CN102657725B - 一种治疗便秘的中药 - Google Patents
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Abstract
本发明涉及一种治疗便秘的中药，其特征在于，它是由以下重量份的药材组成：火麻仁30-50份，陈皮30-50份，熟大黄30-50份，厚朴10-20份，枳实10-20份，柏子仁30-50份、桃仁30-50份，槐花10-20份、地榆10-20份，滑石粉10-20份。实验证明，本发明能够安全有效治疗便秘。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗便秘的中药。
背景技术
便秘是临床常见的复杂症状，主要是指排便次数减少、粪便量减少、粪便干结、排便费力等，表现为一般每2~3天或更长时间排便一次。目前的治疗药物主要是泻药，治标不治本，且常用有依赖性和副作用。因此研究开发一种安全有效治疗便秘的中药非常有实用价值。
本发明中药所涉及药材的研究现状如下：
火麻仁：【来源】本品为桑科植物大麻Cannabis sativa L.的干燥成熟果实。【功能主治】润肠通便。用于血虚津亏，肠燥便秘。
陈皮：【来源】本品为芸香科植物橘Citrus reticulata Blanco 及其栽培变种的干燥成熟果皮。【功能主治】理气健脾，燥湿化痰。用于胸脘胀满，食少吐泻，咳嗽痰多。
熟大黄：【来源】本品为蓼科植物掌叶大黄Rheum palmatum L。、 唐古特大黄Rheum tanguticum Maxim。 ex Balf。或药用大黄Rheum officinale Baill。的干燥根及根茎。【功能主治】泻热通肠，凉血解毒，逐瘀通经。用于实热便秘，积滞腹痛，泻痢不爽，湿热黄疸，血热吐衄，目赤，咽肿，肠痈腹痛，痈肿疔疮，瘀血经闭，跌打损伤，外治水火烫伤；上消化道出血。酒大黄善清上焦血分热毒。用于目赤咽肿，齿龈肿痛。熟大黄泻下力缓，泻火解毒。用于火毒疮疡。大黄炭凉血化瘀止血。用于血热有瘀出血症。
厚朴：【来源】本品为木兰科植物厚朴Magnolia officinalis Rehd. et Wils.或凹叶厚朴Magnolia officinalis Rehd. et Wils. var. biloba Rehd. et Wils.的干燥干皮、根皮及枝皮。【功能主治】燥湿消痰，下气除满。用于湿滞伤中，脘痞吐泻，食积气滞，腹胀便秘，痰饮喘咳。
枳实：【来源】本品为芸香科植物酸橙Citrus aurantium L. 及其栽培变种或甜橙Citrus sinensis Osbeck 的干燥幼果。【功能主治】破气消积，化痰散痞。用于积滞内停，痞满胀痛，泻痢后重，大便不通，痰滞气阻胸痹，结胸；胃下垂，脱肛，子宫脱垂。
柏子仁：【来源】本品为柏科植物侧柏Platycladus orientalis （L.） Franco的干燥成熟种仁。【功能主治】养心安神，润肠通便。治惊悸，失眠，遗精，盗汗，便秘。
桃仁：【来源】本品为蔷薇科植物桃Prunus persica （L.） Batsch 或山桃 Prunus davidiana （Carr.）Franch.的干燥成熟种子。【功能主治】活血祛瘀，润肠通便。用于经闭，痛经，癓瘕痞块，跌扑损伤，肠燥便秘。
槐花：【来源】本品为豆科植物槐Sophora japonica L.的干燥花及花蕾。【功能主治】凉血止血，清肝泻火。用于便血，痔血，血痢，崩漏，吐血，衄血，肝热目赤，头痛眩晕。
地榆：本品为蔷薇科植物地榆Sanguisorba officinalis L.或长叶地榆Sanguisorba off icinalis L.var.longifolia （Bert.） Yu et Li 的干燥根。【功能主治】凉血止血，解毒敛疮。用于便血，痔血，血痢，崩漏，水火烫伤，痈肿疮毒。
滑石粉：【来源】本品系滑石经精选净化、粉碎、干燥制成。【功能主治】利尿通淋，清热解暑，祛湿敛疮。用于热淋，石淋，尿热涩痛，暑湿烦渴，湿热水泻；外治湿疹，湿疮，痱子。
发明内容
本发明旨在提供一种治疗便秘的中药，通过选择合适的药材及其配比，达到安全有效治愈便秘的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗便秘的中药，其特征在于，它是由以下重量份的药材组成：火麻仁30-50份，陈皮30-50份，熟大黄30-50份，厚朴10-20份，枳实10-20份，柏子仁30-50份、桃仁30-50份，槐花10-20份、地榆10-20份，滑石粉10-20份。
其中优选：火麻仁40份，陈皮40份，熟大黄40份，厚朴15份，枳实15份，柏子仁40份、桃仁40份，槐花15份、地榆15份，滑石粉15份。
本发明具体使用方法：正常成年患者每日需服用使用“火麻仁30-50克，陈皮30-50份，熟大黄30-50克，厚朴10-20克，枳实10-20克，柏子仁30-50克，桃仁30-50克，槐花10-20克、地榆10-20克，滑石粉10-20克”，按照常规制药工艺，制得的成药。
下面结合中医理论说明本发明的有益效果：
发明人在实践过程中发现，便秘是由于心火燥热，火邪留滞血中，耗散真阴，津液亏少，下焦集痞造成的。故治疗应以化积毒，破气消积散痞为主。本发明运用火麻仁、柏子仁、桃仁首润肠通便；陈皮、厚朴、枳实、滑石粉健脾燥湿、破气化痰；熟大黄、槐花、地榆清热泻火解毒。诸药合用，消积泻热通肠，通下焦而导，从而有效地治疗便秘。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2009年6月-2012年1月间共收集75例便秘的门诊患者，其中男40例，女35例，年龄12-65岁，病程2天-3年。随机分为：治疗组50例，对照组25例。两组性别、年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗方法
对照外用开塞露，按照说明书使用。疗程1周。
治疗组口服本发明优选实施方式按照具体实施例1制得的胶囊，每日分2次服用。疗程1周。
2.2观察项目：对大便次数，干结状况等症状进行观察。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失。好转：临床症状减轻。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 不良反应例 | 总有效率(%) |
| 治疗组 | 50 | 42 | 6 | 2 | 0（0%） | 96% |
| 对照组 | 25 | 5 | 18 | 2 | 0（0%） | 92% |
可见，本发明优选实施方式制得的药物能够安全有效治疗便秘。
根据上述临床实验数据，结合本发明治疗便秘的中医学机理分析和本领域公知常识，本领域技术人员容易推知，运用本发明中的药材，在最佳重量份附近取值，至少在“火麻仁30-50份，陈皮30-50份，熟大黄30-50份，厚朴10-20份，枳实10-20份，柏子仁30-50份、桃仁30-50份，槐花10-20份、地榆10-20份，滑石粉10-20份”的范围内，可以取得与本发明优选实施方式制得的药物类似的技术效果。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取火麻仁40克，陈皮40克，熟大黄40克，厚朴15克，枳实15克，柏子仁40克、桃仁40克，槐花15克、地榆15克；加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，加入滑石粉15克，装入胶囊壳，即得符合正常成人一天用量的胶囊剂。
用于治疗便秘。口服，每日分早晚两次服用。
具体实施例2
称取火麻仁30克，陈皮30克，熟大黄30克，厚朴10克，枳实10克，柏子仁30克份、桃仁克，槐花克、地榆1克；加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，加入滑石粉10克，包装，即得符合正常成人一天用量的散剂。
用于治疗便秘。口服，每日分早中晚三次服用。
具体实施例3
称取火麻仁50克，陈皮50克，熟大黄50克，厚朴20克，枳实20克，柏子仁50克、桃仁50克，槐花20克、地榆20克；加6倍量水，煎煮3次，每次煎煮1小时，合并煎煮液，浓缩，加入滑石粉20克，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人一天用量的颗粒剂。
用于治疗便秘。口服，每日分早中晚三次服用。
Claims (1)
1.一种治疗便秘的中药，其特征在于，它是由以下重量份的药材组成：火麻仁40份，陈皮40份，熟大黄40份，厚朴15份，枳实15份，柏子仁40份、桃仁40份，槐花15份、地榆15份，滑石粉15份。
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| CN105902720A (zh) * | 2016-04-17 | 2016-08-31 | 河南中医学院第附属医院 | 一种治疗小儿便秘的枳朴五仁通便栓及其制备方法 |
| CN105902932A (zh) * | 2016-05-24 | 2016-08-31 | 王桂英 | 一种治疗便秘的中药汤剂 |
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| CN1879739A (zh) * | 2006-05-15 | 2006-12-20 | 孙书杰 | 治疗便秘的中药制剂 |
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