CN103623083B - 一种治疗膈膜炎的中药 - Google Patents
一种治疗膈膜炎的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗膈膜炎的中药，它是由以下重量配比的原料药材制备而成：鸡血藤6份、土鳖虫6份、筋骨草4份、风湿木3份、欧当归4份、檀香3份、铁苋3份、芙蓉花5份、番泻叶1份、枇杷叶3份、瓜蒌2份、木通1份、大黄4份、豆根2份、石膏2份、万年柏3份、甘草5份。临床实验证明，本发明能够安全有效治疗膈膜炎。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗膈膜炎的中药。
背景技术
膈膜炎是胸腔和腹腔之间的膜状肌肉发炎。发病原因为细菌性炎症或外力外伤引起。目前膈膜炎治疗主要是应用手术和抗生素，疗效低，且副作用大。因此研究开发一种安全有效治疗膈膜炎的中药非常有临床实用价值。
本发明中药所涉及药材的研究现状如下：
鸡血藤：本品为豆科植物密花豆（大血藤、血风藤、三叶鸡血藤、九层风）Spatholobus suberectus Dunn 的干燥藤茎。【性味】苦、甘，温。【归经】归肝、肾经。【功能主治】补血，活血，通络。用于月经不调，血虚萎黄，麻木瘫痪，风湿痹痛。【用法用量】9～15g。
土鳖虫：本品为鳖蠊科昆虫地鳖Eupolyphaga sinensis Walker 或冀地鳖Steleophaga plancyi（Boleny）的雌虫干燥体。【性味】咸，寒；有小毒。【归经】归肝经。【功能主治】破瘀血，续筋骨。用于筋骨折伤，瘀血经闭，症瘕痞块。【用法用量】 3～9g。
筋骨草：唇形科筋骨草属植物筋骨草Ajuga decumbens Thunb.的全草。【性味】味苦；性寒。【功能主治】清热解毒；凉血消肿。主咽喉肿痛；肺热咯血；跌打肿痛。【用法用量】内服：煎汤，15-30g。
风湿木：本品为夹竹桃科风湿木Rauvolfia latifrons Tsiang，以根、茎入药。【功能主治】祛风活血。主治风湿痛；外用可接骨。
欧当归：本品为伞形科杆物欧当归的根。【性味】味辛；微甘；性微温。【功能主治】活血调经；利尿。主经闭；痛经；头晕；头痛；肢麻；水肿。【用法用量】6-15g。
檀香：本品为檀香科檀香属植物檀香Santalum album L.树干的心材。【性味】辛，温。【归经】归脾、胃、心、肺经。【功能主治】行气温中，开胃止痛。用于寒凝气滞，胸痛，腹痛，胃痛食少；冠心病，心绞痛。【用法用量】 2～5g。
铁苋：本品为大戟科植物铁苋菜的全草。【性味】苦；涩；凉。【归经】心；肺；大肠；小肠经。【功能主治】清热利湿；凉血解毒；消积。主痢疾；泄泻；吐血；衄血；尿血；崩漏；小儿疳积；痈疖疮疡；皮肤湿疹。【用法用量10-15g。
芙蓉花：为锦葵科植物木芙蓉的花。【性味】辛；微苦；凉。【归经】肺；心；肝经。【功能主治】清热解毒；凉血止血；消肿排脓。主肺热咳嗽；吐血；目赤肿痛；崩漏；白带；腹泻；腹痛；痈肿；疮疖；毒蛇咬伤；水火烫伤；跌打损伤。【用法用量】9-15g。
番泻叶:本品为豆科植物狭叶番泻 Cassia angustifolia Vahl或尖叶番泻 Cassia acutifolia Delile 的干燥小叶。【性味】甘、苦，寒。【归经】归大肠经。【功能主治】泻热行滞，通便，利水。用于热结积滞，便秘腹痛，水肿胀满。【用法用量】 2～6g.
枇杷叶：本品为蔷薇科植物枇杷Eriobotrya japonica （Thunb.）Lindl.的干燥叶。【性味】苦，微寒。【归经】归肺、胃经。【功能主治】清肺止咳，降逆止呕。用于肺热咳嗽，气逆喘急，胃热呕逆，烦热口渴。【用法用量】 6～9g。
瓜蒌：本品为葫芦科植物栝楼Trichosanthes kirilowii Maxim. 或双边栝楼Trichosan-thes rosthornii Harms 的干燥成熟果实。【性味】甘、微苦、寒。【归经】归肺、胃、大肠经。【功能主治】清热涤痰，宽胸散结，润燥滑肠。用于肺热咳嗽，痰浊黄稠，胸痹心痛，结胸痞满，乳痈，肺痈，肠痈肿痛，大便秘结。【用法用量】 9～15g。
木通：本品为木通科植物木通、三叶木通或白木通的滕茎。【性味】苦；性寒。【归经】心；脾；肾；小肠；膀胱经。【功能主治】清热利尿；活血通脉。主小便赤赤；淋浊；水肿；胸中烦热；喉喉疼痛；口舌生疮；风湿痹痛；乳汁不通；经闭；痛经。【用法用量】3-6g。
大黄：本品为蓼科植物掌叶大黄Rheum palmatum L。、 唐古特大黄Rheum tanguticum Maxim。 ex Balf。或药用大黄Rheum officinale Baill。的干燥根及根茎。【性味】苦，寒。【归经】归脾、胃、大肠、肝、心包经。【功能主治】泻热通肠，凉血解毒，逐瘀通经。用于实热便秘，积滞腹痛，泻痢不爽，湿热黄疸，血热吐衄，目赤，咽肿，肠痈腹痛，痈肿疔疮，瘀血经闭，跌打损伤，外治水火烫伤；上消化道出血。酒大黄善清上焦血分热毒。用于目赤咽肿，齿龈肿痛。熟大黄泻下力缓，泻火解毒。用于火毒疮疡。大黄炭凉血化瘀止血。用于血热有瘀出血症。【用法用量】 3～30g。
豆根：本品为豆科木蓝属植物花木蓝Indigofera Kirilowii Maxim. ex Palibin，以根入药。【性味】苦，寒。【功能主治】清热解毒，消肿止痛，通便。用于咽喉肿痛，肺热咳嗽，黄疸，热结便秘；外用治痔疮肿痛，蛇虫咬伤。
万年柏：为蕨类铁角蕨科铁角蕨属植物虎尾铁角蕨，以全草入药。【性味】苦、甘，凉。【功能主治】清热解毒，平肝镇惊，止痛。用于肝炎，小儿疳积，牙痛，毒蛇咬伤。【用法用量】2～5g。
甘草：本品为豆科植物甘草 Glycyrrhiza uralensis Fisch.、胀果甘草 Glycyrrhiza inflata Bat. 或光果甘草 Glycyrrhiza glabra L. 的干燥根。【性味】甘，平。【归经】归心、肺、脾、胃经 。【功能主治】补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。【用法用量】 1.5～9g。
发明内容
本发明旨在提供一种治疗膈膜炎的中药，通过选择合适的药材及其配比，达到安全有效治愈膈膜炎的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗膈膜炎的中药，其特征在于，它是由以下重量配比的原料药材制备而成：鸡血藤6份、土鳖虫6份、筋骨草4份、风湿木3份、欧当归4份、檀香3份、铁苋3份、芙蓉花5份、番泻叶1份、枇杷叶3份、瓜蒌2份、 木通1份、大黄4份、豆根2份、万年柏3份、甘草5份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年1月-2013年4月间共收集50例膈膜炎患者，年龄18-54岁，病程1-3个月。随机分为：治疗组25例，对照组25例。两组性别、年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗方法
对照组服用头孢克定，按说明书用，疗程10天。
治疗组口服本发明按照具体实施例1制得的胶囊，每日2次。疗程10天。
2.2观察项目：实验前后，对疼痛，肿块、结节大小、体温及血液生化指标化验记录。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常，半年内未见复发。好转：临床症状减轻，实验室检查改善或正常。无效：临床症状、实验室检查无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 不良反应例 | 总有效率(%) |
| 治疗组 | 25 | 18 | 3 | 3 | 1（4%） | 88% |
| 对照组 | 25 | 3 | 6 | 16 | 22（88%） | 36% |
可见，本发明制得的药物能够安全有效治疗膈膜炎。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取鸡血藤6g、土鳖虫6g、筋骨草4g、风湿木3g、欧当归4g、檀香3g、铁苋3g、芙蓉花5g、番泻叶1g、枇杷叶3g、瓜蒌2g、 木通1g、大黄4g、豆根2g、万年柏3g、甘草5g；加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人一天用量的胶囊剂。
用于治疗膈膜炎。口服，每日分早晚两次服用。
具体实施例2
称取鸡血藤6g、土鳖虫6g、筋骨草4g、风湿木3g、欧当归4g、檀香3g、铁苋3g、芙蓉花5g、番泻叶1g、枇杷叶3g、瓜蒌2g、 木通1g、大黄4g、豆根2g、万年柏3g、甘草5g；加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常成人一天用量的散剂。
用于治疗膈膜炎。口服，每日一次。
具体实施例3
称取鸡血藤6g、土鳖虫6g、筋骨草4g、风湿木3g、欧当归4g、檀香3g、铁苋3g、芙蓉花5g、番泻叶1g、枇杷叶3g、瓜蒌2g、 木通1g、大黄4g、豆根2g、万年柏3g、甘草5g；加6倍量水，煎煮3次，每次煎煮1小时，合并煎煮液，浓缩，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人一天用量的颗粒剂。
用于治疗膈膜炎。口服，每日分早中晚三次服用。
Claims (1)
1.一种治疗膈膜炎的中药，其特征在于，它是由以下重量配比的原料药材制备而成：鸡血藤6份、土鳖虫6份、筋骨草4份、风湿木3份、欧当归4份、檀香3份、铁苋3份、芙蓉花5份、番泻叶1份、枇杷叶3份、瓜蒌2份、 木通1份、大黄4份、豆根2份、万年柏3份、甘草5份。
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| CN101732467A (zh) * | 2008-11-10 | 2010-06-16 | 北京以岭药业有限公司 | 一种中药组合物在制备治疗化脓性胸膜炎药物中的应用 |
| CN101934041A (zh) * | 2010-09-10 | 2011-01-05 | 重庆市南川区金佛山中药材品种培育研究所 | 治疗胸膜炎的中草药 |
| CN103285346A (zh) * | 2013-05-06 | 2013-09-11 | 安徽省颍上县中医院 | 一种治疗胸膜炎的中药组合物及其制备方法 |
| CN103432246A (zh) * | 2013-07-31 | 2013-12-11 | 刘海珍 | 一种治疗急性渗出性胸膜炎的中药组合物 |
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| CN101732467A (zh) * | 2008-11-10 | 2010-06-16 | 北京以岭药业有限公司 | 一种中药组合物在制备治疗化脓性胸膜炎药物中的应用 |
| CN101934041A (zh) * | 2010-09-10 | 2011-01-05 | 重庆市南川区金佛山中药材品种培育研究所 | 治疗胸膜炎的中草药 |
| CN103285346A (zh) * | 2013-05-06 | 2013-09-11 | 安徽省颍上县中医院 | 一种治疗胸膜炎的中药组合物及其制备方法 |
| CN103432246A (zh) * | 2013-07-31 | 2013-12-11 | 刘海珍 | 一种治疗急性渗出性胸膜炎的中药组合物 |
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