CN103610822B - 一种治疗结节性脂膜炎的中药 - Google Patents
一种治疗结节性脂膜炎的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗结节性脂膜炎的中药，由以下重量配比的药材制备而成：覆盆子叶份15、弓果藤10份、布渣叶14份、宝盖草14份、白叶火草8份、饱饭花果12份、广枝仁12份、过山青22份、变叶美登木9份、勾儿茶14份、北鹤虱10份、瓜馥木16份、古钩藤15份、功劳根12份、长白假水晶兰10份、百部还魂14份、暗鳞鳞毛蕨16份。临床实验证明，本发明能够安全有效治疗结节性脂膜炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗结节性脂膜炎的中药。
背景技术
结节性脂膜炎又称特发性小叶性脂膜炎、Weber-Christian综合征或回归性发热性非化脓性脂膜炎。特征为成批反复发生的皮下结节。结节有疼痛感和显著触痛，大多数发作时伴发热，结合第二期组织病理学可以确诊。病因尚不明，可能与免疫反应异常、脂肪代谢障碍有关。好发于青壮年女性，以反复发作与成批出现的皮下结节为特征，结节消退后局部皮肤出现程度不等的凹陷和色素沉着，常伴发热、关节痛与肌痛等全身症状。
对于结节性脂膜炎目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
覆盆子叶【来源】为蔷薇科植物掌叶覆盆子的茎叶。8月，果实采收后剪下叶子，洗净，晒干或烘干。【功能主治】清热解毒，明目，敛疮。主眼脸赤烂，目赤肿痛，青盲，牙痛，臁疮，疖肿。
弓果藤【来源】为罗藦科植物弓果藤的全株。全年均可采。【功能主治】清热解毒；祛瘀止痛。。主痈肿疮毒；跌打瘀痛。
布渣叶【来源】为椴树科破布叶属植物破布树Microcos paniculata.的叶。夏秋采叶，晒干。【功能主治】清暑，消食，化痰。用于感冒，中暑，食滞，消化不良，腹泻。
宝盖草【来源】唇形科野芝麻属植物宝盖草Lamium amplexicaule L.的全草。春夏采收，洗净，鲜用或晒干。【功能主治】清热利湿，活血祛风，消肿解毒。用于黄疸型肝炎，淋巴结结核，高血压，面神经麻痹，半身不遂；外用治跌打伤痛，骨折，黄水疮。
白叶火草【来源】为菊科植物植物白千里光的根或全草。夏、秋季采收，洗净，晒干。【功能主治】散风热；定喘咳；利水湿。主感冒发热；咳喘；小便淋涩；肾炎水肿。
饱饭花果【来源】为杜鹃花科植物西南越橘的果实。7-10月采收，晒干。【功能主治】强筋骨；益气力。主筋骨酸软；四肢无力。
广枝仁【来源】为海桐花科植物光叶海桐的种子。秋季采摘果实。晒干，击破果壳，取出种仁，再晒干。【功能主治】清热利咽；止泻。主虚热心烦，口渴，咽痛；泄泻；痢疾。
过山青【来源】为亚麻科植物石海椒的嫩枝叶。春、夏季采摘嫩枝叶，鲜用或晒干。【功能主治】清热利尿。主小便不利；肾炎；黄疸型肝炎。
变叶美登木【来源】为卫矛科植物变叶美登木的地上部分，全年均可采，切段晒干。【功能主治】化瘀消肿解毒。主肿瘤。
勾儿茶【来源】为鼠李科植物牛鼻拳的根。全年可采。【功能主治】祛风湿，活血通络，止咳化痰，健脾益气。治风湿关节痛，腰痛，痛经，肺结核，瘰疬，小儿疳积，肝炎，胆道蛔虫，毒蛇咬伤，跌打损伤。
北鹤虱【来源】本品为菊科植物天名精Carpesium abrotanoides L.的干燥成熟果实。秋季果实成熟时采收，晒干，除去杂质。【功能主治】杀虫消积。用于蛔虫、蛲虫、绦虫病，虫积腹痛，小儿疳积。
瓜馥木【来源】为番荔枝科植物瓜馥木的根。【功能主治】治坐骨神经痛，关节炎。
古钩藤【来源】为萝藦科植物古钩藤的根。夏、秋季采挖，洗净，切片，晒干或鲜用。【功能主治】舒筋活络；消肿解毒；利尿。主跌打骨折；痈疮；疥癣；腰痛；腹痛；水肿。
功劳根【来源】为冬青科植物枸骨Ilex cornuta.ex Paxt.的根。全年均可采，洗净，切片，晒干。【功能主治】补肝益肾；疏风清热。主腰膝痿弱；关节疼痛；头风；赤眼；牙痛；荨麻疹。
长白假水晶兰【来源】为鹿蹄草科植物球果假水晶兰的全草。7-8月采收，晾干。【功能主治】补肺止咳。主虚咳。
百部还魂【来源】为三白草科植物裸蒴的全草或叶。【功能主治】敷跌打损伤，全株治乳疮；叶治蜈蚣咬伤。
暗鳞鳞毛蕨【来源】药材基源：为鳞鳞毛蕨科植物暗鳞鳞毛蕨的根茎。【功能主治】凉血止血；驱虫。主功能性子宫出血；蛔虫病。
发明内容
本发明旨在提供一种治疗结节性脂膜炎的中药，通过选择合适的药材及其配比，达到安全有效治愈结节性脂膜炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗结节性脂膜炎的中药，其特征在于，由以下重量配比的药材制备而成：覆盆子叶15份、弓果藤10份、布渣叶14份、宝盖草14份、白叶火草8份、饱饭花果12份、广枝仁12份、过山青22份、变叶美登木9份、勾儿茶14份、北鹤虱10份、瓜馥木16份、古钩藤15份、功劳根12份、长白假水晶兰10份、百部还魂14份、暗鳞鳞毛蕨16份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2011年11月-2012年12月间共收集79例结节性脂膜炎的门诊患者，年龄27-55岁，病程1-3年。随机分为：治疗组58例，空白组21例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程30天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程30天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常，愈后观察三个月未见复发。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(%) | 不良反应例 |
| 治疗组 | 58 | 9（15.5%） | 33（56.9%) | 16（27.6%) | 72.4% | 0 |
| 空白组 | 21 | 0 | 3（14.3%） | 18（85.7%） | 14.3% | 0 |
可见，本发明制得的药物能够安全有效治疗结节性脂膜炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：覆盆子叶15克、弓果藤10克、布渣叶14克、宝盖草14克、白叶火草8克、饱饭花果12克、广枝仁12克、过山青22克、变叶美登木9克、勾儿茶14克、北鹤虱10克、瓜馥木16克、古钩藤15克、功劳根12克、长白假水晶兰10克、百部还魂14克、暗鳞鳞毛蕨16克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗结节性脂膜炎。口服，每日分早晚两次服用。
具体实施例2
称取：覆盆子叶15克、弓果藤10克、布渣叶14克、宝盖草14克、白叶火草8克、饱饭花果12克、广枝仁12克、过山青22克、变叶美登木9克、勾儿茶14克、北鹤虱10克、瓜馥木16克、古钩藤15克、功劳根12克、长白假水晶兰10克、百部还魂14克、暗鳞鳞毛蕨16克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗结节性脂膜炎。口服，每日分早晚两次服用。
具体实施例3
称取：覆盆子叶15克、弓果藤10克、布渣叶14克、宝盖草14克、白叶火草8克、饱饭花果12克、广枝仁12克、过山青22克、变叶美登木9克、勾儿茶14克、北鹤虱10克、瓜馥木16克、古钩藤15克、功劳根12克、长白假水晶兰10克、百部还魂14克、暗鳞鳞毛蕨16克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗结节性脂膜炎。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗结节性脂膜炎的中药，其特征在于，由以下重量配比的药材制备而成：覆盆子叶15份、弓果藤10份、布渣叶14份、宝盖草14份、白叶火草8份、饱饭花果12份、广枝仁12份、过山青22份、变叶美登木9份、勾儿茶14份、北鹤虱10份、瓜馥木16份、古钩藤15份、功劳根12份、长白假水晶兰10份、百部还魂14份、暗鳞鳞毛蕨16份。
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| CN105497347A (zh) * | 2014-11-10 | 2016-04-20 | 耿新忠 | 一种治疗游走性结节性脂膜炎的中药 |
| CN104958730A (zh) * | 2015-07-21 | 2015-10-07 | 焦安贵 | 一种用于结节性脂膜炎的中药制剂及其制备方法 |
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| CN1814010A (zh) * | 2005-11-22 | 2006-08-09 | 蓝子花 | 一种勾儿茶活络镇痛药 |
| CN1814102A (zh) * | 2005-11-28 | 2006-08-09 | 蓝子花 | 一种血竭活络伤湿止痛膏 |
| CN1840125A (zh) * | 2006-01-06 | 2006-10-04 | 江西青春康源制药有限公司 | 钻山风片及其制备方法 |
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| CN1814010A (zh) * | 2005-11-22 | 2006-08-09 | 蓝子花 | 一种勾儿茶活络镇痛药 |
| CN1814102A (zh) * | 2005-11-28 | 2006-08-09 | 蓝子花 | 一种血竭活络伤湿止痛膏 |
| CN1840125A (zh) * | 2006-01-06 | 2006-10-04 | 江西青春康源制药有限公司 | 钻山风片及其制备方法 |
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