CN103396974B - 用于高效乳酸生产的材料和方法 - Google Patents

用于高效乳酸生产的材料和方法 Download PDF

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Publication number
CN103396974B
CN103396974B CN201310012065.3A CN201310012065A CN103396974B CN 103396974 B CN103396974 B CN 103396974B CN 201310012065 A CN201310012065 A CN 201310012065A CN 103396974 B CN103396974 B CN 103396974B
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China
Prior art keywords
lactate
lactic acid
coli
strain
gene
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Expired - Fee Related
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CN201310012065.3A
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English (en)
Chinese (zh)
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CN103396974A (zh
Inventor
周胜德
朗尼·奥尼尔·英格拉姆
基尔内塔姆·T·尚穆加姆
洛兰·P·约马诺
塔米·B·格拉巴尔
乔纳森·C·穆尔
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University of Florida Research Foundation Inc
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University of Florida Research Foundation Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201310012065.3A 2005-08-10 2006-08-10 用于高效乳酸生产的材料和方法 Expired - Fee Related CN103396974B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US70688705P 2005-08-10 2005-08-10
US60/706,887 2005-08-10
US76157606P 2006-01-24 2006-01-24
US60/761,576 2006-01-24
US79961906P 2006-05-11 2006-05-11
US60/799,619 2006-05-11
CN2006101093329A CN1912107B (zh) 2005-08-10 2006-08-10 用于高效乳酸生产的材料和方法

Related Parent Applications (1)

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CN2006101093329A Division CN1912107B (zh) 2005-08-10 2006-08-10 用于高效乳酸生产的材料和方法

Publications (2)

Publication Number Publication Date
CN103396974A CN103396974A (zh) 2013-11-20
CN103396974B true CN103396974B (zh) 2016-12-07

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CN2006101093329A Expired - Fee Related CN1912107B (zh) 2005-08-10 2006-08-10 用于高效乳酸生产的材料和方法

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US (2) US7629162B2 (cg-RX-API-DMAC10.html)
EP (2) EP1760156B1 (cg-RX-API-DMAC10.html)
JP (2) JP4991205B2 (cg-RX-API-DMAC10.html)
CN (2) CN103396974B (cg-RX-API-DMAC10.html)
BR (1) BRPI0603072A (cg-RX-API-DMAC10.html)
DK (2) DK2305826T3 (cg-RX-API-DMAC10.html)
ES (2) ES2401339T3 (cg-RX-API-DMAC10.html)
PL (2) PL1760156T3 (cg-RX-API-DMAC10.html)

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ES2401339T3 (es) * 2005-08-10 2013-04-18 University Of Florida Research Foundation, Inc. Materiales y métodos para producción eficiente de ácido láctico
US8691539B2 (en) * 2007-03-20 2014-04-08 University Of Florida Research Foundation, Inc. Materials and methods for efficient succinate and malate production
US20090082600A1 (en) * 2007-06-06 2009-03-26 Shengde Zhou Native homoethanol Pathway for ethanol production in E. coli
EP2304039B1 (en) * 2008-06-17 2019-08-21 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
CN102333859B (zh) 2008-09-16 2015-04-22 三井化学株式会社 由来自植物的原料生产乳酸的方法及生产乳酸的细菌
US8993287B2 (en) * 2008-11-18 2015-03-31 University Of Florida Research Foundation, Inc. Biocatalysts and methods for conversion of hemicellulose hydrolysates to biobased products
US8715972B2 (en) * 2009-02-18 2014-05-06 Bio-Energy Corporation Homolactic fermentation from pentose
EP2414505B1 (en) 2009-04-02 2019-05-22 University of Florida Research Foundation, Inc. Engineering the pathway for succinate production
US9169485B2 (en) 2009-06-23 2015-10-27 Bp Corporation North America Inc. Recombinant ethanologenic bacteria comprising a urease gene
BR112012002153A2 (pt) 2009-07-30 2015-09-15 Metabolic Explorer Sa metilglioxal sintase mutante (mgs) para a produção de material bioquímico por fermentação
WO2011063157A2 (en) 2009-11-18 2011-05-26 Myriant Technologies Llc Organic acid production in microorganisms by combined reductive and oxidative tricarboxylic acid cycle pathways
CN102686718B (zh) 2009-11-18 2014-12-24 麦兰特公司 产生有机酸的大肠杆菌菌株的代谢进化
US10017793B2 (en) 2009-11-18 2018-07-10 Myriant Corporation Metabolic evolution of Escherichia coli strains that produce organic acids
US9017976B2 (en) 2009-11-18 2015-04-28 Myriant Corporation Engineering microbes for efficient production of chemicals
CN103502432A (zh) 2010-11-22 2014-01-08 诺维信股份有限公司 用于生产3-羟基丙酸的组合物和方法
WO2013009679A2 (en) 2011-07-08 2013-01-17 University Of Florida Research Foundation, Inc. Over-expression of a putative oxidoreductase (ucpa) for increasing furfural or 5-hydroxymethylfurfural tolerance
KR101928688B1 (ko) 2011-07-22 2018-12-13 피티티지씨 이노베이션 아메리카 코포레이션 유기산으로의 글리세롤의 발효
WO2014017469A1 (ja) * 2012-07-23 2014-01-30 三井化学株式会社 Ｄ－乳酸の生産方法、ポリマーの生産方法およびポリマー
EP2925873B1 (en) 2012-11-30 2017-07-12 Novozymes, Inc. 3-hydroxypropionic acid production by recombinant yeasts
KR20140075044A (ko) 2012-12-07 2014-06-19 삼성전자주식회사 불포화 카르복실산의 제조방법
CN104278003B (zh) * 2013-07-12 2018-12-18 中国科学院天津工业生物技术研究所 生产d-乳酸的重组大肠杆菌及其应用
US9845484B2 (en) 2013-07-31 2017-12-19 Novozymes A/S 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase
PL3194592T3 (pl) * 2014-07-23 2021-02-08 Purac Biochem Bv Zmodyfikowane genetycznie bakterie termofilne wytwarzające kwas (r)mlekowy
EP2977471A1 (en) * 2014-07-23 2016-01-27 PURAC Biochem BV Genetic modification of (S)-lactic acid producing thermophilic bacteria
KR102581464B1 (ko) 2015-05-28 2023-09-21 삼성전자주식회사 락테이트 데히드로게나제 변이체를 스크리닝하는 방법, 락테이트 데히드로게나제 변이체, 상기 변이체를 포함하는 폴리뉴클레오티드, 벡터, 미생물, 및 상기 미생물을 이용하여 락테이트를 생산하는 방법
JP2017121184A (ja) * 2016-01-04 2017-07-13 花王株式会社 変異リゾプス属菌
WO2019159011A2 (en) 2018-02-16 2019-08-22 Ptt Global Chemical Public Company Limited Microorganisms and processes for lactic acid production
CN109280652A (zh) * 2018-09-13 2019-01-29 四川自豪时代药业有限公司 一种外源高表达乳酸脱氢酶突变体的高密度发酵方法
CN109321590B (zh) * 2018-10-19 2022-06-21 北京化工大学 利用乙酸生产l-乳酸的基因工程菌及其构建方法和应用

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CN1156180A (zh) * 1995-09-05 1997-08-06 底古萨股份公司 用大肠杆菌生产色氨酸
CN1912107B (zh) * 2005-08-10 2013-03-13 佛罗里达大学研究基金会公司 用于高效乳酸生产的材料和方法

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CN1156180A (zh) * 1995-09-05 1997-08-06 底古萨股份公司 用大肠杆菌生产色氨酸
CN1912107B (zh) * 2005-08-10 2013-03-13 佛罗里达大学研究基金会公司 用于高效乳酸生产的材料和方法

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From famine to feast: the role of methylglyoxal production in Escherichia coli;S. Totemeyer et al.;《Molecular Microbiology》;19981231;第27卷(第3期);第553-562页 *
Production of Optically Pure d-Lactic Acid in Mineral Salts Medium by Metabolically Engineered Escherichia coli W3110;Shengde Zhou et al.;《APPLIED AND ENVIRONMENTAL MICROBIOLOGY》;20030131;第69卷(第1期);第399-407页 *

Also Published As

Publication number Publication date
EP1760156A3 (en) 2007-04-04
EP2305826A1 (en) 2011-04-06
ES2573980T3 (es) 2016-06-13
CN103396974A (zh) 2013-11-20
JP5798441B2 (ja) 2015-10-21
JP2007049993A (ja) 2007-03-01
ES2401339T3 (es) 2013-04-18
BRPI0603072A (pt) 2007-03-27
DK1760156T3 (da) 2013-03-18
EP2305826B1 (en) 2016-03-30
PL1760156T3 (pl) 2013-05-31
DK2305826T3 (en) 2016-06-27
US8426191B2 (en) 2013-04-23
US7629162B2 (en) 2009-12-08
JP4991205B2 (ja) 2012-08-01
US20100203602A1 (en) 2010-08-12
PL2305826T3 (pl) 2016-10-31
EP1760156A9 (en) 2007-04-25
US20070037265A1 (en) 2007-02-15
CN1912107A (zh) 2007-02-14
EP1760156A2 (en) 2007-03-07
EP1760156B1 (en) 2012-12-19
CN1912107B (zh) 2013-03-13
JP2012010715A (ja) 2012-01-19

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