CN101694431A - Automatic peripheral blood pushing device - Google Patents
Automatic peripheral blood pushing device Download PDFInfo
- Publication number
- CN101694431A CN101694431A CN200910235778A CN200910235778A CN101694431A CN 101694431 A CN101694431 A CN 101694431A CN 200910235778 A CN200910235778 A CN 200910235778A CN 200910235778 A CN200910235778 A CN 200910235778A CN 101694431 A CN101694431 A CN 101694431A
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- motor
- push jack
- blood
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- 210000005259 peripheral blood Anatomy 0.000 title claims abstract description 13
- 239000011886 peripheral blood Substances 0.000 title claims abstract description 13
- 230000001360 synchronised effect Effects 0.000 claims abstract description 16
- 239000004677 Nylon Substances 0.000 claims description 5
- 229920001778 nylon Polymers 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 abstract description 38
- 239000008280 blood Substances 0.000 abstract description 38
- 230000001133 acceleration Effects 0.000 abstract description 8
- 238000000034 method Methods 0.000 abstract description 4
- 230000008569 process Effects 0.000 abstract description 3
- 230000009471 action Effects 0.000 abstract description 2
- 239000011521 glass Substances 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002585 base Substances 0.000 description 24
- 230000033001 locomotion Effects 0.000 description 7
- 238000003745 diagnosis Methods 0.000 description 4
- 210000000265 leukocyte Anatomy 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000004159 blood analysis Methods 0.000 description 2
- 238000004820 blood count Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000000386 microscopy Methods 0.000 description 2
- 210000001616 monocyte Anatomy 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003979 eosinophil Anatomy 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N ferric oxide Chemical compound O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
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- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention relates to an automatic peripheral blood pushing device, which can achieve regular and standard blood smears by controlling parameters having directly affection on quality of the blood smears during a pushing process. Particularly, the automatic peripheral blood pushing device can control three degrees of freedom, utilizes a horizontal motor to control inclined included angle between a push slide and a glass slide, and utilizes a left motor to drive a synchronous belt pulley to complete blood pushing action, and adjusts speed and acceleration of the push slide by controlling rotation speed and acceleration of the left motor so as to control lengths of formed blood films. A clearance between the push slide and the horizontal glass slide is adjusted by utilizing an upper motor to drive a lead screw so as to control thicknesses of the formed blood films. Angle, speed and acceleration of the push slide, lengths of blood films and a clearance between the push slide and the glass slide can be adjusted by controlling running of the three motor, thereby manufacturing regular and stand blood smears with different thicknesses.
Description
Technical field
The invention belongs to medical instruments field, relate in particular to a kind of blood push jack preparation facilities of robotization.
Background technology
In recent years, along with being extensive use of of scientific-technical progress and computing machine, some self-reacting devices are introduced in the blood testing of clinical labororatory in a large number, make the laboratory simple more, quick, accurate to the processing of clinical samples, alleviate reviewer's working strength effectively, improved work efficiency.
Automated hematology analyzer application clinically at present is more extensive, and mostly this quasi-instrument is to obtain classification results by measuring the cell resistance variations.Experiment shows that blood analyser can not distinguish naivety, has a liking for acid, have a liking for alkali and monocyte, and the toxicity that more can not discern different pouring and erythroblast and neutrophil leucocyte changes.Some little granulocytes are taken as the cellule counting sometimes; some large lymphocytes, eosinophil, monocyte also are used as the maxicell counting; also have some platelet aggregations groups also to can be used as white blood cell count(WBC), particularly in white blood cell count(WBC) when normal or slightly higher or on the low side.Therefore, unusual blood sample occurs for some instrument detecting and must carry out the making of peripheral blood smear, carry out artificial microscopy, carry out making a definite diagnosis of disease according to the microscopy result then.Especially for the such major disease of similar tumour, can effectively avoid because the mistaken diagnosis that instrument error caused or fail to pinpoint a disease in diagnosis reduce the generation of malpractice, so the making of blood smear has also just become one of required skill of medical personnel.
According to the survey of domestic hospital, the whole nation has millions of blood films need carry out the leucocyte inspection every day.Still adopt manual method to make and make blood smear at present, efficiency ratio is lower.Medical personnel's carelessness or maloperation all will cause the making of blood film lack of standardization, can not effectively form monolayer and be used for check, perhaps cause clasmatosis owing to the strength of push jack is inhomogeneous, and subjective influence is bigger.In this case, if utilize robotization smear instrument to replace artificial treatment, not only can improve make efficiency, the reduction hand labor intensity of blood film greatly, and can eliminate the interference of subjective factor, guaranteed the blood film quality, can also improve the reliability of statistical test by increasing the check the number of check blood film, improve the accuracy rate of blood testing.
In addition, adopt computing machine to carry out mostly at the analysis of present blood and the differential count of haemocyte, therefore standardization, the workload when normalized blood smear can reduce blood analysis, improve the efficient of blood analysis, thereby the raising diagnosis efficiency has very great help to patient's timely treatment.
Summary of the invention
The object of the invention is to provide a kind of automatic peripheral blood pushing device, obtains standardization, standardized blood smear by the parameter that in the control push jack process blood film quality is had a direct impact.Make in the engineering at the blood film of reality, the variation in the gap between the angle of the speed of push jack, acceleration, push jack and push jack and the microslide can both exert an influence to the quality of blood smear, the present invention can judge the influence degree of every kind of parameter to the blood smear quality accurately, and by adjusting the blood smear quality of stability that these parameters guarantee the same sample of made.
With present existing smear device difference, this device has three degree of freedom, can regulate the speed acceleration of push jack angle, control push jack and the distance between control push jack and the microslide, avoid fully by rule of thumb the sample with different viscosityes being provided with in the existing apparatus shortcoming of identical push jack parameter, had more dirigibility and general applicability.
For achieving the above object, the technical solution adopted in the present invention is: a kind of automatic peripheral blood pushing device, push jack device have base plate, slide unit base and leading screw are installed on base plate.Be equiped with angle slide unit and microslide seat on the described slide unit base successively, microslide is placed on the microslide seat, adopts accurate angle slide unit can adjust angle and guarantees that microslide is in horizontality, effectively reduces the horizontal gradient error that mismachining tolerance causes microslide.
Described leading screw one end is connected with the last motor of vertical direction, the guide rail base plate links to each other with leading screw, adopt ball-screw that the rotation of stepper motor is converted into rectilinear motion, make the guide rail base plate to do upper and lower motion in vertical direction, this kind structure other devices relatively can be born bigger load, and structure is more compact.
Described guide rail base plate one end is equiped with left motor, and the other end is equiped with the synchronous pulley support, on the described synchronous pulley support synchronous pulley is installed, and described synchronous pulley links to each other with left machine shaft by being with synchronously.
Electric baseboard links to each other with synchronous band and is movably connected on by slide block in the guide rail of guide rail base plate, is equiped with horizontal motor and absolute encoder on the electric baseboard.Described horizontal machine shaft is fixedly connected with the push jack base, and push jack is fixed on the push jack base by the nylon briquetting.Described absolute encoder is connected with the round belt wheel, and described round belt wheel links to each other with the back rotating shaft of horizontal motor by round belt, and high-precision absolute encoder can realize controlling accurately the angle between push jack and the microslide, guarantees the standardization of blood smear.
Back rotating shaft at last motor and horizontal motor is connected with band-type brake respectively, and band-type brake is held tightly when motor reaches assigned address, and the blood smear quality of stability is guaranteed in vibrations when keeping the motor position can not move because of system and changing.
Be equiped with rubber blanket between push jack base and push jack, top nylon briquetting and following rubber blanket are pressed on push jack on the push jack base plate, guarantee that by friction force push jack does not slide under motion state.
The slanted angle of horizontal Electric Machine Control push jack and microslide among the present invention, left motor-driven synchronous pulley are finished the push jack action of blood, adjust the speed and the acceleration of push jack by controlling left rotating speed of motor and acceleration, and control forms the length of blood film.Adjust the gap of push jack and horizontal microslide by last motor-driven leading screw, reach the purpose of control blood film thickness.Can adjust the angle of push jack by the operation of controlling three motors, the speed of push jack and acceleration, the length of blood film, the standardization of various different-thickness, normalized blood film are realized producing in the gap between push jack and the microslide.
Description of drawings
Fig. 1 is an automatic peripheral blood pushing device perspective view of the present invention;
Fig. 2 is the push jack clamping place structural representation of automatic peripheral blood pushing device of the present invention.
Embodiment
The present invention is further detailed explanation below in conjunction with the drawings and specific embodiments.
As depicted in figs. 1 and 2, a kind of automatic peripheral blood pushing device, push jack device have base plate 1, slide unit base 2 and leading screw 3 are installed on base plate 1.Be equiped with angle slide unit 4 and microslide seat 5 on the described slide unit base 2 successively, microslide 23 is placed on the microslide seat 5, adopt accurate angle slide unit 4 can adjust angle and guarantee that microslide 23 is in horizontality, effectively reduce the horizontal gradient error that mismachining tolerance causes microslide 23.
Described leading screw 3 one ends are connected with the last motor 6 of vertical direction, guide rail base plate 7 links to each other with leading screw 3, adopt ball-screw that the rotation of stepper motor is converted into rectilinear motion, make guide rail base plate 7 to do upper and lower motion in vertical direction, this kind structure other devices relatively can be born bigger load, and structure is more compact.
Described guide rail base plate 7 one ends are equiped with left motor 8, and the other end is equiped with synchronous pulley support 9, on the described synchronous pulley support 9 synchronous pulley 10 are installed, and described synchronous pulley 10 is by linking to each other with the rotating shaft of left motor 8 with 11 synchronously.
Back rotating shaft at last motor 6 is connected with band-type brake 24, the back rotating shaft of horizontal motor 14 is connected with band-type brake 21, band- type brake 21,24 is held tightly when motor reaches assigned address, and the blood smear quality of stability is guaranteed in vibrations when keeping the motor position can not move because of system and changing.
Be equiped with rubber blanket 22 between push jack base 16 and push jack 17, top nylon briquetting 18 and following rubber blanket 22 are pressed on push jack 17 on the push jack base 16, guarantee that by friction force push jack 17 does not slide under the motion turntable.
In the practical operation, after circuit, each motor and microscope energising, microslide 23 is put on the microslide seat 5, and drips about 0.05ml of blood in mark position, on the host computer interface, configure the angle of push jack 17, push jack 17 and the gap of microslide 23 and the speed of push jack 17.Usually the angle of push jack 17 is between 30 °-45 °, and the speed of push jack 17 generally should be greater than 6cm/s.Host computer will come the angle operation of drive motor according to appointment to control circuit transmission corresponding instruction according to the parameter of setting this moment.By the angle that absolute encoder 15 calculating are walked, when reaching specified angle, horizontal motor 14 stops operating, and band-type brake 21 work that this moment is coupled avoid the push jack 17 and the angle of microslide 23 to change again.Helical pitch according to gap, angle and the step angle set and leading screw calculates the required umber of pulse of motor 6 operation respective distance automatically and sends to control circuit, motor 6 is held in band-type brake 24 work coupled after last motor 6 motions are finished tightly, horizontal then motor 14 carries out push jack according to the speed of setting, and so far finishes whole blood push jack and makes flow process.
The invention is not restricted to the foregoing description; to those skilled in the art, any conspicuous improvement that the above embodiment of the present invention is made or change can not exceed the embodiments of the invention that only illustrate by way of example and the protection domain of claims.
Claims (3)
1. automatic peripheral blood pushing device, it is characterized in that: described push jack device comprises base plate (1), is installed on slide unit base (2) and leading screw (3) on the base plate (1); Be equiped with angle slide unit (4) and microslide seat (5) on the described slide unit base (2) successively;
One end of described leading screw is connected with motor (6), guide rail base plate (7) is connected on the leading screw (3), described guide rail base plate (7) one ends are equiped with left motor (8), the other end is equiped with synchronous pulley support (9), synchronous pulley (10) is installed on the described synchronous pulley support (9), and described synchronous pulley (10) links to each other with left motor (8) by being with (11) synchronously;
Electric baseboard (12) links to each other with synchronous band (11) and is movably connected on by slide block (25) in the guide rail (13) of guide rail base plate (7);
Be equiped with horizontal motor (14) and absolute encoder (15) on the electric baseboard (12), the rotating shaft of described horizontal motor (14) is fixedly connected with push jack base (16), push jack (17) is fixed on the push jack base (16) by nylon briquetting (18), described absolute encoder (15) is connected with round belt wheel (19), and described round belt wheel (19) links to each other with the back rotating shaft of horizontal motor (14) by round belt (20).
2. a kind of automatic peripheral blood pushing device as claimed in claim 1 is characterized in that: the back rotating shaft of described upward motor (6) is connected with band-type brake (24), and the back rotating shaft of described horizontal motor (14) is connected with band-type brake (21).
3. a kind of automatic peripheral blood pushing device as claimed in claim 1 is characterized in that: be equiped with rubber blanket (22) between described push jack base (16) and the push jack (17).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910235778XA CN101694431B (en) | 2009-10-15 | 2009-10-15 | Automatic peripheral blood pushing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910235778XA CN101694431B (en) | 2009-10-15 | 2009-10-15 | Automatic peripheral blood pushing device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101694431A true CN101694431A (en) | 2010-04-14 |
| CN101694431B CN101694431B (en) | 2011-07-20 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200910235778XA Expired - Fee Related CN101694431B (en) | 2009-10-15 | 2009-10-15 | Automatic peripheral blood pushing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101694431B (en) |
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102620961A (en) * | 2012-03-21 | 2012-08-01 | 张震 | Preparation device for cell smear |
| CN102928270A (en) * | 2012-10-24 | 2013-02-13 | 马洪涛 | High speed coating head for automatically coating medicinal reagent |
| CN103364236A (en) * | 2012-04-10 | 2013-10-23 | 深圳迈瑞生物医疗电子股份有限公司 | Device and method for determining parameters of push pieces, push piece dyeing machine and method for manufacturing blood smear |
| CN104020024A (en) * | 2014-05-13 | 2014-09-03 | 贾印峰 | Multi-functional examination smear device |
| WO2015139276A1 (en) * | 2014-03-20 | 2015-09-24 | 深圳迈瑞生物医疗电子股份有限公司 | Push piece dyeing machine and method for controlling push piece and device therefor |
| CN105092323A (en) * | 2014-04-28 | 2015-11-25 | 深圳迈瑞生物医疗电子股份有限公司 | Method for adjusting blood film characteristics of blood smear pushed by push piece machine |
| CN105300759A (en) * | 2015-09-30 | 2016-02-03 | 爱威科技股份有限公司 | Scraper fixing device and blood smear pushing device |
| CN106353158A (en) * | 2016-08-29 | 2017-01-25 | 梅木精密工业(珠海)有限公司 | Automatic smear machine |
| CN106479863A (en) * | 2016-12-16 | 2017-03-08 | 中国科学院苏州生物医学工程技术研究所 | For making the pushing device of cell monolayer |
| CN106525803A (en) * | 2016-12-12 | 2017-03-22 | 中国科学院苏州生物医学工程技术研究所 | Biological imager |
| CN106885718A (en) * | 2015-12-15 | 2017-06-23 | 爱威科技股份有限公司 | Disposable blade system and blood film make instrument automatically |
| CN107132094A (en) * | 2017-05-25 | 2017-09-05 | 李企峥 | A kind of blood smear producing device |
| CN107192666A (en) * | 2017-05-16 | 2017-09-22 | 姜立敬 | A kind of intellectual medical examines apparatus |
| CN108333014A (en) * | 2017-01-17 | 2018-07-27 | 重庆迈德医疗器械有限公司 | A kind of automatic blood smear device |
| CN108535074A (en) * | 2018-07-13 | 2018-09-14 | 烟台毓璜顶医院 | A kind of blood smearing machine |
| CN110987574A (en) * | 2019-12-31 | 2020-04-10 | 保山中医药高等专科学校 | Dyeing device for making blood smear |
| CN113884352A (en) * | 2021-09-06 | 2022-01-04 | 国科赛赋河北医药技术有限公司 | Device capable of freely adjusting thickness of smear |
| CN114076699A (en) * | 2020-08-14 | 2022-02-22 | 爱威科技股份有限公司 | Blood push sheet manufacturing device |
| CN114486425A (en) * | 2021-12-31 | 2022-05-13 | 珠海森龙生物科技有限公司 | Continuous sheet pushing device of sheet pushing machine |
| CN116990099A (en) * | 2023-09-21 | 2023-11-03 | 佳木斯市中医医院 | Smear ware is used in medical science inspection |
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2009
- 2009-10-15 CN CN200910235778XA patent/CN101694431B/en not_active Expired - Fee Related
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|---|---|---|---|---|
| CN102620961A (en) * | 2012-03-21 | 2012-08-01 | 张震 | Preparation device for cell smear |
| CN103364236B (en) * | 2012-04-10 | 2017-02-08 | 深圳迈瑞生物医疗电子股份有限公司 | Device and method for determining parameters of push pieces, push piece dyeing machine and method for manufacturing blood smear |
| CN103364236A (en) * | 2012-04-10 | 2013-10-23 | 深圳迈瑞生物医疗电子股份有限公司 | Device and method for determining parameters of push pieces, push piece dyeing machine and method for manufacturing blood smear |
| CN102928270A (en) * | 2012-10-24 | 2013-02-13 | 马洪涛 | High speed coating head for automatically coating medicinal reagent |
| CN102928270B (en) * | 2012-10-24 | 2015-03-11 | 山东省产品质量检验研究院 | High speed coating head for automatically coating medicinal reagent |
| US11808676B2 (en) | 2014-03-20 | 2023-11-07 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Smear staining machine |
| WO2015139276A1 (en) * | 2014-03-20 | 2015-09-24 | 深圳迈瑞生物医疗电子股份有限公司 | Push piece dyeing machine and method for controlling push piece and device therefor |
| US11333586B2 (en) | 2014-03-20 | 2022-05-17 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Smear staining machine |
| US10648892B2 (en) | 2014-03-20 | 2020-05-12 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Smear staining machine |
| US9995660B2 (en) | 2014-03-20 | 2018-06-12 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Smear staining machine and smearing control method and device thereof |
| CN105092323B (en) * | 2014-04-28 | 2018-03-13 | 深圳迈瑞生物医疗电子股份有限公司 | A kind of blood film characterization method for adjusting sheet pushing machine and releasing blood film |
| CN105092323A (en) * | 2014-04-28 | 2015-11-25 | 深圳迈瑞生物医疗电子股份有限公司 | Method for adjusting blood film characteristics of blood smear pushed by push piece machine |
| CN104020024B (en) * | 2014-05-13 | 2016-07-06 | 贾佳霖 | Multifunctional inspection smear machine |
| CN104020024A (en) * | 2014-05-13 | 2014-09-03 | 贾印峰 | Multi-functional examination smear device |
| CN105300759A (en) * | 2015-09-30 | 2016-02-03 | 爱威科技股份有限公司 | Scraper fixing device and blood smear pushing device |
| CN105300759B (en) * | 2015-09-30 | 2018-12-11 | 爱威科技股份有限公司 | A kind of fixed device of scraping blade and blood film pushing device |
| CN106885718B (en) * | 2015-12-15 | 2020-04-17 | 爱威科技股份有限公司 | Disposable doctor blade system and automatic blood smear making instrument |
| CN106885718A (en) * | 2015-12-15 | 2017-06-23 | 爱威科技股份有限公司 | Disposable blade system and blood film make instrument automatically |
| CN106353158A (en) * | 2016-08-29 | 2017-01-25 | 梅木精密工业(珠海)有限公司 | Automatic smear machine |
| CN106525803A (en) * | 2016-12-12 | 2017-03-22 | 中国科学院苏州生物医学工程技术研究所 | Biological imager |
| CN106479863A (en) * | 2016-12-16 | 2017-03-08 | 中国科学院苏州生物医学工程技术研究所 | For making the pushing device of cell monolayer |
| CN106479863B (en) * | 2016-12-16 | 2019-08-27 | 中国科学院苏州生物医学工程技术研究所 | For making the pushing device of cell monolayer |
| CN108333014A (en) * | 2017-01-17 | 2018-07-27 | 重庆迈德医疗器械有限公司 | A kind of automatic blood smear device |
| CN107192666A (en) * | 2017-05-16 | 2017-09-22 | 姜立敬 | A kind of intellectual medical examines apparatus |
| CN107132094A (en) * | 2017-05-25 | 2017-09-05 | 李企峥 | A kind of blood smear producing device |
| CN108535074A (en) * | 2018-07-13 | 2018-09-14 | 烟台毓璜顶医院 | A kind of blood smearing machine |
| CN108535074B (en) * | 2018-07-13 | 2024-03-29 | 烟台毓璜顶医院 | Blood smear machine |
| CN110987574A (en) * | 2019-12-31 | 2020-04-10 | 保山中医药高等专科学校 | Dyeing device for making blood smear |
| CN114076699A (en) * | 2020-08-14 | 2022-02-22 | 爱威科技股份有限公司 | Blood push sheet manufacturing device |
| CN114076699B (en) * | 2020-08-14 | 2024-05-28 | 爱威科技股份有限公司 | Blood pushing sheet manufacturing device |
| CN113884352A (en) * | 2021-09-06 | 2022-01-04 | 国科赛赋河北医药技术有限公司 | Device capable of freely adjusting thickness of smear |
| CN113884352B (en) * | 2021-09-06 | 2024-02-09 | 国科赛赋河北医药技术有限公司 | Equipment capable of freely adjusting thickness of smear |
| CN114486425A (en) * | 2021-12-31 | 2022-05-13 | 珠海森龙生物科技有限公司 | Continuous sheet pushing device of sheet pushing machine |
| CN116990099B (en) * | 2023-09-21 | 2023-12-15 | 佳木斯市中医医院 | Smear ware is used in medical science inspection |
| CN116990099A (en) * | 2023-09-21 | 2023-11-03 | 佳木斯市中医医院 | Smear ware is used in medical science inspection |
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| Publication number | Publication date |
|---|---|
| CN101694431B (en) | 2011-07-20 |
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