CN103330658A - Skin care composition with functions of repairing damaged skin surface lipid film and relieving skin pressure - Google Patents
Skin care composition with functions of repairing damaged skin surface lipid film and relieving skin pressure Download PDFInfo
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- CN103330658A CN103330658A CN2013102557655A CN201310255765A CN103330658A CN 103330658 A CN103330658 A CN 103330658A CN 2013102557655 A CN2013102557655 A CN 2013102557655A CN 201310255765 A CN201310255765 A CN 201310255765A CN 103330658 A CN103330658 A CN 103330658A
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Abstract
The invention relates to a skin care composition with functions of repairing damaged skin surface lipid films and relieving skin pressure. The skin care composition is prepared from the following raw materials in percentage by weight: 5%-10% of oilseed rape sterol, 6%-18% of N-palmitoyl hydroxyproline spermaceti wax ester, 0.05%-0.5% of stearic acid, 0.5%-2.0% of bisabolol and the balance of tocopheryl acetate, wherein the weight percentage sum of the raw materials is 100%. The raw materials for preparing the skin care composition are selected from conventional raw materials in the field of skin care products. The skin care composition prepared through the scientific composition of the raw materials by an inventor has the advantages of effectively repairing damaged skin surface lipid films, increasing the moisture content in skins and reducing the irritability rate of the skins.
Description
Technical field
The present invention relates to a kind of impaired sebum film, the skin care compositions of the skin pressure of releiving and application on skin care field thereof of reparation that have.
Background technology
Skin say to keep soft bright and clean, mainly be because contain a certain amount of moisture in the skin histology, add that the oils and fats of the smegma in the skin and the perspiration of sweat gland secretion mix, form the very thin film of one deck at skin surface, medically be referred to as " sebum film ", its skin of can moistening can reduce the evaporation of moisture in the skin histology again greatly.In case sebum film is destroyed, not only water retaining function reduces, and also can make skin become dry, pruritus even cast off a skin.Reagency to factors such as weathers also weakens thereupon, very easily causes the skin redness, and is local general red even responsive phenomenon occurs.Occur pigementation especially easily, skin is pale inadequately.Can feel also after clean that skin is dry and astringent tight when healthy.Society along with environmental pollution constantly increases with the chemicals that contacts, is damaged the skin sebum film now, and various responsive skin and irritated skin constantly increase.
Summary of the invention
Technical problem to be solved by this invention provides a kind of impaired sebum film, the skin care compositions of the skin pressure of releiving and application on skin care field thereof of reparation that have.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of skin care compositions with the impaired sebum film of reparation, the skin pressure of releiving, described compositions is made by following raw materials by weight percent: campesterol 5-10%, N-palmityl hydroxyproline cetyl 6-18%, stearic acid 0.05-0.5%, bisabolol 0.5-2.0%, tocopherol acetas to 100%; Wherein, the percentage by weight sum of above-mentioned raw materials is 100%.
Produce synergism between above-mentioned each raw material, thereby can effectively repair sebum film, the skin pressure of releiving.
Each raw material effect brief introduction is as follows:
Tocopherol acetas: tocopherol acetas claims vitamin E again; prevent that in the body metabolic processes readily oxidizable substance such as unsaturated fatty acid is oxidized in cell membrane and the cell; thereby protect the complete of cell membrane and then prevent old and feeble effect, can keep genitals's normal function.Vitamin E has stronger reproducibility, can be used as antioxidant.As antioxidant in the body, eliminate interior free yl, reduce ultraviolet to the injury of human body.
Brassica campestris L (BRASSICACAMPESTRIS) sterol: be a kind of of plant sterol, skin is had very high permeability, can keep skin surface moisture content, promote skin metabolism, suppress scytitis, can prevent sunburn, skin aging, also have the effect of hair growth promoting, hair care.Can be used as the w/o type emulsifying agent, be used for the production of cream frost, have (auxilliary malleability is good, smooth does not glue), good endurance, the characteristics such as not perishable feel of using.Simultaneously, can also carry out cell signalling, promote the sebum film reparation.
N-palmityl hydroxyproline cetyl: N-palmityl hydroxyproline cetyl is close with the ceramide structure of matter that constitutes keratodermatitis; can penetrate into skin very soon; with the water combination in the horny layer; form a kind of network structure; pin moisture; play and prevent that moisture from distributing and outside stimulus is had the important function of safeguard function, bearing protection skin and moisten, moisture-keeping functions.Also there are many research reports to point out, can contain the external cream series products of ceramide by use, reach the purpose that prevents anaphylaxis dermatosis and the effect that suppresses the melanin brown patch.
Stearic acid: stearic acid is the free fatty in the sebum film, can suppress the growth of some invasive organism, and skin is had self-purification.Simultaneously, can also keep skin moisturizing, regulate the water oil balance of skin self, safeguard the normal formation of sebum film.
Bisabolol: the a-bisabolol is mainly used in skin care and the skin care cosmetics; the a-bisabolol as active component with the protection and the nursing allergic skin; can efficiently suppress IL-1 α comprehensively; PGE2; LTB4; multiple inflammatory mediators such as point such as TNF α, the stress state of the skin of effectively releiving.
The invention has the beneficial effects as follows: the main component of the tocopherol acetas among the present invention, Brassica campestris L (BRASSICACAMPESTRIS) sterol, N-palmityl hydroxyproline cetyl, stearic acid simulated skin horny layer molecular film, recombination classes is like the lipid bilayer of skin self rapidly, the efficient skin of repairing, improve the irritation ability of skin, reduce skin sensitivity, improve skin lock waterpower simultaneously.The neutral red bisabolol has antiinflammatory composition efficiently, can efficiently suppress multiple inflammatory mediators such as point such as IL-1 α, PGE2, LTB4, TNF α, the stress state of the skin of effectively releiving comprehensively.
The preferable percentage by weight of described each raw material of skin care compositions is:
Brassica campestris L (BRASSICACAMPESTRIS) sterol: 6-8%; N-palmityl hydroxyproline cetyl: 8-15%; Stearic acid: 0.1-0.4%; Bisabolol: 0.8-1.2%; Tocopherol acetas to 100%; Wherein, the percentage by weight sum of above-mentioned raw materials is 100%.
The optimum weight percentage ratio of described each raw material of skin care compositions is:
Brassica campestris L (BRASSICACAMPESTRIS) sterol: 7%; N-palmityl hydroxyproline cetyl: 10%; Stearic acid: 0.2%; Bisabolol: 1.0%; Tocopherol acetas 81.8%.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of application of skin care compositions on skin care field with the impaired sebum film of reparation, the skin pressure of releiving.Skin care compositions of the present invention can with the skin care field acceptable auxiliary, as water, glycerol equal solvent, emulsifying agents such as sorbitan stearate, polysorbate-60, thickening agents such as caprylic/capric triglyceride, Butyrospermum Parkii wet goods emollient and carbomer, HANSHENGJIAO are formed skin care formulation, and described skin care formulation can be applicable to skin care field.
According to use approach difference, skin care compositions of the present invention can prepare various external preparation, external facial cream, emulsion, essence, hand cream and massage cream etc.But be not limited to above-mentioned dosage form, can above-mentioned composition be made various external preparation by known method according to method known in the skin care field.
The preparation for repairing that the present invention makes is soft, non-stimulated.Its usage and consumption are as follows:
Method: after clean of every day, evenly smear the external preparation of an amount of the present invention's preparation on skin, each is once sooner or later; Also can be used as massage cream and use, use 1-2 time weekly;
Consumption: for nursing usefulness on ordinary days, smear preparation of the present invention in right amount and get final product according to individual demand.Use as massage cream, can increase consumption in right amount.
The invention has the beneficial effects as follows:
The conventional raw material of raw material selection skin care field of the present invention, the inventor carries out scientific composition to raw material, utilizes the synergism between each component, can effectively repair impaired sebum film, improves skin moisture content, reduces the skin allergy rate.
Description of drawings
To be the experimenter using blank sample and using repair cream skin moisture content curve chart after two hours, 7 days, 14 days, 21 days Fig. 1.
The specific embodiment
Below in conjunction with accompanying drawing principle of the present invention and feature are described, institute gives an actual example and only is used for explaining the present invention, is not for limiting scope of the present invention.
Embodiment 1:
A kind of skin care compositions with the impaired sebum film of reparation, the skin pressure of releiving, described compositions is made by following raw materials by weight percent: Brassica campestris L (BRASSICACAMPESTRIS) sterol: 5%; N-palmityl hydroxyproline cetyl: 10%; Stearic acid: 0.3%; Bisabolol: 2.0%; Tocopherol acetas 82.7%.
Embodiment 2:
A kind of skin care compositions with the impaired sebum film of reparation, the skin pressure of releiving, described compositions is made by following raw materials by weight percent: Brassica campestris L (BRASSICACAMPESTRIS) sterol: 7%; N-palmityl hydroxyproline cetyl: 14%; Stearic acid: 0.5%; Bisabolol: 1.5%; Tocopherol acetas 77.0%.
Embodiment 3:
A kind of skin care compositions with the impaired sebum film of reparation, the skin pressure of releiving, described compositions is made by following raw materials by weight percent: Brassica campestris L (BRASSICACAMPESTRIS) sterol: 8%; N-palmityl hydroxyproline cetyl: 18%; Stearic acid: 0.15%; Bisabolol: 0.5%; Tocopherol acetas 73.35%.
Embodiment 4:
A kind of skin care compositions with the impaired sebum film of reparation, the skin pressure of releiving, described compositions is made by following raw materials by weight percent: Brassica campestris L (BRASSICACAMPESTRIS) sterol: 10%; N-palmityl hydroxyproline cetyl: 6%; Stearic acid: 0.05%; Bisabolol: 1.0%; Tocopherol acetas 82.95%.
Below further specify the present invention by concrete test example.
Concrete test example 1 above-mentioned repair cream human skin patch
Material and method
1. tried thing: the preparation of repair cream:
A component: sorbitan stearate 1.5g, polysorbate-601.5g, caprylic/capric triglyceride 4g, glyceryl monostearate 2g, cetearyl alcohol 5g, shea butter 1g, polydimethylsiloxane 2g, Dormant oils 5.0g.
B component: glycerol 5g, butanediol 3g, xanthan gum 0.2g, deionized water 61.5g.
The skin care compositions 8g that C component: embodiment 1 obtains.
D component: floral perfume 0.1g, Methylisothiazolinone 0.2g.
Preparation method: the A component mixed be heated to 80 ℃, be incubated 20 minutes; The B component mixes and is heated to 80 ℃, is incubated 20 minutes.
The B component is added in the A component, and homogenizing stirs, and 80 ℃ are incubated 10 minutes.
Be cooled to 55 ℃, add the C component.
Be cooled to 45 ℃, add the D component.
Be cooled to 35 ℃, discharging, fill obtains repair cream.
2. negative control: blank
3. experimenter: totally 30 people, male 15 people, women 15 people at 21～50 years old age, meet the experimenter and volunteer inclusion criteria.
4. patch method: select qualified speckle examination device for use, with closed patch test method, to be tried the about 0.03g(mastic of thing) be applied in the speckle examination device, the external special adhesive tape sticks in the experimenter back, remove after 24 hours and tried thing, remove the back respectively and observed dermoreaction in 0.5,24,48 hour, record its result by dermoreaction grade scale in " cosmetics health standard " (version in 2007).Result of the test sees Table 1:
Table 1 human skin patch result
Human skin patch result shows: skin adverse reaction appears in 30 philtrums, 0 example; Illustrate that product of the present invention is safe to use.
Concrete test example 2 above-mentioned repair cream clinical effectiveness tests
1. experimenter: have dry and crackedly in various degree with skin, particularly facially 30 impaired people of sebum film such as dry peeling occurred and be subjects, wherein, women 15 examples, male 15 examples.Age, test lasted 14 days from 21～50 years old.
2. trial method: be coated with embodiment 1 above-mentioned repair cream every day outward 1～2 time, smear the face that the position is dry peeling.
With embodiment 1 above-mentioned repair cream be applied in skin after 2 hours skin become soft, prodding and itching feeling obviously reduces, and 24 examples (80%) are arranged, on probation after 7 days the skin urtication sense disappear, no skin effect phenomenon 28 examples (93%) are arranged.On probation skin does not have dry skin effect phenomenon after 14 days, and skin all recovers nature water profit state.
Test example 3: the evaluation of moisture-keeping efficacy
One, experimental principle
Human experimentation, the crowd forms test population by particular experiment, and test subject is used the variation of preparation skin care item front and back moisture of skin and moisture loss, determines the moisture-keeping efficacy of skin care item, thereby infers the effect that product is repaired impaired sebum film.
Two, experimental apparatus
Moisture content of skin test Corneometer CM825.
Three, experiment crowd and testing time
Have dry and crackedly in various degree with skin, particularly facially 30 impaired people of sebum film such as dry peeling occurred and be subjects, wherein, women 15 examples, male 15 examples.Age, test lasted 21 days from 21～50 years old.
Four, experimental technique
1. select the left and right cheek of experimenter cycle labeling successively;
2. use moisture content of skin test Corneometer CM825 that the cheek of not smearing repair cream is tested by the technical staff, average, be designated as blank value.
3. smear repair cream sample (with test example 1) at experimenter's cheek experiment position, blank is tried the zone and is not used any cosmetics.
4. the experimenter is using repair cream after two hours, 7 days, 14 days, 21 days continuously, uses moisture content of skin test Corneometer CM825 to measure 5 times by the technical staff, averages.
5. the statistics experimenter tests the numerical value that the position records at every turn, analyzes its skin moisture content Changing Pattern.
Five, experimental result
The result as shown in Figure 1, wherein to be the experimenter using blank sample and using repair cream skin moisture content curve chart after two hours, 7 days, 14 days, 21 days Fig. 1; As can be seen from Figure 1, the repair cream sample increases moisture content of skin, and moistening effect is remarkable, can effectively repair impaired sebum film.
The above only is preferred embodiment of the present invention, and is in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (4)
1. one kind has the skin care compositions of repairing impaired sebum film, the skin pressure of releiving, it is characterized in that, described compositions is made by following raw materials by weight percent: campesterol 5-10%, N-palmityl hydroxyproline cetyl 6-18%, stearic acid 0.05-0.5%, bisabolol 0.5-2.0%, tocopherol acetas to 100%; Wherein, the percentage by weight sum of above-mentioned raw materials is 100%.
2. according to claim 1 have a skin care compositions of repairing impaired sebum film, the skin pressure of releiving, it is characterized in that, described compositions is made by following raw materials by weight percent: campesterol 6-8%, N-palmityl hydroxyproline cetyl 8-15%, stearic acid 0.1-0.4%, bisabolol 0.8-1.2%, tocopherol acetas to 100%; Wherein, the percentage by weight sum of above-mentioned raw materials is 100%.
3. according to claim 1 have a skin care compositions of repairing impaired sebum film, the skin pressure of releiving, it is characterized in that, described compositions is mainly made by following raw materials by weight percent: campesterol 7%, N-palmityl hydroxyproline cetyl 10%, stearic acid 0.2%, bisabolol 1.0%, tocopherol acetas 81.8%.
4. one kind has the application of skin care compositions on skin care field of repairing impaired sebum film, the skin pressure of releiving.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201310255765.5A CN103330658B (en) | 2013-06-25 | 2013-06-25 | Skin care composition with functions of repairing damaged skin surface lipid film and relieving skin pressure |
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| CN201310255765.5A CN103330658B (en) | 2013-06-25 | 2013-06-25 | Skin care composition with functions of repairing damaged skin surface lipid film and relieving skin pressure |
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| CN103330658A true CN103330658A (en) | 2013-10-02 |
| CN103330658B CN103330658B (en) | 2015-06-17 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877102A (en) * | 2014-04-10 | 2014-06-25 | 上海紫邦生物医药有限公司 | Application of phytosterol or ester/bisabolol thereof in preparation of anti-inflammatory repairing medicine |
| CN103948532A (en) * | 2014-05-13 | 2014-07-30 | 张贺 | Cosmetic for moisturizing and soothing skin and preparation method of cosmetic |
| CN105496825A (en) * | 2016-01-20 | 2016-04-20 | 广州丹奇日用化工厂有限公司 | Cleansing cream capable of repairing damaged hydrolipidic film and preparation method thereof |
| CN109568231A (en) * | 2018-12-30 | 2019-04-05 | 广州瑞誉化工科技有限公司 | It is a kind of can Red blood streak dispelling skin composition and its preparation method and application |
| CN110448486A (en) * | 2019-08-14 | 2019-11-15 | 广州睿晞生化科技有限公司 | It is a kind of to repair the impaired essential oils of sebum film |
| CN110652477A (en) * | 2019-08-15 | 2020-01-07 | 广州欧盛化妆品有限公司 | Infant repair cream |
| CN111265461A (en) * | 2020-03-26 | 2020-06-12 | 上海绿瑞生物科技有限公司 | Water-oil dual-phase composition with allergy-relieving and repairing functions, preparation and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100286102A1 (en) * | 2004-11-22 | 2010-11-11 | Symrise Gmbh & Co. Kg | Formulations comprising ceramides and/or pseudoceramides and (alpha-)bisabolol for combating skin damage |
| US20120189684A1 (en) * | 2009-07-17 | 2012-07-26 | Reckitt Benckiser Healthcare International Limited | Skincare Compositions |
-
2013
- 2013-06-25 CN CN201310255765.5A patent/CN103330658B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100286102A1 (en) * | 2004-11-22 | 2010-11-11 | Symrise Gmbh & Co. Kg | Formulations comprising ceramides and/or pseudoceramides and (alpha-)bisabolol for combating skin damage |
| US20120189684A1 (en) * | 2009-07-17 | 2012-07-26 | Reckitt Benckiser Healthcare International Limited | Skincare Compositions |
Non-Patent Citations (2)
| Title |
|---|
| 佚名: ""SymRepair®153884德肤修"", 《百度空间，HTTP://HI.BAIDU.COM/ZG_CHEN/ITEM/35C3B8C6A5CFE16BF7C95D5A》 * |
| 佚名: ""SymRepair®153884德肤修"", 《百度空间，HTTP://HI.BAIDU.COM/ZG_CHEN/ITEM/35C3B8C6A5CFE16BF7C95D5A》, 16 December 2010 (2010-12-16) * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877102A (en) * | 2014-04-10 | 2014-06-25 | 上海紫邦生物医药有限公司 | Application of phytosterol or ester/bisabolol thereof in preparation of anti-inflammatory repairing medicine |
| CN103948532A (en) * | 2014-05-13 | 2014-07-30 | 张贺 | Cosmetic for moisturizing and soothing skin and preparation method of cosmetic |
| CN105496825A (en) * | 2016-01-20 | 2016-04-20 | 广州丹奇日用化工厂有限公司 | Cleansing cream capable of repairing damaged hydrolipidic film and preparation method thereof |
| CN109568231A (en) * | 2018-12-30 | 2019-04-05 | 广州瑞誉化工科技有限公司 | It is a kind of can Red blood streak dispelling skin composition and its preparation method and application |
| CN110448486A (en) * | 2019-08-14 | 2019-11-15 | 广州睿晞生化科技有限公司 | It is a kind of to repair the impaired essential oils of sebum film |
| CN110448486B (en) * | 2019-08-14 | 2021-06-11 | 广州睿晞生化科技有限公司 | Essential oil capable of repairing damaged sebum membrane |
| CN110652477A (en) * | 2019-08-15 | 2020-01-07 | 广州欧盛化妆品有限公司 | Infant repair cream |
| CN111265461A (en) * | 2020-03-26 | 2020-06-12 | 上海绿瑞生物科技有限公司 | Water-oil dual-phase composition with allergy-relieving and repairing functions, preparation and application thereof |
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| CN103330658B (en) | 2015-06-17 |
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