CN105168640A - Medicament for treating protrusion of lumbar intervertebral disc and preparation method of medicament - Google Patents
Medicament for treating protrusion of lumbar intervertebral disc and preparation method of medicament Download PDFInfo
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Abstract
The invention discloses a medicament for treating protrusion of lumbar intervertebral disc and a preparation method of the medicament, which belong to the field of traditional Chinese medicines. The effective components of the medicament are prepared from the following raw materials: thesium chinensis, tetrastigma planicaule, psoralea corylifolia, fiveleaf akebia fruit, melica scabrosa, angelica dahurica, bark of corkywing euonymus, ficus pumila linn, pleurotus ostreatus, leaf and twig of nakedflower beautyberry, grey rat snake, erythrina bark, sophora twig, excoecaria cochinchinensis, serrate chloranthus and lygodium japonicum. The medicinal materials for preparing the medicament are properly matched; the medicament accords with the theory of traditional Chinese medicine and modern medicine, has the efficacy of activating blood circulation to eliminate swelling, dissipating blood stasis and relieving pain, and expelling wind and removing cold, and has a unique curative effect for treating the protrusion of lumbar intervertebral disc caused by various symptoms; the medicament has the advantages of obvious curative effect, convenience in administration, no relapse after curing, safety, reliability, no toxic or side effects and lower cost; in addition, the medicament can achieve the aim of treating both manifestation and root cause of disease, and is worthy of being widely popularized and applied.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and preparation method for the treatment of prolapse of lumbar intervertebral disc.
Background technology
Prolapse of lumbar intervertebral disc is one of comparatively common illness, mainly because lumbar intervertebral disc each several part is as vertebral pulp, fibrous ring and cartilaginous lamina, especially vertebral pulp, after having degenerative change in various degree, under the effect of external force factor, the Anular disruption of intervertebral disc, nucleus pulposus protrudes from rear or intraspinal tube from part of breaking, cause adjacent ridge nerve root stimulated or oppress, thus produce flank pain, a series of clinical symptoms such as side lower limb or two numbness of lower limbs, pain.Prolapse of lumbar intervertebral disc is the highest with waist 4-5, waist 5-sacrum 1 sickness rate, accounts for 95%.
Prolapse of lumbar intervertebral disc is due to lumbar degenerative disc, Anular disruption, a series of clinical symptoms that Nucleus pulposus stimulates or pressuring neural root, cauda equina nerve show and sign, be commonly called as " waist dash forward disease ", be clinical commonly encountered diseases and cause the topmost reason of lumbago and skelalgia, the normal live and work of patient of giving brings many miseries, even causes deformity, disability.Intervertebral disc lacks blood circulation gradually after growing up, and repair ability is poor.On the basis of above-mentioned factor effect, certain can cause intervertebral disc bear the risk factor that pressure raises suddenly, the poor vertebral pulp of elasticity namely may being made through becoming not too tough and tensile fibrous ring, causing Nucleus pulposus.The regression main manifestations of vertebral pulp is the reduction of water content, and vertebra can be caused to save unstability because of dehydration, the pathological change among a small circle such as to loosen; The regression main manifestations of fibrous ring is the reduction of tough and tensile degree, and prolonged and repeated external force causes slight damage, has increased the weight of the degree of regression.
At present, medicine for treatment prolapse of lumbar intervertebral disc is a lot, and Western medicine uses injectable drug treatment, though there is certain curative effect, but treatment cycle is long, dependency is strong, and after drug withdrawal easily repeatedly, and Chinese traditional treatment, then effect is not ideal, and easily recur, therapeutic effect is not good, needs research and development one to treat the better medicine of prolapse of lumbar intervertebral disc.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of prolapse of lumbar intervertebral disc; Selected by medicine of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of promoting blood circulation and detumescence, eliminating stasis to stop pain, expelling wind and cold, to the prolapse of lumbar intervertebral disc that the various symptom for the treatment of causes, there is unique curative effect, and it is evident in efficacy, taking convenience, non-relapse after healing, safe and reliable, without any side effects, cost is lower, can reach the object for the treatment of both the principal and secondary aspects of a disease, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for prolapse of lumbar intervertebral disc, raw material composition and the parts by weight of making described effective ingredient are:
Herba Thesii 22 ~ 40 parts of Caulis et Radix Tetrastigmatis Planicaulis 21 ~ 39 parts of Fructus Psoraleaes 21 ~ 39 parts of Fructus Akebiaes 20 ~ 38 parts
Herba rutae 19 ~ 37 parts of Radixs Angelicae Dahuricae 19 ~ 37 parts of Cortex Euonymi phellomaniss 18 ~ 36 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 17 ~ 35 parts
To pick up the ears 17 ~ 35 parts of Folium et Ramulus Callicarpae nudiflorae, 16 ~ 34 parts of Ptyas Korross, 16 ~ 34 parts of Cortex erythrinaes 14 ~ 32 parts
Rumalus sophorae 12 ~ 30 parts of Herba Excoecariae cochinchinensis 10 ~ 29 parts of Radix Chloranthi Serrati 10 ~ 29 parts of Spora Lygodii grass 9 ~ 27 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Herba Thesii 25 ~ 37 parts of Caulis et Radix Tetrastigmatis Planicaulis 24 ~ 36 parts of Fructus Psoraleaes 24 ~ 36 parts of Fructus Akebiaes 23 ~ 35 parts
Herba rutae 22 ~ 34 parts of Radixs Angelicae Dahuricae 22 ~ 34 parts of Cortex Euonymi phellomaniss 21 ~ 33 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 20 ~ 32 parts
To pick up the ears 20 ~ 32 parts of Folium et Ramulus Callicarpae nudiflorae, 19 ~ 31 parts of Ptyas Korross, 19 ~ 31 parts of Cortex erythrinaes 17 ~ 29 parts
Rumalus sophorae 15 ~ 27 parts of Herba Excoecariae cochinchinensis 14 ~ 26 parts of Radix Chloranthi Serrati 14 ~ 26 parts of Spora Lygodii grass 12 ~ 24 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Herba Thesii 28 ~ 34 parts of Caulis et Radix Tetrastigmatis Planicaulis 27 ~ 33 parts of Fructus Psoraleaes 27 ~ 33 parts of Fructus Akebiaes 26 ~ 32 parts
Herba rutae 25 ~ 31 parts of Radixs Angelicae Dahuricae 25 ~ 31 parts of Cortex Euonymi phellomaniss 24 ~ 30 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 23 ~ 29 parts
To pick up the ears 23 ~ 29 parts of Folium et Ramulus Callicarpae nudiflorae, 22 ~ 28 parts of Ptyas Korross, 22 ~ 28 parts of Cortex erythrinaes 20 ~ 26 parts
Rumalus sophorae 18 ~ 24 parts of Herba Excoecariae cochinchinensis 17 ~ 23 parts of Radix Chloranthi Serrati 17 ~ 23 parts of Spora Lygodii grass 15 ~ 21 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Herba Thesii 31 parts of Caulis et Radix Tetrastigmatis Planicaulis 30 parts of Fructus Psoraleaes 30 parts of Fructus Akebiaes 29 parts
Herba rutae 28 parts of Radixs Angelicae Dahuricae 28 parts of Cortex Euonymi phellomaniss 27 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 26 parts
To pick up the ears 26 parts of Folium et Ramulus Callicarpae nudiflorae, 25 parts of Ptyas Korross, 25 parts of Cortex erythrinaes 23 parts
Rumalus sophorae 21 parts of Herba Excoecariae cochinchinensis 20 parts of Radix Chloranthi Serrati 20 parts of Spora Lygodii grass 18 parts.
Treat a preparation method for the medicine of prolapse of lumbar intervertebral disc, comprise following processing step:
(1) Herba Thesii, Caulis et Radix Tetrastigmatis Planicaulis, Fructus Akebiae, Cortex Euonymi phellomanis, Ptyas Korros and Cortex erythrinae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(2) by Fructus Psoraleae, pick up the ears, Folium et Ramulus Callicarpae nudiflorae, Herba Excoecariae cochinchinensis and Spora Lygodii grass clean, put into container, add the distilled water of 8 ~ 10 times amount, soaks after 5 ~ 6 hours, boil 3 ~ 4 hours, extraction; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(3) Herba rutae and Caulis fici pumilae (Fructus Fici Pumilae) are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Radix Angelicae Dahuricae, Rumalus sophorae and Radix Chloranthi Serrati are put into container, carry out pulverization process, grind into powder, 180 object fine powders must be, for subsequent use;
(5) thick paste, juice and fine powder obtained by above-mentioned steps (1) ~ (4) are made tablet, obtain the medicine of described treatment prolapse of lumbar intervertebral disc.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Thesii: acrid in the mouth, hardship, puckery, property is put down.Heat-clearing and toxic substances removing, separates administration.For enteritis, lung abscess, tonsillitis, middle administration, acute mastitis, tuberculous lymphadenitis, acute cystitis, upper respiratory tract infection, lumbago due to renal deficiency, dizzy, seminal emission, spermatorrhea." Guizhou side among the people medicine collection " carries: " control dizzy weak, lumbago, seminal emission, spermatorrhea.”
Caulis et Radix Tetrastigmatis Planicaulis: sour in the mouth, puckery, warm in nature, GUIXIN, Liver Channel.To dispel the wind removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.Main air pain of dampness syndrome, lumbar muscle strain, apoplectic hemiplegia, traumatic injury.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " dispeiling pathogenic wind and removing dampness.Treating rheumatic lumbago and skelalgia, hemiplegia, rheumatism of muscles pain.”
Fructus Psoraleae: acrid in the mouth, hardship, warm in nature; Return kidney, the heart, spleen, stomach, lung meridian.Reinforcing the kidney and supporting YANG, helping inspiration to relieve asthma, warming spleen and stopping diarrha.Main insufficiency of kidney-YANG, below element deficiency and cold, chills and pain of the waist and kness, sexual impotence essence, frequent micturition, the enuresis, failure of the kidney in receiving QI, dyspnea due to deficiency is more than, asthenia of both the spleen and kidney, stool chronic diarrhea, vitiligo, alopecia areata, psoriasis." beautiful Chinese catalpa medicine solution " carry: " warm water and soil, digestion diet, rise reach taste, convergence lingering diarrhea, seminal emission, leukorrhagia, drown many, just slide all cards.”
Fructus Akebiae: sweet in the mouth, cold in nature, return liver, stomach, urinary bladder channel.Liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis.Cure mainly stomachache due to hyperactive liver-QI attacking the stomach, gastric heat food is slow-witted, excessive thirst, also Hakuri, lumbago, hypochondriac pain, hernia, cave warp, and uterus drops." Shaanxi Chinese herbal medicine " carries: " Shugan Yishen, invigorating the spleen and regulating the stomach.Control dyspepsia, stomachache, dysentery, hernia, uterus drops.”
Herba rutae: acrid in the mouth, micro-hardship, cold in nature; Return lung, kidney, liver, heart channel.Expelling wind and clearing away heat, promoting blood circulation to remove blood stasis, subduing swelling and detoxicating.Main cold, fever, infantile hyperpyrexia infantile convulsion, dysmenorrhea, amenorrhea, traumatic injury, pathopyretic ulcer, infantile eczema, snake bite and insect sting." Nanning City's medicine will " carries: " bring down a fever and dispel the wind, inducing diuresis to remove edema.Control fever of children infantile convulsion, rheumatic ostalgia.”
The Radix Angelicae Dahuricae, acrid in the mouth, warm in nature; Attach to the lung and stomach meridians.Expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.Profit blood vessels, expelling wind and cold, eliminating dampness and dredging channels, is widely used in the treatment of the diseases such as soft tissue contusion, hyperosteogeny, muscular strain, rheumatic myositis, fracture, costal chondritis, scapulohumeral periarthritis, intercostal neuralgia.The Radix Angelicae Dahuricae all has inhibitory action to escherichia coli, dysentery bacterium, Bacillus proteus, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, vibrio cholera, Bacillus tuberculosis etc.
Cortex Euonymi phellomanis: cold in nature, bitter in the mouth; Enter liver, lung two warp.Removing blood stasis falls tire, regulating menstruation Radix Dipsaci.Control puerperal abdonimal pain, metrorrhagia hematochezia, rheumatalgia.
Caulis fici pumilae (Fructus Fici Pumilae): sour in the mouth, cool in nature.Expelling wind and removing dampness, promoting blood circulation and detoxication.Control phoenix pain of dampness syndrome, dysentery, gonorrhea, traumatic injury, carbuncle furuncle." Hunan medicine will " carries: " heat-clearing and toxic substances removing, damp eliminating diuresis.Control filaricide, traumatic injury, lumbago, hematodiarrhoea, watery diarrhea, pyretic stranguria, tripe flatulence falls.”
Pick up the ears: acrid in the mouth, sweet, warm in nature; Return liver, kidney channel.Wind-evil dispelling and cold-evil expelling, relaxing muscles and tendons and activating QI and blood in the collateral, kidney invigorating and YANG supporting.Main lumbago and skelalgia, numb hand and foot, grain does not relax, impotence and seminal emission, weakness of the waist and knees." Xinhua's book on Chinese herbal medicine outline " carries: " have the effect such as relaxing muscles and tendons and activating QI and blood in the collateral, wind-evil dispelling and cold-evil expelling, be used for tonic.”
Folium et Ramulus Callicarpae nudiflorae: micro-hardship, property is put down.Hemostasis, antiinflammatory, blood stasis dispelling, pain relieving.That controls that pneumorrhagia type leptospirosis, pulmonary tuberculosis, lung abscess, lobar pneumonia etc. cause is hemorrhage, the upper gastrointestinal hemorrhage that Peptic Ulcers etc. cause, thrombocytopenic purpura, hematuria, wound hemorrhage, influenza, burn, suppurative skin ulcer, cervical erosion, traumatic injury, rheumatalgia." south of the Five Ridges gather medicinal herbs record " carries: " decoct washing traumatic injury wound, can eliminating blood stasis to promote regeneration of blood.As swelling due to wind, leaf is decocted washing, get its stalk and lean pork decoction, can wind dispelling detumescence.”
Ptyas Korros: sweet in the mouth, salty, property is put down; Return liver, kidney channel.Wind-expelling pain-stopping, relaxing muscles and tendons and activating QI and blood in the collateral.Main air arthralgia chiefly caused by damp pathogen is demonstrate,proved, waist and leg ache, numb limbs and tense tendons, and half body is fried then, poliomyelitis.
Cortex erythrinae: bitter in the mouth, property is put down; Return liver, kidney channel.Wind-damp dispelling, channels sootheing and network vessel quickening.For rheumatic numbness, waist hamstring bone pain, traumatic injury; Various stubborn dermatitis is controlled in external." Haiyao Bencao, Oversea Materia Medica " carries: " main waist foot is unsuccessful, insensitive impediment lower limb knee joint pain, cholera, red white dysentery, dysentery, scabies.”
Rumalus sophorae: bitter in the mouth, property is put down; GUIXIN, Liver Channel.Dissipating blood stasis stops blooding, heat clearing and damp drying, wind dispelling insecticide.Main metrorrhagia, leucorrhea with red and white discharge, hemorrhoid, scrotum pruritus due to damp pathogen, pained, conjunctival congestion, scabies." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " wash skin mange, remove the wind of skin pruritus.”
Herba Excoecariae cochinchinensis: acrid in the mouth, micro-hardship, property is put down, slightly poisonous; Return Liver Channel.Dredge the meridian passage, pain relieving.Cure mainly measles, parotitis, tonsillitis, angina pectoris, renal colic, lumbar muscle strain." Xinhua's book on Chinese herbal medicine outline " carries: " dredge the meridian passage, pain relieving, for measles, parotitis, tonsillitis, angina pectoris, renal colic; Lumbar muscle strain.”
Radix Chloranthi Serrati: acrid in the mouth, warm in nature, poisonous; Return Liver Channel.Relaxing muscles and tendons and activating QI and blood in the collateral, wind-expelling pain-stopping, subduing swelling and detoxicating.For traumatic injury, lumbago, skelalgia of rheumatism, furuncle swelling toxin, venom." Zhejiang conventional medical herbs among the people " carries: " removing blood stasis and activating blood flow, anti-inflammation.Control and get injured by a fall, sprain, fracture, furuncle and phyma, amenorrhea.”
Spora Lygodii grass: sweet in the mouth, micro-hardship, cold in nature.Heat clearing away, dampness removing, relaxing muscles and tendons and activating QI and blood in the collateral, hemostasis.Cure mainly urinary tract infection, lithangiuria, oedema due to nephritis, hepatitis, dysentery, conjunctival congestion and swelling pain, rheumatic arthralgia, muscles and bones is numb, injury and bone fracture, traumatic hemorrhage.
The present invention compared with prior art, has following beneficial effect:
Selected by medicine of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of promoting blood circulation and detumescence, eliminating stasis to stop pain, expelling wind and cold, to the prolapse of lumbar intervertebral disc that the various symptom for the treatment of causes, there is unique curative effect, and it is evident in efficacy, taking convenience, non-relapse after healing, safe and reliable, without any side effects, cost is lower, can reach the object for the treatment of both the principal and secondary aspects of a disease, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Herba Thesii 37g Caulis et Radix Tetrastigmatis Planicaulis 36g Fructus Psoraleae 36g Fructus Akebiae 35g
Herba rutae 34g Radix Angelicae Dahuricae 34g Cortex Euonymi phellomanis 33g Caulis fici pumilae (Fructus Fici Pumilae) 32g
Pick up the ears 32g Folium et Ramulus Callicarpae nudiflorae 31g Ptyas Korros 31g Cortex erythrinae 29g
Rumalus sophorae 27g Herba Excoecariae cochinchinensis 26g Radix Chloranthi Serrati 26g Spora Lygodii grass 24g.
Treat a preparation method for the medicine of prolapse of lumbar intervertebral disc, comprise following processing step:
(1) Herba Thesii, Caulis et Radix Tetrastigmatis Planicaulis, Fructus Akebiae, Cortex Euonymi phellomanis, Ptyas Korros and Cortex erythrinae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(2) by Fructus Psoraleae, pick up the ears, Folium et Ramulus Callicarpae nudiflorae, Herba Excoecariae cochinchinensis and Spora Lygodii grass clean, put into container, add the distilled water of 8 ~ 10 times amount, soaks after 5 ~ 6 hours, boil 3 ~ 4 hours, extraction; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(3) Herba rutae and Caulis fici pumilae (Fructus Fici Pumilae) are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Radix Angelicae Dahuricae, Rumalus sophorae and Radix Chloranthi Serrati are put into container, carry out pulverization process, grind into powder, 180 object fine powders must be, for subsequent use;
(5) thick paste, juice and fine powder obtained by above-mentioned steps (1) ~ (4) are made tablet, obtain the medicine of described treatment prolapse of lumbar intervertebral disc.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 3 (every sheet 0.5g), warm water delivery service after meal; Within 8 days, be 1 course for the treatment of, 3 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
Herba Thesii 34g Caulis et Radix Tetrastigmatis Planicaulis 33g Fructus Psoraleae 33g Fructus Akebiae 32g
Herba rutae 31g Radix Angelicae Dahuricae 31g Cortex Euonymi phellomanis 30g Caulis fici pumilae (Fructus Fici Pumilae) 29g
Pick up the ears 29g Folium et Ramulus Callicarpae nudiflorae 28g Ptyas Korros 28g Cortex erythrinae 26g
Rumalus sophorae 24g Herba Excoecariae cochinchinensis 23g Radix Chloranthi Serrati 23g Spora Lygodii grass 21g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
Herba Thesii 31g Caulis et Radix Tetrastigmatis Planicaulis 30g Fructus Psoraleae 30g Fructus Akebiae 29g
Herba rutae 28g Radix Angelicae Dahuricae 28g Cortex Euonymi phellomanis 27g Caulis fici pumilae (Fructus Fici Pumilae) 26g
Pick up the ears 26g Folium et Ramulus Callicarpae nudiflorae 25g Ptyas Korros 25g Cortex erythrinae 23g
Rumalus sophorae 21g Herba Excoecariae cochinchinensis 20g Radix Chloranthi Serrati 20g Spora Lygodii grass 18g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
Herba Thesii 28g Caulis et Radix Tetrastigmatis Planicaulis 27g Fructus Psoraleae 27g Fructus Akebiae 26g
Herba rutae 25g Radix Angelicae Dahuricae 25g Cortex Euonymi phellomanis 24g Caulis fici pumilae (Fructus Fici Pumilae) 23g
Pick up the ears 23g Folium et Ramulus Callicarpae nudiflorae 22g Ptyas Korros 22g Cortex erythrinae 20g
Rumalus sophorae 18g Herba Excoecariae cochinchinensis 17g Radix Chloranthi Serrati 17g Spora Lygodii grass 15g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
Herba Thesii 25g Caulis et Radix Tetrastigmatis Planicaulis 24g Fructus Psoraleae 24g Fructus Akebiae 23g
Herba rutae 22g Radix Angelicae Dahuricae 22g Cortex Euonymi phellomanis 21g Caulis fici pumilae (Fructus Fici Pumilae) 20g
Pick up the ears 20g Folium et Ramulus Callicarpae nudiflorae 19g Ptyas Korros 19g Cortex erythrinae 17g
Rumalus sophorae 15g Herba Excoecariae cochinchinensis 14g Radix Chloranthi Serrati 14g Spora Lygodii grass 12g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of prolapse of lumbar intervertebral disc, select the routine clinical observation of patients with lumbar disc herniation 310 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 155 example, wherein male 77 example, women 78 example, 39 ~ 74 years old age, 56.5 years old mean age, average course of disease 10 years; Matched group 155 example, wherein male 78 example, women 77 example, 38 ~ 73 years old age, 56.5 years old mean age, average course of disease 10 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 2 times, each 1 time sooner or later, each 3 (every sheet 0.5g), warm water delivery service after meal; Within 8 days, be 1 course for the treatment of, 3 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes Dicolfanac Sodium Sustained Release Tablets, oral, a 0.1g (1), 1 time on the one, or follows the doctor's advice, and with warm water delivery service after dinner, needs full wafer to swallow, does not break into pieces or chew.
3, efficacy determination:
(1) cure: prolapse of lumbar intervertebral disc shape all disappears, and physical recovery is normal.
(2) effective: prolapse of lumbar intervertebral disc shape obviously alleviates, and health takes a turn for the better to some extent.
(3) effective: prolapse of lumbar intervertebral disc shape alleviates to some extent, and health is clearly better.
(4) invalid: by treating rear prolapse of lumbar intervertebral disc shape without alleviating or increasing the weight of.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, desolate certain, man, 41 years old, people from Wansheng District, Chongqing.Patient's CT examination prompts for prolapse of lumbar intervertebral disc: L5-S1 annuler bulge the last outstanding about 8 millimeters left, dural sac and seat nervus lateralis root pressurized obvious.First take medicine and to no effect now do expectant treatment afterwards, lie up, take medicine, protect with waistline, the state of an illness takes a turn for the better to some extent but has no recovery from illness.Rear patient starts to take Drug therapy of the present invention, and after taking 1 course for the treatment of, symptom is alleviated to some extent, and after continuing to take 3 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to so far without recurrence.
2, Deng, man, 58 years old, ShenZhen,GuangDong people.Patient suffers from prolapse of lumbar intervertebral disc more than 6 years, cannot walk, take a turn for the better after expectant treatment, occurred again that the right side had a pain in the leg pain afterwards, can not walk for a long time, sleep in evening sometimes can not recumbency, right lower limb is stretched not straight, massages, takes medicine, has an injection all to no effect, give Drug therapy of the present invention, after taking 2 courses for the treatment of, symptom obviously alleviates, and after continuing to take 2 courses for the treatment of, symptom all disappears, recovery from illness, follows up a case by regular visits to after half a year without recurrence.
3, Fu, female, 47 years old, people from Chengdu, Sichuan.There is right lower extremity pain and pain and numbness in patient, tired, sitting postemphasis, alleviates after having a rest, remove hospital admission after ill, CT examination prompts for prolapse of lumbar intervertebral disc, after Drug therapy, pain is alleviated to some extent, and after drug withdrawal, just recurrence, has no improvement, through friend recommendation, to our hospital, give Drug therapy of the present invention, after taking 2 courses for the treatment of, symptom obviously alleviates, after continuing to take 2 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to after 2 years without recurrence.
4, Zeng, female, 52 years old, people from Nanjing.It is prominent for many years that patient suffers from lumbar intervertebral disc, in recent years increases the weight of year by year, cannot walk, occur again after stopping treatment that the right side has a pain in the leg bitterly, can not walk for a long time, right lower limb stretches the symptoms such as not straight, massage, take medicine, have an injection all to no effect, recommend through doctor, take medicine of the present invention, take 2 courses for the treatment of, patient's freedom of movement, after continuing to take 1 course for the treatment of, transference cure, recovery from illness, recurrence of following up a case by regular visits to that so far there are no.
5, Lu, man, 63 years old, people from Xi'an, Shaanxi.Patient suffers from prolapse of lumbar intervertebral disc 10 years, this year especially severe, main manifestations is lumbar spinal stenosis, stand difficulty of walking, compressing leg is neural, cause have a pain in the leg, numb, recommend through doctor, take invention Drug therapy, after taking 2 courses for the treatment of, symptom is clearly better, after taking 4 courses for the treatment of, symptom all disappears, recovery from illness, follows up a case by regular visits to without recurrence after 1 year.
6, Jiang, female, 67 years old, people from Xuchang, Henan.Patient suffers from prolapse of lumbar intervertebral disc sciatic nerve crush, and location picture shows that lumbar physiological-curvature exists, and each intervertebral space is without narrowing, part vertebral body hyperosteogeny, dural sac and two nervus lateralis are without pressurized, and ligamenta flava is not thick, canalis spinalis has no narrow, and bilateral psoas major form density nature, gives Drug therapy of the present invention, after taking 2 courses for the treatment of, symptom obviously alleviates, after taking 3 courses for the treatment of, and transference cure, recovery from illness, follows up a case by regular visits to so far without recurrence.
Claims (5)
1. treat a medicine for prolapse of lumbar intervertebral disc, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Thesii 22 ~ 40 parts of Caulis et Radix Tetrastigmatis Planicaulis 21 ~ 39 parts of Fructus Psoraleaes 21 ~ 39 parts of Fructus Akebiaes 20 ~ 38 parts
Herba rutae 19 ~ 37 parts of Radixs Angelicae Dahuricae 19 ~ 37 parts of Cortex Euonymi phellomaniss 18 ~ 36 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 17 ~ 35 parts
To pick up the ears 17 ~ 35 parts of Folium et Ramulus Callicarpae nudiflorae, 16 ~ 34 parts of Ptyas Korross, 16 ~ 34 parts of Cortex erythrinaes 14 ~ 32 parts
Rumalus sophorae 12 ~ 30 parts of Herba Excoecariae cochinchinensis 10 ~ 29 parts of Radix Chloranthi Serrati 10 ~ 29 parts of Spora Lygodii grass 9 ~ 27 parts.
2. a kind of medicine for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Thesii 25 ~ 37 parts of Caulis et Radix Tetrastigmatis Planicaulis 24 ~ 36 parts of Fructus Psoraleaes 24 ~ 36 parts of Fructus Akebiaes 23 ~ 35 parts
Herba rutae 22 ~ 34 parts of Radixs Angelicae Dahuricae 22 ~ 34 parts of Cortex Euonymi phellomaniss 21 ~ 33 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 20 ~ 32 parts
To pick up the ears 20 ~ 32 parts of Folium et Ramulus Callicarpae nudiflorae, 19 ~ 31 parts of Ptyas Korross, 19 ~ 31 parts of Cortex erythrinaes 17 ~ 29 parts
Rumalus sophorae 15 ~ 27 parts of Herba Excoecariae cochinchinensis 14 ~ 26 parts of Radix Chloranthi Serrati 14 ~ 26 parts of Spora Lygodii grass 12 ~ 24 parts.
3. a kind of medicine for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Thesii 28 ~ 34 parts of Caulis et Radix Tetrastigmatis Planicaulis 27 ~ 33 parts of Fructus Psoraleaes 27 ~ 33 parts of Fructus Akebiaes 26 ~ 32 parts
Herba rutae 25 ~ 31 parts of Radixs Angelicae Dahuricae 25 ~ 31 parts of Cortex Euonymi phellomaniss 24 ~ 30 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 23 ~ 29 parts
To pick up the ears 23 ~ 29 parts of Folium et Ramulus Callicarpae nudiflorae, 22 ~ 28 parts of Ptyas Korross, 22 ~ 28 parts of Cortex erythrinaes 20 ~ 26 parts
Rumalus sophorae 18 ~ 24 parts of Herba Excoecariae cochinchinensis 17 ~ 23 parts of Radix Chloranthi Serrati 17 ~ 23 parts of Spora Lygodii grass 15 ~ 21 parts.
4. a kind of medicine for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Thesii 31 parts of Caulis et Radix Tetrastigmatis Planicaulis 30 parts of Fructus Psoraleaes 30 parts of Fructus Akebiaes 29 parts
Herba rutae 28 parts of Radixs Angelicae Dahuricae 28 parts of Cortex Euonymi phellomaniss 27 parts of Caulis fici pumilae (Fructus Fici Pumilae)s 26 parts
To pick up the ears 26 parts of Folium et Ramulus Callicarpae nudiflorae, 25 parts of Ptyas Korross, 25 parts of Cortex erythrinaes 23 parts
Rumalus sophorae 21 parts of Herba Excoecariae cochinchinensis 20 parts of Radix Chloranthi Serrati 20 parts of Spora Lygodii grass 18 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the medicine of prolapse of lumbar intervertebral disc, it is characterized in that: comprise following processing step:
(1) Herba Thesii, Caulis et Radix Tetrastigmatis Planicaulis, Fructus Akebiae, Cortex Euonymi phellomanis, Ptyas Korros and Cortex erythrinae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(2) by Fructus Psoraleae, pick up the ears, Folium et Ramulus Callicarpae nudiflorae, Herba Excoecariae cochinchinensis and Spora Lygodii grass clean, put into container, add the distilled water of 8 ~ 10 times amount, soaks after 5 ~ 6 hours, boil 3 ~ 4 hours, extraction; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(3) Herba rutae and Caulis fici pumilae (Fructus Fici Pumilae) are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Radix Angelicae Dahuricae, Rumalus sophorae and Radix Chloranthi Serrati are put into container, carry out pulverization process, grind into powder, 180 object fine powders must be, for subsequent use;
(5) thick paste, juice and fine powder obtained by above-mentioned steps (1) ~ (4) are made tablet, obtain the medicine of described treatment prolapse of lumbar intervertebral disc.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113855725A (en) * | 2021-11-22 | 2021-12-31 | 杭州市西溪医院 | Application of traditional Chinese medicine Ficus pumila in preparation of medicament for treating intervertebral disc protrusion |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103316209A (en) * | 2013-06-30 | 2013-09-25 | 山西省针灸研究所 | Medicine for treating protrusion of lumbar intervertebral disc |
| CN104127554A (en) * | 2014-08-12 | 2014-11-05 | 仝义戈 | Traditional Chinese medicine for treating protrusion of lumbar intervertebral disc |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103316209A (en) * | 2013-06-30 | 2013-09-25 | 山西省针灸研究所 | Medicine for treating protrusion of lumbar intervertebral disc |
| CN104127554A (en) * | 2014-08-12 | 2014-11-05 | 仝义戈 | Traditional Chinese medicine for treating protrusion of lumbar intervertebral disc |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113855725A (en) * | 2021-11-22 | 2021-12-31 | 杭州市西溪医院 | Application of traditional Chinese medicine Ficus pumila in preparation of medicament for treating intervertebral disc protrusion |
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Application publication date: 20151223 |