CN103599388A - Traditional Chinese medicine decoction for treating dysfunctional uterine bleeding - Google Patents

Abstract

The invention relates to the field of medicine formulation, and in particular to a traditional Chinese decoction for treating dysfunctional uterine bleeding. The traditional Chinese decoction is characterized by comprising the following raw materials by weight percent: 10-13% of scutellaria baicalensis, 9-12% of dendrobium nobile, 8-11% of coking gardenia, 9-11% of fructus ligustri lucidi, 8-11% of charred cyrtomium fortune, 5-7% of astragalus membranaceus, 4-6% of motherwort fruit, 5-7% of rubus idaeus, 6-9% of ligusticum wallichii, 5-7% of radix aconiti lateralis preparata, 4-7% of red flower, 3-5% of semen cuscutae and 2-5% of rubia cordifolia. The 13 traditional Chinese medicines are soaked by water and decocted to obtain filtrate after removing slag. The decoction treating dysfunctional uterine bleeding is high in curative effect, free from toxic and side effect and suitable for ovulatory uterine bleeding and anovulatory uterine bleeding.

Description

The Chinese medicine decoction for the treatment of dysfunctional uterine bleeding

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine decoction for the treatment of dysfunctional uterine bleeding.

Background technology

As everyone knows, dysfunctional uterine bleeding is called for short " anovulatory dysfunctional uterine hemorrhage ", is equivalent to " metrorrhagia " category of Chinese medicine.Refer to without systemic disease and genitals's organic disease, but take due to what neuroendocrine system dysfunction caused the metrorrhagia that menoxenia is feature.Anovulatory dysfunctional uterine hemorrhage divides anovulation type and has ovulation type.There is the multiple Women of Childbearing Age of being born in of ovulation type anovulatory dysfunctional uterine hemorrhage, the multiple climacteric women of being born in of anovulatory functional bleeding.The metrorrhagia that menoxenia is feature is mainly take in its clinical manifestation.There is ovulation type anovulatory dysfunctional uterine hemorrhage main manifestations: menstrual cycle shortens, menorrhagia, menostaxis; Anovulatory functional bleeding main manifestations: unexpected vaginal hemorrhage, amount is many or not to the utmost dripping, vexed hectic fever, feverish sensation in the palms and soles, spiritlessness and weakness etc.Clinical treatment often adopts gonadal hormone hemostasis and adjusts menstrual cycle.A large amount of prolonged application gonadotherapies are stopped blooding, and not only cost is large, and malignant tumor easily occurs, and operative treatment, as endometrium excision, hysterectomy etc. have not only brought great financial burden to patient, has brought great actual bodily harm to patient simultaneously simultaneously.

Summary of the invention

Object of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, a kind of Chinese medicine decoction for the treatment of dysfunctional uterine bleeding is provided, cost is low, instant effect, treatment dysfunctional uterine bleeding curative effect is high, has no side effect, there is QI and blood regulating, control and collapse should ascending astringent or styptic treatment for spontaneous sweatingly, control the function that leakage should nourish blood and regulate the flow of vital energy, be applicable to ovulation and various metrorrhagia of anovulation phase.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine decoction for the treatment of dysfunctional uterine bleeding, it is characterized in that raw material composition is by weight percentage: Radix Scutellariae 10～13%, Herba Dendrobii 9～12%, Fructus Gardeniae Preparatus 8～11%, Fructus Ligustri Lucidi 9～11%, GUANZHONGTAN 8～youngster %, the Radix Astragali 5～7%, Fructus Leonuri 4～6%, Fructus Rubi 5～7%, Rhizoma Chuanxiong 6～9%, Radix Aconiti Lateralis Preparata 5～7%, Flos Carthami 4～7%, Semen Cuscutae 3～5%, Radix Rubiae 2～5%, above-mentioned 13 taste Chinese medicines are soaked in water, the filtrate of removing slag to obtain after decocting.

Beneficial effect of the present invention is, cost is low, instant effect, and treatment dysfunctional uterine bleeding curative effect is high, has no side effect, and has QI and blood regulating, controls to collapse should ascending astringent or styptic treatment for spontaneous sweatingly, controls the function that leakage should nourish blood and regulate the flow of vital energy, and has been applicable to ovulation and various metrorrhagia of anovulation phase.

The specific embodiment

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1:

First by following component (% by weight), get clean Radix Scutellariae 10.48, Herba Dendrobii 10.48, Fructus Gardeniae Preparatus 10.48, Fructus Ligustri Lucidi 10.48, GUANZHONGTAN 10.48, the Radix Astragali 6.3, Fructus Leonuri 6.3, Fructus Rubi 6.3, Rhizoma Chuanxiong 8.4, Radix Aconiti Lateralis Preparata 6.3, Flos Carthami 6.3, Semen Cuscutae 4.2, Radix Rubiae 3.5.Often take medicine 227 grams, under greenhouse, 13 taste Chinese herbal medicine are added water to 800～1000ml, soak 3～5 hours, then boil with high heat, slow fire decocts to about 80～100 minutes, and filtrate 200ml removes slag to obtain, medicinal residues add water 300～400ml again, decoct about 30 minutes, and filtrate 100ml removes slag to obtain, be total to obtain 300ml medicinal liquid, the Chinese medicine decoction that makes treatment dysfunctional uterine bleeding, packs in aseptic vial, and envelope bottle cap is standby, 1 dose minute every day 2 times is oral, each (medicine) being taken before meal 150ml.

Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, antiabortive, cooling blood for hemostasis in of the present invention group.Blood pressure lowering, calmness, anti-microbial effect, to blood fat and blood glucose effect.Diuresis, relieving asthma etc.; Herba Dendrobii reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Stomach promotes the production of body fluid, nourishing YIN and clearing away heat.For cloudy impairment of body fluid, lose, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision; Fructus Gardeniae Preparatus is bitter, cold.GUIXIN, lung, tri-jiao channel.Cooling blood for hemostasis.For heat in blood, tell nosebleed, hematuria metrorrhagia; Fructus Ligustri Lucidi is for the poor vision of the hepatic and renal YIN deficiency, visual deterioration, early whitening of beard and hair, soreness of waist tinnitus and fever due to yin deficiency etc.; GUANZHONGTAN is controlled dysfunctional uterine hemorrhage, to digestive tract hemorrhage, hematuria, a small amount of, spits blood also effective in cure; Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool; Fructus Leonuri promoting blood flow to regulate menstruation, wind and heat dispersing.Control menoxenia, metrorrhagia leukorrhagia, postnatal blood stasis is had a pain; Liver-heat headache, conjunctival congestion and swelling pain, or raw nebula film; Fructus Rubi the liver and the kidney tonifying, controlling nocturnal emission with astringent drugs reducing urination, improving eyesight cures mainly, impotence and premature ejaculation, emission and spermatorrhea, cold womb is infertile, and leukorrhagia is rare clearly, frequent micturition incontinence of urine, blurred vision is dark, early whitening of beard and hair; Rhizoma Chuanxiong activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia; Radix Aconiti Lateralis Preparata is pungent, sweet, hot greatly, poisonous.GUIXIN, kidney, spleen channel.Recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispersing cold for relieving pain.For YANG-depletion collapse, cold extremities faint pulse, deficiency of heart-YANG, obstruction of qi in the chest and cardialgia; Flos Carthami is warm in nature, acrid in the mouth, the latus rectum of invigorating blood circulation, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.Applicable various varicosis, peripheral neuritis, blood circulation is bad, lower limb numbness or the congestion such as livid purple; Semen Cuscutae nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen, suffer from a deficiency of the kidney and rush down; Radix Rubiae nature and flavor are bitter, cold.Return Liver Channel.There is cooling blood for hemostasis, blood stasis dispelling, the effect of stimulating the menstrual flow.Cure mainly heat in blood and tell nosebleed, metrostaxis, blood stasis amenorrhea, traumatic injury, rheumatic arthralgia.The ingenious prescription of 13 taste Chinese medicine, the mutual coordinative role of medicine, to improve principal agent effect, offsets adverse drug effect, the specially good effect of playing altogether dysfunctional uterine bleeding.

The embodiment that each raw material of the present invention also can the listed ratio of according to the form below (percentage by weight) mixes realizes.Its processing technique is identical with embodiment 1.

The clinical trial of carrying out below in conjunction with my institute is done further, is described in detail the present invention:

1, case selection: this organizes 60 examples, in age 26-53 year, all cases is all the dysfunctional uterine bleeding that degree is different.

2, diagnostic criteria: formulate diagnostic criteria with reference to the diagnosis basis about metrorrhagia in the < < of State Administration of Traditional Chinese Medicine traditional Chinese medical science disease Standardization of diagnosis and curative effect > > [1].(1) the confusion of the menstrual cycle, does not have rule completely, and menstrual phase is different in size, and even the several months is continuous; (2) menorrhagia, or sudden and violent lower as notes, or persistent vaginal bloody discharge, or both alternately occur.During serious symptom, circulatory failure in a moment; A small amount of hemorrhage dripping shape that is, even drop shape is hemorrhage.(3), from whole medical history, with frequent irregular bleeding, it is main that blood volume mostly is.Therefore anemia is also common sympton, and course of disease elder can present spiritlessness and weakness, and pale complexion is nervous.(4) diagnosis is assisted in diagnostic curettage, hormone determination or other auxiliary examination.

All cases is all by above standard screening, and clinical main manifestations is: menstrual cycle, disorder of menstrual cycle, reach above standard.Few when many when hemorrhage, off and on, or suddenly bleed profusely and continue with dripping urine endlessly, severe one with anemia and other symptom in various degree.

Exclusion standard (1) patient age is below 14 years old or more than 55 years old; (2) gestation or women breast-feeding their children; (3) allergic constitution or those who are allergic to this drug; (4) be associated with cardiovascular, liver, the serious primary disease of kidney and psychotic.(5) through the relevant inspection of medical science, with hemorrhage relevant systemic disease and reproductive system organic disease patient.

3, Therapeutic Method: often take medicine 227 grams, under greenhouse, 13 taste Chinese herbal medicine are added water to 800～1000ml, soak 3～5 hours, then boil with high heat, slow fire decocts to about 80～100 minutes, the filtrate 200ml that removes slag to obtain, medicinal residues add water 300～400ml again, decoct about 30 minutes, filtrate 100ml removes slag to obtain, be total to obtain 300ml medicinal liquid, make the Chinese medicine decoction for the treatment of dysfunctional uterine bleeding, pack in aseptic vial, envelope bottle cap is standby, 1 dose minute every day 2 times is oral, and each (medicine) being taken before meal 150ml, treats three months altogether.

4, curative effect judging standard: the criterion of therapeutical effect for the treatment of dysfunctional uterine bleeding guideline of clinical investigations > > [2] with reference to < < new Chinese medicine is in conjunction with clinical treatment practical situation, formulation efficacy assessment standard is as follows: recovery from illness: after Bleeding control, continuous 3 menstrual cycle, menstrual period, blood volume are all normal, and subjective symptoms disappears; Or the only rear menopause person of climacteric women blood; Effective: after Bleeding control, menstrual cycle blood volume normal, menstrual period are long (more than 7d, 10d is following) still, and subjective symptoms disappears; Effective: menstrual cycle, menstrual period, partial symptoms are obviously improved, oligemia; Invalid: above every all without improver.

5, therapeutic effect: use compound recipe garden burnet and hairyvein agrimony soup of the present invention to treat altogether 60 examples, result recovery from illness 43, effective 9, effective 5 examples, invalid 3 examples, effective percentage is 95%, inefficiency is 5%.

Claims (1)

1. a Chinese medicine decoction for the treatment of dysfunctional uterine bleeding, it is characterized in that: raw material composition is by weight percentage, Radix Scutellariae 10～13%, Herba Dendrobii 9～12%, Fructus Gardeniae Preparatus 8～11%, Fructus Ligustri Lucidi 9～11%, GUANZHONGTAN 8～11%, the Radix Astragali 5～7%, Fructus Leonuri 4～6%, Fructus Rubi 5～7%, Rhizoma Chuanxiong 6～9%, Radix Aconiti Lateralis Preparata 5～7%, Flos Carthami 4～7%, Semen Cuscutae 3～5%, Radix Rubiae 2～5%, above-mentioned 13 taste Chinese medicines are soaked in water, the filtrate of removing slag to obtain after decocting.