CN103599205B - Traditional Chinese medicine liquid of control wound infection and preparation method thereof - Google Patents
Traditional Chinese medicine liquid of control wound infection and preparation method thereof Download PDFInfo
- Publication number
- CN103599205B CN103599205B CN201310600043.9A CN201310600043A CN103599205B CN 103599205 B CN103599205 B CN 103599205B CN 201310600043 A CN201310600043 A CN 201310600043A CN 103599205 B CN103599205 B CN 103599205B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- preparation
- herba
- wound infection
- rhizoma coptidis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of traditional Chinese medicine liquid of preventing and treating wound infection and preparation method thereof, it is made up of the raw material of following parts by weight: Rhizoma Coptidis 10-15 part, Herba Duchesneae Indicae 10-15 part, Fructus Forsythiae 10-20 part, Herba Portulacae 10-20 part, preparation method is: Rhizoma Coptidis, Herba Duchesneae Indicae, YINQIAO and Herba Portulacae are pulverized, boil 20-30 minute with a medicine gross weight 3-5 times clear water, filter, filtering residue adds 1-2 clear water doubly, then boils 10-15 minute, merges twice filtrate, bottling, Aseptic sterilisation.Using method: be directly applied in affected part.The present invention, has no side effect for raw material with pure Chinese medicine, has no drug resistance, and preparation process is simple, with low cost, time saving and energy saving, easy to use.
Description
Technical field
The present invention relates to formula of a kind of traditional Chinese medicine liquid, the particularly traditional Chinese medicine liquid of preventing and treating wound infection and preparation method thereof.
Background technology
Wound infection after to be pathogenic microorganism invade body by wound, grows in vivo, breeds, and causes the normal function of body, metabolism, organizational structure be damaged, cause the pathological reaction of tissue-damaging pathological changes.After body is subject to pathogen invasion, various defense function can be mobilized to eliminate pathogen and toxic product thereof, to recover the relative stability of body.Whether pathogen can cause infection after invading body, depends primarily on the virulence of pathogen and the resistance of body.
The symptom of wound infection: 1, the symptom of wound pain, tenderness, local swelling, rubescent heating often appears in some common shallow table wound infections.2, often there is purulent secretion in some darker wounds, and patient also there will be gully pain simultaneously, red and swollen symptom, and the symptom of fever appears in some patients.Do not control in time if 3 patient wound infect, infecting and continue to increase the weight of, there is ulcer or even gangrene in wound location, and the systemic toxicity symptom of high heat, stupor and so on even appears in serious patient.
The method of current treatment wound infection uses antibiotics Western medicine mostly, and toxic and side effects is large, has drug resistance, unsuitable life-time service.
Through retrieval, the open source literature that we have found about the traditional Chinese medicine liquid of control wound infection is as follows:
1. Chinese patent, Application Number (patent): CN200410102766.7 title: the Chinese medicine composition for the treatment of skin infection and wound infection; Open (bulletin) number: CN1651012 applies for (patent right) people: Meng Qingjuan; Address: 100085 No. 102, No. 1st, Qing Shang garden, Haidian District, Beijing City building 2 unit; Summary: the invention provides a kind of Chinese medicine composition for the treatment of skin infection and wound infection, the crude drug primarily of following weight portion is made: soybean oil 1000-1400 part, bark of willow 250-300 part, Olibanum 4-6 part, Myrrha 4-6 part, Sanguis Draxonis 3-5 part and Zaocys 170-230 part.Medicine of the present invention is used for the treatment of wound infection, can play reducing swelling and alleviating pain, by silt evacuation of pus effect, impels wound granulation tissue growth, accelerates its healing.
2. Chinese patent, Application Number (patent): CN200910143182.7 title: a kind of Chinese medicine for external application medicine and manufacture method for the treatment of surgical wound infection; Open (bulletin) number: CN101543565 applies for (patent right) people: Bu Jiwu; Address: 161041 unit 301 Room, two, national treasure community, Tiexi, Fulaerji District, Qiqihar City, Heilongjiang Province 3; Summary: a kind of Chinese medicine for external application medicine and manufacture method for the treatment of surgical wound infection.Be raw material by stir-baked SQUAMA MANITIS, Sanguis Draxonis, Radix Notoginseng, Halloysitum Rubrum, Olibanum, Myrrha, Vermilion, catechu, Margarita powder, Os Draconis (calcined), Calomelas, Borneolum Syntheticum, Semen Sesami wet goods Chinese crude drug, mild in medicine property and, have no side effect, medication is few, and change dressings simple, effect is good, poison is carried in the corruption of linking closely of prescription, blood circulation promoting and blood stasis dispelling, promoting tissue regeneration and wound healing, invigorating qi and benefiting blood, take stopgap measures and effect a permanent cure, curative effect is remarkable fast, and the cycle of curing is short, and cure rate is high; Manufacture method meets Traditional Chinese Medicine technique, and equipment is simple, with short production cycle, energy-saving and water-saving, product cost is low, pollution-free, relieves the untoward reaction brought because frequent replacing external application medicine repeatedly removes downright bad infected tissue with operation in surgery conventional therapy wound infection.
3. Chinese patent, application number: CN201210435957.X title: the medicine for the treatment of wound infection, open (bulletin) number: CN102920776A, application (patent right) people: Su Jiachen, invention (design) people: Su Jiachen; Address: 11 groups, Si Liying village of Xiangcheng County Shi Lipu township of Henan Province summary: the invention discloses a kind of medicine for the treatment of wound infection, belongs to medical product technical field.Medicine of the present invention is made up of Fructus Crotonis, Semen Ricini, bad Semen Juglandis and Adeps sus domestica.Make paste to pound into cordierite device on bluestone board.The old oil that Adeps sus domestica adopts twelfth month for subsequent use as far as possible.Four taste drug matchings, play unique curative effect altogether.Medicine of the present invention adopts pure natural plant, animal to be raw material, the pharmaceutical composition be prepared from by certain technique, and infecting skin wound has unique curative effect, and not only curative effect is high, and more after do not recur.The raw materials used wide material sources of medicine of the present invention, with low cost, preparation method is simple, three-waste free discharge in production.
4. Chinese patent, application number: CN200410021772.X title: a kind of inflammation-resisting pain-stopping external use Chinese medicine for the treatment of wound infection, open (bulletin) number: CN1650913, application (patent right) people: Yang Derong, invention (design) people: Yang Derong; Address: honest and sincere township, Pujiang County, Chengdu, Sichuan Province two groups, Ma Hu village summary: the invention discloses a kind of inflammation-resisting pain-stopping external use Chinese medicine for the treatment of wound infection, include following component by weight percentage: Cortex Moutan 30-35%, Radix Isatidis 18-23%, Rhizoma Cyperi 30-35%, Radix Polygoni Multiflori 1-3%, Caulis Polygoni Multiflori 2-5%, Caulis Polygoni Multiflori leaf 8-13%; Advantage of the present invention is: the significant curative effect that treatment skin wound, wound infection, wound ulcer and sore are had to antiinflammatory, ease pain, wound Kuai Su More is closed.
5. Chinese patent, application number: CN201110059294.1 title: a kind of Chinese medicine for outer use for the treatment of wound and preparation method thereof, open (bulletin) number: CN102139029A, application (patent right) people: Shandong Shenghong Medicine Science & Technology Co., Ltd., invention (design) people: Liu Xishan, address: No. 3359, east wind East Street, high and new technology industrial development zone, Weifang City of Shandong Province summary: the invention discloses a kind of Chinese medicine for outer use for the treatment of wound and preparation method thereof, crude drug primarily of following weight portion: Radix Notoginseng 25 ~ 35 parts, Galla Chinensis 35 ~ 45 parts, Resina Draconis 25 ~ 35 parts, Myrrha 3 ~ 10 parts, Herba Cirsii 3 ~ 10 parts, Lignum Dalbergiae Odoriferae 3 ~ 10 parts is pulverized and mixed, the heating and refluxing extraction that adds water respectively twice, medicinal liquid is merged and concentrates, ethanol is added in concentrated solution, Aspirate supernatant after placing, after separation of ethanol is reclaimed, obtain Chinese medicine stock solution, described Chinese medicine stock solution being added purified water, to be adjusted to middle concentration be 50 ~ 60wt%, circulation stirring, fill after fine straining, seal the wound Chinese medicine preparation that obtains medical treatment.The present invention adopts rational formula and proportioning, and the Chinese medicine preparation of preparation is used for the treatment of wound, and not only haemostatic effect is good, and incrustation is fast, and crust difficult drop-off, decreases the chance of wound infection, improves curative effect.
Summary of the invention
The object of the invention is to provide a kind of to market and be different from Chinese medicine Pharmaceutical of the control wound infection of existing formula and preparation method thereof, can prevent and treat wound infection, pure Chinese medicine formula, has no side effect, and curative effect is high, not easily recurs more,
To achieve these goals, technical scheme of the present invention is:
The traditional Chinese medicine liquid of control wound infection, is characterized in that: it is made up of the raw material comprising following portions by weight:
Rhizoma Coptidis 10-15 part;
Herba Duchesneae Indicae 10-15 part;
Fructus Forsythiae 10-20 part;
Herba Portulacae 10-20 part;
The preparation method of the traditional Chinese medicine liquid of the above control wound infection is: Rhizoma Coptidis, Herba Duchesneae Indicae, YINQIAO and Herba Portulacae are pulverized, with medicine gross weight 3-5 times of clear water water boil 20-30 minute, filter, filtering residue adds 1-2 clear water doubly, boil 10-15 minute again, merge twice filtrate, bottling, Aseptic sterilisation.Using method: be directly applied in affected part.
Above-described Rhizoma Coptidis [Classification system] Coptischinensis, another name: Rhizoma Coptidis, Jiang Lian, Rhizoma Coptidis, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice, RHIZOMA COPTIDIS from Sichuan of China.Rhizoma Coptidis is a kind of conventional Chinese medicine, just the most on the books in Shennong's Herbal, because its rhizome is beaded and yellow skin, so be referred to as " Rhizoma Coptidis ".There is heat clearing and damp drying, effect of eliminating fire and detoxication.Cure mainly the burning hot second of calentura, high heat is irritated, unconsciousness and delirium; Hyperactivity of heart-fire, chest and diaphragm heat is vexed, vexed insomnia, aphtha of the mouth and tongue; Bleeding due to blood-heat, spits blood, clot blood; Liver-fire conjunctival congestion and swelling pain; Gastropyretic vomiting, quenches one's thirst, gingival swelling and pain; The intestines and stomach is damp and hot, and gastral cavity abdomen feeling of fullness, has loose bowels, dysentery; Pathopyretic ulcer, eczema, scalds.Rhizoma Coptidis also has good antibacterial action, can resist staphylococcus aureus, Hemolytic streptococcus, streptococcus pneumoniae, meningococcus, dysentery bacterium, anthrax bacillus etc.
Above-described Herba Duchesneae Indicae [Classification system] Emiliasonchifolia (L.) DC, has another name called YEXIAHONG, Radix seu Folium Alchorneae trewioidis, red autumnal leaves grass, Semen astragali sinici, Herba Emiliae, red back of the body fruit, azurite is red etc.Property is put down, and bitter in the mouth is micro-pungent, removing pathogenic heat from blood and toxic substance from the body, promoting blood circulation to remove blood stasis, inducing diuresis to remove edema.Function cures mainly: heat clearing away, diuretic, removing heat from blood, removing toxic substances.Control dysentery, diarrhoea, have blood in stool, edema, acute appendicitis, engages ear, order also, throat moth, furuncle, toxic swelling.
Above-described Fructus Forsythiae [Classification system] Forsythiasuspensa, has another name called Hemerocallis citrina Baroni bar, Fructus Forsythiae, green grass or young crops sticks up, falls to sticking up, Huang Qidan.Fructus Forsythiae is the Chinese medicine of heat-clearing and toxic substances removing, cures mainly calentura from the beginning of, anemopyretic cold, heating, vexed, laryngopharynx swelling and pain, acute nephritis etc.Attribute: bitter, is slightly cold.Return lung, the heart, gallbladder meridian.Fructus Forsythiae has broad-spectrum antibacterial action, has very strong inhibitory action to staphylococcus aureus, Hayes dysentery bacterium, has certain inhibitory action to other pathogenic bacterium, influenza virus, fungus.There is antiinflammatory action.Oleanolic acid contained by this product has heart tonifying, diuresis and hypotensive activity, and Citrin can reduce vascular permeability and fragility, prevents haemolysis.Decoct has the town effect of telling, anti-liver injury effect.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens.Cure mainly carbuncle sore tumefacting virus, sucutaneous nodule scrofula, affection due to external wind and heat, epidemic febrile disease is from the beginning of, puckery pain of pyretic stranguria etc.
Above-described Herba Portulacae [Classification system] PortulacaoleraceaL., Herba Portulacae Chang Sheng in wasteland, field, vegetable garden, roadside, be distributed in all over China, south China, East China, North China, northeast, Central-South, southwestern, northwest is more.Function cures mainly: enteritis, dysentery, hematuria, urethritis, eczema, dermatitis, leucorrhea with red and white discharge and various carbuncle, furuncle, acute mastitis, bleeding hemorrhoids, venom etc.
The present invention has the effects such as anti-inflammation, heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain, effectively can prevent and treat wound infection.
In the present invention, the pharmacological function of each composition is:
Rhizoma Coptidis not only has heat clearing and damp drying, the effect of eliminating fire and detoxication, also has good antibacterial action, can resist the effectively multiple pathogenic bacteria of opposing.
Herba Duchesneae Indicae promoting blood circulation to remove blood stasis, inducing diuresis to remove edema.
Fructus Forsythiae heat-clearing and toxic substances removing, antibacterial bacteriostatic, dispersing swelling and dissipating binds.
Herba Portulacae energy reducing swelling and alleviating pain.
Be exactly more than the present invention's Chinese medicine Pharmaceutical of preventing and treating wound infection and preparation method thereof, with pure Chinese medicine for raw material, have no side effect, have no drug resistance, preparation process is simple, with low cost, time saving and energy saving, easy to use.
Beneficial effect of the present invention:
1, the present invention is with Rhizoma Coptidis, Herba Duchesneae Indicae, Fructus Forsythiae and Herba Portulacae four taste Chinese herbal medicine for raw material is prepared, and utilizes Chinese herbal medicine self effect to reach the object of control wound infection, has no side effect, have no drug resistance, be applicable to life-time service.
2, the present invention does not add any artificial synthetic additive, pure natural ecosystem.
2, preparation process is simple, does not pollute; Using method is simple, is simple and easy to use, meets Family needs; Raw material sources is wide, cheap, alleviates people's financial burden.
Detailed description of the invention
Embodiment 1
Get following raw material:
Rhizoma Coptidis 10 parts;
Herba Duchesneae Indicae 10 parts;
Fructus Forsythiae 10 parts;
Herba Portulacae 10 parts;
Preparation method is as follows:
Rhizoma Coptidis, Herba Duchesneae Indicae, YINQIAO and Herba Portulacae are pulverized, with gross weight 3-5 times of clear water water boil 20-30 minute, filter, filtering residue adds 1-2 clear water doubly, then boils 10-15 minute, merges twice filtrate, bottling, Aseptic sterilisation.Using method: be directly applied in affected part.
Embodiment 2
Get following raw material:
Rhizoma Coptidis 12.5 parts;
Herba Duchesneae Indicae 12.5 parts;
Fructus Forsythiae 15 parts;
Herba Portulacae 15 parts;
Preparation method is as follows:
Rhizoma Coptidis, Herba Duchesneae Indicae, YINQIAO and Herba Portulacae are pulverized, with gross weight 3-5 times of clear water water boil 20-30 minute, filter, filtering residue adds 1-2 clear water doubly, then boils 10-15 minute, merges twice filtrate, bottling, Aseptic sterilisation.Using method: be directly applied in affected part.
Embodiment 3
Get following raw material:
Rhizoma Coptidis 15 parts;
Herba Duchesneae Indicae 15 parts;
Fructus Forsythiae 20 parts;
Herba Portulacae 20 parts;
Preparation method is as follows:
Rhizoma Coptidis, Herba Duchesneae Indicae, YINQIAO and Herba Portulacae are pulverized, with gross weight 3-5 times of clear water water boil 20-30 minute, filter, filtering residue adds 1-2 clear water doubly, then boils 10-15 minute, merges twice filtrate, bottling, Aseptic sterilisation.Using method: be directly applied in affected part.
Application Example:
Embodiment 1,
Tan, 45 years old, millworker.In May, 2013, accidentally scalded by the machine heated when factory operates machines, go home to have wiped some Aloe, and certainly take Western medicine, within one week, have no improvement, and wound starts hemorrhage suppuration, hurt like hell.Find the present inventor, introduce through the present inventor and use embodiment 1 medicinal liquid, smear affected part every day three times, use after five days, wound is clearly better.
Embodiment 2,
Zhang, 30 years old, office's white collar.Drive electric bicycle in August, 2013 to be on duty in way and accidentally to be knocked down by other vehicles, knee scratch is serious, and wound is larger.Go hospital's simple dressing, and start the Western medicine taking doctor prescribed, after five days, still gnawing pains take no rest, and wound has started to flow out pus, red and swollen around.Two days later upon somebody's introduction, bring into use the embodiment of the present invention 2 medicinal liquid, cut out Western medicine, this formulation product is applied in affected part by every day, uses five every day, and after three days, wound stops suppurating, and starts to occur incrustation, gets better every day.
Embodiment 3,
Cai, 51 years old, housewife.Scalded by hot soup when in August, 2013 cooks, wound bubble, red and swollen around, be coated with WANHUAYOU two days ineffective, two days later upon somebody's introduction, bring into use the embodiment of the present invention 3 medicinal liquid, every day is applied in affected part, uses five every day, after three days, wound starts to occur incrustation, gets better every day.
Claims (1)
1. prevent and treat the preparation method of the traditional Chinese medicine liquid of wound infection, it is characterized in that: it is made up of the raw material of following portions by weight:
Rhizoma Coptidis 10-15 part;
Herba Duchesneae Indicae 10-15 part;
Fructus Forsythiae 10-20 part;
Herba Portulacae 10-20 part;
The preparation method of described traditional Chinese medicine liquid is: Rhizoma Coptidis, Herba Duchesneae Indicae, Fructus Forsythiae and Herba Portulacae are pulverized, boil 20-30 minute with a medicine gross weight 3-5 times clear water, filters, filtering residue adds 1-2 clear water doubly, then boils 10-15 minute, merges twice filtrate, bottling, Aseptic sterilisation, obtains product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310600043.9A CN103599205B (en) | 2013-11-25 | 2013-11-25 | Traditional Chinese medicine liquid of control wound infection and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310600043.9A CN103599205B (en) | 2013-11-25 | 2013-11-25 | Traditional Chinese medicine liquid of control wound infection and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103599205A CN103599205A (en) | 2014-02-26 |
| CN103599205B true CN103599205B (en) | 2015-11-25 |
Family
ID=50117511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310600043.9A Active CN103599205B (en) | 2013-11-25 | 2013-11-25 | Traditional Chinese medicine liquid of control wound infection and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103599205B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104096047A (en) * | 2014-03-18 | 2014-10-15 | 四川金堂海纳生物医药技术研究所 | Externally-applied detoxification ointment for treatment of poisonous snake bite wound and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101108016A (en) * | 2007-08-20 | 2008-01-23 | 陈江 | Coptis, phellodendron and scutellaria beverage for fire-purging |
| CN102018781A (en) * | 2009-09-11 | 2011-04-20 | 王文祥 | Tissue-regeneration liniment of coptis and forsythia and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101483343B1 (en) * | 2011-12-15 | 2015-01-15 | 이항종 | A composition for treating skin diseases comprising complex extract and a cosmetic and skin externals using the same |
-
2013
- 2013-11-25 CN CN201310600043.9A patent/CN103599205B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101108016A (en) * | 2007-08-20 | 2008-01-23 | 陈江 | Coptis, phellodendron and scutellaria beverage for fire-purging |
| CN102018781A (en) * | 2009-09-11 | 2011-04-20 | 王文祥 | Tissue-regeneration liniment of coptis and forsythia and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 中西医结合治疗化脓感染性皮肤病100例观察;余冰;《新医学学刊》;20081231;第5卷(第9期);第1593页左栏倒数第4段、第2节 * |
| 梅全喜.广东地产药材研究.《广东地产药材研究》.广东科技出版社,2011,(第1版),第38页. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103599205A (en) | 2014-02-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102327478B (en) | Pharmaceutical composition for treating burns and scalds and preparation method thereof | |
| CN102697961B (en) | Gynecological cleaning solution and preparation method thereof | |
| CN102357164B (en) | Medicine composition for clinical care of burns and preparation method thereof | |
| CN104940627A (en) | Traditional Chinese medicine composition for promoting wound healing, and preparation method of traditional Chinese medicine composition | |
| CN103239676B (en) | Topical pharmaceutical composition for preventing and treating bacterial vaginosis | |
| CN104784548A (en) | Traditional Chinese medicine composition for treating cough and application thereof | |
| CN102846858A (en) | Antibacterial pharmaceutical composition | |
| CN102266422A (en) | Chinese medicinal preparation for treating slight and severe chilblains and production method thereof | |
| CN103599205B (en) | Traditional Chinese medicine liquid of control wound infection and preparation method thereof | |
| CN101391065B (en) | Compound momordica seed pepper soup for treating urgent chronic pelvic inflammatory disease | |
| CN103599234B (en) | Traditional Chinese medicine liquid of control wound infection and preparation method thereof | |
| CN105560620A (en) | Trauma treatment traditional Chinese medicine preparation | |
| CN105106304A (en) | Traditional Chinese medicine compound preparation for treating gynecological inflammations and preparation method thereof | |
| CN1977894A (en) | Medicinal composition with anti-inflammation effect and its preparing method | |
| CN103599187B (en) | The Chinese herbal medicine for the treatment of mammitis of cow and nano injection liquid and preparation method thereof thereof | |
| CN101554438B (en) | Traditional Chinese medicine for curing hemorrhoids | |
| CN103599377A (en) | Traditional Chinese medicine for treating burn | |
| CN103599231B (en) | Traditional Chinese medicine liquid of control wound infection and preparation method thereof | |
| CN103610837B (en) | Traditional Chinese medicine liquid of control wound infection and preparation method thereof | |
| CN104069410A (en) | Liquid medicine for treating dermatophytosis | |
| CN103599328A (en) | Traditional Chinese medicine for treatment of pulmonary alveolar proteinosis | |
| CN103860749B (en) | A kind of preparation method treating the sick Chinese medicine composition of Ungula Sus domestica and Chinese medicine thereof | |
| CN103505593B (en) | Chinese medicinal herb formula for removing necrotic tissue and promoting tissue regeneration | |
| CN105521326A (en) | Traditional Chinese medicine for treating hebra prurigo | |
| CN1879713A (en) | A liniment for treating facial acne and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |