CN103520397A - 一种治疗毛发红糠疹的中药 - Google Patents
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Abstract
本发明涉及一种治疗毛发红糠疹的中药，由以下重量配比的药材制备而成：耳水苋12份、旱菜6份、盒果藤8份、红药子3份、黄杞4份、美人蕉5份、猬菊6份、乌蔹莓2份、舞草6份。临床实验证明，本发明能够安全有效治疗毛发红糠疹。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗毛发红糠疹的中药。
背景技术
毛发红糠疹是一种慢性炎症性皮肤病。表现为毛囊性坚硬的尖形小丘疹，中央有黑色角栓，常密集成片，表面伴糠状鳞屑。该病病因不明，症状轻，病程迁延；成人时期发病者可能与维甲醇结合蛋白缺陷、低血浆维生素A或甲状腺功能障碍等有关(获得性型)，发病较快，可发展为红皮病。最显著组织病理特征是表皮角化过度及毛囊性角质栓，栓内有一根毛发。毛囊口附近有点状角化不全，颗粒层稍增厚，棘层不规则肥厚，可有基底细胞液化变化。
对于毛发红糠疹目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
耳水苋【来源】 千屈菜科耳水苋Ammannia auriculata Willd.，以全草入药。【性味】 味甘；淡；性平。【归经】 归脾；膀胱经【功能主治】 健脾利湿；行气散瘀。主脾虚厌食；胸膈满闷；急慢性膀胱炎；妇女带下；跌打瘀肿作痛【用法用量】 内服：煎汤，12-24g，鲜品可用至30g；或泡酒。【注意】 孕妇禁服。
旱菜【来源】 伞形科旱芹属植物旱芹Apium graveolens L. var. dulce DC.，以茎或根入药。春夏秋均可采挖。洗净鲜用。【性味】 甘、微辛，凉。【功能主治】 降压利尿，凉血止血。用于头晕脑胀，高血压病，小便热涩不利，尿血，崩中带下。
盒果藤【来源】 旋花科盒果藤Operculina turpethum （L.） Manso，以根、全草入药。【性味】 甘；微苦；平。【功能主治】 利水；通便；舒筋。主水肿；大便秘结；久伤筋硬；不能伸缩。【用法用量】 内服：煎汤，6-10g。外用：适量，煎水洗。
红药子【来源】 为蓼科翼蓼属植物翼蓼Pteroxygonum giraldii Damm. et Diels，以块根入药。秋季采挖，除去茎叶及须根，洗净切片晒干。【功能主治】 酸、苦、涩，凉。【用法用量】 清热，解毒，止血，止痛。用于肠炎，痢疾，腰腿痛，便血，崩漏；外用治烧烫伤，疮疖，狂犬咬伤。【注意】 2～5钱；外用适量，捣烂敷患处，或研粉用油调涂患处。
黄杞【来源】 胡桃科黄杞Engelhardtia roxburghiana Wall.[E. chrysolepis Hance]，以树皮、叶入药。【性味】 树皮：微苦、辛，平。叶：微苦，凉。【功能主治】 树皮：行气，化湿，导滞。叶：清热止痛。脾胃湿滞，胸腹胀闷，湿热泄泻：树皮2～3钱，水煎服。疝气腹痛，感冒发热：叶4～5钱，水煎服。
美人蕉【来源】 美人蕉科美人蕉属植物美人蕉Canna indica L.，以根状茎和花入药。四季可采，鲜用或晒干。【性味】 甘、淡，凉。【功能主治】 清热利湿，安神降压。用于黄疸型急性传染性肝炎，神经功能症，高血压病，红崩，白带；外用治跌打损伤，疮疡肿毒。【用法用量】 1～2两，鲜根2～4两。外用鲜根适量，捣烂敷患处。
猬菊【来源】 菊科猬菊Takaikatzuchia lomonossowii （Trautv.） Kitag. et Kitam.，以全草入药。【性味】 甘，凉。【功能主治】 破血行瘀，凉血，止血。主治外伤，出血，吐血，鼻出血，子宫功能性出血；外用治疮毒痈肿。【用法用量】 5钱，配方用。外用鲜叶捣烂外敷。
乌蔹莓【来源】 本品为葡萄科植物乌蔹莓Cayratia japonica （Thunb.）Gagnep.，的全草。夏、秋采集，切段，晒干或鲜用。【性味】 苦、酸，寒。【功能主治】 解毒消肿，活血散瘀，利尿，止血。用于咽喉肿痛、目翳，咯血，血尿，痢疾；外用治痈肿，丹毒，腮腺炎，跌打损伤，毒蛇咬伤。【用法用量】 0.5～1两；外用适量，研末调敷或取汁涂患处。
舞草【来源】 豆科舞草Desmodium gyrans （L.）DC.，以全草入药。【性味】 微涩，平。【功能主治】 安神，镇静，祛瘀生新，活血消肿。主治神经衰弱，胎动不安：全草0.5～1两，水煎服。跌打肿痛，骨折：鲜全草捣烂，酒炒热外敷。小儿疳积：全草煅炭研粉，每次5～8分，温开水冲服，日服3次。风湿腰痛：全草0.5～1两，水煎服，并取鲜叶捣烂，酒炒外敷。此外，尚可治精神病，狂犬咬伤。
发明内容
本发明旨在提供一种治疗毛发红糠疹的中药，通过选择合适的药材及其配比，达到安全有效治愈毛发红糠疹的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗毛发红糠疹的中药，其特征在于，由以下重量配比的药材制备而成：耳水苋12份、旱菜6份、盒果藤8份、红药子3份、黄杞4份、美人蕉5份、猬菊6份、乌蔹莓2份、舞草6份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年8月-2012年12月间共收集120例毛发红糠疹的门诊患者，年龄19-65岁，病程3个月-3年。随机分为：治疗组100例，空白组20例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程15天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程15天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 不良反应例 | 总有效率(%) |
| 治疗组 | 100 | 36 | 44 | 20 | 0 | 80% |
| 空白组 | 20 | 0 | 3 | 17 | 0 | 15% |
可见，本发明制得的药物能够安全有效治疗毛发红糠疹。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：耳水苋12克、旱菜6克、盒果藤8克、红药子3克、黄杞4克、美人蕉5克、猬菊6克、乌蔹莓2克、舞草6克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗毛发红糠疹。口服，每日分早晚两次服用。
具体实施例2
称取：耳水苋12克、旱菜6克、盒果藤8克、红药子3克、黄杞4克、美人蕉5克、猬菊6克、乌蔹莓2克、舞草6克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗毛发红糠疹。口服，每日分早晚两次服用。
具体实施例3
称取：耳水苋12克、旱菜6克、盒果藤8克、红药子3克、黄杞4克、美人蕉5克、猬菊6克、乌蔹莓2克、舞草6克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗毛发红糠疹。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗毛发红糠疹的中药，其特征在于，由以下重量配比的药材制备而成：耳水苋12份、旱菜6份、盒果藤8份、红药子3份、黄杞4份、美人蕉5份、猬菊6份、乌蔹莓2份、舞草6份。
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