CN103520107A - 一种阴道填塞泡沫剂 - Google Patents
一种阴道填塞泡沫剂 Download PDFInfo
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- CN103520107A CN103520107A CN201310470909.9A CN201310470909A CN103520107A CN 103520107 A CN103520107 A CN 103520107A CN 201310470909 A CN201310470909 A CN 201310470909A CN 103520107 A CN103520107 A CN 103520107A
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- parts
- vaginal
- treatment
- vaginitis
- vaginal plugging
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- 229910052709 silver Inorganic materials 0.000 claims abstract description 8
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- 229910000166 zirconium phosphate Inorganic materials 0.000 claims abstract description 8
- LEHFSLREWWMLPU-UHFFFAOYSA-B zirconium(4+);tetraphosphate Chemical compound [Zr+4].[Zr+4].[Zr+4].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O LEHFSLREWWMLPU-UHFFFAOYSA-B 0.000 claims abstract description 8
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- 108010067306 Fibronectins Proteins 0.000 claims abstract description 5
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- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 claims abstract description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 4
- ZSBXGIUJOOQZMP-UHFFFAOYSA-N Isomatrine Natural products C1CCC2CN3C(=O)CCCC3C3C2N1CCC3 ZSBXGIUJOOQZMP-UHFFFAOYSA-N 0.000 claims abstract description 4
- ZSBXGIUJOOQZMP-JLNYLFASSA-N Matrine Chemical compound C1CC[C@H]2CN3C(=O)CCC[C@@H]3[C@@H]3[C@H]2N1CCC3 ZSBXGIUJOOQZMP-JLNYLFASSA-N 0.000 claims abstract description 4
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 4
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229960001631 carbomer Drugs 0.000 claims abstract description 4
- YLTGFGDODHXMFB-UHFFFAOYSA-N isoacetovanillon Natural products COC1=CC=C(C(C)=O)C=C1O YLTGFGDODHXMFB-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229930014456 matrine Natural products 0.000 claims abstract description 4
- MLIBGOFSXXWRIY-UHFFFAOYSA-N paeonol Natural products COC1=CC=C(O)C(C(C)=O)=C1 MLIBGOFSXXWRIY-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000008213 purified water Substances 0.000 claims abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 239000006260 foam Substances 0.000 claims description 25
- 206010046914 Vaginal infection Diseases 0.000 claims description 15
- 238000003756 stirring Methods 0.000 claims description 14
- 201000008100 Vaginitis Diseases 0.000 claims description 10
- 208000004926 Bacterial Vaginosis Diseases 0.000 claims description 9
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 8
- 206010008323 cervicitis Diseases 0.000 claims description 8
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- 210000001215 vagina Anatomy 0.000 description 10
- 239000000047 product Substances 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 6
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- 230000003628 erosive effect Effects 0.000 description 4
- 208000003251 Pruritus Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 108091007643 Phosphate carriers Proteins 0.000 description 2
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 235000013527 bean curd Nutrition 0.000 description 2
- 210000003756 cervix mucus Anatomy 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 2
- 239000002893 slag Substances 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000000829 suppository Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 229910052725 zinc Inorganic materials 0.000 description 2
- 239000011701 zinc Substances 0.000 description 2
- ONDPHDOFVYQSGI-UHFFFAOYSA-N zinc nitrate Chemical compound [Zn+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ONDPHDOFVYQSGI-UHFFFAOYSA-N 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 1
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- 208000008350 Pruritus Vulvae Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010056530 Vulvovaginal pruritus Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 238000001354 calcination Methods 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
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- 239000003814 drug Substances 0.000 description 1
- 239000007938 effervescent tablet Substances 0.000 description 1
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethanethiol Chemical compound CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 230000003821 menstrual periods Effects 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
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- 239000013558 reference substance Substances 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 210000004994 reproductive system Anatomy 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 229910001961 silver nitrate Inorganic materials 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201310470909.9A CN103520107B (zh) | 2013-10-11 | 2013-10-11 | 一种阴道填塞泡沫剂 |
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CN201310470909.9A CN103520107B (zh) | 2013-10-11 | 2013-10-11 | 一种阴道填塞泡沫剂 |
Publications (2)
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CN103520107A true CN103520107A (zh) | 2014-01-22 |
CN103520107B CN103520107B (zh) | 2016-08-17 |
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CN201310470909.9A Expired - Fee Related CN103520107B (zh) | 2013-10-11 | 2013-10-11 | 一种阴道填塞泡沫剂 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105749277A (zh) * | 2016-03-10 | 2016-07-13 | 陕西瑞凯生物科技有限公司 | 一种卵黄生物蛋白泡沫填塞剂及其制备方法 |
US9884049B2 (en) | 2014-07-14 | 2018-02-06 | Orion Biotechnology Canada Ltd. | Microbicidal composition comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1762488A (zh) * | 2005-10-08 | 2006-04-26 | 张怡 | 人细胞纤连蛋白的外用药物组合物及其制备方法 |
CN101062055A (zh) * | 2007-06-06 | 2007-10-31 | 崔彬 | 一种缓释型纳米银抗菌凝胶剂及其制备方法与应用 |
CN102872159A (zh) * | 2012-09-29 | 2013-01-16 | 广东同德药业有限公司 | 一种治疗阴道细菌性炎症的纳米银壳聚糖凝胶泡沫制剂及其制备方法 |
-
2013
- 2013-10-11 CN CN201310470909.9A patent/CN103520107B/zh not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1762488A (zh) * | 2005-10-08 | 2006-04-26 | 张怡 | 人细胞纤连蛋白的外用药物组合物及其制备方法 |
CN101062055A (zh) * | 2007-06-06 | 2007-10-31 | 崔彬 | 一种缓释型纳米银抗菌凝胶剂及其制备方法与应用 |
CN102872159A (zh) * | 2012-09-29 | 2013-01-16 | 广东同德药业有限公司 | 一种治疗阴道细菌性炎症的纳米银壳聚糖凝胶泡沫制剂及其制备方法 |
Non-Patent Citations (5)
Title |
---|
南京亚方药业有限公司: "医用抗菌凝胶喷剂(商品名:阴道填塞泡沫剂)", 《国家食品药品监督管理总局数据库》, 15 March 2013 (2013-03-15) * |
张经理: "妇科 宫颈炎 宫颈糜烂 助尔银离子妇用凝胶", 《医药信息网》, 7 January 2013 (2013-01-07), pages 1 - 2 * |
曲宏晶等: "纤维结合蛋白软膏治疗宫颈糜烂双盲对照观察", 《中国妇幼保健》, vol. 24, no. 10, 31 December 2009 (2009-12-31), pages 1434 - 1435 * |
李强等: "《新编常用中药有效成分手册》", 31 January 2008, article "丹皮酚", pages: 102 - 104-105 * |
陈永桑等: "《国内外药品名称辞典》", 31 December 1991, article "苦参碱", pages: 113 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9884049B2 (en) | 2014-07-14 | 2018-02-06 | Orion Biotechnology Canada Ltd. | Microbicidal composition comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof |
CN105749277A (zh) * | 2016-03-10 | 2016-07-13 | 陕西瑞凯生物科技有限公司 | 一种卵黄生物蛋白泡沫填塞剂及其制备方法 |
Also Published As
Publication number | Publication date |
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CN103520107B (zh) | 2016-08-17 |
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Effective date of registration: 20160408 Address after: 211505 D7 building, Zhongshan Science Park, Liuhe District, Jiangsu, Nanjing Applicant after: NANJING YAFANG PHARMACEUTICAL Co.,Ltd. Address before: 222200, No. 3-3, salt transportation road, Yi Town, Guanyun County, Lianyungang, Jiangsu Applicant before: Xu Kezhi |
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Addressee: NANJING YAFANG PHARMACEUTICAL Co.,Ltd. Person in charge of patentsThe principal of patent Document name: payment instructions |
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Addressee: NANJING YAFANG PHARMACEUTICAL Co.,Ltd. Person in charge of patentsThe principal of patent Document name: Notice of Termination of Patent Rights |
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Granted publication date: 20160817 |