CN103599335B - 一种治疗慢性结肠炎的中药 - Google Patents

一种治疗慢性结肠炎的中药 Download PDF

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CN103599335B
CN103599335B CN201310645441.2A CN201310645441A CN103599335B CN 103599335 B CN103599335 B CN 103599335B CN 201310645441 A CN201310645441 A CN 201310645441A CN 103599335 B CN103599335 B CN 103599335B
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徐启利
孙明
解安庆
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Heze Hailai Biotechnology Co ltd
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Abstract

本发明涉及一种治疗慢性结肠炎的中药，由以下重量配比的药材制备而成：扁竹兰14份、过山枫12份、黄毛耳草12份、干地黄12份、白脂麻18份、地涩涩12份、木通七叶莲10份、安龙香科科14份、多花胡枝子15份、酱头12份、大瓦韦14份、臭矢菜12份、苍山黄堇20份、刺沙蓬14份、刺天茄叶22份、大酸浆草16份、飞来鹤16份。临床实验证明，本发明能够安全有效治疗慢性结肠炎。

Description

一种治疗慢性结肠炎的中药
技术领域
  本发明涉及一种中药，具体涉及一种治疗慢性结肠炎的中药。
背景技术
慢性结肠炎是一种慢性、反复性、多发性以结肠、乙状结肠和直肠为发病部位。指直肠结肠因各种致病原因导致肠道的炎性水肿，溃疡、出血病变。症状为左下腹疼、腹泻、里急后重、时便下沾液、便秘或泄泻交替性发生、时好时坏，缠绵不断、反复发作。慢性结肠炎是慢性结肠通常根据致病原因分为特异性，即有明显原因的结肠炎，和非特异性即致病原因不明的结肠炎。
对于慢性结肠炎目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
扁竹兰【来源】为百合科植物弯蕊开口箭的根茎，全年均可采挖。【功能主治】清热解毒；散瘀止血；消肿止痛。主感冒风热；咳嗽咽痛；扁桃体炎；淋巴结炎；跌打骨折；胃痛吐血；外伤出血。
过山枫【来源】为卫矛科植物过山枫的根。秋后采收，切片晒干。【功能主治】清热解毒；祛风除湿。主风湿痹痛；痛风；肾炎；胆囊炎；白血病。
黄毛耳草【来源】茜草科耳草属植物黄毛耳草Hedyotis chrysotricha （Palib.） Merr.的全草。全年可采。洗净鲜用或晒干。【功能主治】清热利湿，解毒消肿。用于肠炎，痢疾，急性黄疸型肝炎，小儿急性肾炎，乳糜尿，功能性子宫出血，咽喉肿痛；外用治毒蛇、蜈蚣咬伤，跌打损伤，外伤出血，疔疮肿毒。
干地黄【来源】为玄参科植物地黄的块根。10-11月采挖鲜地黄后随即用无烟火烘炕。【功能主治】滋阴清热；凉血补血。主热病烦渴；内热消渴；骨蒸劳热；温病发斑；血热所致的吐血；崩漏；尿血；便血；血虚萎黄；眩晕心悸；血少经闭。
白脂麻【来源】为胡麻科植物脂麻的白色种子。【功能主治】润燥，滑肠。治脾约便难，小儿头疮。
地涩涩【来源】为玄参科植物小婆婆纳带虫瘿的全草。6-7月采收果实中有虫瘿的全草，蒸后晒干或鲜用。【功能主治】活血散瘀；止血；解毒。主跌打损伤；月经不调；创伤出血；口疮；烫火伤。
木通七叶莲【来源】为木通科野木瓜属植物鸭脚莲，以根或全株入药。夏秋采集，洗净切片晒干备用。【功能主治】甘、温。散瘀止痛，利尿消肿。用于风湿性关节炎，跌打损伤，各种神经性疼痛，水肿，小便不利，月经不调。
安龙香科科【来源】为唇形科植物安龙香科科的全草。【功能主治】理气健胃。主消化不良；脘腹胀满。
多花胡枝子【来源】豆科多花胡枝子Lespedeza floribunda Bunge，以根入药。【功能主治】消积散瘀。主治疳积。
酱头【来源】蓼科蓼属植物酱头，以块根入药。秋季采挖，洗净切片，晒干。【功能主治】清热解毒，调经止血。用于痢疾，消化不良，胃痛，崩漏，月经不调；外用治疔疮初起，外伤出血。
大瓦韦【来源】为水龙骨科植物大瓦韦的全草。全年均可采收，洗净，晒干。【功能主治】清热解毒；利尿祛湿；止血。主暴赤火眼；翳膜遮睛；热淋；水肿；血崩；月经不调；疔疮痈毒；外伤出血。
臭矢菜【来源】白花菜科臭矢菜Cleome vircosa L.，以全草入药。【功能主治】散瘀消肿，去腐生肌。跌打肿痛，劳伤腰痛：鲜全草捣烂，酒炒外敷。
苍山黄堇【来源】为罂粟科植物苍山黄堇的全草。春、夏季采收，洗净，晒干或鲜用。【功能主治】清热解毒。主肝炎；肺炎；痈肿疮疖；毒蛇咬伤。
【来源】为藜科植物刺沙蓬的全草。夏季开花时割取，晒干。【功能主治】平肝降压。
刺天茄叶【来源】为茄科植物刺茄子的叶。夏、秋采集，晒干或鲜用。【功能主治】消炎止痛，解毒止痉。治小儿惊厥。
大酸浆草【来源】为蓼科植物戟叶酸模的根或全草。夏、秋采根或全草，洗净，晾干或鲜用。【功能主治】发汗解表；祛风除湿；止咳；止血。主感冒；头痛；风湿关节痛；咳喘；跌打损伤；崩漏。
飞来鹤【来源】为萝藤科牛皮消属植物飞来鹤（耳叶牛皮消）Cynanchum auriculatum Royle exWight，以根或全草入药。【功能主治】健胃消积，解毒消肿。用于食积腹痛，胃痛，小儿疳积，痢疾；外用治毒蛇咬伤，疔疮。
发明内容
本发明旨在提供一种治疗慢性结肠炎的中药，通过选择合适的药材及其配比，达到安全有效治愈慢性结肠炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗慢性结肠炎的中药，其特征在于，由以下重量配比的药材制备而成：扁竹兰14份、过山枫12份、黄毛耳草12份、干地黄12份、白脂麻18份、地涩涩12份、木通七叶莲10份、安龙香科科14份、多花胡枝子15份、酱头12份、大瓦韦14份、臭矢菜12份、苍山黄堇20份、刺沙蓬14份、刺天茄叶22份、大酸浆草16份、飞来鹤16份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年11月-2012年6月间共收集107例慢性结肠炎的门诊患者，年龄23-55岁，病程0.5-3年。随机分为：治疗组83例，空白组24例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程30天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程30天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常，愈后观察三个月未见复发。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1  两组疗效比较
组别 n 痊愈 好转 无效 总有效率(%) 不良反应例
治疗组 83 21（25.3%） 47（56.6%) 15（18.1%) 81.9% 0
空白组 24 0 4（16.7%） 20（83.3%） 16.7% 0
可见，本发明制得的药物能够安全有效治疗慢性结肠炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：扁竹兰14克、过山枫12克、黄毛耳草12克、干地黄12克、白脂麻18克、地涩涩12克、木通七叶莲10克、安龙香科科14克、多花胡枝子15克、酱头12克、大瓦韦14克、臭矢菜12克、苍山黄堇20克、刺沙蓬14克、刺天茄叶22克、大酸浆草16克、飞来鹤16克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗慢性结肠炎。口服，每日分早晚两次服用。
具体实施例2
称取：扁竹兰14克、过山枫12克、黄毛耳草12克、干地黄12克、白脂麻18克、地涩涩12克、木通七叶莲10克、安龙香科科14克、多花胡枝子15克、酱头12克、大瓦韦14克、臭矢菜12克、苍山黄堇20克、刺沙蓬14克、刺天茄叶22克、大酸浆草16克、飞来鹤16克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗慢性结肠炎。口服，每日分早晚两次服用。
具体实施例3
称取：扁竹兰14克、过山枫12克、黄毛耳草12克、干地黄12克、白脂麻18克、地涩涩12克、木通七叶莲10克、安龙香科科14克、多花胡枝子15克、酱头12克、大瓦韦14克、臭矢菜12克、苍山黄堇20克、刺沙蓬14克、刺天茄叶22克、大酸浆草16克、飞来鹤16克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗慢性结肠炎。口服，每日分早晚两次服用。

Claims (1)

1.一种治疗慢性结肠炎的中药，其特征在于，由以下重量配比的药材制备而成：扁竹兰14份、过山枫12份、黄毛耳草12份、干地黄12份、白脂麻18份、地涩涩12份、木通七叶莲10份、安龙香科科14份、多花胡枝子15份、酱头12份、大瓦韦14份、臭矢菜12份、苍山黄堇20份、刺沙蓬14份、刺天茄叶22份、大酸浆草16份、飞来鹤16份。
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CN103301338A (zh) * 2013-06-14 2013-09-18 全清清 一种治疗血友病的中药制剂及制备方法

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Patentee before: Juancheng Shiji Town Health Center

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Denomination of invention: Traditional Chinese medicine for treating chronic colitis

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Denomination of invention: A Traditional Chinese Medicine for the Treatment of Chronic Colitis

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