PL3194592T3 - Zmodyfikowane genetycznie bakterie termofilne wytwarzające kwas (r)mlekowy - Google Patents

Zmodyfikowane genetycznie bakterie termofilne wytwarzające kwas (r)mlekowy

Info

Publication number
PL3194592T3
PL3194592T3 PL15741963T PL15741963T PL3194592T3 PL 3194592 T3 PL3194592 T3 PL 3194592T3 PL 15741963 T PL15741963 T PL 15741963T PL 15741963 T PL15741963 T PL 15741963T PL 3194592 T3 PL3194592 T3 PL 3194592T3
Authority
PL
Poland
Prior art keywords
lactic acid
genetically modified
acid producing
thermophilic bacteria
producing thermophilic
Prior art date
Application number
PL15741963T
Other languages
English (en)
Inventor
Marinus Petrus Machielsen
Mariska Van Hartskamp
Richard Van Kranenburg
Original Assignee
Purac Biochem Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purac Biochem Bv filed Critical Purac Biochem Bv
Publication of PL3194592T3 publication Critical patent/PL3194592T3/pl

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56Lactic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01027L-Lactate dehydrogenase (1.1.1.27)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01028D-Lactate dehydrogenase (1.1.1.28)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008Phosphate acetyltransferase (2.3.1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01054Formate C-acetyltransferase (2.3.1.54), i.e. pyruvate formate-lyase or PFL
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07Nucleotidyltransferases (2.7.7)
    • C12Y207/07006DNA-directed RNA polymerase (2.7.7.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/03Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03003Methylglyoxal synthase (4.2.3.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL15741963T 2014-07-23 2015-07-13 Zmodyfikowane genetycznie bakterie termofilne wytwarzające kwas (r)mlekowy PL3194592T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14178144 2014-07-23
PCT/EP2015/065990 WO2016012296A1 (en) 2014-07-23 2015-07-13 Genetically modified (r)-lactic acid producing thermophilic bacteria
EP15741963.1A EP3194592B1 (en) 2014-07-23 2015-07-13 Genetically modified (r)-lactic acid producing thermophilic bacteria

Publications (1)

Publication Number Publication Date
PL3194592T3 true PL3194592T3 (pl) 2021-02-08

Family

ID=51211697

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15741963T PL3194592T3 (pl) 2014-07-23 2015-07-13 Zmodyfikowane genetycznie bakterie termofilne wytwarzające kwas (r)mlekowy

Country Status (12)

Country Link
US (1) US10731186B2 (pl)
EP (1) EP3194592B1 (pl)
JP (1) JP6637026B2 (pl)
KR (1) KR101980069B1 (pl)
CN (1) CN106574236B (pl)
AU (1) AU2015294136C9 (pl)
BR (1) BR112017000846B1 (pl)
CA (1) CA2955717C (pl)
ES (1) ES2821418T3 (pl)
PL (1) PL3194592T3 (pl)
PT (1) PT3194592T (pl)
WO (1) WO2016012296A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018109101A1 (en) 2016-12-14 2018-06-21 Wageningen Universiteit Thermostable cas9 nucleases
US20210403928A1 (en) * 2018-11-30 2021-12-30 Utilization Of Carbon Dioxide Institute Co., Ltd. Lactic Acid-Producing Hydrogenophilus Bacterium Transformant
CA3148422A1 (en) 2019-08-09 2021-02-18 Utilization Of Carbon Dioxide Institute Co., Ltd. A recombinant hydrogenophilus bacterium producing lactic acid
CN111154705B (zh) * 2020-01-07 2021-06-29 中国科学院微生物研究所 热葡萄糖苷酶地芽孢杆菌工程菌及其构建方法及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4336082B2 (ja) 2001-05-29 2009-09-30 花王株式会社 宿主微生物
GB0117551D0 (en) 2001-07-18 2001-09-12 Elsworth Biotech Ltd Lastic acid production
US9497168B2 (en) 2002-07-30 2016-11-15 Avaya Inc. Method and apparatus for supporting communications between a computing device within a network and an external computing device
CN1809631B (zh) 2003-06-18 2010-05-26 帝斯曼知识产权资产管理有限公司 用不能形成芽孢的微生物来生产泛酸盐/酯的方法
US7098009B2 (en) 2004-03-04 2006-08-29 University Of Florida Research Foundation, Inc. Production of chemicals from lignocellulose, biomass or sugars
DK1760156T3 (da) 2005-08-10 2013-03-18 Univ Florida Materialer og fremgangsmåder til effektiv mælkesyrefremstilling
WO2007120198A2 (en) 2005-11-08 2007-10-25 University Of Florida Research Foundation, Inc. Materials and methods for improved microbial production of organic compounds
EP1989309B1 (en) 2006-01-24 2011-08-31 PURAC Biochem BV Genetic modification of homolactic thermophilic bacilli
CA2818680A1 (en) 2010-11-22 2012-05-31 Qingzhao Wang Engineering of thermotolerant bacillus coagulans for production of d(-)-lactic acid
KR101438882B1 (ko) 2012-04-24 2014-09-05 씨제이제일제당 (주) 신규한 d형 젖산 생산균주
JPWO2014017469A1 (ja) 2012-07-23 2016-07-11 三井化学株式会社 D−乳酸の生産方法およびポリマーの生産方法

Also Published As

Publication number Publication date
AU2015294136C1 (en) 2018-10-25
CN106574236B (zh) 2020-12-11
EP3194592A1 (en) 2017-07-26
CA2955717C (en) 2020-09-22
CN106574236A (zh) 2017-04-19
US20170275656A1 (en) 2017-09-28
EP3194592B1 (en) 2020-07-08
US10731186B2 (en) 2020-08-04
AU2015294136B2 (en) 2018-04-26
KR20170019467A (ko) 2017-02-21
AU2015294136C9 (en) 2019-05-02
BR112017000846B1 (pt) 2024-01-16
BR112017000846A2 (pt) 2018-07-31
KR101980069B1 (ko) 2019-05-20
PT3194592T (pt) 2020-09-25
AU2015294136A1 (en) 2017-02-09
JP2017523778A (ja) 2017-08-24
WO2016012296A1 (en) 2016-01-28
ES2821418T3 (es) 2021-04-26
CA2955717A1 (en) 2016-01-28
JP6637026B2 (ja) 2020-01-29

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