CN103364236B - Device and method for determining parameters of push pieces, push piece dyeing machine and method for manufacturing blood smear - Google Patents
Device and method for determining parameters of push pieces, push piece dyeing machine and method for manufacturing blood smear Download PDFInfo
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Abstract
The invention discloses a device and method for determining parameters of a push piece, a push piece dyeing machine and a method for manufacturing a blood smear. The push piece dyeing machine comprises a blood transmission device, the push piece, a blood characteristic acquisition unit, a push piece parameter determining unit and a motion control unit, wherein the blood characteristic acquisition unit transmits a detection signal to a blood sample transmitted by the blood transmission device and receives a detection signal acting on the blood sample; the push piece parameter determining unit receives the detection signal output by the blood characteristic acquisition unit and determines and outputs the push piece parameters according to the detection signal; the motion control unit receives the push piece parameters output by the push piece parameter determining unit and controls relative motion of the push piece and a blood glass slide according to the push piece parameters. According to the method and the device, the operations of determining the push piece parameters and finishing manufacture of the blood smear can be performed in an independent push piece dyeing system or equipment, the system or the equipment is not required to be in cascade connection with a hematology analyzer to acquire related blood parameters, the process of determining the push piece parameters is simplified, and the complexity of the whole push piece dyeing machine is reduced in the aspects of structure and system operation.
Description
Technical field
The present invention relates to push jack staining technique field, more particularly, to a kind of device determining blood smear push jack parameter and side
Method.
Background technology
In push jack coloring system, need the characteristic according to blood sample to be measured（For example：Blood viscosity, blood rbc hematocrit
Deng）, the push jack parameter of adjustment machine（For example：Push jack speed, push jack angle, the setting amount of bleeding, drop of blood diffusion time etc.）, with true
Protect drop of blood to be smeared by uniform, smooth on slide, complete subsequent treatment afterwards again（For example：Blood film is dried, dyes etc.）, obtain
Preferably blood smear, completes microscopy for doctor.
Traditional method is to cascade push jack staining machine with cellanalyzer, the blood characteristics that cellanalyzer is recorded
Result passes to sheet pushing machine, to determine push jack parameter.The method is due to being confined to cascade system, therefore is dfficult to apply to individually push away
Piece machine, the method system is more complicated, relatively costly simultaneously.
Content of the invention
The present invention provides a kind of device determining blood smear push jack parameter, method and push jack staining machine, makes push jack staining machine
Do not need to can determine that the push jack parameter of blood smear with cellanalyzer cascade.
The present invention provides a kind of blood smear making method, and the method using above-mentioned determination push jack parameter makes blood smear.
According to the first aspect of the invention, a kind of push jack staining machine is provided, including：
Blood-transmitted device, for gathering blood sample to be measured and blood sample being discharged to blood smear carrier, described blood-transmitted
Device includes blood container；
Push jack；
Blood characteristics collecting unit, it is arranged near blood container, including transmitting terminal and receiving terminal, described transmitting terminal
To the blood sample transmitting detection signal in blood container, described receiving terminal is arranged in detection signal transmission path, receives menses
The detection signal after blood sample effect in liquid container；
Push jack parameter determination unit, is connected with blood characteristics collecting unit, receives the warp of blood characteristics collecting unit output
Detection signal after blood sample effect, determines push jack parameter according to the detection signal after acting on through blood sample and exports；
Motion control unit, receives the push jack parameter of push jack parameter determination unit output, according to push jack state modulator
The motion of push jack.
According to the second aspect of the invention, a kind of method determining blood smear push jack parameter is provided, including：
Blood-transmitted device is controlled to draw blood sample to be measured in the blood container of blood-transmitted device；
It is arranged on the blood characteristics collecting unit near blood container to believe to the blood sample transmitting detection in blood container
Number, and receive the detection signal after the blood sample effect in blood container；
Push jack parameter is determined according to the detection signal after blood sample effect.
According to the third aspect of the invention we, a kind of method making blood smear is provided, including：
Blood-transmitted device is controlled to draw blood sample to be measured in the blood container of blood-transmitted device；
It is arranged on the blood characteristics collecting unit near blood container to believe to the blood sample transmitting detection in blood container
Number, and receive the detection signal after the blood sample effect in blood container；
Push jack parameter determination unit determines push jack parameter according to the detection signal after blood sample effect；
Blood in blood container is discharged set amount on blood smear carrier；
The motion of the push jack state modulator push jack that motion control unit determines according to push jack parameter determination unit, thus complete
The making of blood smear.
According to the fourth aspect of the invention, a kind of device determining blood smear push jack parameter is provided, including：
Blood-transmitted device, for gathering blood sample to be measured, described blood-transmitted device includes blood container；
Blood characteristics collecting unit, it is arranged near blood container, including transmitting terminal and receiving terminal, described transmitting terminal
To the blood sample transmitting detection signal in blood container, described receiving terminal is arranged in detection signal transmission path, receives menses
The detection signal after blood sample effect in liquid container；
Push jack parameter determination unit, is connected with blood characteristics collecting unit, receives the blood of blood characteristics collecting unit output
Detection signal after sample effect, determines push jack parameter according to the detection signal after blood sample effect.
The application detects to the characteristic of blood sample during blood sample is sampled and transmitted, according to testing result
Be determined for compliance with the push jack parameter of this blood sample characteristic, the determination of push jack parameter and complete the making of blood smear can be in independent pushing away
Carry out on piece coloring system or equipment, need not cascade with cellanalyzer, simplify the determination process of push jack parameter, in structure
With the complexity that whole push jack staining machine is reduced on system operatio.
Brief description
Fig. 1 is the structural representation of an embodiment of the present invention；
Fig. 2 is the blood smear making flow chart of an embodiment of the present invention；
Fig. 3 is the graph of relation of detection light intensity and push jack parameter in a kind of embodiment；
Fig. 4 is to determine blood sample push jack parameter schematic diagram to be measured using the curve in Fig. 3；
Fig. 5 is blood sample characteristic and push jack parameter lookup table；
Fig. 6 is the effect diagram of the blood smear making；
Fig. 7 is the blood smear measuring the speed preparation that different qualities blood sample obtains using the method for the present invention one instantiation
Sample schematic diagram；
Fig. 8 is the characteristic parameter of the sample of different qualities blood sample in Fig. 7.
Specific embodiment
Combine accompanying drawing below by specific embodiment the present invention is described in further detail.
In the embodiment of the present application, the blood according to different qualities needs different push jack parameters to be fabricated to Qualified Blood painting
The requirement of piece, it is first determined go out the characteristic of blood sample to be measured, the characteristic of blood sample to be measured can be the red thin of blood viscosity and blood
At least one of characteristics such as born of the same parents' hematocrit, those skilled in the art can also select other characteristics of blood sample as needed.True
After making the characteristic of blood sample to be measured, characteristic according to blood sample to be measured by table look-up or matched curve by way of determine that push jack is joined
Number.
The blood of different qualities is different to the degree of absorption of some detection signals, in the embodiment of the present invention, is treated by detection
The characteristic to determine blood sample to be measured for the absorbability of survey blood sample.Its central scope is：Detection signal is launched to blood sample to be measured, receives warp
Detection signal after blood sample effect, the size of the detection signal after acting on through the blood sample characteristic to characterize blood sample to be measured, thus
Push jack parameter can be determined at the size of the detection signal after blood sample effect according to this.
In one embodiment, determine that the device of blood smear push jack parameter includes blood-transmitted device, blood characteristics collection
Unit and push jack parameter determination unit.Blood-transmitted device is used for gathering blood sample to be measured, and described blood-transmitted device includes blood
Container, the blood sample of blood-transmitted device collection is placed in blood container；Blood characteristics collecting unit is arranged on blood and accommodates
Near device, for the blood sample in blood container is carried out with Characteristics Detection, blood characteristics collecting unit includes transmitting terminal and reception
End, described transmitting terminal is arranged on detection signal transmission road to the blood sample transmitting detection signal in blood container, described receiving terminal
On footpath, receive the detection signal after absorbing through the blood sample in blood container；Push jack parameter determination unit is gathered with blood characteristics
Unit is connected, and receives the blood examination signal of blood characteristics collecting unit output, determines push jack parameter according to blood examination signal.
When the push jack parameter needing to obtain blood sample to be measured, blood-transmitted device transmits blood sample to be measured to the blood of blood-transmitted device first
In liquid container, it is arranged on the blood characteristics collecting unit near blood container and launches to the blood sample to be measured in blood container
Detection signal, and receive the detection signal after absorbing through the blood sample in blood container, thus the detection after being absorbed according to blood sample
Signal determines push jack parameter.
In one embodiment, include blood using the push jack staining machine of the device of above-mentioned determination blood smear push jack parameter to pass
Defeated device, blood smear push jack unit, blood characteristics collecting unit, push jack parameter determination unit and motion control unit.Blood passes
Defeated device is used for gathering blood sample to be measured and blood sample being discharged to blood smear carrier, and it has the blood for accommodating blood sample to be measured
Container；Blood characteristics collecting unit is arranged near blood container, and including transmitting terminal and receiving terminal, described transmitting terminal is to blood
Blood sample transmitting detection signal in liquid container, described receiving terminal is arranged in detection signal transmission path, receives and holds through blood
Detection signal after the blood sample effect received in device；Push jack parameter determination unit is connected with blood characteristics collecting unit, receives blood
Detection signal after the blood sample effect of characteristic collecting unit output, determines push jack parameter simultaneously according to the detection signal after blood sample effect
Output；Motion control unit receives the push jack parameter of push jack parameter determination unit output, makes blood according to push jack state modulator and applies
The motion of piece push jack.
In a kind of instantiation, blood-transmitted device includes power provides unit and blood container, blood container
Can be sampling needle, it can be syringe that power provides unit, provide blood sample to suck and discharge the power of blood container, sampling
Pin is coupled to syringe, and the transmitting terminal of blood characteristics collecting unit is separately positioned on the relative both sides of sampling needle with receiving terminal.
Syringe is connected with motion control unit, can move under the control of motion control unit, such as motion control unit control
Syringe movement processed, to change the pressure within sampling needle, makes sampling needle draw blood sample or discharge blood sample.When sampling needle draws blood
After sample, transmitting terminal arrives to the blood sample transmitting detection signal in blood container, transmission signal after blood sample absorption for the detection signal
Reach receiving terminal, the transmission signal detecting is converted to electric signal output to push jack parameter determination unit, push jack parameter by receiving terminal
Determining unit determines push jack parameter according to the signal of telecommunication.
In another kind of instantiation, blood-transmitted device includes syringe and blood container, and blood container includes
Sampling needle and the blood-transmitted pipe being connected with sampling needle tail end, the other end of blood-transmitted pipeline is coupled to syringe, described
The transmitting terminal of blood characteristics collecting unit is separately positioned on the relative both sides of blood-transmitted pipeline with receiving terminal.Syringe is in fortune
The control of dynamic control unit moves down movable property and gives birth to negative pressure, makes sampling needle draw enough blood samples, and makes blood sample enter blood-transmitted pipe
Road, now to the blood sample transmitting detection signal in blood-transmitted pipeline, detection signal passes through blood sample and reaches receiving terminal, connects transmitting terminal
Receiving end receives the detection signal after blood sample effect, and detection signal is converted to electric signal output to push jack parameter determination list
Unit, push jack parameter determination unit determines push jack parameter according to the signal of telecommunication.In another embodiment, blood container can also
It is blood sample transfer tube, do not include sampling needle.Or, blood sample container and power provide unit direct Rhizoma Nelumbinis connection, for example small-sized note
Emitter, blood is inhaled in transparent needle tubing, and the transmitting terminal of described blood characteristics collecting unit and receiving terminal are separately positioned on injection
Device needle tubing both sides, it is also possible to obtain detection signal.As long as it will be appreciated by those skilled in the art that can be in blood-transmitted process
In, the part accommodating blood to be measured is all the blood container of indication of the present invention.Power in above example provides unit to carry
For the suction of power drive blood sample, can also be micro air pump, the dosing pump such as electromagnetic pump, as long as wanting of quantitative accuracy can be met
Ask, can be used in the present invention.
The blood flow volume that blood-transmitted device is drawn can be fixing amount, as long as the uptake of blood sample to be measured is sufficiently used for blood
Liquid characteristic collecting unit detects and more than the blood flow volume making required for blood smear.Blood-transmitted device is making blood smear
When the blood flow volume discharged can be fixing amount it is also possible to relevant with the characteristic of blood sample to be measured（The i.e. characteristic according to blood sample to be measured
Determine the output of blood）.When the uptake of blood and output being fixing, can be by the means control mechanically or electrically controlling
The absorption of blood-transmitted device processed and discharge, when the output that needs determine blood according to the characteristic of blood sample to be measured, can be true
Determine to determine the amount of bleeding during push jack parameter, control syringe to hold blood by motion control unit according to the amount of bleeding in push jack parameter
The blood received in device discharges set amount on blood smear carrier.
The amount of bleeding, diffusion time, push jack angle and push jack speed can be included using the push jack parameter that above-described embodiment determines
At least one in degree, the amount of bleeding is used for defining the blood flow volume of blood-transmitted device discharge；Be used for diffusion time defining push jack and
The drop of blood stationary contact time, touch drop of blood to the time of push jack setting in motion from push jack, control drop of blood along push jack edge
Range of scatter, thus control the width of blood film；Push jack angle is used for defining the angle of inclination of push jack；Push jack speed is used for defining and pushes away
The speed of piece translation.After determining push jack parameter, push jack parameter is sent to motion control unit by push jack parameter determination unit,
Blood in blood container is discharged set amount to blood smear carrier according to push jack state modulator syringe by motion control unit
On, then motion control unit makes the motion of blood smear push jack according to push jack state modulator, makes push jack according to the inclination setting
The time of contact of angle and blood smear carrier and speed of related movement complete the operation of blood smear push jack.
The detection signal of blood characteristics collecting unit transmitting can be optical, electromagnetic ripple or ultrasound wave, corresponding blood characteristics
Collecting unit can be photoelectric testing sensor, electromagnetic sensor or Ultrasound Instrument.
So that blood sample characteristic is detected by the light detecting signal as a example mistake to push jack staining machine and its making blood smear below
Journey is described in detail.
The blood of different qualities is different to the degree of absorption of optical signal, as more in blood endoparticle thing（For example：In blood relatively
Big lipid granule）, or as blood inner cell increasing number（For example：Erythrocytosis, leukocytosiss etc.）When, it is to light
Absorbability is stronger, and when that is, light irradiation is on this blood, the light intensity of transmission is less；Whereas if blood endoparticle thing or cell
Less, then this blood is weaker to the absorbability of light, and when light irradiation is on this blood, the light intensity of transmission is larger.In the present embodiment
In, photoelectric testing sensor and push jack parameter determination unit are increased on push jack staining machine, by testing blood sample to optical signal
Degree of absorption, so that it is determined that go out the push jack parameter of this blood sample suitable.
Refer to Fig. 1, push jack staining machine include sampling needle 1, blood-transmitted pipe 2, photoelectric testing sensor 3, syringe 7,
Push jack parameter determination unit 8, motion control unit 9 and push jack 10.Blood-transmitted pipe 2 connects with the tail end of sampling needle 1, and blood passes
The other end of defeated pipe 2 is coupled with syringe 7, and such as blood-transmitted pipe 2 and syringe 7 constitute the blood-transmitted pipeline of sealing, from
In can realize absorption and the transmission of blood sample by driving the motor of syringe.The transmitting terminal of photoelectric testing sensor 3 and reception
End is separately positioned on the relative both sides of blood-transmitted pipe 2, and blood-transmitted pipe 2 is made by transparent material, or at least in light electric-examination
The detection zone surveying sensor is made by transparent material, or at least material is relative in the detection spectral regions of photoelectric testing sensor
Transparent（For example, when this detection signal frequency spectrum is ultra-violet (UV) band or ultrared, the material of detection zone is not necessarily what naked eyes can see below
Transparent material）.The outfan of photoelectric testing sensor 3 is electrically connected to push jack parameter determination unit 8, push jack parameter determination unit 8
Outfan be coupled to motion control unit 9, motion control unit 9 is also coupled to syringe 7 and push jack 10, to control note
Emitter 7 and the motion of push jack 10.
When needing to make blood smear, the work process of this push jack staining machine is as follows：As shown in Fig. 2 comprising the following steps：
Step S11, gathers blood sample.Sampling needle 1 enters in the test tube 13 of dress blood, controls injection by motion control unit 9
Device 7, blood is drawn to blood-transmitted pipe 2.
Step S12, the characteristic of detection blood sample.When blood transportation is through position 6 to be measured（Dotted arrow represents blood motion
Direction）, the light source 4 of photoelectric testing sensor 3 sends light beam, and the wavelength of light can set as needed, and light beam is radiated at this blood
On, and received by the optical-electrical converter 5 of photoelectric testing sensor 3, and converting thereof into the signal of telecommunication, the amplitude of this signal of telecommunication is big
Little, that is, characterize this blood sample characteristic.With blood rbc hematocrit（HCT）As a example, when HCT value is bigger, internal red cell proportion
Bigger, stronger to the absorbability of light, then the light intensity that photoelectric testing sensor detects is less, and the electrical signal amplitude changing into is got over
Little；Vice versa.
Step S13, determines push jack parameter according to blood sample characteristic.Push jack parameter determination unit 8 obtains according to optical-electrical converter 5
Signal of telecommunication size it may be determined that go out this blood sample be suitable for push jack parameter, for example pass through electrical signal amplitude table corresponding with push jack parameter
Or matched curve can find to should the signal of telecommunication push jack parameter.Taking push jack speed as a example, the light intensity of detection is converted to voltage,
Voltage as shown in Figure 3 and the matched curve figure of push jack speed, voltage is less, and the light intensity of detection is also less, represents that blood is more viscous
Thick, the push jack speed of its application should be less；Conversely, voltage is bigger, the light intensity of detection is also bigger, represents that blood, blood viscosity is got over
Little, the push jack speed of its application should be bigger.As shown in figure 4, when learning voltage signal amplitude, in the plan of voltage and push jack speed
Close curve chart and push jack speed can be determined by electrical signal amplitude value.Will by push jack parameter determination unit 8 after determining push jack parameter
It passes to motion control unit 9.
Step S14, makes blood smear according to push jack parameter.Motion control unit 9 receives push jack parameter determination unit 8
After the information sent, complete the action setting, that is, first according to the amount of the bleeding state modulator syringe 7 in push jack parameter by sucked blood liquid
Discharge set amount, drop in blood smear carrier（Such as microscope slide）On 11（Produce the drop of blood 12 treating push jack）, according still further to push jack ginseng
The result that number calculates, controls the motion of push jack 10, controls push jack contact drop of blood first, according to control diffusion time in push jack parameter
The time that drop of blood processed spreads along push jack edge, after arriving diffusion time, incline according to the push jack Angle ambiguity push jack in push jack parameter
Tiltedly, and according to the push jack speed determining produce the relative motion of blood smear push jack and blood smear carrier, so that drop of blood is in push jack
Promotion under smeared into blood film.Finally make time, the push jack speed that push jack 10 contacted with slide 11 according to push jack parameter determination
Degree, push jack angle etc. complete the making of blood smear, obtain satisfactory blood smear.
The preparation method of electrical signal amplitude table corresponding with push jack parameter and matched curve is as follows：
Step 1：Experiment blood sample using different qualities.Different blood characteristics it is adaptable to different push jack parameter, because
This, can be by the clinical blood sample directly obtaining different qualities or, test sample as system；
Step 2：Light intensity after measurement different qualities blood sample effect.The blood sample of the different qualities of testing procedure 1 gained respectively,
The transmission light intensity result obtaining under this device, in this, as the foundation of the push jack parameter determining different qualities blood, with light intensity
As a example being converted into voltage signal, statistics different qualities blood sample corresponding detection light intensity conversion voltage value, obtain the form in Fig. 5,
Can get the abscissa in Fig. 3 by the magnitude of voltage in form.
Step 3：Determine the relation of detection light intensity and push jack parameter.By the blood sample of the different qualities of step 1 gained, by reality
Test and determine the push jack parameter being suitable for, can get the electrical signal amplitude table corresponding with push jack parameter in Fig. 5.Taking push jack speed as a example,
By the measured result in Fig. 5 form, count different qualities blood sample corresponding push jack speed, i.e. vertical coordinate in Fig. 3, and this is pushed away
Piece parameter is corresponding with detection light intensity, and the relation curve of both matchings can get the electrical signal amplitude shown in Fig. 3 and push jack parameter
Matched curve.Approximating method can adopt existing approximating method, for example, can adopt polynomial fitting method.
For certain blood sample to be measured, after obtaining its detection light intensity result, just can pass through step 3 gained relation, determine that this is treated
Survey the push jack parameter of blood sample.Illustrate, randomly select a blood sample to be measured, record its light intensity under this device and be converted into voltage
Signal value is 0.1305V, it may be determined that the push jack speed that it is suitable for is 131mm/s under the relation curve that step 3 obtains, such as Fig. 4
Shown.With the speed of this determination, carry out actual push jack, the result obtaining is as shown in Figure 6.Fig. 7 is to measure 4 not using the method
The blood smear sample of the speed preparation obtaining with characteristic blood sample, as can be seen from the figure no matter sample feature difference itself have many
Greatly, but suitable push jack effect can be obtained through the method change push jack speed（Fig. 8 is the characteristic parameter of these samples）.
In addition to blood sample characteristic being detected using optical signal in above-described embodiment, electromagnetic wave or ultrasonic can also be adopted
Ripple detects to blood sample characteristic, receives the electromagnetic wave or ultrasonic after blood sample effect on electromagnetic wave or ultrasonic transmission path
The signal of ripple, and detection signal intensity, the signal after blood sample effect can be after blood sample transmission, reflection, scattering or refraction
Detection signal.Correspondingly, detection zone can be made up of the transparent material of the frequency spectrum of detection signal relatively, as long as described transparent
It is that detection signal can pass through detection zone, be not necessarily the transparent material that naked eyes can see below.
Above content is to further describe it is impossible to assert this with reference to specific embodiment is made for the present invention
Bright it is embodied as being confined to these explanations.For general technical staff of the technical field of the invention, do not taking off
On the premise of present inventive concept, some simple deduction or replace can also be made, all should be considered as belonging to the protection of the present invention
Scope.
Claims (13)
1. a kind of push jack staining machine is it is characterised in that include：
Blood-transmitted device, for gathering blood sample to be measured and blood sample being discharged to blood smear carrier, described blood-transmitted device
Including blood container；
Push jack；
Blood characteristics collecting unit, it is arranged near blood container, and including transmitting terminal and receiving terminal, described transmitting terminal is to blood
Blood sample transmitting detection signal in liquid container, described receiving terminal is arranged in detection signal transmission path, receives and holds through blood
Detection signal after the blood sample effect received in device；
Push jack parameter determination unit, is connected with blood characteristics collecting unit, receive blood characteristics collecting unit output through blood sample
Detection signal after effect, determines push jack parameter according to the detection signal after acting on through blood sample and exports；
Motion control unit, receives the push jack parameter of push jack parameter determination unit output, push jack according to push jack state modulator
Motion.
2. push jack staining machine as claimed in claim 1 is it is characterised in that described push jack parameter determination unit is according to blood characteristics
Determine push jack parameter with push jack parameter lookup table or matching characteristic curve, described push jack parameter includes the amount of bleeding, diffusion time, pushes away
At least one in piece angle and push jack speed.
3. push jack staining machine as claimed in claim 1 is it is characterised in that described blood-transmitted device and motion control unit phase
Even, described motion control unit controls described blood-transmitted device that blood sample is sucked blood container, and is bled according to predetermined
The amount of bleeding in amount or push jack parameter controls described blood-transmitted device that the blood in blood container is discharged set amount to blood
On smear carrier.
4. push jack staining machine as claimed in claim 2 is it is characterised in that described blood-transmitted device and motion control unit phase
Even, described motion control unit controls described blood-transmitted device that blood sample is sucked blood container, and is bled according to predetermined
The amount of bleeding in amount or push jack parameter controls described blood-transmitted device that the blood in blood container is discharged set amount to blood
On smear carrier.
5. push jack staining machine as claimed in claim 1 provides list it is characterised in that described blood-transmitted device also includes power
Unit, described power provides unit to be connected with motion control unit, and its clutch end is coupled to blood container, and described power carries
For the control of unit action response motion control unit, arrange by blood sample suction blood container or by the blood in blood container
Go out set amount to blood smear carrier.
6. push jack staining machine as claimed in claim 5 is it is characterised in that described blood container includes sampling needle, described blood
The transmitting terminal of liquid characteristic collecting unit and receiving terminal are distributed near sampling needle, and the tail end of described sampling needle is coupled to power to be provided
Unit；Or the blood-transmitted pipe that described blood container is included sampling needle and is connected with sampling needle tail end, described blood-transmitted
Pipeline one end is connected with sampling needle tail end, the other end be coupled to power provide unit, described blood characteristics collecting unit send out
Penetrate end and receiving terminal is distributed in both sides or the sampling needle both sides of blood-transmitted pipeline；Or described blood container includes blood and passes
Defeated pipe, the tail end of blood-transmitted pipeline is coupled to power provides unit, the transmitting terminal of described blood characteristics collecting unit and reception
End is distributed in the both sides of blood-transmitted pipeline.
7. the push jack staining machine as any one of claim 1-6 is it is characterised in that described blood characteristics collecting unit is sent out
The detection signal penetrated is optical, electromagnetic ripple or ultrasound wave.
8. push jack staining machine as claimed in claim 7 is it is characterised in that described blood characteristics collecting unit passes for Photoelectric Detection
Sensor, described blood container at least the detection zone of photoelectric testing sensor by relatively detect frequency spectrum transparent material make.
9. a kind of use push jack staining machine determines the method for blood smear push jack parameter it is characterised in that described push jack staining machine bag
Include：
Blood-transmitted device, described blood-transmitted device includes blood container；
Push jack；
Blood characteristics collecting unit, including transmitting terminal and receiving terminal；
Push jack parameter determination unit, is connected with described blood characteristics collecting unit；And
Motion control unit；Methods described includes：
Blood-transmitted device is controlled to draw blood sample to be measured in the blood container of blood-transmitted device；
It is arranged on the blood characteristics collecting unit near blood container and launch detection signal to the blood sample in blood container, and
Receive the detection signal after the blood sample effect in blood container；
Push jack parameter is determined according to the detection signal after blood sample effect.
10. a kind of use push jack staining machine makes the method for blood smear it is characterised in that described push jack staining machine includes：
Blood-transmitted device, described blood-transmitted device includes blood container；
Push jack；
Blood characteristics collecting unit, including transmitting terminal and receiving terminal；
Push jack parameter determination unit, is connected with described blood characteristics collecting unit；And
Motion control unit；Methods described includes：
Blood-transmitted device is controlled to draw blood sample to be measured in the blood container of blood-transmitted device；
It is arranged on the blood characteristics collecting unit near blood container and launch detection signal to the blood sample in blood container, and
Receive the detection signal after the blood sample effect in blood container；
Push jack parameter determination unit determines push jack parameter according to the detection signal after blood sample effect；
Blood in blood container is discharged set amount on blood smear carrier；
The motion of the push jack state modulator push jack that motion control unit determines according to push jack parameter determination unit, thus complete blood apply
The making of piece.
11. methods as claimed in claim 10 are it is characterised in that described push jack parameter includes the amount of bleeding, diffusion time, push jack
Angle and push jack speed, motion control unit controls blood-transmitted device by blood container according to the amount of bleeding in push jack parameter
Interior blood discharges set amount on blood smear carrier.
12. methods as any one of claim 9-11 are it is characterised in that described blood characteristics collecting unit transmitting
Detection signal is optical, electromagnetic ripple or ultrasound wave, and the detection signal after described blood sample effect is blood sample to optical, electromagnetic ripple or ultrasound wave
Signal after effect.
A kind of 13. devices determining blood smear push jack parameter are it is characterised in that include：
Blood-transmitted device, for gathering blood sample to be measured, described blood-transmitted device includes blood container；
Blood characteristics collecting unit, it is arranged near blood container, and including transmitting terminal and receiving terminal, described transmitting terminal is to blood
Blood sample transmitting detection signal in liquid container, described receiving terminal is arranged in detection signal transmission path, receives and holds through blood
Detection signal after the blood sample effect received in device；
Push jack parameter determination unit, is connected with blood characteristics collecting unit, and the blood sample receiving the output of blood characteristics collecting unit is made
With after detection signal, according to blood sample effect after detection signal determine push jack parameter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210103396.3A CN103364236B (en) | 2012-04-10 | 2012-04-10 | Device and method for determining parameters of push pieces, push piece dyeing machine and method for manufacturing blood smear |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210103396.3A CN103364236B (en) | 2012-04-10 | 2012-04-10 | Device and method for determining parameters of push pieces, push piece dyeing machine and method for manufacturing blood smear |
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| CN103364236A CN103364236A (en) | 2013-10-23 |
| CN103364236B true CN103364236B (en) | 2017-02-08 |
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|---|---|---|---|---|
| WO2015139276A1 (en) * | 2014-03-20 | 2015-09-24 | 深圳迈瑞生物医疗电子股份有限公司 | Push piece dyeing machine and method for controlling push piece and device therefor |
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Application publication date: 20131023 Assignee: Shenzhen Mindray Animal Medical Technology Co.,Ltd. Assignor: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS Co.,Ltd. Contract record no.: X2022440020009 Denomination of invention: Device and method for determining push film parameters, push film dyeing machine and blood smear production method Granted publication date: 20170208 License type: Common License Record date: 20220804 |