom disappears, after continuing to take 1 course for the treatment of substantially, left side facial muscle are without paralysis sensation, and life is taken care of oneself completely, is back on the job.
2, poplar, female, 53 years old, college professor, people from Baoding.Patient's WA in morning, sensation left hand is unable, and left foot is weak, removes hospital admission, and CT points out bilateral basal joint, bilateral thalamus, right temporo radioactivity multiple cerebral infarction.With crossing multiple Drug therapy, poor effect.To our hospital afterwards, after taking 1 course for the treatment of of Chinese medicine preparation of the present invention, patient can squat down, bend over, left foot muscular strength, to put forth effort, stride steadily, upper limb joint activity stretch lift normal, stretch act Myodynamia recovery, but have paralysis sensation when stretching act, blood pressure recovers to drop to 75 ~ 130mmHg.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, patient's left foot muscular strength is bent dynamic normal, squat down, bend over, stride, put forth effort steadily effectively, left arm joint motion nature, without soft pain, without paralysis sensation, five fingers are clenched fist in the wrong dynamic strong, and blood pressure stabilization is at 75 ~ 125mmHg, mind consciousness is normal, and life is taken care of oneself completely.
3, Song, man, 65 years old, retired worker, people from Xuzhou.Patient falls on the ground suddenly, namely gives certain county people's hospital to give treatment to, and CT prompting left side top cerebral hemorrhage 29cc, use intravenous drip administration, though the state of an illness take a favorable turn, the right hand loses muscular strength, and right crus of diaphragm loses to be puted forth effort.To our hospital afterwards, patient loses sick after belonging to hemorrhagic apoplexy on inspection, and right crus of diaphragm can not be raised, slightly kinetic energy translation, but lose muscular strength, put forth effort, right hand shoulder joint can bitterly, and muscular strength is poor, and the right hand the five fingers can not bend and stretch, inwardly partly clench fist, mind is not good enough, and hemiplegia, at bed, be can't take care of oneself.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, patient's right crus of diaphragm muscular strength takes a turn for the better, hand steered wall can slowly be walked; After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, right crus of diaphragm is puted forth effort to recover, and patient can stride alone and go slowly, and the right hand the five fingers are flexible, but without grip; Continuous take 1 course for the treatment of of Chinese medicine preparation of the present invention after, find that patient's right crus of diaphragm muscular strength is puted forth effort normally, squatting down, it is steadily strong to bend over, the five fingers stretch in the wrong, stretch act, clench fist strong, energy firewood of being in, to cook, rehabilitation is to normal healthy level.
4, high certain, female, 71 years old, peasant, people from Shenyang, Liaoning.Patient suffers from apoplexy, and walking falls down to remain unconscious one hour in way, is sent to hospital in time, on inspection, suffer from lose after hemorrhagic apoplexy sick, after take Chinese medicine preparation of the present invention and within 2 days, namely wake up and turn, after adhere to taking 1 course for the treatment of of Chinese medicine preparation of the present invention, conscious mind, afterwards without recurrence.
Claims (5)
1. treat a Chinese medicine preparation for apoplexy, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Cortex Eucommiae 62 ~ 92 parts of Flos Albiziaes 62 ~ 87 parts of Semen Persicaes 57 ~ 87 parts of Fructus Lycii 57 ~ 82 parts
Pheretima 52 ~ 82 parts of Flos Carthamis 47 ~ 77 parts of Caulis et Folium piperis 47 ~ 77 parts of Herba Cynomoriis 42 ~ 72 parts
Herba speranskiae tuberculatae 42 ~ 72 parts of Rhizoma Corydalis 37 ~ 67 portions of Lignum Sappans 32 ~ 62 parts of Xue Li 32 ~ 57 parts
12 ~ 42 parts, bar halberd 27 ~ 57 parts of Folium Craibiodendri Yunnanensiss 22 ~ 52 portions of Herba Menthaes 17 ~ 47 portions of Herba Cymbopogonis Citrari.
2. a kind of Chinese medicine preparation for the treatment of apoplexy according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Cortex Eucommiae 67 ~ 87 parts of Flos Albiziaes 67 ~ 82 parts of Semen Persicaes 62 ~ 82 parts of Fructus Lycii 62 ~ 77 parts
Pheretima 57 ~ 77 parts of Flos Carthamis 52 ~ 72 parts of Caulis et Folium piperis 52 ~ 72 parts of Herba Cynomoriis 47 ~ 67 parts
Herba speranskiae tuberculatae 47 ~ 67 parts of Rhizoma Corydalis 42 ~ 62 portions of Lignum Sappans 37 ~ 57 parts of Xue Li 37 ~ 52 parts
17 ~ 37 parts, bar halberd 32 ~ 52 parts of Folium Craibiodendri Yunnanensiss 27 ~ 47 portions of Herba Menthaes 22 ~ 42 portions of Herba Cymbopogonis Citrari.
3. a kind of Chinese medicine preparation for the treatment of apoplexy according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Cortex Eucommiae 72 ~ 82 parts of Flos Albiziaes 72 ~ 77 parts of Semen Persicaes 67 ~ 77 parts of Fructus Lycii 67 ~ 72 parts
Pheretima 62 ~ 72 parts of Flos Carthamis 57 ~ 67 parts of Caulis et Folium piperis 57 ~ 67 parts of Herba Cynomoriis 52 ~ 62 parts
Herba speranskiae tuberculatae 52 ~ 62 parts of Rhizoma Corydalis 47 ~ 57 portions of Lignum Sappans 42 ~ 52 parts of Xue Li 42 ~ 47 parts
22 ~ 32 parts, bar halberd 37 ~ 47 parts of Folium Craibiodendri Yunnanensiss 32 ~ 42 portions of Herba Menthaes 27 ~ 37 portions of Herba Cymbopogonis Citrari.
4. a kind of Chinese medicine preparation for the treatment of apoplexy according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Cortex Eucommiae 77 parts of Flos Albiziaes 74 parts of Semen Persicaes 72 parts of Fructus Lycii 70 parts
Pheretima 67 parts of Flos Carthamis 62 parts of Caulis et Folium piperis 62 parts of Herba Cynomoriis 57 parts
Herba speranskiae tuberculatae 57 parts of Rhizoma Corydalis 52 portions of Lignum Sappans 47 parts of Xue Li 44 parts
27 parts, bar halberd 42 parts of Folium Craibiodendri Yunnanensiss 37 portions of Herba Menthaes 32 portions of Herba Cymbopogonis Citrari.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine preparation of apoplexy, it is characterized in that: comprise following processing step:
(1) Cortex Eucommiae, Flos Albiziae, bar halberd and Folium Craibiodendri Yunnanensis are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, filter, at simmer down to 65 DEG C, relative density is the thick paste of 1.11 ~ 1.18, for subsequent use;
(2) get Semen Persicae and Rhizoma Corydalis decontamination, dry, be placed in intense fire in pot and be fried to surface in yellow, taking-up is dried in the air cool, is placed in mortar and grinds into powder, crosses 200 order fine powders, for subsequent use;
(3) Fructus Lycii, Flos Carthami, Caulis et Folium piperis, Herba Cynomorii, Herba speranskiae tuberculatae, Lignum Sappan, Herba Menthae and Herba Cymbopogonis Citrari are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 60 DEG C, relative density is the thick paste of 1.15 ~ 1.22, for subsequent use;
(4) by Pheretima cutting, add yellow wine and soak 2-3 hour, dry after taking-up, cool to be placed in mortar and grind into powder, cross 160 order fine powders, for subsequent use;
(5) cleaned by Xue Li, chopping, strand juice, filter impurity, stays juice for subsequent use;
(6) by thick paste, juice and the fine powder mixing obtained by above-mentioned steps (1) ~ (5), utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation of described treatment apoplexy.
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| CN103285278A (en) * | 2013-06-18 | 2013-09-11 | 冯宇伟 | Medicament for preventing and treating ischemic cerebral apoplexy and preparation method thereof |
| CN103386016A (en) * | 2013-07-19 | 2013-11-13 | 纪振起 | Blood circulation-promoting and collateral-activating pill |
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| CN101683471A (en) * | 2008-09-23 | 2010-03-31 | 天津市中宝制药有限公司 | Traditional Chinese medicine composition with function of brain tonic and vein relaxing |
| CN103285278A (en) * | 2013-06-18 | 2013-09-11 | 冯宇伟 | Medicament for preventing and treating ischemic cerebral apoplexy and preparation method thereof |
| CN103386016A (en) * | 2013-07-19 | 2013-11-13 | 纪振起 | Blood circulation-promoting and collateral-activating pill |
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