CN103584076B - 一种保健食品的组合物 - Google Patents
一种保健食品的组合物 Download PDFInfo
- Publication number
- CN103584076B CN103584076B CN201210287795.XA CN201210287795A CN103584076B CN 103584076 B CN103584076 B CN 103584076B CN 201210287795 A CN201210287795 A CN 201210287795A CN 103584076 B CN103584076 B CN 103584076B
- Authority
- CN
- China
- Prior art keywords
- fructus
- parts
- compositions
- taurine
- poria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 37
- 235000013402 health food Nutrition 0.000 title claims abstract description 27
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 42
- 241000628997 Flos Species 0.000 claims abstract description 23
- 229960003080 taurine Drugs 0.000 claims abstract description 20
- 239000003814 drug Substances 0.000 claims abstract description 16
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 15
- 239000010642 eucalyptus oil Substances 0.000 claims abstract description 14
- 229940044949 eucalyptus oil Drugs 0.000 claims abstract description 14
- NOOLISFMXDJSKH-UHFFFAOYSA-N p-menthan-3-ol Chemical compound CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 11
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 11
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims abstract description 11
- 229930006000 Sucrose Natural products 0.000 claims abstract description 11
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 11
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 11
- 239000002674 ointment Substances 0.000 claims abstract description 10
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 9
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 238000000605 extraction Methods 0.000 claims abstract description 6
- 238000010438 heat treatment Methods 0.000 claims abstract description 6
- 238000001816 cooling Methods 0.000 claims abstract description 5
- 238000001802 infusion Methods 0.000 claims abstract description 5
- 238000002156 mixing Methods 0.000 claims abstract description 5
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract 2
- 238000004806 packaging method and process Methods 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 claims 1
- 230000036039 immunity Effects 0.000 abstract description 14
- 238000004140 cleaning Methods 0.000 abstract description 11
- 230000002708 enhancing effect Effects 0.000 abstract description 10
- 230000036541 health Effects 0.000 abstract description 6
- 235000013305 food Nutrition 0.000 abstract description 2
- 230000006870 function Effects 0.000 description 13
- 230000000694 effects Effects 0.000 description 6
- 208000002193 Pain Diseases 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 230000036407 pain Effects 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 4
- 201000007100 Pharyngitis Diseases 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 210000000867 larynx Anatomy 0.000 description 4
- 230000000144 pharmacologic effect Effects 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 239000003826 tablet Substances 0.000 description 4
- 241000193830 Bacillus <bacterium> Species 0.000 description 3
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 241001570521 Lonicera periclymenum Species 0.000 description 3
- 206010068319 Oropharyngeal pain Diseases 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000000242 pagocytic effect Effects 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 2
- DANYIYRPLHHOCZ-UHFFFAOYSA-N 5,7-dihydroxy-4'-methoxyflavone Chemical compound C1=CC(OC)=CC=C1C1=CC(=O)C2=C(O)C=C(O)C=C2O1 DANYIYRPLHHOCZ-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 206010017553 Furuncle Diseases 0.000 description 2
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 206010036790 Productive cough Diseases 0.000 description 2
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 2
- 210000001744 T-lymphocyte Anatomy 0.000 description 2
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000001754 anti-pyretic effect Effects 0.000 description 2
- 239000002221 antipyretic Substances 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 229940046011 buccal tablet Drugs 0.000 description 2
- 239000006189 buccal tablet Substances 0.000 description 2
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 2
- 235000001368 chlorogenic acid Nutrition 0.000 description 2
- 229940074393 chlorogenic acid Drugs 0.000 description 2
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 2
- 231100000749 chronicity Toxicity 0.000 description 2
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 229930003944 flavone Natural products 0.000 description 2
- 150000002212 flavone derivatives Chemical class 0.000 description 2
- 235000011949 flavones Nutrition 0.000 description 2
- 235000013373 food additive Nutrition 0.000 description 2
- 239000002778 food additive Substances 0.000 description 2
- 210000003026 hypopharynx Anatomy 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- LRDGATPGVJTWLJ-UHFFFAOYSA-N luteolin Natural products OC1=CC(O)=CC(C=2OC3=CC(O)=CC(O)=C3C(=O)C=2)=C1 LRDGATPGVJTWLJ-UHFFFAOYSA-N 0.000 description 2
- 235000009498 luteolin Nutrition 0.000 description 2
- IQPNAANSBPBGFQ-UHFFFAOYSA-N luteolin Chemical compound C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(O)C(O)=C1 IQPNAANSBPBGFQ-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 2
- CWVRJTMFETXNAD-BMNNCGMMSA-N (1s,3r,4s,5r)-3-[(e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylic acid Chemical compound O[C@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-BMNNCGMMSA-N 0.000 description 1
- HOMSOWZTBJWNHP-UHFFFAOYSA-N 5-chlorothiadiazole Chemical compound ClC1=CN=NS1 HOMSOWZTBJWNHP-UHFFFAOYSA-N 0.000 description 1
- 206010002953 Aphonia Diseases 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 235000014469 Bacillus subtilis Nutrition 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 241000131317 Capitulum Species 0.000 description 1
- 241000208828 Caprifoliaceae Species 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 241000186216 Corynebacterium Species 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 206010030302 Oliguria Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 241000013557 Plantaginaceae Species 0.000 description 1
- 241000961970 Plantago depressa Species 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 241000576755 Sclerotia Species 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000193998 Streptococcus pneumoniae Species 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 206010043458 Thirst Diseases 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 235000009962 acacetin Nutrition 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000003035 anti-peroxidant effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 210000003719 b-lymphocyte Anatomy 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000008827 biological function Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 235000001465 calcium Nutrition 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 206010013023 diphtheria Diseases 0.000 description 1
- 150000004141 diterpene derivatives Chemical class 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 239000010685 fatty oil Substances 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 229930182486 flavonoid glycoside Natural products 0.000 description 1
- 150000007955 flavonoid glycosides Chemical class 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229960000367 inositol Drugs 0.000 description 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- KRZBCHWVBQOTNZ-DLDRDHNVSA-N isochlorogenic acid Natural products O[C@@H]1[C@H](C[C@@](O)(C[C@H]1OC(=O)C=Cc2ccc(O)c(O)c2)C(=O)O)OC(=O)C=Cc3ccc(O)c(O)c3 KRZBCHWVBQOTNZ-DLDRDHNVSA-N 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 230000037356 lipid metabolism Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- VDYCLYGKCGVBHN-UHFFFAOYSA-N pachymaic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC(=C)C(C)C)C(O)=O)C(O)CC21C VDYCLYGKCGVBHN-UHFFFAOYSA-N 0.000 description 1
- SRDNLMOBFKJOSD-UHFFFAOYSA-N pachymic acid Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C(O)=O)C(O)CC21C SRDNLMOBFKJOSD-UHFFFAOYSA-N 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 235000014786 phosphorus Nutrition 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 229960001285 quercetin Drugs 0.000 description 1
- 235000005875 quercetin Nutrition 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 210000003079 salivary gland Anatomy 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明涉及一种保健食品的组合物，具体是指一种同时具有清咽和增强免疫力功能保健食品的组合物。它是由以下原料和重量份数组成：金银花25-30份、青果25-30份、野菊花15-20份、车前草10-15份、茯苓10-15份、罗汉果7-15份、乌梅3-5份、牛磺酸3-5份、白砂糖750份、麦芽糖饴260份、麦芽糊精20份、薄荷脑3-5份、桉叶油0.5份；取金银花、青果、野菊花、车前草、茯苓、罗汉果、乌梅置提取锅中加水加热煮沸提取三次得药汁，浓缩成含水约50％得稠膏，加入牛磺酸混匀得药膏；将白砂糖、麦芽糖饴、麦芽糊精置熬糖锅中加水熬煮至145℃停止加热，加入药膏抽真空至0.08MPa得糖膏，置冷却台上加入薄荷脑、桉叶油混匀，压片、包装得成品。
Description
技术领域
本发明涉及一种保健食品的组合物，具体是指一种同时具有清咽和增强免疫力保健功能的清咽含片保健食品的组合物。
技术背景
咽部不适是人们的常见病，而且随着人体的免疫力下降，抗病能力低下，咽部不适越凸显频繁性、反复性、顽固性和长期性，本发明是以根本上增强人体免疫力来组方预防、治疗咽炎，在调理咽喉的常用组方中添加适量“牛磺酸”，使产品更凸显其增强免疫力的功能而加强了清咽的功能。同时，采用保健食品的原料组方，避免了药物毒副作用，适合于人们长期食用，以对咽喉的保护和调理。本发明配方合理、剂型合适、生产工艺成熟，而且产品口感好、质量稳定。
发明内容
本发明的目的是提供一种保健食品的组合物，特别是一种同时具有清咽和增强免疫力保健功能的清咽含片保健食品的组合物。
本发明的目的是这样实现的，一种保健食品的组合物，特别是一种同时具有清咽和增强免疫力保健功能的清咽含片保健食品的组合物，其包括以下原料和重量份数制成：金银花25-30份、青果25-30份、野菊花15-20份、车前草10-15份、茯苓10-15份、罗汉果7-15份、乌梅3-5份、牛磺酸3-5份、白砂糖750份、麦芽糖饴260份、麦芽糊精20份、薄荷脑3-5份、桉叶油0.5份；按配方比例先取金银花、青果、野菊花、车前草、茯苓、罗汉果、乌梅置提取取锅中加水适量加热煮沸提取三次即得药汁，药汁浓缩成含水约50％得稠膏，加入牛磺酸混合均匀得药膏备用；然后将白砂糖、麦芽糖饴、麦芽糊精置熬糖锅中加适量水边加热边搅拌熬煮至温度达145℃，停止加热，加入药膏，抽真空至真空度达0.08MPa即得糖膏，将糖膏出锅置于冷却台上加入薄荷脑、桉叶油混合均匀即得混合糖膏，压片、包装即得成品。
本发明制成的产品为含片型硬质糖果保健食品，产品具有清咽润喉和增加免疫力的功能，用于人体免疫力低下而引起的长期性、反复性、顽固性的干、痒、粘、肿、痛等咽部不适，本产品无毒副作用，适合于人们长期食用来达到保健咽喉的作用。含食，每日数次，每次1-2片。
具体实施方式
本发明公开了一种保健食品的组合物，是指一种同时具有清咽和增强免疫力保健功能的清咽含片保健食品的组合物，其包括以下原料和重量份数组成：金银花25-30份、青果25-30份、野菊花15-20份、车前草10-15份、茯苓10-15份、罗汉果7-15份、乌梅3-5份、牛磺酸3-5份、白砂糖750份、麦芽糖饴260份、麦芽糊精20份、薄荷脑3-5份、桉叶油0.5份。
本发明的较佳实施例中主要功效原料金银花、青果、野菊花、车前草、茯苓、罗汉果、乌梅、牛磺酸、薄荷脑、桉叶油进行阐述，以使本发明的优点和特征能更易于被本领域技术人员领会和理解，从而有利于对本发明的保护。
本发明一种保健食品的组合物所述的金银花为忍冬科植物忍冬的干燥花蕾或带初开的花，具有清热解毒、凉散风热的功能，用于痈肿疔疮、喉痹、丹毒、热毒血痢、风热感冒、温病发热等。花蕾中含有木犀草素(黄酮类)、肌醇、绿原酸和异绿原酸，它们是金银花的抗菌有效成分。《中药大辞典》[临床报道]降低人群咽喉部带菌率，可用于上呼吸道感染、扁桃体炎、流行性感冒等。实验证明，金银花还能抗炎、解热、加强防御功能、促进白细胞吞噬功能。
本发明一种保健食品的组合物所述的青果为橄榄科植物橄榄的干燥成熟果实，具有清热、利咽、生津、解毒的功能，用于咽喉肿痛、咳嗽、烦渴等。青果的化学成分主要含蛋白质、脂肪、碳水化合物、维生素、钙、磷、铁。现代研究证明：青果能兴奋唾液腺增加唾液的分泌而达到清咽润喉的目的。传统医药认为青果为喉科要药。
本发明一种保健食品的组合物所述的野菊花为菊科植物野菊的干燥头状花序，具有清热解毒的功能，用于疔疮痈肿、目赤肿痛等。其化学成分含挥发油、多种黄酮、绿原酸及二萜类成分等，多种黄酮包括刺槐素、木犀草素、槲皮素等。生理研究具有清咽润喉(抗菌抗病毒作用)，用于风热感冒、咽喉肿痛等，药理研究证实其具有抗菌、促进吞噬细胞的吞噬功能。
本发明一种保健食品的组合物所述的车前草为车前科植物车前或平车前的干燥全草，具有清热利尿、祛痰、凉血、解毒的功能，用于痰热咳嗽、痈肿疮毒。《中药大辞典》载：车前草的药理作用具有①祛痰作用，麻醉猫口服车前草煎剂1g/kg，可使呼吸道粘液分泌明显增加而稀释痰液；②抗炎作用，大鼠口服车前煎剂0.5～1g/kg，对由甲醛及右旋糖酐引起的炎性水肿，有明显抑制作用；③临床报道用于慢性气管炎总有效率达80％以上。
本发明一种保健食品的组合物所述的罗汉果为葫芦科植物罗汉果的干燥果实，性味甘凉，归肺、大肠经，具有清热润肺、滑肠通便的功能，用于肺火燥咳，咽痛失音，肠燥便秘。罗汉果含三萜苷、黄酮苷、脂肪油、维生素C等。
本发明一种保健食品的组合物所述的乌梅为蔷薇科植物梅的干燥近成熟果实。性味酸、涩平，归肝、脾、肺、大肠经，具有敛肺、涩肠、生津功能，用于肺虚久咳。《中药大辞典》药理作用“有①抗菌作用：体外实验证明水煎剂1：1，对白喉杆菌、葡萄球菌、枯草杆菌、肺炎球菌皆有抑制作用，对于大肠杆菌、痢疾杆菌、变形杆菌、伤寒和副伤寒杆菌、绿脓杆菌、霍乱孤菌等肠内致病菌也有效。②抗过敏作用。”相关报道：乌梅的酸性物质还可帮助调节产品有适宜的滋味。
本发明一种保健食品的组合物所述的茯苓为多孔菌科真菌茯苓的干燥菌核，传统中医药认为茯苓甘、淡，具有利水渗湿、健脾宁心之功效，用于水肿尿少、痰多眩悸、脾虚食少、便溏泄泻、心神不安、惊悸失眠等。化学成分主要为茯苓多糖、茯苓酸。茯苓多糖具有增强免疫力的生理功能；能激活淋巴T细胞和B细胞、抗胸腺萎缩、抗脾脏增大，增强巨噬细胞吞噬能力等作用。
本发明一种保健食品的组合物所述的牛磺酸：牛磺酸最初是从牛胆汁中发现的，又称牛胆酸、牛胆素，学名为2-氨基乙磺酸，是一种非蛋白的氨基酸，是人体必不可少的一种营养成分，现多为人工合成，为白色结晶粉末，无臭，微酸，对酸、碱、热稳定，易溶于水，不溶于乙醇，属于食品添加剂和营养强化剂。近代研究证明，牛磺酸具有维持组织渗透压、稳定细胞膜、调节细胞内钙平衡、抗脂质过氧化、促进脂肪代谢、保护细胞、增强免疫力等广泛的生物学功能；大量的医学研究证实牛磺酸能提高免疫能力，能改善T细胞和淋巴细胞增殖等作用，药理研究表明牛磺酸具有明显的镇痛、解热和消炎作用。
本发明一种保健食品的组合物所述的薄荷脑、桉叶油：为食品添加剂中的天然香料，能使产品有适宜的香气和滋味，另外薄荷脑还可使咽部有清凉舒适感，以减轻其不适及疼痛，桉叶油还有抗菌消炎之作用，可以减轻咽喉疼痛感。
实施例1：一种保健食品，它是指一种同时具有清咽和增强免疫力的含片保健食品，是由以下原料及重量份数制成：金银花25份、青果25份、野菊花15份、车前草10份、茯苓10份、罗汉果7份、乌梅3份、牛磺酸3份、白砂糖750份、麦芽糖饴260份、麦芽糊精20份、薄荷脑3份、桉叶油0.5份；按配方比例先取金银花、青果、野菊花、车前草、茯苓、罗汉果、乌梅置提取取锅中加水适量加热煮沸提取三次即得药汁，药汁浓缩成含水约50％得稠膏，加入牛磺酸混合均匀得药膏备用；然后将白砂糖、麦芽糖饴、麦芽糊精置熬糖锅中加适量水边加热边搅拌熬煮至温度达145℃，停止加热，加入药膏，抽真空至真空度达0.08MPa即得糖膏，将糖膏出锅置于冷却台上加入薄荷脑、桉叶油混合均匀即得混合糖膏，压片、包装即得成品。
实施例2：一种保健食品，它是指一种同时是指具有清咽和增强免疫力的含片保健食品，是由以下原料及重量份数制成：金银花30份、青果30份、野菊花20份、车前草15份、茯苓15份、罗汉果15份、乌梅5份、牛磺酸5份、白砂糖750份、麦芽糖饴260份、麦芽糊精20份、薄荷脑5份、桉叶油0.5份；按配方比例先取金银花、青果、野菊花、车前草、茯苓、罗汉果、乌梅置提取取锅中加水适量加热煮沸提取三次即得药汁，药汁浓缩成含水约50％得稠膏，加入牛磺酸混合均匀得药膏备用；然后将白砂糖、麦芽糖饴、麦芽糊精置熬糖锅中加适量水边加热边搅拌熬煮至温度达145℃，停止加热，加入药膏，抽真空至真空度达0.08MPa即得糖膏，将糖膏出锅置于冷却台上加入薄荷脑、桉叶油混合均匀即得混合糖膏，压片、包装即得成品。
Claims (1)
1.一种保健食品的组合物，其特征在于，它是由以下重量份数的原料制成：金银花25-30份、青果25-30份、野菊花15-20份、车前草10-15份、茯苓10-15份、罗汉果7-15份、乌梅3-5份、牛磺酸3-5份、白砂糖750份、麦芽糖饴260份、麦芽糊精20份、薄荷脑3-5份、桉叶油0.5份；
所述的组合物按以下方法制备：按配方比例先取金银花、青果、野菊花、车前草、茯苓、罗汉果、乌梅置提取锅中加水加热煮沸提取三次即得药汁，药汁浓缩成含水50％的稠膏，加入牛磺酸混合均匀得药膏备用；然后将白砂糖、麦芽糖饴、麦芽糊精置熬糖锅中加水，边加热边搅拌熬煮至温度达145℃，停止加热，加入药膏，抽真空至真空度达0.08MPa即得糖膏，将糖膏出锅置于冷却台上加入薄荷脑、桉叶油混合均匀即得混合糖膏，压片、包装即得成品。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210287795.XA CN103584076B (zh) | 2012-08-14 | 2012-08-14 | 一种保健食品的组合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210287795.XA CN103584076B (zh) | 2012-08-14 | 2012-08-14 | 一种保健食品的组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103584076A CN103584076A (zh) | 2014-02-19 |
| CN103584076B true CN103584076B (zh) | 2016-06-22 |
Family
ID=50074560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210287795.XA Active CN103584076B (zh) | 2012-08-14 | 2012-08-14 | 一种保健食品的组合物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103584076B (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111317054A (zh) * | 2018-12-14 | 2020-06-23 | 林东和 | 具有预防感冒效果的组合物及其制法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1318378A (zh) * | 2000-04-20 | 2001-10-24 | 陶临风 | 治疗热症的中成药 |
| CN1736434A (zh) * | 2004-08-19 | 2006-02-22 | 鄂尔多斯市蒙兴科技开发有限责任公司 | 甘草爽喉片的药物及其制备方法 |
| CN101690584A (zh) * | 2009-09-07 | 2010-04-07 | 北京同仁堂健康药业股份有限公司 | 一种清咽的功能食品和药物及其制备方法 |
| CN102233093A (zh) * | 2010-04-26 | 2011-11-09 | 朱奕斐 | 清嗓喉宝 |
| CN102579686A (zh) * | 2011-12-06 | 2012-07-18 | 西安泰科迈医药科技有限公司 | 一种中药含片及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080101848A (ko) * | 2008-10-30 | 2008-11-21 | 김광수 | 숙취예방 및 해소를 위한 생약 추출물 및 이를 이용한 기능성 식품 |
-
2012
- 2012-08-14 CN CN201210287795.XA patent/CN103584076B/zh active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1318378A (zh) * | 2000-04-20 | 2001-10-24 | 陶临风 | 治疗热症的中成药 |
| CN1736434A (zh) * | 2004-08-19 | 2006-02-22 | 鄂尔多斯市蒙兴科技开发有限责任公司 | 甘草爽喉片的药物及其制备方法 |
| CN101690584A (zh) * | 2009-09-07 | 2010-04-07 | 北京同仁堂健康药业股份有限公司 | 一种清咽的功能食品和药物及其制备方法 |
| CN102233093A (zh) * | 2010-04-26 | 2011-11-09 | 朱奕斐 | 清嗓喉宝 |
| CN102579686A (zh) * | 2011-12-06 | 2012-07-18 | 西安泰科迈医药科技有限公司 | 一种中药含片及其制备方法 |
Non-Patent Citations (1)
| Title |
|---|
| 清咽利咽合剂的质量标准研究;郑弘，等;《中国实验方剂学杂志》;20110131;第17卷(第2期);第91-92页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103584076A (zh) | 2014-02-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102578671B (zh) | 一种解酒保肝植物营养饮料及其制造方法 | |
| CN102397176A (zh) | 一种中药含漱液及其制法 | |
| CN103585433A (zh) | 一种治疗口腔溃疡的中药组合物 | |
| CN106266898A (zh) | 一种益气补肾、抗衰老的复方制剂及其制备方法 | |
| CN103182023A (zh) | 一种治疗慢性咽炎的药物及其制备方法 | |
| CN102068480A (zh) | 一种清暑解毒的食药两用复方制剂 | |
| CN104096154A (zh) | 一种治疗口腔溃疡的中药组合物 | |
| CN100428947C (zh) | 一种防治急慢性咽喉炎的保健食品及其制备方法 | |
| CN101438818B (zh) | 一种清热祛火的保健食品 | |
| CN102488814B (zh) | 治疗奶牛乳房炎的中药组合物 | |
| CN107362292A (zh) | 一种具有改善女性生殖泌尿系统炎症的组合物、制备方法及应用 | |
| CN103584076B (zh) | 一种保健食品的组合物 | |
| CN104146241B (zh) | 一种补益通便保健组合物及制备方法 | |
| CN106360664A (zh) | 一组止咳抗菌消炎清音治疗咽喉炎的橘红保健食品 | |
| KR101910013B1 (ko) | 한약재 추출물（ｓｏｃｇ）을 함유하는 통증의 개선, 예방 또는 치료용 조성물 | |
| CN103845616A (zh) | 一种消炎杀菌的药物组合物 | |
| CN106361805A (zh) | 一种具有清咽利喉功效的中药组合物及其制备方法和制剂 | |
| CN106615512A (zh) | 一种茄子蜂蜜润喉糖及其制备方法 | |
| CN105343840A (zh) | 一种中医内科治疗肺炎的中药 | |
| CN105343346A (zh) | 一种治疗外阴瘙痒的中药片剂及其制备方法 | |
| EA027691B1 (ru) | Средство для профилактики и лечения инфекционно-воспалительных заболеваний горла/глотки и ротовой полости на основе лекарственных растений | |
| CN104623615A (zh) | 一种治疗哮喘的药物 | |
| KR20170003153A (ko) | 천문동 추출물을 함유하는 호흡기 질환 예방 및 치료용 조성물 | |
| CN103961630A (zh) | 一种治疗胃气虚的中药组合物 | |
| CN113425767B (zh) | 一种治疗肺炎的中药组合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent of invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Huang Weian Inventor after: Meng Yi Inventor after: Teng Guang Inventor after: Li Jianqiang Inventor after: Wei Xiaoming Inventor after: Chen Lei Inventor before: Huang Weian Inventor before: Li Jianqiang Inventor before: Wei Xiaoming Inventor before: Chen Lei |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: HUANG WEIAN LI JIANQIANG WEI XIAOMING CHEN LEI TO: HUANG WEIAN MENG YI TENG GUANG LI JIANQIANG WEI XIAOMING CHEN LEI |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 537001 Yuyao Group Production Base, Renhou Town, Yuzhou District, Yulin City, Guangxi Zhuang Autonomous Region Patentee after: Guangxi Yulin Juan Health Products Co.,Ltd. Address before: 537001 Yuyao Group Production Base, Renhou Town, Yuzhou District, Yulin City, Guangxi Zhuang Autonomous Region Patentee before: GUANGXI YULIN PHARMACEUTICAL GROUP JUAN HEALTH-CARE PRODUCTS CO.,LTD. |