CN103583943A - 一种增加骨密度的保健品配方 - Google Patents
一种增加骨密度的保健品配方 Download PDFInfo
- Publication number
- CN103583943A CN103583943A CN201310470432.4A CN201310470432A CN103583943A CN 103583943 A CN103583943 A CN 103583943A CN 201310470432 A CN201310470432 A CN 201310470432A CN 103583943 A CN103583943 A CN 103583943A
- Authority
- CN
- China
- Prior art keywords
- gram
- healthcare product
- chondroitin sulfate
- health products
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 6
- 229910052500 inorganic mineral Inorganic materials 0.000 title abstract 2
- 239000011707 mineral Substances 0.000 title abstract 2
- 229920001287 Chondroitin sulfate Polymers 0.000 claims abstract description 17
- 229940059329 chondroitin sulfate Drugs 0.000 claims abstract description 17
- -1 chondroitin sulfate disaccharide Chemical class 0.000 claims abstract description 12
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims abstract description 6
- 241000287828 Gallus gallus Species 0.000 claims abstract description 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 10
- 230000037182 bone density Effects 0.000 claims description 9
- MTDHILKWIRSIHB-UHFFFAOYSA-N (5-azaniumyl-3,4,6-trihydroxyoxan-2-yl)methyl sulfate Chemical compound NC1C(O)OC(COS(O)(=O)=O)C(O)C1O MTDHILKWIRSIHB-UHFFFAOYSA-N 0.000 claims description 6
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 6
- 239000011575 calcium Substances 0.000 claims description 6
- 229910052791 calcium Inorganic materials 0.000 claims description 6
- CADZRPOVAQTAME-UHFFFAOYSA-L calcium;hydroxy phosphate Chemical compound [Ca+2].OOP([O-])([O-])=O CADZRPOVAQTAME-UHFFFAOYSA-L 0.000 claims description 6
- 229960002849 glucosamine sulfate Drugs 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Inorganic materials [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 5
- 239000011780 sodium chloride Substances 0.000 claims description 5
- 229930003316 Vitamin D Natural products 0.000 claims description 4
- 235000019166 vitamin D Nutrition 0.000 claims description 4
- 239000011710 vitamin D Substances 0.000 claims description 4
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 4
- 229940046008 vitamin d Drugs 0.000 claims description 4
- 241000272201 Columbiformes Species 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 210000001562 sternum Anatomy 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 4
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 abstract description 4
- 239000000654 additive Substances 0.000 abstract description 3
- 230000000996 additive effect Effects 0.000 abstract description 3
- 239000000126 substance Substances 0.000 abstract description 3
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 2
- 108010035532 Collagen Proteins 0.000 abstract 2
- 101800001386 Peptide II Proteins 0.000 abstract 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 abstract 2
- VDIQGOWLVYFDOU-UHFFFAOYSA-H [Ca+]O.[Ca+]O.[Ca+]O.[O-]P([O-])([O-])=O Chemical compound [Ca+]O.[Ca+]O.[Ca+]O.[O-]P([O-])([O-])=O VDIQGOWLVYFDOU-UHFFFAOYSA-H 0.000 abstract 2
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 abstract 2
- 229960004494 calcium gluconate Drugs 0.000 abstract 2
- 235000013927 calcium gluconate Nutrition 0.000 abstract 2
- 239000004227 calcium gluconate Substances 0.000 abstract 2
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 abstract 2
- 210000000845 cartilage Anatomy 0.000 abstract 2
- 229920001436 collagen Polymers 0.000 abstract 2
- 229960002442 glucosamine Drugs 0.000 abstract 2
- 229910052938 sodium sulfate Inorganic materials 0.000 abstract 2
- 235000011152 sodium sulphate Nutrition 0.000 abstract 2
- 235000005282 vitamin D3 Nutrition 0.000 abstract 2
- 239000011647 vitamin D3 Substances 0.000 abstract 2
- 229940021056 vitamin d3 Drugs 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 235000010755 mineral Nutrition 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 description 8
- 229920002683 Glycosaminoglycan Polymers 0.000 description 6
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 5
- 235000002639 sodium chloride Nutrition 0.000 description 5
- 102000016611 Proteoglycans Human genes 0.000 description 3
- 108010067787 Proteoglycans Proteins 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000006698 induction Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 150000002016 disaccharides Chemical group 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 210000002569 neuron Anatomy 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 208000018083 Bone metabolism disease Diseases 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 206010029350 Neurotoxicity Diseases 0.000 description 1
- 206010044221 Toxic encephalopathy Diseases 0.000 description 1
- LPQOADBMXVRBNX-UHFFFAOYSA-N ac1ldcw0 Chemical compound Cl.C1CN(C)CCN1C1=C(F)C=C2C(=O)C(C(O)=O)=CN3CCSC1=C32 LPQOADBMXVRBNX-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000007131 anti Alzheimer effect Effects 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- DZRJLJPPUJADOO-UHFFFAOYSA-N chaetomin Natural products CN1C(=O)C2(Cc3cn(C)c4ccccc34)SSC1(CO)C(=O)N2C56CC78SSC(CO)(N(C)C7=O)C(=O)N8C5Nc9ccccc69 DZRJLJPPUJADOO-UHFFFAOYSA-N 0.000 description 1
- DIUIQJFZKRAGBZ-UHFFFAOYSA-N chetoseminudin A Natural products O=C1C(SSS2)(CO)N(C)C(=O)C32CC2(N4C5=CC=CC=C5C(CC56C(N(C)C(CO)(SS5)C(=O)N6C)=O)=C4)C4=CC=CC=C4NC2N31 DIUIQJFZKRAGBZ-UHFFFAOYSA-N 0.000 description 1
- 230000009137 competitive binding Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 210000002744 extracellular matrix Anatomy 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 230000002887 neurotoxic effect Effects 0.000 description 1
- 231100000228 neurotoxicity Toxicity 0.000 description 1
- 230000007135 neurotoxicity Effects 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 230000001009 osteoporotic effect Effects 0.000 description 1
- 229920000447 polyanionic polymer Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 210000002243 primary neuron Anatomy 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
本发明提供了一种增加骨密度的保健品，该保健品由以下活性成分组成：硫酸软骨素二糖、Ⅱ型软骨胶原肽、氨基葡萄糖硫酸钠盐、葡萄糖酸钙、羟基磷酸钙和维生素D3。其中，每100克保健品中含有硫酸软骨素二糖25-30克、Ⅱ型软骨胶原肽20-25克、氨基葡萄糖硫酸钠盐10-15克、葡萄糖酸钙10-15克、羟基磷酸钙5-10克、维生素D33-5克。所述硫酸软骨素二糖主要由鸡球骨提取、分子量458.06，纯度在98%以上，灰分在0.5%以下。该保健品不含有任何添加剂和化学物质，无副作用，适合各阶段年龄层人群。
Description
技术领域
本发明涉及一种增加骨密度的保健品。
背景技术
骨质疏松现已成为中老年人的常见病和多发病，由于其本身没有特殊的临床表现，而且又是个缓慢的渐进过程，因而一直被大多数人所忽视，有报告称，中国大陆地区50岁以上的人群中有大约7000万人患有骨质疏松症，骨质疏松已经荣升为“城市慢性病”。为什么骨质疏松多发于老年人呢？骨科专家指出，主要是由于老年人内分泌比较紊乱、骨代谢失调，加上又缺少运动，所以容易导致骨质疏松，虽说骨质疏松常见于老年人，但也不能说是老年人的专属病，一些长期服用某类药物的人、哺乳期、妊娠期的女性也是骨质疏松的高危人群，也需要提高警惕。预防骨质疏松最有效的方法是增加骨密度。增加骨密度、有效治疗骨质疏松症已经成为人们广泛关注的重要课题。
发明内容
针对现有技术的上述缺陷和问题，本发明的目的是提供不含有任何添加剂和化学物质，无副作用，适合各阶段年龄层人群的增加骨密度的保健品。
基于上述目的，本发明提供如下技术方案：
一种增加骨密度的保健品，该保健品由以下活性成分组成：硫酸软骨素二糖、Ⅱ型软骨胶原肽、氨基葡萄糖硫酸钠盐、葡萄糖酸钙、羟基磷酸钙和维生素D3。
其中，每100克保健品中含有硫酸软骨素二糖25-30克、Ⅱ型软骨胶原肽20-25克、氨基葡萄糖硫酸钠盐10-15克、葡萄糖酸钙10-15克、羟基磷酸钙5-10克、维生素D33-5克。
所述硫酸软骨素二糖主要由鸡球骨提取、分子量458.06，纯度在98%以上，灰分在0.5%以下。
所述Ⅱ型软骨胶原肽由鸡胸骨提取，分子量在1KD以下。
本发明的有益效果是：本发明的保健品通过各种原料的共同作用，从而达到增加骨密度的作用。本发明所用原料为天然植物和动物提取物，不含有任何添加剂和化学物质，无副作用，适合各阶段年龄层人群。
具体实施方式
下面将结合本发明的实施例，对本发明的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
一种增加骨密度的保健品，该保健品由以下活性成分组成：硫酸软骨素二糖、Ⅱ型软骨胶原肽、氨基葡萄糖硫酸钠盐、葡萄糖酸钙、羟基磷酸钙和维生素D3。
其中，每100克保健品中含有硫酸软骨素二糖25-30克、Ⅱ型软骨胶原肽20-25克、氨基葡萄糖硫酸钠盐10-15克、葡萄糖酸钙10-15克、羟基磷酸钙5-10克、维生素D33-5克。
优选地技术方案中，硫酸软骨素二糖主要由鸡球骨提取、分子量458.06，纯度在98%以上，灰分在0.5%以下。
优选地技术方案中，Ⅱ型软骨胶原肽由鸡胸骨提取，分子量在1KD以下。
实施例1
每100克保健品中含有硫酸软骨素二糖30克、Ⅱ型软骨胶原肽25克、氨基葡萄糖硫酸钠盐15克、葡萄糖酸钙15克、羟基磷酸钙10克、维生素D35克
糖类及其衍生物抗AD的研究中发现GAGs（Glycosaminoglycan，糖胺聚糖）在AD发生过程中扮演着重要的角色。GAGs是由氨基己糖和糖醛酸的二糖单位重复连接而成的多聚阴离子高分子聚糖，作为蛋白聚糖（PGs）的支链分布在细胞外基质或动物组织细胞表面。
硫酸软骨素（CS）属于GAGs的一种，它具有促进大脑中神经元的生长的作用。CS能促进胎鼠大脑神经元的生长及诱导大部分神经増长突触的长度。CS能有效地降低Aβ诱导产生的神经细胞系和原代神经元的神经毒性作用，CS-A可以抑制和延迟Aβ形成，CS-B抑制Aβ1-42诱导的SH-SY5Y细胞凋亡，降低Aβ引起神经毒性从14d胎鼠端脑中提取得到的CS-D、CS-E具有潜在的促进成纤维细胞生长因子-2(FGF-2)相关的神经干细胞/前体细胞的增殖作用。CS硫酸化单糖及双糖可通过竞争性结合Aβ分子而抑制内源性GAGs、PGs的促纤丝形成作用，说明它们可能是内源性GAG诱导产生Aβ形成的抑制剂。
以上所述，仅为本发明的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，可轻易想到变化或替换，都应涵盖在本发明的保护范围之内。因此，本发明的保护范围应所述以权利要求的保护范围为准。
Claims (4)
1.一种增加骨密度的保健品，其特征在于，配方及重量比由硫酸软骨素二糖25-30克、Ⅱ型软骨胶原肽20-25克、氨基葡萄糖硫酸钠盐10-15克、葡萄糖酸钙10-15克、羟基磷酸钙5-10克、维生素D33-5克组成。
2.根据权利要求1所述的保健品，其特征在于，硫酸软骨素二糖主要由鸡球骨提取、分子量458.06，纯度在98%以上，灰分在0.5%以下。
3.根据权利要求1或2所述的保健品，其特征在于，Ⅱ型软骨胶原肽由鸡胸骨提取。
4.根据权利要求3所述的保健品，其特征在于，Ⅱ型软骨胶原肽的分子量在1KD以下。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310470432.4A CN103583943A (zh) | 2013-10-10 | 2013-10-10 | 一种增加骨密度的保健品配方 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310470432.4A CN103583943A (zh) | 2013-10-10 | 2013-10-10 | 一种增加骨密度的保健品配方 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103583943A true CN103583943A (zh) | 2014-02-19 |
Family
ID=50074430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310470432.4A Pending CN103583943A (zh) | 2013-10-10 | 2013-10-10 | 一种增加骨密度的保健品配方 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103583943A (zh) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104026239A (zh) * | 2014-06-26 | 2014-09-10 | 光明乳业股份有限公司 | 一种健骨牛奶及其制备方法 |
| CN104663836A (zh) * | 2015-03-21 | 2015-06-03 | 山东世纪春食品有限公司 | 一种新型钙奶饼干的生产方法 |
| CN108065405A (zh) * | 2017-12-15 | 2018-05-25 | 杭州得卜悠健康科技有限公司 | 用于提高骨密度的保健品 |
| CN108378374A (zh) * | 2018-02-08 | 2018-08-10 | 湖南易能生物医药有限公司 | 一种预防骨质疏松、促进骨健康的组合物 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101999662A (zh) * | 2010-06-17 | 2011-04-06 | 苟春虎 | 治疗骨质疏松胶囊 |
| CN102676613A (zh) * | 2012-05-22 | 2012-09-19 | 江南大学 | 一种硫酸软骨素二糖、四糖、六糖的制备方法 |
| CN102894372A (zh) * | 2012-11-05 | 2013-01-30 | 江苏江大源生态生物科技有限公司 | 一种增加骨密度的保健食品及其制备方法 |
| CN103060415A (zh) * | 2013-01-15 | 2013-04-24 | 青岛贝尔特生物科技有限公司 | 一种治疗风湿性关节炎的胶原蛋白制备方法 |
-
2013
- 2013-10-10 CN CN201310470432.4A patent/CN103583943A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101999662A (zh) * | 2010-06-17 | 2011-04-06 | 苟春虎 | 治疗骨质疏松胶囊 |
| CN102676613A (zh) * | 2012-05-22 | 2012-09-19 | 江南大学 | 一种硫酸软骨素二糖、四糖、六糖的制备方法 |
| CN102894372A (zh) * | 2012-11-05 | 2013-01-30 | 江苏江大源生态生物科技有限公司 | 一种增加骨密度的保健食品及其制备方法 |
| CN103060415A (zh) * | 2013-01-15 | 2013-04-24 | 青岛贝尔特生物科技有限公司 | 一种治疗风湿性关节炎的胶原蛋白制备方法 |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104026239A (zh) * | 2014-06-26 | 2014-09-10 | 光明乳业股份有限公司 | 一种健骨牛奶及其制备方法 |
| CN104663836A (zh) * | 2015-03-21 | 2015-06-03 | 山东世纪春食品有限公司 | 一种新型钙奶饼干的生产方法 |
| CN108065405A (zh) * | 2017-12-15 | 2018-05-25 | 杭州得卜悠健康科技有限公司 | 用于提高骨密度的保健品 |
| CN108378374A (zh) * | 2018-02-08 | 2018-08-10 | 湖南易能生物医药有限公司 | 一种预防骨质疏松、促进骨健康的组合物 |
| CN113713084A (zh) * | 2018-02-08 | 2021-11-30 | 湖南易能生物医药有限公司 | 一种组合物在制备治疗骨关节疼痛和中老年骨质疏松的药物中的应用 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101248882B (zh) | 一种具有促进骨骼和骨关节健康的营养食品 | |
| CN103583943A (zh) | 一种增加骨密度的保健品配方 | |
| Swiatkiewicz et al. | Prebiotic fructans and organic acids as feed additives improving mineral availability | |
| Świątkiewicz et al. | Dietary factors improving eggshell quality: An updated review with special emphasis on microelements and feed additives | |
| Kim et al. | Effects of age, vitamin D3, and fructooligosaccharides on bone growth and skeletal integrity of broiler chicks | |
| Yalçın et al. | Sepiolite as a feed supplement for broilers | |
| Upadhaya et al. | Importance of micronutrients in bone health of monogastric animals and techniques to improve the bioavailability of micronutrient supplements—A review | |
| Świątkiewicz et al. | Bones quality indices in laying hens fed diets with a high level of DDGS and supplemented with selected feed additives | |
| CN104758360B (zh) | 一种增加骨密度的组合物 | |
| CN108576394A (zh) | 老年宠物保健营养膏 | |
| JPWO2013136871A1 (ja) | 過硫酸化コンドロイチン組成物 | |
| CN103734508A (zh) | 一种提高蛋鸡免疫力的饲料 | |
| CN103330197A (zh) | 改善骨质疏松症的保健食品 | |
| CN103585305A (zh) | 一种辅助改善记忆的保健品配方 | |
| CN103082154A (zh) | 一种改善海参肉质的饲料 | |
| CN106689675A (zh) | 氨糖壮骨关节膏 | |
| CN102091324A (zh) | 养骨钙 | |
| Igbasan et al. | Growth response and carcass quality of broiler chickens fed on diets supplemented with dietary copper sources | |
| US20210161950A1 (en) | Veterinary Supplement for Effecting Bone and Cartilage | |
| CN103238839A (zh) | 用于保养关节的含胶原蛋白的食品组成物 | |
| CN105267949A (zh) | 退行性关节炎暨骨质疏松症的药物组方及其片剂制备方法 | |
| CN104256649A (zh) | 一种改善骨质疏松的食品 | |
| CA2708399A1 (en) | Composition for the treatment of osteoarthritis | |
| CN101077354A (zh) | 一种预防和治疗动物营养性腹泻的技术 | |
| CN104523804A (zh) | 一种增加骨密度的胶囊及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20140219 Assignee: Qingdao Belt Marine Technology Co., Ltd. Assignor: Better (Qingdao) Biological Technology Co., Ltd. Contract record no.: 2014370000175 Denomination of invention: Formula of healthcare product for increasing bone mineral density License type: Common License Record date: 20141208 |
|
| LICC | Enforcement, change and cancellation of record of contracts on the licence for exploitation of a patent or utility model | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140219 |