CN103494959A - Drug for treating high blood pressure - Google Patents
Drug for treating high blood pressure Download PDFInfo
- Publication number
- CN103494959A CN103494959A CN201310480608.4A CN201310480608A CN103494959A CN 103494959 A CN103494959 A CN 103494959A CN 201310480608 A CN201310480608 A CN 201310480608A CN 103494959 A CN103494959 A CN 103494959A
- Authority
- CN
- China
- Prior art keywords
- blood pressure
- radix clerodendri
- folium
- dry
- leaf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a drug for treating high blood pressure and relates to Chinese traditional patent medicine. The drug is prepared from, according to a formula, by weight, 1-2 parts of smelly jasmine leaves, 1-2 parts of persimmon leaves and 10-20 parts of black Chinese olive leaves. The dried smelly jasmine leaves, the dried persimmon leaves and the dried black Chinese olive leaves are blended and smashed to be prepared into an agent, or capsules, or packed into packages through tea-brewing paper. The drug for treating the high blood pressure has the advantages of good curative effect with a total effective rate of treating the high blood pressure reaching to 97.5% and an efficiency show rate reaching to 86.9%, rapidness in effect and immediate effect for symptoms of brain swelling and fatigue, safeness and no toxic side effects for normal use, and easiness in obtaining raw materials and preparing and applying.
Description
Technical field
The present invention relates to Chinese patent medicine, espespecially a kind ofly treat hypertensive medicine.
Background technology
Hypertension is to take under quiescent condition systolic arterial pressure and diastolic pressure to raise and exceed the disease that be symptom normal range, is a kind of systemic disease that is attended by the functional or organic change of heart, blood vessel, brain and kidney and other organs.
The Chinese medicine of China is the treasure-house of an extensive knowledge and profound scholarship, is containing huge usefulness, and Chinese medicine or Chinese patent drugs for treatment hypertension are no exception.
Chinese patent discloses health-care blood pressure lowering food (publication number CN 102028219A), and its formula is 1～5 part of (by weight) Folium Crataegi, 0.1～2 part of Folium clausenae lansii, 0.1～2 part, Fructus Citri tangerinae leaf, 5～20 parts of Folium Canarii Pimelae.This health-care blood pressure lowering food has been started the beginning for blood pressure lowering by Folium Canarii Pimelae, and the combination of their specific deal has the effect of blood pressure lowering.But its formula requires further improvement, curative effect needs further to improve, and using method needs more can meet patient's selection.
Summary of the invention
The present invention is intended to enrich the kind of blood pressure lowering Chinese patent medicine, improves the effect of blood pressure lowering Chinese patent medicine, and a kind of hypertensive medicine for the treatment of is provided.Its formula material is easy to get, and makes easily and goes, and can be made into multiple dosage form, and curative effect is outstanding.
In order to realize above-mentioned task, the present invention is a kind of, and to treat the technical scheme of hypertensive medicine as follows.
A kind ofly treat hypertensive medicine, formula by weight is, 1～2 part, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 1～2 part of Folium Kaki, 10～20 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
The leaf that described Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf in we is Radix clerodendri fragrantis (Radix Clerodendri Philippini), Radix clerodendri fragrantis (Radix Clerodendri Philippini) belongs to semishrub plant.Referring to Guangzhou army rear service section " the 374th page of Chinese herbal medicine handbook commonly used (People's Health Publisher, publish in March, 1970), the main expelling wind and activating blood circulation that rises in we, detumescence, the effect of blood pressure lowering.
The leaf that described Folium Kaki in we is the fruit tree Fructus Kaki.Referring to the 154th page of Liu Jizhu chief editor " Chinese herbal medicine identification and application " (middle volume) (the Guangdong People's Press, in December, 2010 is published), in we main rise sending down the abnormal ascending QI only oh, arrhythmia and sedation.
Modern pharmacology research shows, Folium Kaki has pharmacological action widely, comprise the multiple efficacies (" chemical composition of Folium Kaki, pharmacological action, clinical practice and exploitation " food and fermentation industries 2005 VOL 31 NO7, Lin Jiaofen etc.) such as vasodilation (vessel softening), blood fat-reducing blood pressure-decreasing, hemostasis.
The leaf that described Folium Canarii Pimelae in we is the Fructus Canarii Pimelae fruit tree.Referring to the 122nd page of Wang Yusheng, Cai Yuewen chief editor " southern medicinal plants illustrated handbook " (publishing house of University Of Shantou, in JIUYUE, 2004 is published).Mainly in we play hemostasis, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, reduce phlegm, the effect of diuretic.
Modern study experiment showed, the Folium Canarii Pimelae water extract to stress Hypertensive Rats have remarkable hypotensive effect (" the Folium Canarii Pimelae water extract is to stress Hypertensive Rats there being the research of remarkable hypotensive effect ", Tianjin medical science, 2007,35(8): 587～590).In " the Folium Canarii Pimelae water extract is to Isolated Rat blood vessel direct effect experimentation " (Guangdong medical science, November the 29th in 2008 volume o. 11th), point out: 1. Folium Canarii Pimelae has vascular smooth muscle is had to the diastole effect, and certain dose relation is arranged; 2. high potassium is brought out to the tension force that vascular ring shrinks and there is booster action.
Hypertensive is a very complicated process, relate to many aspects such as nerve, body fluid, inner skin cell function, genetic defect, be summed up three approach and cause elevation of the blood pressure: 1. peripheral blood vessel increases (resistance vessel contraction)---and cause and take the diastolic pressure rising as main hypertension; 2. cardiac output increases (increased heart rate, myocardial contraction strengthens)---cause that it is main hypertension that systolic pressure raises; 3. the increase of blood vessel amount or blood viscosity increase.
The traditional Chinese medical science thinks that hypertension is depressed emotion, the troubled thoughts of being enraged, so that depression of liver-QI, fire-transformation impairment of YIN; Or intemperance of taking food, hungry full inappropriate, taste are injured, the turbid interior life of expectorant; Or old asthenia, Liver and kidney imbalance of YIN and YANG etc.The basic principle of Traditional Chinese Medical on Treating Hypertension: the conditioning viscera function, recover equilibrium between yin and yang.In above-mentioned three kinds of leaves, the Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf plays expelling wind and activating blood circulation, detumescence, blood pressure lowering.Folium Kaki plays blood fat reducing, reduces blood viscosity, reduces hypertensive effect.Folium Canarii Pimelae plays significant hypotensive activity, the heating that simultaneously cures cold, cough due to lung-heat, reduces phlegm.These three kinds of cool collocation of leaf temperature, hot or cold and cool body constitution is all suitable.We from the promoting flow of QI and blood that reduces phlegm, remove unnecessary blood fat and cholesterol is started with, and take that to reduce blood viscosity be handgrip, the effective ingredient of three kinds of leaves is coordinated mutually, complements each other, and with its specific composition combination and specific deal combination thereof, realizes reducing hypertensive effect.
The present invention has outstanding feature: the one, and good effect, treatment high blood pressure disease total effective rate reaches 97.5%, and obvious effective rate reaches 86.9%; The 2nd, instant effect, especially, to dizzy or tired symptom, can take effect at once; The 3rd, safety, positive common medicine, have no side effect.The 4th, raw material is easy to get, and makes easily and goes.
The specific embodiment
Below, introduce the specific embodiment of the present invention.
One, embodiment
Embodiment 1
A kind ofly treat hypertensive medicine, formula by weight is, 1 part, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 1 part of Folium Kaki, 10 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
Embodiment 2
A kind ofly treat hypertensive medicine, formula by weight is, 1 part, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 1 part of Folium Kaki, 15 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
Embodiment 3
A kind ofly treat hypertensive medicine, formula by weight is, 1 part, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 1 part of Folium Kaki, 20 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
Embodiment 4
A kind ofly treat hypertensive medicine, formula by weight is, 2 parts, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 2 parts of Folium Kaki, 15 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
Two, clinical observation test
?(1), clinical treatment
Case is selected: since 2012, selected 269 routine hyperpietics to carry out the clinical observation test, the diagnostic criteria of higher medical institution teaching material of all take is foundation, is divided into three case groups:
1, take tablet case group, 73 examples;
2, take capsule case group, 81 examples;
3, take group in the mode of making tea, 115 examples.
(2), using method
1, take tablet case group, the tablet of oral medicine, three times on the one, each 5 grams, then look change of illness state and reduce in right amount.From every day three times, after blood pressure is normal, decrement is to every twice-daily, then decrement is to once a day, to the next day maintenance dose to keep blood pressure normal.
2, take capsule case group, the capsule of oral medicine, three times on the one, each 5 grams, then look change of illness state and reduce in right amount.From every day three times, after blood pressure is normal, decrement is to every twice-daily, then decrement is to once a day, to the next day maintenance dose to keep blood pressure normal.
The mode of 3, making tea with the boiled water that boils is taken group, with this medicated bag, makes tea oral, and three times on the one, boil boiled water bubble of each 1 parcel (5 gram), connect and rush 4～5 bubbles, and every bubble is washed 150 milliliters of left and right of water open, leaches tea and drinks, then look change of illness state and reduce in right amount.From every day three times, after blood pressure is normal, decrement is to every twice-daily, then decrement is to once a day, to the next day maintenance dose to keep blood pressure normal.
4, observe and change, before taking medicine and during treatment, check blood pressure, body temperature, pulse and heartbeat function, during treatment, check once every day.
5, points for attention:
1) if the hypertension caused because of heart, nephropathy, this disease of Ying Xianzhi coordinates blood pressure lowering again.
2) most hyperpietics are relevant with Bad Eating Habit, answer in daily life light diet, the few fat of the few sugar of few salt, few smoking is drunk and is spilt less, polyphagia fruit is dredged dish, does not eat pluck, fat and decocts, explodes, fires food, and Broiled Dish wherein is as roasted chicken duck goose etc.
3) contraindication in pregnancy.
4) take after the meal, avoid untoward reaction.
(3), observation of curative effect
1, criterion of therapeutical effect (three groups of cases are carried out a standard):
Produce effects---the second day of taking medicine first, dizzy or tired symptom obviously alleviates, the 15th day normal of taking blood pressure.
Effectively---the second day of taking medicine first, dizzy or tired sx↓, the 15th staggering amount blood pressure drops.
Invalid---clinical symptoms [by inquiry with analyze, by points for attention requirements ring mouth, is still eaten pluck, fat and decocts, explodes, fires food etc. relevant with the patient] without improving.
2, observed result
(4), toxic and side effects test
The mode of making tea with this medicine is taken, and white mice is carried out to toxicity test.Get after cool the freezing of tea (approximately 750 milliliters) of 15 grams with the boiled water bubble 5 times of boiling 10 white mice of throwing something and feeding every day, within continuous 30 days, observe, white mice is without abnormal response, none death.
(5), model case introduction
Zhong Tianzhao, 48 years old now, rose in February, 2012, has a hunch fatigue, nose heave, blurred vision, sleep before 9 every night, perpendicular day 6 a lot of beds, always have the inadequate sensation of sleeping.Through taking blood pressure, be 200/112mmHg, be serious hypertension.The mode of making tea with this medicine is taken, and morning, noon and afternoon every day, after the meal respectively once each parcel (5 ɡ) boiled water that boils brewed, and connects and rushes 4～5 bubbles, and every bubble is washed 150 milliliters of left and right of water open, leaches tea and drinks.The original symptom of second day of drinking this medicated tea obviously alleviates, the 5th day 165/92 mmHg that takes blood pressure, the 10th day 152/85 mmHg that takes blood pressure, the 15th day 142/80 mmHg that takes blood pressure, normal blood pressure.Within the 16th day, rising to the 36th day was second course for the treatment of, and sooner or later after the meal respectively once each parcel (5 ɡ), took blood pressure, remained between 138～140/77～80 mmHg in every 5 days every day.The 3rd course for the treatment of is since the 37th day to half a year, once a day, and each parcel (5 ɡ).Change again every other day once each parcel (5 ɡ) after half a year into.Adhere to having drunk more than a year, blood pressure remains on normal range.
Liu Shiguang, 70 years old now, before 2 years, because of the hypertension apoplexy, be hospitalized for treatment, taking Western medicine after leaving hospital has half a year, blood pressure or higher, blood pressure is 175/106mmHg.Take morning, noon and afternoon every day early stage after the meal respectively once in the mode of making tea of this medicine, each parcel (5 ɡ) boiled water that boils brews to lightly seasoned, leaches tea and drinks, and within the 5th day, taking blood pressure is 163/98 mmHg, the 10th day
amountblood pressure is 14,2/8 6 mmHg, and normal changes every day into sooner or later after the meal respectively once after 10 days, and each parcel (5 ɡ), took blood pressure and substantially remain between 140～142/78～82 mmHg every 5 days, belongs to the higher normal arterial pressure of old people.Drunk again more than 20 day, changed into afterwards once a day, drunk half a year, changed into after half a year often every other day once, had more than a year so far, blood pressure is all in range of normal value.
Pan Mengying, 65 years old now, because hypertension often has headache and fatigue symptom, often to the community clinic garter, to get it filled the year before, blood pressure still is difficult to recover normal value, heavy when light during symptom.Take front blood pressure 170/102 mmHg of this medicine and headache, fatigue symptom are arranged.Easily how to take for the first time this Drug Capsule after one hour, original symptom obviously alleviates.Get this Drug Capsule and overcome use by every day 3 times, each 5, do not beat garter and do not eat other depressor, after 15 days, blood pressure recovers normal value.Thereafter, medication is decrement progressively, and existing maintenance dose is (5 gram) every other day once.Blood pressure is normal over one year: 139～140/79～81 mmHg.
(6), untoward reaction
While taking in the mode of making tea of this medicine, if drink on an empty stomach, there are one or two people to think that saliva is light, the sensation of regurgitation arranged, therefore drink and be advisable after the meal.
(7), brief summary
1, a kind of clinical observation for the treatment of hypertensive medicine of releasing from this 269 routine hyperpietic being taken to the present invention, this medicine has therapeutical effect to high blood pressure disease, and total effective rate reaches 97.5%, and wherein obvious effective rate reaches 86.9%.
2, in clinical use, in patient's body temperature, blood pressure measurement and cardiac auscultation, do not find obvious adverse reaction, this medicine no side effects can be described.
Claims (5)
1. the hypertensive medicine for the treatment of, is characterized in that, formula by weight is: 1～2 part, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 1～2 part of Folium Kaki, 10～20 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
2. a kind of hypertensive medicine for the treatment of according to claim 1, is characterized in that, formula by weight is: 1 part, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 1 part of Folium Kaki, 10 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
3. a kind of hypertensive medicine for the treatment of according to claim 1, is characterized in that, formula by weight is: 1 part, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 1 part of Folium Kaki, 15 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
4. a kind of hypertensive medicine for the treatment of according to claim 1, is characterized in that, formula by weight is: 2 parts, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 2 parts of Folium Kaki, 15 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
5. according to claim 1 hypertensive medicine for the treatment of, it is characterized in that, formula by weight is: 1 part, Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf, 1 part of Folium Kaki, 20 parts of Folium Canarii Pimelae; By the dry Radix clerodendri fragrantis (Radix Clerodendri Philippini) leaf of described deal, dry Folium Kaki and dry Folium Canarii Pimelae co-grinding, make tablet or capsule or make bag with the paper bag of making tea and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310480608.4A CN103494959B (en) | 2013-10-15 | 2013-10-15 | Drug for treating high blood pressure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310480608.4A CN103494959B (en) | 2013-10-15 | 2013-10-15 | Drug for treating high blood pressure |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103494959A true CN103494959A (en) | 2014-01-08 |
| CN103494959B CN103494959B (en) | 2015-04-01 |
Family
ID=49860282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310480608.4A Active CN103494959B (en) | 2013-10-15 | 2013-10-15 | Drug for treating high blood pressure |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103494959B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177533A (en) * | 2016-07-11 | 2016-12-07 | 佛山杰致信息科技有限公司 | A kind of hypertension health tea and processing technology thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102138600A (en) * | 2010-09-28 | 2011-08-03 | 阳城县析城山土特产开发有限公司 | Persimmon leaf tea and preparation method |
-
2013
- 2013-10-15 CN CN201310480608.4A patent/CN103494959B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102138600A (en) * | 2010-09-28 | 2011-08-03 | 阳城县析城山土特产开发有限公司 | Persimmon leaf tea and preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 梁燕玲等: "乌榄叶水提物对大鼠血压和心率的实验研究", 《江西医学院学报》, vol. 46, no. 3, 31 March 2006 (2006-03-31), pages 42 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106177533A (en) * | 2016-07-11 | 2016-12-07 | 佛山杰致信息科技有限公司 | A kind of hypertension health tea and processing technology thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103494959B (en) | 2015-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102919836B (en) | Health-care product capable of reducing blood glucose, releasing pressure, reducing lipid, relaxing bowel, beautifying, losing weight and resisting fatigue and production process thereof | |
| CN103211257B (en) | A kind of hypoglycemic apple vinegar health beverage and preparation method thereof | |
| CN102302149A (en) | Multi-panax healthcare food and preparation method thereof | |
| CN104286273A (en) | Application of dendrobium candidum and tea leaf product thereof | |
| CN107279923A (en) | ginseng composite fermentation nutrient powder and preparation method thereof | |
| CN100525791C (en) | Health product and medicine and their preparing method | |
| CN103461585B (en) | Qi tonifying and health preserving herbal tea | |
| CN103405657B (en) | Medicine for treating cough and preparation method thereof | |
| CN101467673A (en) | Compound ginseng health product and preparation method thereof | |
| CN104017715A (en) | Passion fruit vinegar and preparation method thereof | |
| CN107349332A (en) | A kind of deer horn glue oral liquid and preparation method thereof | |
| CN107095300A (en) | A kind of biological nutrition compound composition of auxiliary treatment diabetes | |
| CN104450470B (en) | A kind of three-bristle cudrania fruit health liquor and preparation method thereof | |
| CN106362007A (en) | Traditional Chinese medicine composition containing dendrobium huoshanense and achieving glucose lowering effect and preparation method thereof | |
| CN103494959B (en) | Drug for treating high blood pressure | |
| CN102823700A (en) | Preparation method of compound poria cocos and black garlic filled chocolate | |
| CN103100028A (en) | Soft capsule favorable for reducing alcoholic liver injury and preparation method thereof | |
| CN109275751A (en) | Folium cortex eucommiae blood-pressure decreasing tea and preparation method thereof | |
| CN107712890A (en) | A kind of antitoxic heart-soothing and sedative cream taste and preparation method thereof | |
| CN103393938B (en) | Traditional Chinese medicine composition for reducing blood sugar | |
| CN110496212A (en) | A kind of Chinese medicine composition and preparation method thereof improving wine poison constitution | |
| CN104256618A (en) | Food, health care product or medicine composition with blood sugar reduction function | |
| CN104524180A (en) | Maca compound tablet, and preparation method and applications thereof | |
| CN109463607A (en) | A kind of food digesting stomach fortifying, food and medicament dual-purpose solid beverage product of promoting the circulation of qi defaecation and preparation method thereof | |
| CN111084856A (en) | Traditional Chinese medicine preparation for treating hypertension and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |