CN104435230A - Medicine for treating osteoporosis and preparation method of medicine - Google Patents
Medicine for treating osteoporosis and preparation method of medicine Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention discloses a medicine for treating osteoporosis and a preparation method of the medicine, and belongs to the field of traditional Chinese medicines. The effective components of the medicine disclosed by the invention are prepared from the following raw materials: psychotria serpens, quail, membranaceous beautyleaf root, ventilago leiocarpa benth, thesium chinensis, mussel, sambucus adnata, philippine flemingia root, lichen of parmelia saxitilis, hoya lancilimba, angelica sinensis, false nettleleaf pepper herb, cabbage, cinnamomum burmanni peel, liquorice and herba pyrolae. The medicine is appropriate of compatibility, has the efficacies of building bodies, invigorating bones, invigorating the spleen, replenishing qi, relaxing spasm, relieving pain, tonifying kidneys and deficiency, eliminating dampness, dredging channels, coordinating the drug actions of a prescription by combination of a plurality of medicinal materials, has the advantages of being fast in acting, high in recovery rate, free of toxic or side effect, safe and convenient on the treatment of osteoporosis, and has relatively significant effects of lubricating joints, and strengthening tendons and bones; meanwhile, the immunity of a human body is obviously improved; and the medicine can be widely applied to clinical treatment of the osteoporosis.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and the preparation method that are used for the treatment of osteoporosis.
Background technology
Osteoporosis is a kind of systemic osteopathia, it is characterized in that bone amount declines and the fine structure of bone destroys, the fragility showing as bone increases, and thus the danger of osteoporosis greatly increases, even also easily there is osteoporosis in slight wound or atraumatic situation.Osteoporosis is a kind of multifactor caused chronic disease.Before osteoporosis occurs, usually without Special Clinical Manifestation.This sick women, more than male, is common in postmenopausal women and old people.Along with the increase of China's aging population, developing osteoporosis rate is in ascendant trend, is all a health problem merited attention in China and even the whole world.
The modal symptom of primary osteoporosis, common with lumbago and backache, account for the 70%-80% in pain patients.Osteodynia can be there is when general bone loss more than 12%.Height shortens, hunchback is many occurs after pain.Osteoporosis is the most common and the most serious complication of degeneration osteoporosis.Thoracolumbar vertebrae compression osteoporosis disease, vertebra palintrope, chest deformity, can make vital capacity and maximal breathing capacity significantly reduce, patient often can occur uncomfortable in chest, breathe hard, the symptom such as dyspnea.
The modal complication of osteoporosis is fracture, and slight external force can cause fracture, as cough fracture of rib can occur.Within more than 60 years old, the concurrent fracture person of senile osteoporosis is up to 12%.The lighter can make limitation of activity, and severe one palpus long-term bed, causes very large burden to society and household.Senile fracture can cause or increase the weight of cardiovascular and cerebrovascular complication, causes the generation of the multiple complications such as pulmonary infection and decubital ulcer, and serious harm old people's is healthy, even threat to life, and mortality rate can reach 10% ~ 20%.Osteoporotic hazardness is also that it is usually noiseless, generation silently quietly.Majority do not have manifest symptom, and along with age increase, bone calcium is in continuous loss, once there is symptom, bone calcium is usually lost and reached more than 50%, and short term therapy is difficult to prove effective.
The method of current treatment osteoporosis is mainly based on Drug therapy, but Drug therapy has side effect, and treatment slowly, fully effectively can not reach the effect for the treatment of osteoporosis.For this reason, we are badly in need of developing a kind of medicine and help patient and break away from the misery that osteoporosis brings.
Summary of the invention
The invention provides a kind of medicine and the preparation method that are used for the treatment of osteoporosis; Compatibility of drugs of the present invention is suitable, all medicines are harmonious with having and keep fit effect of strong bone, invigorating the spleen and replenishing QI, relieving spasm to stop pain, kidney tonifying tonify deficiency, eliminating dampness and dredging channels, coordinating the actions of various ingredients in a prescription, for treatment osteoporosis have instant effect, cure rate high, have no side effect, the advantage of safe ready, there is the effect of comparatively significant lubricating joint, strengthening the tendons and bones, significantly improve the immunity of human body simultaneously, the clinical treatment of osteoporosis can be widely used in.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine for osteoporosis, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Be used for the treatment of a preparation method for the medicine of osteoporosis, comprise following processing step:
(1) Ramulus et Folium Psychotriae Serpentis, Carnis Coturnicis japonicae, Radix calophylli membranacei, Mytilus, Herba Sambuci Adnatae, Radix Flemingiae Philippinensis, Herba Hoyae lancilimbae and Radix Glycyrrhizae are put into container, first add 10-15 times amount distilled water immersion after 4-5 hour, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge extractive liquid, filters, obtains filtrate for subsequent use;
(2) Radix seu Caulis Verntilaginis Leiocarpae, Parmelia saxatilis Ach. and Caulis Piperis Boehmeriaefolii are immersed 10 times amount volumetric concentration 70% alcohol solution dipping 4 hours, heating extraction, filter, after leaving standstill, reclaiming ethanol and being concentrated into 60 DEG C of relative densities is that the thick paste of 1.12-1.15 is for subsequent use;
(3) by Herba Thesii, Cortex Cinnamomi Burmannii and Herba Pyrolae microwave drying, grind into powder, cross 100 order fine powders, for subsequent use;
(4) Radix Angelicae Sinensis is used yellow wine uniform spraying, slightly vexed, put in pot and fry with low baking temperature, take out, cool, grind into powder, cross 160 order fine powders, for subsequent use;
(5) Caulis et Folium Brassicae capitatae is twisted juice, filter impurity, stays juice, for subsequent use;
(6) by filtrate obtained for step (1)-(5), thick paste, fine powder and juice mixing, make medicine, be the medicine being used for the treatment of osteoporosis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Ramulus et Folium Psychotriae Serpentis: bitter in the mouth, pungent, property is put down; Return liver, heart channel.Wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain.Main rheumatic arthritis, numb hand and foot, psoas muscle labor fingerprint, sciatica, multiple carbuncle, bone tuberculosis, traumatic injury, osteoporosis, venom." Guangdong Chinese medicine " carries: " analeptic, controls lumbago; Be again the analgesic that stimulates the menstrual flow, can dissipate skin ulcer, goes larynx to swell and ache; Waist pain all over the joints and arthralgia can be controlled again.”
Carnis Coturnicis japonicae: sweet in the mouth, property is put down; Return large intestine, the heart, liver, spleen, lung, kidney channel.Gas in benefit, stopping leak dysentery, strengthening bone and muscle.Main insufficiency of the spleen dysentery, infantile malnutrition, rheumatism arthromyodynia, cough.The Meng, stream was said: " tonifying five ZANG-organs, continuous gas in benefit, real muscles and bones, resistance to cold and summer-heat, disappear stagnation of pathogenic heat.It is cooked by trouble dysentery people and Rhizoma Zingiberis Recens.”
Radix calophylli membranacei: mildly bitter flavor, property is put down; Return liver, kidney channel.Wind-damp dispelling, bone and muscle strengthening, promoting blood circulation and stopping pain.Main air arthralgia chiefly caused by damp pathogen is demonstrate,proved, lumbago due to renal deficiency, menoxenia, dysmenorrhea, traumatic injury.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " stasis-dispelling and pain-killing, replenishing kidney, strengthening waist.Control traumatic injury, rheumatic ostalgia, lumbago due to renal deficiency.”
Radix seu Caulis Verntilaginis Leiocarpae: sweet in the mouth, warm in nature; Return lung, spleen channel.Fill blood, bone and muscle strengthening, relax meridians.Main deficient qi and blood, has through uncomfortable, blood deficiency amenorrhea, rheumatalgia, traumatic injury, lumbar muscle strain.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " rich in nutrition, relaxing muscles and tendons and activating QI and blood in the collateral.Control deficiency of both QI and blood, menoxenia, bones and muscles pain due to rheumatism, numb limbs and tense tendons, traumatic injury.”
Herba Thesii: acrid in the mouth, micro-hardship, cold in nature; Return spleen, kidney channel.Heat clearing away, dampness removing, removing toxic substances.Main anemopyretic cold, heatstroke, lung abscess, tonsillitis, tuberculous lymphadenitis, mastalgia, furuncle and phyma, stranguria, yellow cellulitis, lumbago, seminal emission." Guizhou side among the people medicine collection " carries: " control dizzy weak, lumbago, seminal emission, spermatorrhea." modern medicine study confirmation, thesine II pair of staphylococcus aureus, micrococcus catarrhalis, Bacillus typhi, Bacillus proteus, dysentery bacterium all have inhibitory action; Thesine I only has inhibitory action to staphylococcus aureus, micrococcus catarrhalis, dysentery bacterium.
Mytilus: sweet in the mouth, salty, warm in nature; Return liver, kidney channel.Invigorating the liver and kidney, benefiting essence-blood, disappear goiter.Main asthenia weakness and emaciation, dizzy, night sweat, sexual impotence, lumbago, spits blood, metrorrhagia, leukorrhagia, goiter.Supplement to the Herbal carries: " strain of main weakness with emaciation, thin and weak because producing, vim and vigour knot is long-pending, abdomen is cold, borborygmus, dysentery, pain in the lumbar region, leukorrhagia, hernia abdominal mass.”
Herba Sambuci Adnatae: acrid in the mouth, sweet, warm in nature; Return spleen, kidney channel.Dispel the wind, diuretic, invigorates blood circulation, dredging collateral.Main acute and chronic nephritis, rheumatalgia, rubella pruritus, children's's single board computer numbness sequela, chronic lambago and skelalgia, sprains stasis of blood pain, osteoporosis." Chinese herbal medicine is commonly used in Tibet " carries: " promoting blood circulation to remove blood stasis, bone and muscle strengthening, wind-damp dispelling, inducing diuresis to remove edema.Treating rheumatic arthritis, chronic lambago and skelalgia, sprains, hematoma, edema." modern medicine study confirmation, Herba Sambuci Adnatae decoct has antifungic action to trichophyton, trichophyton gypseum, acrothesium floccosum, microsporum canis and microsporon gypseum etc. in vitro.
Radix Flemingiae Philippinensis: sweet in the mouth, puckery, property is put down; Return lung, kidney, urinary bladder channel.Expelling wind and removing dampness, bone and muscle strengthening, promoting blood circulation and detoxication.Main air pain of dampness syndrome, lumbar muscle strain, extremity flaccidity is soft, traumatic injury, laryngopharynx swelling and pain." south of the Five Ridges gather medicinal herbs record " carries: " dispel wind and remove dampness.Control brothers' arthralgia pain, lumbar rheumatism is had a pain, and reason traumatic injury wound, can relaxing muscles and tendons and activating QI and blood in the collateral.”
Parmelia saxatilis Ach.: sweet in the mouth, property is put down; Return liver, kidney channel.Invigrating kidney, improving eyesight, hemostasis, eliminating damp, detoxifying.Main blurred vision, lumbocrural pain, spits blood, metrorrhagia jaundice, skin ulcer tinea." the conventional Chinese herbal medicine handbook in the north " carries: " strengthening bone and muscle, eliminate indigestion gathers for nourishing blood for improving eyesight, benefit essence.Control blurred vision, lumbago and skelalgia, enclosed mass in abdomen, hepatitis.”
Herba Hoyae lancilimbae: bitter in the mouth, pungent, cool in nature; Return Liver Channel.Promoting blood circulation to remove blood stasis, expelling wind and removing dampness.Main air damp-heat arthralgia, treating swelling and pain by traumatic injury, osteoporosis." Xinhua book on Chinese herbal medicine outline " carries: " stem and leaf: bitter in the mouth, pungent, cool in nature.There is blood circulation promoting and blood stasis dispelling, the function of expelling wind and removing dampness.For rheumatic arthralgia, traumatic injury and refute bone etc.”
Radix Angelicae Sinensis: sweet in the mouth, pungent, bitter, warm in nature; Return liver, the heart, spleen channel.Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.The all cards of main blood deficiency, menoxenia, amenorrhea, dysmenorrhea, lump in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, heavy after bloody dysentery, ulcer sores, injury from falling down." not Lu " carries: " warming middle-JIAO to relieve pain, fills in except in objective blood, middle puerperal tetanus, no sweating, arthralgia chiefly caused by damp pathogen, and attacked by pestiferous factors is courteous, cold caused by deficiency, tonifying five ZANG-organs, granulation promoting meat.”
Caulis Piperis Boehmeriaefolii: acrid in the mouth, warm in nature; Return lung, the heart, liver, spleen, stomach warp.Expelling wind and removing dampness, eliminating dampness and dredging channels.Main cold, rheumatic arthralgia, stomachache, menoxenia, traumatic injury, osteoporosis." Yunnan Chinese herbal medicine " carries: " relaxing muscles and tendons and activating QI and blood in the collateral, warming the meridian dampness removing, promoting the circulation of QI to relieve pain.Dispelling the wind and dampness pathogens, menoxenia, stomachache, traumatic injury.”
Caulis et Folium Brassicae capitatae: sweet in the mouth, property is put down; Return stomach, kidney channel.Eliminating damp-heat, removing obstruction for relieving pain, kidney tonifying tonify deficiency.Main jaundice due to damp-heat, digestive tract ulcer pain, articular instability, deficient.Supplement to the Herbal carries: " Psoralen marrow, profit five hides six internal organs, sharp joint, stagnation of QI in the meridian dredging, improve visual and auditory acuity, and strong people, sleeps less, beneficial mental and physical efforts, strengthening bone and muscle.Harness the Yellow River poison, Zhu Zuo Potamogeton is through place stain yellow skin, and it is eaten by salt.Latent pathogen is tied under removing the heart.”
Cortex Cinnamomi Burmannii: acrid in the mouth, micro-sweet, warm in nature; Return spleen channel.Warming middle-JIAO to relieve pain, expelling wind and cold, removing toxic substances and promoting subsidence of swelling, hemostasis.Cure mainly cold stomachache, stomachache is had loose bowels, inappetence, anemofrigid-damp arthralgia, lumbago and skelalgia, traumatic injury, wound hemorrhage, furuncle toxic swelling." conventional Chinese herbal medicine color atlas " carries: " detumescence of dispeling the wind, astringing to arrest diarrhea.Treating rheumatic arthritis, lumbago and skelalgia, osteopatia sprain, furuncle and phyma sore, wound hemorrhage, watery diarrhea, cold stomach stomachache, inappetence, amenorrhea.”
Radix Glycyrrhizae: sweet in the mouth, property is put down; GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong." Japan hanako materia medica " carries: " peace soul determines soul.Mend five kinds of strain and seven kinds of impairment, all be deficient, palpitation with fear, unhappy, forgetful.Logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle, separates cold and hot.”
Herba Pyrolae: sweet in the mouth, hardship, warm in nature; Return liver, kidney channel.The kidney invigorating bone strengthening, expelling wind and removing dampness, cough-relieving, hemostasis.Main lumbago due to renal deficiency, pain of dampness syndrome, muscles and bones flaccidity is soft, and new chronic cough is coughed, and spits blood, epistaxis, metrorrhagia, traumatic hemorrhage." Shaanxi Chinese herbal medicine " carries: " kidney invigorating and YANG supporting, regulating menstruation and activating blood, astringing to arrest bleeding.Control cough due to consumptive disease, night sweat of suffering from a deficiency of the kidney, weakness of the waist and knees, rheumatism and rheumatoid arthritis, hemiplegia, metrorrhagia, leucorrhea, conjunctivitis, various hemorrhage.”
The present invention compared with prior art, has following beneficial effect:
Compatibility of drugs of the present invention is suitable, all medicines are harmonious with having and keep fit effect of strong bone, invigorating the spleen and replenishing QI, relieving spasm to stop pain, kidney tonifying tonify deficiency, eliminating dampness and dredging channels, coordinating the actions of various ingredients in a prescription, for treatment osteoporosis have instant effect, cure rate high, have no side effect, the advantage of safe ready, there is the effect of comparatively significant lubricating joint, strengthening the tendons and bones, significantly improve the immunity of human body simultaneously, the clinical treatment of osteoporosis can be widely used in.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
The processing step of process for preparing medicine of the present invention is:
(1) Ramulus et Folium Psychotriae Serpentis, Carnis Coturnicis japonicae, Radix calophylli membranacei, Mytilus, Herba Sambuci Adnatae, Radix Flemingiae Philippinensis, Herba Hoyae lancilimbae and Radix Glycyrrhizae are put into container, first add 10-15 times amount distilled water immersion after 4-5 hour, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge extractive liquid, filters, obtains filtrate for subsequent use;
(2) Radix seu Caulis Verntilaginis Leiocarpae, Parmelia saxatilis Ach. and Caulis Piperis Boehmeriaefolii are immersed 10 times amount volumetric concentration 70% alcohol solution dipping 4 hours, heating extraction, filter, after leaving standstill, reclaiming ethanol and being concentrated into 60 DEG C of relative densities is that the thick paste of 1.12-1.15 is for subsequent use;
(3) by Herba Thesii, Cortex Cinnamomi Burmannii and Herba Pyrolae microwave drying, grind into powder, cross 100 order fine powders, for subsequent use;
(4) Radix Angelicae Sinensis is used yellow wine uniform spraying, slightly vexed, put in pot and fry with low baking temperature, take out, cool, grind into powder, cross 160 order fine powders, for subsequent use;
(5) Caulis et Folium Brassicae capitatae is twisted juice, filter impurity, stays juice, for subsequent use;
(6) by filtrate obtained for step (1)-(5), thick paste, fine powder and juice mixing, make medicine, be the medicine being used for the treatment of osteoporosis of the present invention.
Usage and dosage: oral, every day 3 times, each 27 days is a course for the treatment of, and the lighter can fully recover 2 to 4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of osteoporosis, select the routine clinical observation of patients with osteoporosis 100 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random, treatment group 50 example, wherein male 25 example, women 25 example, age 35-80 year, 35 years old mean age, course of disease 1-26; Matched group 50 example, wherein male 25 example, women 25 example, age 38-76 year, 38 years old mean age, course of disease course of disease 1-20.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes medicine of the present invention, every day 3 times, each 2, and warm water delivery service in half an hour after meal 7 days is a course for the treatment of, and taking 2 to 4 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes XIANLING GUBAO JIAONANG, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: the transference cures such as bone destruction, heterotopic calcification, textured bone shortening, lumbus sacrum pain, microcirculation disturbance, popularity osteoporosis, thoracic vertebra are lopsided, unable, osteodynia, compression-type fracture, physical recovery is normal.
(2) effective: above-mentioned symptom is alleviated to some extent.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 38 examples, effective 9 examples, invalid 3 examples, cure rate is
76%, total effective rate 94%.
Cure 10 examples in matched group, effective 19 examples, invalid 21 examples, cure rate is 20%, total effective rate 58%.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
5, model case citing:
(1), Tang, man, 68 years old, retired worker, Zhejiang Huzhou people.More than 20 years of patient's lumbago, time light time heavy, nearly one month aggravation.Lumbago unbearably, and to two hip and numbness of lower limbs pain, can not stand for a long time sitting and normal waking activity, be afraid of cold obviously, and right lower limb is obvious, sleeps not good enough by waist lower limb.Once took Chinese medicine and western medicine and acupuncture and moxibustion therapy, when stopping treatment, the state of an illness recurs again.Therefore seek medical advice.Lumbar X mating plate shows: lumbar physiological-curvature straightens, narrowing of intervertebral space.Be diagnosed as: lumbar vertebrae bone osteoporosis.After take 4 courses for the treatment of of medicine of the present invention after, pain disappears, and suffering limb activity freely, is followed up a case by regular visits to and do not recurred, and thoroughly cures.
(2), Hao, man, 59 years old, machine-operated retired cadre, Huainan, Anhui people.Patient suffers from osteoporosis for many years, and before treatment, cardinal symptom is lumbago, to sit and pain is bent obviously in front and back to rise, adopt through Shuo Jia hospital inject, the methods such as acupuncture, massage of forcing on, the state of an illness is not felt any better.For further diagnosis and treatment, to our hospital.After taking 2 courses for the treatment of of medicine of the present invention, pick body, continue to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom disappears, and follows up a case by regular visits to and does not recur, thoroughly cure.
(3), Wei, female, 70 years old, retired professor, Quanzhou, Fujian people.For many years, recurrent exerbation, increases the weight of patient's lumbago pain for nearly 1 month, can not normal waking activity when standing, and waist is ached unbearably, two numbness of lower limbs pain, and waist was ached and was afraid of cold night, and chronic insomnia, urine frequently color is clear, and stool is normal.Show through X-ray: lumbar curvature straightens, narrowing of intervertebral space.Be diagnosed as: senile osteoporosis.After taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom takes a turn for the better, and after continuing to take 2 courses for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur.
(4), Liu, man, 62 years old, peasant, yiyang, hunan people.Patient is interrupted lumbago and backache 5 years and institute goes to a doctor in me, suffers from chronic pancreatitis and chronic diarrheal disease 3 years, being diagnosed as osteoporosis, once accepting oral analgesic treatment, not taking a favorable turn by checking, rear to our hospital.After take 1 course for the treatment of of medicine of the present invention after, pain relief, continue to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom all disappears, and follows up a case by regular visits to and does not recur, and thoroughly cures.
(5), fourth, man, 58 years old, retired worker, the new village people in Henan.Patient suffers from lumbago and skelalgia more than 5 years, recently increases the weight of, to our hospital, is diagnosed as osteoporosis.After take 2 courses for the treatment of of medicine of the present invention after, above-mentioned symptom takes a turn for the better, and after continuing to take 2 courses for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur.
(6), Shen, female, 55 years old, certain enterprise retired veteran cadre, Shantou, Guangdong people.Patient suffers from the lumbago and skelalgia several years, recently increases the weight of, and through local hospital X-ray examination, is diagnosed as serious osteoporosis, remaining the bimester of adopting injection Calcitonin, oral side Trane etc. to treat by hospital, does not feel any better.After take 3 courses for the treatment of of medicine of the present invention, pick body, after continuing to take 2 courses for the treatment of of medicine of the present invention, health is fully recovered, and follows up a case by regular visits to and does not recur.
Claims (5)
1. be used for the treatment of a medicine for osteoporosis, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Ramulus et Folium Psychotriae Serpentis 24-48 part Carnis Coturnicis japonicae 22-47 part Radix calophylli membranacei 20-44 part Radix seu Caulis Verntilaginis Leiocarpae 20-44 part
Herba Thesii 17-42 part Mytilus 16-40 part Herba Sambuci Adnatae 16-40 part Radix Flemingiae Philippinensis 15-35 part
Parmelia saxatilis Ach. 15-35 part Herba Hoyae lancilimbae 14-32 part Radix Angelicae Sinensis 14-32 part Caulis Piperis Boehmeriaefolii 12-30 part
Caulis et Folium Brassicae capitatae 12-27 part Cortex Cinnamomi Burmannii 11-24 part Radix Glycyrrhizae 10-22 part Herba Pyrolae 7-17 part.
2. a kind of medicine being used for the treatment of osteoporosis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Ramulus et Folium Psychotriae Serpentis 42 portions of Carnis Coturnicis japonicaes 40 parts of Radix calophylli membranacei 38 parts of Radix seu Caulis Verntilaginis Leiocarpae 38 parts
Herba Thesii 35 portions of Mytilus 34 parts of Herba Sambuci Adnatae 34 parts of Radix Flemingiae Philippinensiss 30 parts
Parmelia saxatilis Ach. 30 parts of Herba Hoyae lancilimbaes 27 parts of Radix Angelicae Sinensis 27 parts of Caulis Piperis Boehmeriaefoliis 25 parts
Caulis et Folium Brassicae capitatae 23 parts of Cortex Cinnamomi Burmanniis 20 portions of Radix Glycyrrhizaes 19 portions of Herba Pyrolaes 14 parts.
3. a kind of medicine being used for the treatment of osteoporosis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Ramulus et Folium Psychotriae Serpentis 36 portions of Carnis Coturnicis japonicaes 34 parts of Radix calophylli membranacei 32 parts of Radix seu Caulis Verntilaginis Leiocarpae 32 parts
Herba Thesii 29 portions of Mytilus 28 parts of Herba Sambuci Adnatae 28 parts of Radix Flemingiae Philippinensiss 25 parts
Parmelia saxatilis Ach. 25 parts of Herba Hoyae lancilimbaes 23 parts of Radix Angelicae Sinensis 23 parts of Caulis Piperis Boehmeriaefoliis 21 parts
Caulis et Folium Brassicae capitatae 20 parts of Cortex Cinnamomi Burmanniis 17 portions of Radix Glycyrrhizaes 16 portions of Herba Pyrolaes 12 parts.
4. a kind of medicine being used for the treatment of osteoporosis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Ramulus et Folium Psychotriae Serpentis 30 portions of Carnis Coturnicis japonicaes 28 parts of Radix calophylli membranacei 26 parts of Radix seu Caulis Verntilaginis Leiocarpae 26 parts
Herba Thesii 23 portions of Mytilus 22 parts of Herba Sambuci Adnatae 22 parts of Radix Flemingiae Philippinensiss 20 parts
Parmelia saxatilis Ach. 20 parts of Herba Hoyae lancilimbaes 19 parts of Radix Angelicae Sinensis 19 parts of Caulis Piperis Boehmeriaefoliis 17 parts
Caulis et Folium Brassicae capitatae 17 parts of Cortex Cinnamomi Burmanniis 14 portions of Radix Glycyrrhizaes 13 portions of Herba Pyrolaes 10 parts.
5. the preparation method being used for the treatment of the medicine of osteoporosis as described in claim 1-5, is characterized in that: comprise following processing step:
(1) Ramulus et Folium Psychotriae Serpentis, Carnis Coturnicis japonicae, Radix calophylli membranacei, Mytilus, Herba Sambuci Adnatae, Radix Flemingiae Philippinensis, Herba Hoyae lancilimbae and Radix Glycyrrhizae are put into container, first add 10-15 times amount distilled water immersion after 4-5 hour, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge extractive liquid, filters, obtains filtrate for subsequent use;
(2) Radix seu Caulis Verntilaginis Leiocarpae, Parmelia saxatilis Ach. and Caulis Piperis Boehmeriaefolii are immersed 10 times amount volumetric concentration 70% alcohol solution dipping 4 hours, heating extraction, filter, after leaving standstill, reclaiming ethanol and being concentrated into 60 DEG C of relative densities is that the thick paste of 1.12-1.15 is for subsequent use;
(3) by Herba Thesii, Cortex Cinnamomi Burmannii and Herba Pyrolae microwave drying, grind into powder, cross 100 order fine powders, for subsequent use;
(4) Radix Angelicae Sinensis is used yellow wine uniform spraying, slightly vexed, put in pot and fry with low baking temperature, take out, cool, grind into powder, cross 160 order fine powders, for subsequent use;
(5) Caulis et Folium Brassicae capitatae is twisted juice, filter impurity, stays juice, for subsequent use;
(6) by filtrate obtained for step (1)-(5), thick paste, fine powder and juice mixing, make medicine, be the described medicine being used for the treatment of osteoporosis.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105168272A (en) * | 2015-09-29 | 2015-12-23 | 罗奕珺 | Application of pharmaceutical composition to preparation of drug for treating osteoporosis |
| CN109045079A (en) * | 2018-09-04 | 2018-12-21 | 深圳前海九华国际供应链管理有限公司 | A kind of Thesium chinese extract powder is used for the purposes of union |
| CN109045080A (en) * | 2018-09-04 | 2018-12-21 | 深圳前海九华国际供应链管理有限公司 | A kind of Thesium chinese extract powder is used to treat the purposes of osteoporosis |
| CN112933129A (en) * | 2021-04-29 | 2021-06-11 | 云南中医药大学 | Application of scandent scab extract |
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| CN103405509A (en) * | 2013-07-30 | 2013-11-27 | 河南省洛阳正骨医院 | Cancellous bone-benefiting prescription for treating osteoporosis and preparation technology of |
| CN103860905A (en) * | 2014-03-14 | 2014-06-18 | 李群 | Traditional Chinese medicine preparation for treating osteoporosis |
| CN104001004A (en) * | 2014-06-16 | 2014-08-27 | 徐艳 | Traditional Chinese medicine composition for curing fractures and osteoporosis and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103405509A (en) * | 2013-07-30 | 2013-11-27 | 河南省洛阳正骨医院 | Cancellous bone-benefiting prescription for treating osteoporosis and preparation technology of |
| CN103860905A (en) * | 2014-03-14 | 2014-06-18 | 李群 | Traditional Chinese medicine preparation for treating osteoporosis |
| CN104001004A (en) * | 2014-06-16 | 2014-08-27 | 徐艳 | Traditional Chinese medicine composition for curing fractures and osteoporosis and preparation method and application thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105168272A (en) * | 2015-09-29 | 2015-12-23 | 罗奕珺 | Application of pharmaceutical composition to preparation of drug for treating osteoporosis |
| CN109045079A (en) * | 2018-09-04 | 2018-12-21 | 深圳前海九华国际供应链管理有限公司 | A kind of Thesium chinese extract powder is used for the purposes of union |
| CN109045080A (en) * | 2018-09-04 | 2018-12-21 | 深圳前海九华国际供应链管理有限公司 | A kind of Thesium chinese extract powder is used to treat the purposes of osteoporosis |
| CN112933129A (en) * | 2021-04-29 | 2021-06-11 | 云南中医药大学 | Application of scandent scab extract |
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Application publication date: 20150325 |