CN103598590A - Traditional Chinese medicine composition for decreasing blood sugar and application thereof - Google Patents
Traditional Chinese medicine composition for decreasing blood sugar and application thereof Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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Abstract
The invention relates to a traditional Chinese medicine composition for decreasing blood sugar and application thereof. The composition comprises the following components in parts by weight: 5 to 10 parts of scrophularia ningpoensis, 10 to 24 parts of astragalus membranaceus, 30 to 38 parts of radix puerariae, 30 to 40 parts of rhizoma polygonati, and 10 to 25 parts of lithocarpus polystachyus leaves. The preparation method of the traditional Chinese medicine composition comprises the step of superfine grinding by which the effective ingredients can be quickly dissolved out and absorbed by a human body. The traditional Chinese medicine composition has the effects of assisting to decrease blood sugar, comprehensively regulating physical function, treating both symptoms and root causes, and consolidating the effect.
Description
Technical field
The invention belongs to Chinese medicine health-care technical field, be specifically related to a kind of fall hypoglycemic Chinese medicine composition and application thereof.
Background technology
Diabetes are a kind ofly to take plasma glucose levels and increase the endocrine and metabolic disorders disease as feature, be a kind ofly interact with inherent cause and environmental factor, the multifactor disease jointly causing.Clinically, diabetes show typical three-many-one-little symptom, i.e. many drinks, diuresis, the symptom of eating more and losing weight, and the various complication due to it have become that patient is disabled, lethal one of the main reasons.This disease is difficult to cure, and needs of patients Long-term taking medicine is maintained blood sugar in normal range (NR) or stoped blood sugar further to raise by medicine, delays increasing the weight of and the generation of complication of the state of an illness.
At present, the treatment of diabetes is main mainly with Western medicine, as sulfonylureas and biguanides, although hypoglycemic effect is rapid, act on singlely, increase pancreas islet burden, and there is the side effects such as hypoglycemia, gastrointestinal reaction, along with the prolongation for the treatment of time, hypoglycemic effect is reduction trend, and long-term taking also can cause liver kidney toxic and side effect.
Theory of traditional Chinese medical science thinks that diabetes spp is in the category of quenching one's thirst, its interpretation of the cause, onset and process of an illness be mainly lung, stomach, the dirty the moon of kidney three thanks to scorching, calcination body fluid, disappear and burn due to water paddy.Chinese traditional herbs treatment diabetes action temperature and lasting, side effect is little, and the mechanism of action has many target spots, manifold effect, multi-functional Comprehensive Characteristics.
If filter out from Chinese medicine effectively, the hypoglycemic medicinal material of safety and par, be made into the formulation of conveniently taking, in other medicines treatment diabetes, take, can play assistant hypoglycemic, comprehensively regulating physical function, treats both principal and secondary aspect of disease, and consolidates the effect of curative effect.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of hypoglycemic Chinese medicine composition that falls, the effect that said composition can play assistant hypoglycemic, comprehensively regulating physical function, treat both principal and secondary aspect of disease, consolidates curative effect.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
Of the present inventionly fall hypoglycemic Chinese medicine composition, comprise the component of following weight proportion: 5～10 parts of radix scrophulariaes, 10～24 parts of the Radixs Astragali, 30～38 parts of the roots of kudzu vine, 30～40 parts of sealworts, 10～25 parts of manyspike tanoak leafs.
Further, of the present inventionly fall hypoglycemic Chinese medicine composition, preferably include the component of following weight proportion: 6～7 parts of radix scrophulariaes, 13～17 parts of the Radixs Astragali, 32～36 parts of the roots of kudzu vine, 34～36 parts of sealworts, 20～24 parts of manyspike tanoak leafs.Describedly fall hypoglycemic Chinese medicine composition, more preferably comprise the component of following weight proportion: 7 parts of radix scrophulariaes, 17 parts of the Radixs Astragali, 32 parts of the roots of kudzu vine, 34 parts of sealworts, 24 parts of manyspike tanoak leafs.
Above-mentioned composition is in concrete application, different depending on concrete dosage form, also can add filler, cosolvent, flavouring, bacteriostatic agent etc.
According to < < Chinese medicine voluminous dictionary > >, (Nanjing University of Traditional Chinese Medicine writes, Shanghai science tech publishing house, second edition), the mechanism of described five tastes raw medicinal material is as follows: radix scrophulariae, return lung, stomach, kidney channel, there is cool blood, nourishing Yin and falling fire, the effect of removing toxic substances, can treat warm heat disease heat and enter ying blood, body heat, polydipsia, tongue is deep red, send out spot, hectic fever due to yin labor is coughed, and dysphoria is insomnia, and constipation is hindered in Tianjin, order is puckery dim-sighted, abscess of throat, scrofula subcutaneous nodule, skin sore etc.The Radix Astragali, returns lung, the spleen channel, has invigorating qi for strengthening superficies, diuresis holder poison, and apocenosis, expelling pus and promoting granulation, weak for the deficiency of vital energy, anorexia and loose stool, the sinking of qi of middle-jiao, rushes down prolapse of the anus for a long time, the uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult bursts, and bursts and does not hold back for a long time, and flaccidity of limbs due to deficiency of blood is yellow, and interior heat is quenched one's thirst; Chronic nephritis albuminuria, diabetes.Sealwort, returns spleen, stomach warp, has Yin nourishing and lung moistening, invigorates the spleen and benefits qi, and the effect of Zishen fill fine, can treat deficiency of Yin labor and cough, xeropulmonary cough; Insufficiency of the spleen weak, the few dry of food, quenches one's thirst; Deficiency of the kidney soreness and weakness of waist and knees, impotence and seminal emission, tinnitus order is dark, poliosis, the empty win of body is thin, wind favus disease etc.The root of kudzu vine, returns spleen, stomach warp, has expelling pathogenic factors from muscles and skin and delivers, and promotes the production of body fluid to quench thirst, and rises the effect of positive antidiarrheal, cures mainly fever caused by exogenous pathogens, rigid and painful head and neck, and measles goes out not smooth from the beginning of, rash, and warm disease is thirsty, and diabete is had loose bowels, dysentery etc.Manyspike tanoak leaf, has clearing heat and detoxicatingly, reduces phlegm, dispel the wind, and step-down, main damp-heat dysentery, cough with lung heat, ulcer sores, pruitus, hypertension.
The weight proportion of described gomi herbs in said composition, the prepared slices of Chinese crude drugs that the process of take is concocted are benchmark.Said composition, when concrete application, can adopt traditional decoction form, also can be used as functional materials and adds in health food, also can be prepared as the preparation that is easy to preservation and takes.Another order of the present invention is just to protect the application of hypoglycemic Chinese medicine composition in preparing Chinese medicine preparation or health products of falling of the present invention.Particularly, the formulation of described preparation is pill, powder, tablet, capsule, granule, paste, oral liquid etc.
The present invention provides a kind of above-mentioned method that hypoglycemic Chinese medicine composition is prepared preparation of falling of utilizing below, and the method is conducive to the stripping of each medicinal material active ingredient in composition, and extraction efficiency is high, and the concentrate of preparation is also convenient to further preparation.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
Fall hypoglycemic Chinese medicine composition and prepare the method for preparation, comprise the following steps:
A, the prepared slices of Chinese crude drugs difference ultramicro grinding of getting manyspike tanoak leaf, radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort, obtain medicinal powder;
B, by the above-mentioned weight proportion that falls hypoglycemic Chinese medicine composition, the medicinal powder of getting steps A carries out ultrasonic wave or Microwave-assisted Extraction is got, and obtains extract;
C, the extract of getting step B carry out filtering with microporous membrane, concentrated, obtain concentrate for preparation and get final product.
Further, the preparation method of the prepared slices of Chinese crude drugs of described radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort comprises the following steps: get the fresh medicinal material of radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort, through cleaning, dry, after stripping and slicing, degreasing, oven dry makes.
Further, described steps A is by medicine materical crude slice ultramicro grinding to 200 order or thinner.
Ultramicro grinding described in steps A refers to that utilizing machinery or hydrokinetic method to overcome solid interior cohesiveness makes it broken, the operating technology that material particles more than millimeter can be crushed to micron, the powder obtaining thus has good dissolubility, dispersiveness, adsorptivity, chemical reactivity etc.Superfine communication technique is used for to the present invention, thus obtained drug powder, being directly used in preparation has good preparation characteristic, and for further extraction, extracted amount and the extraction efficiency of its active component also increase.
In above-mentioned preparation method, after ultramicro grinding, extract again, can improve extraction efficiency, increase the stripping of active component; And medicinal material is carried out to ungrease treatment while preparing the prepared slices of Chinese crude drugs, be conducive to the carrying out of ultramicro grinding.During concrete crushing operation, after can first pulverizing with Ordinary pulverization machine is preliminary, then be crushed to required granularity with micronizer.
It is the special roles such as cavitation that utilize ultrasonic wave to produce that ultrasonic wave described in step B extracts, the new extractive technique that contained chemical composition in medicine is extracted quickly and efficiently.Its operating process is: in container, add and extract solvent (water, ethanol or other organic solvents etc.), graininess is pulverized or be cut into Chinese medicine as required, put into and extract solvent; The bonding transducer oscillator of outer wall of container or oscillator is sealed in stainless steel box and is dropped in container; Open supersonic generator, oscillator sends ultrasonic wave to extracting in solvent, ' cavitation effect ' that ultrasonic wave produces in extracting solvent and mechanism one side be the cell membrane of broken medicinal material effectively, make active ingredient be free state and dissolve in to extract in solvent, can accelerate to extract on the other hand the molecular motion of solvent, make to extract solvent and contact fast with the active ingredient in medicinal material, mutually fused, mixing.Ultrasonic wave extracts with it and extracts the extraction that temperature is low, unique advantage that recovery rate is high, extraction time is short is widely used in Chinese medicine and various animal and plant effective contents, is to substitute tradition shearing process to realize modern high technology means efficient, that energy-saving and environmental protection formula is extracted.Described microwave auxiliary extraction (MAE), it is microwave abstracting, according to the difference of different material absorption microwave ability, some region of base matter or some component in extraction system selectively to be heated, thereby it is separated from matrix or system to make to be extracted material, enter into that dielectric constant is less, the extractant of microwave absorption capacity relative mistake, reach the object of extraction.The present invention adopts ultrasonic wave or Microwave-assisted Extraction to get, due to the advantage of the method itself, and the synergy of the present composition in leaching process, can significantly improve recovery rate and extraction efficiency.
Filtering with microporous membrane described in step C claims again secondary filter, mainly for separating of submicron particles, the means of current most widely used a kind of compartment analysis subparticle and ultra-clean degerming, have simple to operate, floor space is little, in processing procedure without phase transformation and can not produce the advantages such as new polluter, good separating effect.In method of the present invention, can first to extract, carry out carrying out again filtering with microporous membrane after coarse filtration.
Extract after filtering can concentrate by modes such as atmospheric evaporation, reduction vaporization, thin film evaporation.The concentrate obtaining can carry out preparation according to the conventional method of Chinese medicine preparation, finally makes the various formulations such as pill, powder, tablet, capsule, granule.According to the standby concrete formulation of drawing up, can add necessary diluent, adhesive, disintegrant, lubricant etc.
The present invention also has an object to be to provide a kind of above-mentioned method that hypoglycemic Chinese medicine composition is prepared capsule of falling of utilizing, and the method operation is simple, and product is stored and taken all very convenient.The technical scheme adopting is:
Fall hypoglycemic Chinese medicine composition and prepare the method for capsule, comprise the following steps:
By the above-mentioned weight proportion that falls hypoglycemic Chinese medicine composition, get respectively the prepared slices of Chinese crude drugs ultramicro grinding of manyspike tanoak leaf, radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort, cross 200 mesh sieves, obtain medicinal powder batch mixing, encapsulated, obtain.
Further, the preparation method of the prepared slices of Chinese crude drugs of described radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort comprises the following steps: get the fresh medicinal material of radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort, through cleaning, dry, after stripping and slicing, degreasing, oven dry makes.
The ultramicro grinding medicinal powder granularity that said method obtains is suitable, has both been conducive to the absorption of human body, has again good mobility, is convenient to preparation operation.As the further improvement of said method, preferably capsule is prepared into the capsule containing medicinal ingredient 0.3g/ grain.
Beneficial effect of the present invention: of the present inventionly fall hypoglycemic Chinese medicine composition, follow the principle of tcm syndrome differentiation and treatment, all medicine phases and, there is nourishing kidney-YIN, fall hypoglycemic effect, integration of drinking and medicinal herbs, cheap.By itself and other, treat the medicine of diabetes and take simultaneously, particularly, as adjuvant drug or the health products of chemical classes antidiabetic drug, can play assistant hypoglycemic, comprehensively regulating physical function, treats both principal and secondary aspect of disease, and consolidates the effect of curative effect; For having diabetes family history or three high diabetes vulnerable crowds, take it as health products the effect that can play prevention diabetes.This falls hypoglycemic Chinese medicine composition can be prepared as multiple formulation, and its preparation method adopts again superfine communication technique, makes the product obtaining have good dissolubility, dispersiveness, adsorptivity, chemical reactivity etc., is easy to follow-up preparation operation and absorption of human body.Especially as stated above the capsule of preparing, operation is simple, and product is stored and is taken all very convenient.
The specific embodiment
In order to make the object, technical solutions and advantages of the present invention clearer, below the preferred embodiments of the present invention and contrast experiment's example are described in detail.
Embodiment 1
Press row weight proportion and prepare each component: radix scrophulariae 10g, Radix Astragali 24g, root of kudzu vine 30g, sealwort 30g, manyspike tanoak leaf 25g.Each component is tentatively pulverized respectively, carries out ultramicro grinding after pulverizing again, crosses 200 mesh sieves, and batch mixing, is pressed into 0.25g/ sheet, and film coating, obtains.
Embodiment 2
Press row weight proportion and prepare each component: radix scrophulariae 6g, Radix Astragali 18g, root of kudzu vine 36g, sealwort 34g, manyspike tanoak leaf 23g.Each component is tentatively pulverized respectively, carries out ultramicro grinding after pulverizing again, crosses 200 mesh sieves, batch mixing, and packing, sterilizing, obtains powder.
Embodiment 3
Press row weight proportion and prepare each component: radix scrophulariae 7g, Radix Astragali 14g, root of kudzu vine 36g, sealwort 36g, manyspike tanoak leaf 22g.Each component is tentatively pulverized respectively, carries out ultramicro grinding after pulverizing again, crosses 200 mesh sieves, batch mixing, and encapsulated 0.3g/ grain, obtains.
Embodiment 4
Press row weight proportion and prepare each component: radix scrophulariae 5g, Radix Astragali 13g, root of kudzu vine 38g, sealwort 40g, manyspike tanoak leaf 20g.Each component is tentatively pulverized respectively, carries out ultramicro grinding after pulverizing again, crosses 200 mesh sieves, batch mixing, and encapsulated 0.3g/ grain, obtains.
Embodiment 5
Press row weight proportion and prepare each component: radix scrophulariae 700g, Radix Astragali 1700g, root of kudzu vine 3200g, sealwort 3400g, manyspike tanoak leaf 2400g.Each component is tentatively pulverized respectively, carries out ultramicro grinding after pulverizing again, crosses 200 mesh sieves, batch mixing, and encapsulated 0.3g/ grain, obtains.
Embodiment 6
Press row weight proportion and prepare each component: radix scrophulariae 500g, Radix Astragali 1000g, root of kudzu vine 3000g, sealwort 3000g, manyspike tanoak leaf 1000g.Each component is tentatively pulverized respectively, carries out ultramicro grinding after pulverizing again, crosses 200 mesh sieves, adds filler starch 2900g, batch mixing, and encapsulated 0.3g/ grain, obtains.
Embodiment 7
Get the fresh medicinal material of radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort, through cleaning, dry, after stripping and slicing, degreasing, dry and make the prepared slices of Chinese crude drugs.Get again the prepared slices of Chinese crude drugs of manyspike tanoak leaf, and the prepared slices of Chinese crude drugs of the aforementioned radix scrophulariae making, the Radix Astragali, the root of kudzu vine and sealwort difference ultramicro grinding, medicinal powder obtained.Press row weight proportion and take each medicinal powder: radix scrophulariae 10g, Radix Astragali 24g, root of kudzu vine 30g, sealwort 30g, manyspike tanoak leaf 25g, all medicinal powder is mixed, proceeding to model is in the ultrosonic extractor of SBL-ultrasonic wave (Ningbo Xin Zhi biotechnology Co., Ltd), add water 2000ml, ultrasonic power 600W, ultrasonic extraction 1 hour.After extraction completes, suction filtration obtains filtrate, then obtains filtrate with the filtering with microporous membrane of 0.45 μ m.Filtrate evaporated under reduced pressure after filtering with microporous membrane is concentrated into 500ml, adds white granulated sugar 250g, and dissolving mixes, and sterilizing obtains the syrup of this Chinese medicine composition.
Contrast experiment's example 1
Accept out-patient's 150 examples for medical treatment, the male sex 90 people wherein, women 60 people, 50 years old mean age, are divided into five groups of A, B1, B2, C1, C2, every group of 30 people: A group, as reference group, is taken 1 of starch capsule, 3 times/day at random; B1 and B2 group is taken respectively 1 of the capsule of embodiment 5 and embodiment 6 preparations, 3 times/day; C1 and C2 group is taken respectively 2 of the capsules of embodiment 5 and embodiment 6 preparations, 3 times/day.
All patients take continuously capsule and stop using, then observe 20 days afterwards for 30 days.Respectively take capsule first 1 day, take capsule after the 30th day and take capsule after within the 50th day, detect fasting blood-glucose index.Result represents by surveyed index average ± standard deviation, and the statistical method of application t check is analyzed result, and P < 0.05 thinks tool significance.Test result is as follows:
Table 1 patient takes the test result of capsule front and back fasting blood-glucoses (mmol/L)
| Group | Take capsule situation | Take first 1 day | Take latter the 30th day | Take latter the 50th day |
| A group | 1 of starch capsule, 3 times/day | 11.9±0.8 | 12.8±1.0 | 12.9±0.8 |
| B1 group | 1 of embodiment 5 capsule, 3 times/day | 12.0±1.1 | 8.6±1.0* | 9.6±1.4* |
| B2 group | 1 of embodiment 6 capsule, 3 times/day | 12.1±0.9 | 9.4±1.2* | 9.9±1.6* |
| C1 group | 2 of embodiment 5 capsules, 3 times/day | 12.2±1.3 | 8.7±1.1* | 9.8±1.5* |
| C2 group | 2 of embodiment 6 capsules, 3 times/day | 11.9±1.0 | 8.6±0.9* | 9.5±1.3* |
Note *: with take front comparison: P < 0.05, its otherness has statistical significance.
As shown in Table 1, diabetes patient is in the situation that refusing to obey other hypoglycemic medicine, only take the present invention and fall capsule prepared by hypoglycemic Chinese medicine composition, at the blood glucose test result of the 30th day and the 50th day all than there being obvious decline before taking capsule, and after drug withdrawal the 50th day, still there is not significantly bounce-back in blood glucose test result.In addition, from the data of B1 and B2, C1 and C2, take the capsule that embodiment 6 prepared according to composition minority component and still there is the curative effect suitable with embodiment 5 capsules.Therefore, of the present invention to fall hypoglycemic Chinese medicine composition curative effect reliable, has and obviously fall hypoglycemic function, and the generation of diabetes and development are had to prevention effect.
Contrast experiment's example 2
Accept out-patient's 60 examples for medical treatment, the male sex 34 people wherein, women 26 people, 50 years old mean age, be divided at random two groups of A, B, every group of 30 people: A, B group all taken metformin hydrochloride tablet, each 0.25g, 3 times/day; B group is also taken 1 of the capsule of embodiment 5 preparations, 3 times/day simultaneously.
All patients take continuously capsule and stop using, then observe 20 days afterwards for 30 days.Respectively taking capsule first 1 day, take capsule after the 30th day and take capsule after within the 50th day, detect, Detection of content comprises fasting blood-glucose.Result represents by surveyed index mean ± standard deviation, and the statistical method of application t check is analyzed result, and P < 0.05 thinks tool significance.Test result is as follows:
The contrast test result of fasting blood-glucose (mmol/L) after table 2 patient drug combination
Note * and take front comparison: P < 0.05, its otherness has statistical significance.
As shown in Table 2, diabetes patient, in the situation that taking other hypoglycemic medicine, also takes the present invention and falls capsule prepared by hypoglycemic Chinese medicine composition, hypoglycemic effect better, more stable.
Finally explanation is, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although the present invention is had been described in detail with reference to preferred embodiment, those of ordinary skill in the art is to be understood that, can modify or be equal to replacement technical scheme, and not departing from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of claim scope of the present invention.
Claims (10)
1. fall hypoglycemic Chinese medicine composition, comprise the component of following weight proportion: 5～10 parts of radix scrophulariaes, 10～24 parts of the Radixs Astragali, 30～38 parts of the roots of kudzu vine, 30～40 parts of sealworts, 10～25 parts of manyspike tanoak leafs.
2. according to claim 1ly fall hypoglycemic Chinese medicine composition, it is characterized in that: the component that comprises following weight proportion: 6～7 parts of radix scrophulariaes, 13～17 parts of the Radixs Astragali, 32～36 parts of the roots of kudzu vine, 34～36 parts of sealworts, 20～24 parts of manyspike tanoak leafs.
3. according to claim 1ly fall hypoglycemic Chinese medicine composition, it is characterized in that: the component that comprises following weight proportion: 7 parts of radix scrophulariaes, 17 parts of the Radixs Astragali, 32 parts of the roots of kudzu vine, 34 parts of sealworts, 24 parts of manyspike tanoak leafs.
4. described in claims 1 to 3 any one the application of hypoglycemic Chinese medicine composition in preparing Chinese medicine preparation or health products fall.
5. the Chinese medicine preparation that falls hypoglycemic Chinese medicine composition according to claim 4, is characterized in that: the formulation of described preparation is pill, powder, tablet, capsule or granule.
6. utilize the method that hypoglycemic Chinese medicine composition is prepared preparation of falling described in claim 1 to 3 any one, comprise the following steps:
A, the prepared slices of Chinese crude drugs difference ultramicro grinding of getting manyspike tanoak leaf, radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort, obtain medicinal powder;
B, by weight proportion described in claims 1 to 3 any one, the medicinal powder of getting steps A carries out ultrasonic wave or Microwave-assisted Extraction is got, and obtains extract;
C, the extract of getting step B carry out filtering with microporous membrane, concentrated, obtain concentrate for preparation and get final product.
7. according to claim 6 the method that hypoglycemic Chinese medicine composition is prepared preparation falls, it is characterized in that: the preparation method of the prepared slices of Chinese crude drugs of described radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort comprises the following steps: the fresh medicinal material of getting radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort, through cleaning, dry, after stripping and slicing, degreasing, oven dry makes.
8. according to the method that hypoglycemic Chinese medicine composition is prepared preparation of falling described in claim 6 or 7, it is characterized in that: described steps A is by medicine materical crude slice ultramicro grinding to 200 order or thinner.
9. utilize the method that hypoglycemic Chinese medicine composition is prepared capsule of falling described in claim 1 to 3 any one, comprise the following steps:
By weight proportion described in claims 1 to 3 any one, get respectively the prepared slices of Chinese crude drugs ultramicro grinding of manyspike tanoak leaf, radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort, cross 200 mesh sieves, obtain medicinal powder batch mixing, encapsulated, obtain.
10. according to claim 9 the method that hypoglycemic Chinese medicine composition is prepared capsule falls, it is characterized in that: the preparation method of the prepared slices of Chinese crude drugs of described radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort comprises the following steps: the fresh medicinal material of getting radix scrophulariae, the Radix Astragali, the root of kudzu vine and sealwort, through cleaning, dry, after stripping and slicing, degreasing, oven dry makes.
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Effective date of registration: 20181218 Address after: 409800 Building A, Phase 2, Banxi Light Industrial Park, Youyang County, Chongqing Patentee after: Chongqing Wanyuan Pharmaceutical Co., Ltd. Address before: No. 34 Nanshan Road, Nanshan Street, Nanan District, Chongqing 400065 Patentee before: Chongqing Academy of Chinese Materia Medica |