Summary of the invention
The invention provides a kind of snow chrysanthemum cold tea and preparation method thereof, overcome the deficiency of above-mentioned prior art, it can effectively solve the problem of not avenging the chrysanthemum cold tea at present on the market.
One of technical scheme of the present invention realizes by following measure: a kind of snow chrysanthemum cold tea, obtain as follows: the first step, the score another name is got 0.2 part to 5 parts of chrysanthemum of snow, 0.1 part to 8 parts on safflower, 0.2 part to 2 parts of the tuber of dwarf lilyturf, 0.2 part to 5 parts of radix polygonati officinalis, 0.3 part to 10 parts in Radix Glycyrrhizae, 0.2 part to 2 parts of reed rhizome, 0.1 part to 5 parts of asparagus fern, 0.1 part to 5 parts of lophatherum gracile, 0.1 part to 1 part and 0.5 part to 5 parts sweetener of cogongrass rhizome by weight; Second step, the water of putting into parts by weight after the tuber of dwarf lilyturf, radix polygonati officinalis, Radix Glycyrrhizae, reed rhizome, asparagus fern, lophatherum gracile and cogongrass rhizome cleaned and be 53 parts to 98 parts is lixiviate 120 minutes to 150 minutes under 85 ℃ to the 95 ℃ conditions in temperature, will avenge then chrysanthemum, safflower clean the back temperature be 75 ℃ to 85 ℃ conditions descend to continue lixiviate obtained the extract I in 60 minutes to 120 minutes and carry after thing; In the 3rd step, with the extract I with carry the back thing and separate, to put into parts by weight be that 53 parts to 98 parts water is that lixiviate obtained the extract II in 60 minutes to 120 minutes under 75 ℃ to the 85 ℃ conditions in temperature carrying back thing then; The 4th step, obtain extract after merging extract I and extract II, extract is cooled to carries out coarse filtration after the room temperature and obtain avenging the thick tea juice of chrysanthemum, the sweetener that adds parts by weight in the thick tea juice of snow chrysanthemum and be 0.5 part to 5 parts is allocated, and carries out then obtaining avenging the chrysanthemum cold tea after essence filtered.
Two of technical scheme of the present invention realizes by following measure: a kind of preparation method who avenges the chrysanthemum cold tea, undertaken by following step: the first step, the score another name is got 0.2 part to 5 parts of chrysanthemum of snow, 0.1 part to 8 parts on safflower, 0.2 part to 2 parts of the tuber of dwarf lilyturf, 0.2 part to 5 parts of radix polygonati officinalis, 0.3 part to 10 parts in Radix Glycyrrhizae, 0.2 part to 2 parts of reed rhizome, 0.1 part to 5 parts of asparagus fern, 0.1 part to 5 parts of lophatherum gracile, 0.1 part to 1 part and 0.5 part to 5 parts sweetener of cogongrass rhizome by weight; Second step, the water of putting into parts by weight after the tuber of dwarf lilyturf, radix polygonati officinalis, Radix Glycyrrhizae, reed rhizome, asparagus fern, lophatherum gracile and cogongrass rhizome cleaned and be 53 parts to 98 parts is lixiviate 120 minutes to 150 minutes under 85 ℃ to the 95 ℃ conditions in temperature, will avenge then chrysanthemum, safflower clean the back temperature be 75 ℃ to 85 ℃ conditions descend to continue lixiviate obtained the extract I in 60 minutes to 120 minutes and carry after thing; In the 3rd step, with the extract I with carry the back thing and separate, to put into parts by weight be that 53 parts to 98 parts water is that lixiviate obtained the extract II in 60 minutes to 120 minutes under 75 ℃ to the 85 ℃ conditions in temperature carrying back thing then; The 4th step, obtain extract after merging extract I and extract II, extract is cooled to carries out coarse filtration after the room temperature and obtain avenging the thick tea juice of chrysanthemum, the sweetener that adds parts by weight in the thick tea juice of snow chrysanthemum and be 0.5 part to 5 parts is allocated, and carries out then obtaining avenging the chrysanthemum cold tea after essence filtered.
Be the further optimization and/or improvements to the foregoing invention technical scheme below:
Above-mentioned sweetener is white sugar and honey, and the parts by weight of the white sugar that adds in the snow chrysanthemum thick tea juice are that 0.2 part to 2 parts, the parts by weight of honey are 0.3 part to 3 parts.
Above-mentioned sweetener is xylitol.
Above-mentioned coarse filtration mode is for adopting the plate-frame filtering mode.
Above-mentioned smart filter mode is carried out the essence filter for adopting 0.45 micron membranes.
The snow chrysanthemum cold tea color and luster that obtains of invention is ruddy exquisitely carved, and long-term drinking can effectively play hyperlipemia, vascular hypertension patient and reduce and the effect of stable blood fat, blood pressure.
The specific embodiment
The present invention is not subjected to the restriction of following embodiment, can determine concrete embodiment according to technical scheme of the present invention and actual conditions.
Be further described below in conjunction with the present invention of embodiment:
Embodiment 1, this snow chrysanthemum cold tea obtains by following preparation method: the first step, and the score another name is got 0.2 part to 5 parts of chrysanthemum of snow, 0.1 part to 8 parts on safflower, 0.2 part to 2 parts of the tuber of dwarf lilyturf, 0.2 part to 5 parts of radix polygonati officinalis, 0.3 part to 10 parts in Radix Glycyrrhizae, 0.2 part to 2 parts of reed rhizome, 0.1 part to 5 parts of asparagus fern, 0.1 part to 5 parts of lophatherum gracile, 0.1 part to 1 part and 0.5 part to 5 parts sweetener of cogongrass rhizome by weight; Second step, the water of putting into parts by weight after the tuber of dwarf lilyturf, radix polygonati officinalis, Radix Glycyrrhizae, reed rhizome, asparagus fern, lophatherum gracile and cogongrass rhizome cleaned and be 53 parts to 98 parts is lixiviate 120 minutes to 150 minutes under 85 ℃ to the 95 ℃ conditions in temperature, will avenge then chrysanthemum, safflower clean the back temperature be 75 ℃ to 85 ℃ conditions descend to continue lixiviate obtained the extract I in 60 minutes to 120 minutes and carry after thing; In the 3rd step, with the extract I with carry the back thing and separate, to put into parts by weight be that 53 parts to 98 parts water is that lixiviate obtained the extract II in 60 minutes to 120 minutes under 75 ℃ to the 85 ℃ conditions in temperature carrying back thing then; The 4th step, obtain extract after merging extract I and extract II, extract is cooled to carries out coarse filtration after the room temperature and obtain avenging the thick tea juice of chrysanthemum, the sweetener that adds parts by weight in the thick tea juice of snow chrysanthemum and be 0.5 part to 5 parts is allocated, and carries out then obtaining avenging the chrysanthemum cold tea after essence filtered.
Embodiment 2, this snow chrysanthemum cold tea obtains by following preparation method: the first step, and score another name is got 0.1 part of 0.1 part of 0.2 part of 0.3 part in 0.2 part of 0.2 part of 0.1 part on 0.2 part of snow chrysanthemum or 5 parts, safflower or 8 parts, the tuber of dwarf lilyturf or 2 parts, radix polygonati officinalis or 5 parts, Radix Glycyrrhizae or 10 parts, reed rhizome or 2 parts, asparagus fern or 5 parts, lophatherum gracile or 5 parts, 0.1 part of cogongrass rhizome or 1 part and 0.5 part or 5 parts of sweeteners by weight; Second step, the water of putting into parts by weight after the tuber of dwarf lilyturf, radix polygonati officinalis, Radix Glycyrrhizae, reed rhizome, asparagus fern, lophatherum gracile and cogongrass rhizome cleaned and be 53 parts or 98 parts is lixiviate 120 minutes or 150 minutes under 85 ℃ or the 95 ℃ of conditions in temperature, will avenge then chrysanthemum, safflower clean the back temperature be 75 ℃ or 85 ℃ of conditions descend to continue lixiviate obtained the extract I in 60 minutes or 120 minutes and carry after thing; In the 3rd step, with the extract I with carry the back thing and separate, to put into parts by weight be that the water of 53 parts or 98 parts is that lixiviate obtained the extract II in 60 minutes or 120 minutes under 75 ℃ or the 85 ℃ of conditions in temperature carrying back thing then; The 4th step, obtain extract after merging extract I and extract II, extract is cooled to carries out coarse filtration after the room temperature and obtain avenging the thick tea juice of chrysanthemum, the sweetener that adds parts by weight in the thick tea juice of snow chrysanthemum and be 0.5 part or 5 parts is allocated, and carries out then obtaining avenging the chrysanthemum cold tea after essence filtered.
Embodiment 3, preferred as above-described embodiment, and sweetener is white sugar and honey, the parts by weight of the white sugar that adds in the thick tea juice of snow chrysanthemum are that 0.2 part to 2 parts, the parts by weight of honey are 0.3 part to 3 parts.
Embodiment 4, preferred as above-described embodiment, and sweetener is xylitol.
Embodiment 5, preferred as above-described embodiment, and the coarse filtration mode is for adopting the plate-frame filtering mode.
Embodiment 6, preferred as above-described embodiment, and smart filter mode is filtered for adopting 0.45 micron membranes to carry out essence.
One, the snow chrysanthemum cold tea that obtains according to the above embodiment of the present invention is to the influence of hyperlipemia mouse blood fat
1.1, medicine prepares
1.1.1, high lipoprotein emulsion can significantly cause the hyperlipidemia of rat, is the common dosage forms of setting up mouse hyperlipemia model at present.
The preparation of high lipoprotein emulsion: lard 40.0g places the 500ml beaker, heating and melting on the electric furnace, the back adds cholesterol 20.0g, add deoxysodium cholate 4.0g and propylthiouracil (PTU) 2.0g again, fully stir and add polysorbate40 .0ml, propane diols 40.0ml and distilled water 50.0ml constantly stirs, treat that propylthiouracil (PTU) fully dissolves after, be cooled to room temperature, add distilled water again and fully stir evenly to 200ml; Refrigerator is preserved, and dissolves 37 ℃ of water-baths during use.
, snow chrysanthemum cold tea extract: the proportional meter by 500ml is concentrated into 100ml, after will concentrating according to the snow chrysanthemum cold tea that the above embodiment of the present invention obtains, carry out freeze drying and obtain avenging chrysanthemum cold tea extract.
, grouping and administration
Animal grouping and administration: get 30 of mouse, be divided into 3 groups at random according to body weight: normal group, model group and experimental group;
Normal group every morning filling stomach only gives physiological saline 0.5m l/, and only give every mouse stomach, 2 weeks of successive administration with physiological saline by 0. 5m l/ afternoon;
Model group every morning filling stomach only gives high lipoprotein emulsion 0. 5m l/, and only give every mouse stomach, 2 weeks of successive administration with physiological saline by 0. 5m l/ afternoon;
Experimental group every morning filling stomach only gives high lipoprotein emulsion 0. 5m l/, and press 1. 5gs/kg to every mouse stomach, successive administration 2 weeks with snow chrysanthemum cold tea extract afternoon;
Weigh after the last administration, water 12h is can't help in fasting, and arteria carotis is got blood, and centrifuging and taking serum is measured serum total cholesterol, triglyceride, HDL-C, LDL-C with automatic biochemical analyzer.
, result and analysis
Serum total cholesterol, triglyceride, HDL-C, the LDL-C data of measuring see Table 1, and (n=12, x ± s); As can be seen from Table 1, model group is compared with normal group: serum total cholesterol, triglyceride and LDL-C obviously raise (P<0. 01), and HDL-C obviously reduces (P<0. 01), illustrate that model sets up successfully; Compare with model group, the experimental group serum total cholesterol reduces, and triglycerides reduces, HDL-C raises (P<0. 05), LDL-C reduces, and illustrates that avenging the chrysanthemum extract has tangible effect for reducing blood fat.
Two, the snow chrysanthemum cold tea that obtains according to the above embodiment of the present invention is to the influence of vascular hypertension patient blood fat
2.1, the grouping
Choose 100 volunteers that suffer from hyperlipemia, be divided into two groups at random, be respectively control group and experimental group, at viewing duration, control group and experimental group diet are consistent; Before the snow chrysanthemum cold tea of obtaining for the experimental group drink-service according to the above embodiment of the present invention, every volunteer of control group and experimental group is non-to measure every volunteer's blood pressure in early stage with the standard mercury gauge sphygmomanometer 3 times on the same day, and before measuring blood pressure complete rest 15min, measured value sees Table 2.
, experiment measuring
Control group: during the snow chrysanthemum cold tea of obtaining for the experimental group drink-service according to the above embodiment of the present invention, normal daily life, diet unanimity; Experimental group: normal daily life, diet unanimity, every snow chrysanthemum cold tea that volunteer's drink-service every day obtains according to the above embodiment of the present invention for 2 times, 500ml at every turn simultaneously.
During the snow chrysanthemum cold tea of obtaining for the experimental group drink-service according to the above embodiment of the present invention, measure the later stage blood pressure with standard mercury gauge sphygmomanometer control group and every volunteer of experimental group at twice weekly, and before the mensuration blood pressure complete rest 15min, measured value sees Table 2.Statistical method: the t check is adopted in the statistical procedures metering, and enumeration data adopts X
2
Check.
, result and analysis
As can be seen from Table 2, control group blood pressure change difference before and after the snow chrysanthemum cold tea of obtaining for the experimental group drink-service according to the above embodiment of the present invention is very little, and experimental group blood pressure change difference before and after the snow chrysanthemum cold tea that drink-service obtains according to the above embodiment of the present invention is bigger, and the blood pressure before the snow chrysanthemum cold tea that the blood pressure behind the snow chrysanthemum cold tea that drink-service obtains according to the above embodiment of the present invention obtains according to the above embodiment of the present invention than drink-service obviously reduces, therefore, the snow chrysanthemum cold tea that obtains according to the above embodiment of the present invention has the effect that reduces the hyperlipemia blood fat.
Ruddy exquisitely carved according to the snow chrysanthemum cold tea color and luster that the embodiment of the invention obtains, long-term drinking can effectively play hyperlipemia, vascular hypertension patient and reduce and the effect of stable blood fat, blood pressure.