CN111265461A - Water-oil dual-phase composition with allergy-relieving and repairing functions, preparation and application thereof - Google Patents

Water-oil dual-phase composition with allergy-relieving and repairing functions, preparation and application thereof Download PDF

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CN111265461A
CN111265461A CN202010225448.9A CN202010225448A CN111265461A CN 111265461 A CN111265461 A CN 111265461A CN 202010225448 A CN202010225448 A CN 202010225448A CN 111265461 A CN111265461 A CN 111265461A
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water
oil
composition
extract
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王文扬
姜春鹏
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Shanghai Lvrui Biotechnology Co ltd
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Shanghai Lvrui Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/03Liquid compositions with two or more distinct layers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin

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Abstract

The invention provides a water-oil two-phase composition with a allergy-relieving repair function, and preparation and application thereof, wherein the composition comprises the following components in parts by weight: 15-40 parts of an emollient, 0.1-3 parts of 4-tert-butylcyclohexanol, 0.1-2 parts of bisabolol, 0.1-5 parts of oat extract, 0.1-5 parts of N-palmitoyl hydroxyproline cetyl ester, 2-15 parts of sunflower seed oil, 0.1-5 parts of campesterol, 0.05-0.3 part of menthol lactate, 0.1-0.5 part of an antioxidant, 30-70 parts of water, 0.5-5 parts of a humectant, 0.1-0.5 part of sodium chloride, 0.1-0.5 part of a bacteriostatic agent and 0.5-1.5 parts of a preservative. The mask can relieve the problems of skin sensitivity and discomfort caused by wearing the mask for a long time, helps to adjust the water-oil balance of the skin and repair the skin barrier, has fresh and cool skin feel and is not sticky, and has the advantages of long-acting moisture retention, long-acting moistening and the like.

Description

Water-oil dual-phase composition with allergy-relieving and repairing functions, preparation and application thereof
Technical Field
The invention belongs to the field of cosmetics, and particularly relates to a water-oil dual-phase composition with a allergy-relieving and repairing function, a preparation method and application thereof.
Background
During the outbreak of epidemic situation, in order to prevent the spread of virus, the wearing of the mask becomes a daily life habit, the wearing time is as long as 8 hours, and particularly, the wearing time of medical staff is as long as one whole day; under the influence of haze, the mask can be worn for a long time when the mask is used for outdoor work or going out; and some working people at special posts who need to wear the mask also need to wear the mask for a long time; due to the fact that the mask is worn for too long time, the skin problem of the face of the mask often occurs, and a series of skin problems such as pruritus, redness and contact dermatitis can be caused at the skin position where the mask is worn. The mask is mainly used for the following reasons that firstly, skin is in a relatively closed environment, and droplets generated by breathing and talking form a damp and hot environment under the mask to cause bacteria breeding; secondly, excessive water vapor is easily generated in the wearing process of the mask, if the time is long, the facial skin is affected by the water vapor in the closed state of the mask, overhydration occurs, and the skin is sensitive and possibly itchy, stabbing and red; thirdly, when the mask is worn, the user can continuously rub the mask and the skin when speaking and expressing, the skin is excessively hydrated and repeatedly rubbed and extruded, the skin barrier is damaged, and a series of skin problems such as pruritus, redness and contact dermatitis are generated, so that a mask face is formed. In daily care, a layer of protective film can be formed on the surface of skin by adopting the emollient oil, so that the emollient oil is helpful for supplementing skin lipid and resisting friction damage, and is a better solution, but most of the emollient oil is greasy in skin feel, strong in closure, not beneficial to skin breathing, and even causing the problem of acne or mouth closure; at present, no product specially developed for the problem of the mask face exists, but the problem causes skin troubles for people who wear the mask for a long time, and therefore, a nursing article capable of solving the problem of the mask face needs to be developed.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide a water-oil two-phase composition with a allergy-relieving repair function, a preparation method and application thereof.
The invention provides a water-oil dual-phase composition with a allergy-relieving and repairing function, which comprises the following components in parts by weight: 15-40 parts of an emollient, 0.1-3 parts of 4-tert-butylcyclohexanol, 0.1-2 parts of bisabolol, 0.1-5 parts of oat extract, 0.1-5 parts of N-palmitoyl hydroxyproline cetyl ester, 2-15 parts of sunflower seed oil, 0.1-5 parts of campesterol, 0.05-0.3 part of menthol lactate, 0.1-0.5 part of an antioxidant, 30-70 parts of water, 0.5-5 parts of a humectant, 0.1-0.5 part of sodium chloride, 0.1-0.5 part of a bacteriostatic agent and 0.5-1.5 parts of a preservative.
Preferably, the composition comprises, in parts by weight: 18-25 parts of emollient, 0.8-2 parts of 4-tert-butylcyclohexanol, 0.3-1 part of bisabolol, 0.5-3 parts of oat extract, 0.1-1 part of N-palmitoyl hydroxyproline cetyl ester, 5-12 parts of sunflower seed oil, 0.2-1 part of rape sterol, 0.1-0.2 part of menthol lactate, 0.1-0.4 part of antioxidant, 50-65 parts of water, 1-2.5 parts of humectant, 0.2-0.3 part of sodium chloride, 0.2-0.4 part of bacteriostatic agent and 0.8-1.3 parts of preservative.
Preferably, the emollient is one or a mixture of more than two of coconut oil alcohol-caprylate/caprate, isododecane, jojoba oil and squalane.
Preferably, the bacteriostatic agent comprises the following components in percentage by mass: 1-5% of Usnea barbata extract, 1-5% of patchouli leaf extract, 1-5% of cinnamon bark extract and the balance of water.
Preferably, the humectant is any one of a millettia extract and a tremella sporophore extract.
Preferably, the preservative is any one of phenoxyethanol, caprylyl hydroximic acid and hexanediol.
Preferably, the antioxidant is any one of tocopherol and rosemary leaf extract.
In a second aspect, the invention provides a preparation method of the above water-oil two-phase composition with a allergy-relieving and repairing function, comprising:
mixing emollient, cetyl N-palmitoyl hydroxyproline and campesterol, heating to completely dissolve to obtain a mixed solution, cooling to room temperature, adding 4-tert-butylcyclohexanol, bisabolol, sunflower seed oil, menthol lactate and antioxidant into the mixed solution, and stirring to obtain solution A;
mixing water, humectant, sodium chloride, bacteriostatic agent, antiseptic and herba Avenae Fatuae extract, and stirring to obtain solution B;
and filling the solution A and the solution B into the same packing material.
The third aspect of the invention provides an application of the water-oil dual-phase composition with the allergy-relieving and repairing functions, and the composition is applied to the protection of the face of a mask.
In the composition, the effect of relieving sensitivity is achieved under the cooperation of the bisabolol, the oat extract and the 4-tert-butylcyclohexanol, wherein the bisabolol is the main active ingredient in chamomile extract and can achieve the effect of instant relief by regulating cytokines (IL-1 α - α/IL-1 α 6, IL8), the NK-1 receptor is the key for triggering itchy skin sensation, the oat extract can be used as an NK-1 receptor synergist and can regulate the skin over-reaction, similar to the histamine resisting effect, generally, the burning sensation and the stinging sensation are heat receptors and are the result of over-expression of the TRPV1 receptor, and the 4-tert-butylcyclohexanol can selectively aim at the TRPV1 receptor to regulate the nerve sensory expression of the TRPV1 receptor on skin stimulation and readjust the balance in the skin.
In the composition, under the cooperative action of cetyl N-palmitoyl hydroxyproline, sunflower seed oil and rape sterol, the skin barrier can be repaired. Generally three key lipids of the lipid bilayer: ceramide, free fatty acid, cholesterol; the cetyl ester of N-palmitoyl hydroxyproline has a structure similar to ceramide, the sunflower seed oil contains rich free fatty acid, and the brassinosteroids have a cholesterol-like structure, so that a bionic sebum environment can be created by compounding the three raw materials, and the skin barrier repair is facilitated.
The bacteriostatic agent in the composition is preferably a compound of usnea barbata extract, patchouli leaf extract and cinnamon bark extract, and has bacteriostatic action.
In the composition, the moisturizing agent is preferably a millettia extract which is rich in glucoside, wherein the glucoside is a key component of the millettia capable of surviving in Africa under the conditions of long-term high temperature, drought, water shortage and high-intensity UV radiation, and has the effect of long-acting moisturizing.
Compared with the prior art, the invention has at least one of the following beneficial effects:
1. the raw materials adopted by the composition are green and environment-friendly; the mask can relieve the problems of skin sensitivity and discomfort caused by wearing the mask for a long time, helps to adjust the water-oil balance of the skin, repairs the skin barrier, and has the advantages of long-acting moisture retention, long-acting moistening and the like. The composition does not need to add an emulsifier, and the oil can be atomized into small droplets by pump head shearing, so that the skin can absorb more easily.
2. The composition is prepared into two layers when standing, namely an upper oil phase and a lower water phase, and is shaken and uniformly mixed when in use, and can be atomized by using a spray pump head to form tiny droplets which are sprayed on the surface of the skin to form a light and breathable film on the surface of the skin, so that the damage caused by friction is reduced, the skin barrier is repaired, and the skin problems of pruritus, redness and the like are effectively relieved. The product is convenient to use when applied to face care mask, and can be applied after being sprayed.
3. The composition disclosed by the invention is simple in preparation process, low in energy consumption, green and environment-friendly (high-temperature homogenizing emulsification is not needed and the like).
Detailed Description
The present invention will be described in detail with reference to specific examples. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that variations and modifications can be made by persons skilled in the art without departing from the spirit of the invention. All falling within the scope of the present invention.
Example 1
The embodiment provides a water-oil dual-phase composition with a allergy-relieving and repairing function, which comprises the following components in parts by weight: 15 parts of emollient, 0.1 part of 4-tert-butylcyclohexanol, 0.1 part of bisabolol, 0.1 part of oat extract, 0.1 part of cetyl N-palmitoyl hydroxyproline, 2 parts of sunflower seed oil, 0.1 part of campesterol, 0.05 part of menthol lactate, 0.1 part of antioxidant, 30 parts of water, 0.5 part of humectant, 0.1 part of sodium chloride, 0.1 part of bacteriostatic agent and 0.5 part of preservative.
The oat extract can be selected from SK-Calmin Dermatosu, which is a commercially available product, and can be purchased from Meilelian Biotech, Fuzhou, Inc.
The emollient may be selected from coconut oil alcohol-caprylate/caprate.
The antioxidant can be tocopherol.
The antiseptic can be phenoxyethanol.
The humectant can be Artocarpus heterophyllus extract. The extract of Artocarpus heterophyllus contains abundant glucoside, is a key component of Artocarpus heterophyllus capable of surviving in Africa under long-term high temperature, drought, water shortage and high-intensity UV radiation, and has long-acting moisture retention effect. The extract of Artocarpus heterophyllus may be obtained from a commercial product available under the tradename DERMOISTIN FURUSHU, available from MEILOVA Biotech, FOUNZHOU.
The bacteriostatic agent comprises the following components, by mass, 1% of Usnea barbata extract, 1% of patchouli leaf extract, 1% of cinnamon bark extract and the balance of water.
The composition can be prepared by the following method, and the specific steps are as follows:
(1) mixing emollient, cetyl N-palmitoyl hydroxyproline and campesterol, heating to dissolve completely, cooling to room temperature, adding 4-tert-butylcyclohexanol, bisabolol, sunflower seed oil, menthol lactate and antioxidant, and stirring to obtain solution A;
(2) mixing water, humectant, sodium chloride, bacteriostatic agent, antiseptic, and herba Avenae Fatuae extract, and stirring to obtain solution B;
(3) and sequentially filling the solution A and the solution B into the same packaging material.
In the specific implementation of the above embodiment, the composition is applied to the protection of the face of a mask, and before the use, the composition is allowed to stand to form two layers, namely an upper oil phase and a lower water phase; when in use, the oil phase at the upper layer and the water phase at the lower layer are shaken and mixed, and the composition can be atomized by using a spray pump head to form tiny droplets which are sprayed on the surface of the skin to form a light and breathable film on the surface of the skin.
Example 2
The embodiment provides a water-oil dual-phase composition with a allergy-relieving and repairing function, which comprises the following components in parts by weight: 40 parts of an emollient, 3 parts of 4-tert-butylcyclohexanol, 2 parts of bisabolol, 5 parts of an oat extract, 5 parts of cetyl N-palmitoyl hydroxyproline, 15 parts of sunflower seed oil, 5 parts of brassinosteroids, 0.3 part of menthol lactate, 0.5 part of an antioxidant, 70 parts of water, 5 parts of a humectant, 0.5 part of sodium chloride, 0.5 part of a bacteriostatic agent and 1.5 parts of a preservative.
The oat extract can be selected from SK-Calmin Dermatosu, which is a commercially available product, and can be purchased from Meilelian Biotech, Fuzhou, Inc.
The emollient is isododecane.
The antioxidant can be rosemary leaf extract.
The humectant can be Tremella fuciformis berk extract.
The preservative can be caprylyl hydroximic acid.
The bacteriostatic agent comprises, by mass, 5% of Usnea barbata extract, 5% of patchouli leaf extract, 5% of cinnamon bark extract and the balance of water.
The composition can be prepared by the following method, and the specific steps are as follows:
(1) mixing emollient, cetyl N-palmitoyl hydroxyproline and campesterol, heating to dissolve completely, cooling to room temperature, adding 4-tert-butylcyclohexanol, bisabolol, sunflower seed oil, menthol lactate and antioxidant, and stirring to obtain solution A;
(2) mixing water, humectant, sodium chloride, bacteriostatic agent, antiseptic, and herba Avenae Fatuae extract, and stirring to obtain solution B;
(3) and sequentially filling the solution A and the solution B into the same packaging material.
In the specific implementation of the above embodiment, the composition is applied to the protection of the face of a mask, and before the use, the composition is allowed to stand to form two layers, namely an upper oil phase and a lower water phase; when in use, the oil phase at the upper layer and the water phase at the lower layer are shaken and mixed, and the composition can be atomized by using a spray pump head to form tiny droplets which are sprayed on the surface of the skin to form a light and breathable film on the surface of the skin.
Example 3
The embodiment provides a water-oil dual-phase composition with a allergy-relieving and repairing function, which comprises the following components in parts by weight: 27 parts of emollient, 1.6 parts of 4-tert-butylcyclohexanol, 1.1 parts of bisabolol, 2.5 parts of oat extract, 2.5 parts of cetyl N-palmitoyl hydroxyproline, 8 parts of sunflower seed oil, 0.2 part of menthol lactate, 2.5 parts of campesterol, 0.25 part of antioxidant, 55 parts of water, 3 parts of humectant, 0.3 part of sodium chloride, 0.25 part of bacteriostatic agent and 1 part of preservative.
The oat extract can be selected from SK-Calmin Dermatosu, which is a commercially available product, and can be purchased from Meilelian Biotech, Fuzhou, Inc.
The emollient is selected from mixture of jojoba oil and squalane.
The antioxidant can be rosemary leaf extract.
The humectant can be selected from extract of Artocarpus heterophyllus.
The antiseptic can be selected from hexanediol.
The bacteriostatic agent comprises, by mass, 2.8% of Usnea barbata extract, 3% of patchouli leaf extract, 3% of cinnamon bark extract and the balance of water.
The composition can be prepared by the following method, and the specific steps are as follows:
(1) mixing emollient, cetyl N-palmitoyl hydroxyproline and campesterol, heating to dissolve completely, cooling to room temperature, adding 4-tert-butylcyclohexanol, bisabolol, sunflower seed oil, menthol lactate and antioxidant, and stirring to obtain solution A;
(2) mixing water, humectant, sodium chloride, bacteriostatic agent, antiseptic, and herba Avenae Fatuae extract, and stirring to obtain solution B;
(3) and sequentially filling the A and the B into the same packaging material.
In the specific implementation of the above embodiment, the composition is applied to the protection of the face of a mask, and before the use, the composition is allowed to stand to form two layers, namely an upper oil phase and a lower water phase; when in use, the oil phase at the upper layer and the water phase at the lower layer are shaken and mixed, and the composition can be atomized by using a spray pump head to form tiny droplets which are sprayed on the surface of the skin to form a light and breathable film on the surface of the skin.
Example 4
The embodiment provides a water-oil dual-phase composition with a allergy-relieving and repairing function, which comprises the following components in parts by weight: 18 parts of emollient, 0.8 part of 4-tert-butylcyclohexanol, 0.3 part of bisabolol, 0.5 part of oat extract, 0.1 part of cetyl N-palmitoyl hydroxyproline, 5 parts of sunflower seed oil, 0.1 part of menthol lactate, 0.2 part of campesterol, 0.1 part of antioxidant, 50 parts of water, 1 part of humectant, 0.25 part of sodium chloride, 0.2 part of bacteriostatic agent and 0.8 part of preservative.
The oat extract can be selected from SK-Calmin Dermatosu, which is a commercially available product, and can be purchased from Meilelian Biotech, Fuzhou, Inc.
The emollient is squalane.
The antioxidant can be tocopherol.
The humectant can be selected from extract of Artocarpus heterophyllus.
The antiseptic can be phenoxyethanol.
The bacteriostatic agent comprises, by mass, 5% of Usnea barbata extract, 5% of patchouli leaf extract, 5% of cinnamon bark extract and the balance of water.
The composition can be prepared by the following method, and the specific steps are as follows:
(1) mixing emollient, cetyl N-palmitoyl hydroxyproline and campesterol, heating to dissolve completely, cooling to room temperature, adding 4-tert-butylcyclohexanol, bisabolol, sunflower seed oil, menthol lactate and antioxidant, and stirring to obtain solution A;
(2) mixing water, humectant, sodium chloride, bacteriostatic agent, antiseptic, and herba Avenae Fatuae extract, and stirring to obtain solution B;
(3) and sequentially filling the solution A and the solution B into the same packaging material.
In the specific implementation of the above embodiment, the composition is applied to the protection of the face of a mask, and before the use, the composition is allowed to stand to form two layers, namely an upper oil phase and a lower water phase; when in use, the oil phase at the upper layer and the water phase at the lower layer are shaken and mixed, and the composition can be atomized by using a spray pump head to form tiny droplets which are sprayed on the surface of the skin to form a light and breathable film on the surface of the skin.
Example 5
The embodiment provides a water-oil dual-phase composition with a allergy-relieving and repairing function, which comprises the following components in parts by weight: 25 parts of emollient, 2 parts of 4-tert-butyl cyclohexanol, 1 part of bisabolol, 3 parts of oat extract, 1 part of cetyl N-palmitoyl hydroxyproline, 12 parts of sunflower seed oil, 0.2 part of menthol lactate, 1 part of campesterol, 0.4 part of antioxidant, 65 parts of water, 2.5 parts of humectant, 0.4 part of sodium chloride, 0.4 part of bacteriostatic agent and 1.3 parts of preservative.
The oat extract can be selected from SK-Calmin Dermatosu, which is a commercially available product, and can be purchased from Meilelian Biotech, Fuzhou, Inc.
The emollient may be selected from a mixture of coco-caprylate/caprate and isododecane.
The humectant can be Tremella fuciformis berk extract.
The antioxidant can be rosemary leaf extract.
The preservative can be caprylyl hydroximic acid.
The bacteriostatic agent comprises the following components, by mass, 1% of Usnea barbata extract, 1% of patchouli leaf extract, 1% of cinnamon bark extract and the balance of water.
The composition can be prepared by the following method, and the specific steps are as follows:
(1) mixing emollient, cetyl N-palmitoyl hydroxyproline and campesterol, heating to dissolve completely, cooling to room temperature, adding 4-tert-butylcyclohexanol, bisabolol, sunflower seed oil, menthol lactate and antioxidant, and stirring to obtain solution A;
(2) mixing water, humectant, sodium chloride, bacteriostatic agent, antiseptic, and herba Avenae Fatuae extract, and stirring to obtain solution B;
(3) and sequentially filling the solution A and the solution B into the same packaging material.
In the specific implementation of the above embodiment, the composition is applied to the protection of the face of a mask, and before the use, the composition is allowed to stand to form two layers, namely an upper oil phase and a lower water phase; when in use, the oil phase at the upper layer and the water phase at the lower layer are shaken and mixed, and the composition can be atomized by using a spray pump head to form tiny droplets which are sprayed on the surface of the skin to form a light and breathable film on the surface of the skin.
Example 6
The embodiment provides a water-oil dual-phase composition with a allergy-relieving and repairing function, which comprises the following components in parts by weight: 20 parts of coconut oil alcohol-caprylic acid ester/caprate, 1 part of 4-tert-butyl cyclohexanol, 0.5 part of bisabolol, 1 part of oat extract, 0.5 part of N-palmitoyl hydroxyproline cetyl ester, 10 parts of sunflower seed oil, 0.15 part of menthol lactate, 0.5 part of rape sterol, 0.2 part of antioxidant, 2 parts of humectant, 0.3 part of sodium chloride, 0.3 part of bacteriostatic agent, 1 part of preservative and 63 parts of water.
The oat extract can be selected from SK-Calmin Dermatosu, which is a commercially available product, and can be purchased from Meilelian Biotech, Fuzhou, Inc.
The emollient may be selected from coconut oil alcohol-caprylate/caprate.
The humectant can be selected from extract of Artocarpus heterophyllus.
The antioxidant can be tocopherol.
The antiseptic can be phenoxyethanol
The bacteriostatic agent comprises, by mass, 2.8% of Usnea barbata extract, 3% of patchouli leaf extract, 3% of cinnamon bark extract and the balance of water.
The composition can be prepared by the following method, and the specific steps are as follows:
(1) mixing emollient, cetyl N-palmitoyl hydroxyproline and campesterol, heating to dissolve completely, cooling to room temperature, adding 4-tert-butylcyclohexanol, bisabolol, sunflower seed oil, menthol lactate and antioxidant, and stirring to obtain solution A;
(2) mixing water, humectant, sodium chloride, bacteriostatic agent, antiseptic, and herba Avenae Fatuae extract, and stirring to obtain solution B;
(3) and sequentially filling the solution A and the solution B into the same packaging material.
In the specific implementation of the above embodiment, the composition is applied to the protection of the face of a mask, and before the use, the composition is allowed to stand to form two layers, namely an upper oil phase and a lower water phase; when in use, the oil phase at the upper layer and the water phase at the lower layer are shaken and mixed, and the composition can be atomized by using a spray pump head to form tiny droplets which are sprayed on the surface of the skin to form a light and breathable film on the surface of the skin.
Evaluation of Performance
1.5 volunteers who were worn on the mask for more than 6 hours per day were selected, and the sample was evaluated after a certain period of time using the two-phase water-oil composition having the allergy-relieving and repairing functions obtained in example 6.
The results obtained were as follows:
TABLE 1 evaluation of the use of the Water-oil two-phase with soothing and repairing function obtained in example 6
Figure BDA0002427485280000091
Wherein volunteer 1 also used the water-oil biphasic composition with soothing and repairing function of examples 1-5, the results are given in the following table:
TABLE 2 evaluation of the use of the compositions of examples 1-5 for the water-oil dual phase with soothing and repairing functions
Example number Skin state after a period of use
Example 1 The skin is moist and the pruritus is relieved to a certain extent, and occasionally some skin peels
Example 2 The skin is moist, the friction pain is relieved, and the pruritus is relieved to a certain degree
Example 3 Moist skin, no prickle, itching with a certain degree of relief, slight desquamation
Example 4 The skin is moist and does not peel any more, the friction pain is relieved, and the pruritus is relieved to a certain extent
Example 5 The skin is moist, no longer desquamation, and the pruritus is relieved to a certain extent
The foregoing description of specific embodiments of the present invention has been presented. It is to be understood that the present invention is not limited to the specific embodiments described above, and that various changes and modifications may be made by one skilled in the art within the scope of the appended claims without departing from the spirit of the invention.

Claims (9)

1. A water-oil two-phase composition with a allergy-relieving and repairing function is characterized in that: the composition comprises the following components in parts by weight: 15-40 parts of an emollient, 0.1-3 parts of 4-tert-butylcyclohexanol, 0.1-2 parts of bisabolol, 0.1-5 parts of oat extract, 0.1-5 parts of N-palmitoyl hydroxyproline cetyl ester, 2-15 parts of sunflower seed oil, 0.1-5 parts of campesterol, 0.05-0.3 part of menthol lactate, 0.1-0.5 part of an antioxidant, 30-70 parts of water, 0.5-5 parts of a humectant, 0.1-0.5 part of sodium chloride, 0.1-0.5 part of a bacteriostatic agent and 0.5-1.5 parts of a preservative.
2. The water-oil dual-phase composition with the allergy relieving and repairing functions as claimed in claim 1, wherein: the composition comprises the following components in parts by weight: 18-25 parts of emollient, 0.8-2 parts of 4-tert-butylcyclohexanol, 0.3-1 part of bisabolol, 0.5-3 parts of oat extract, 0.1-1 part of N-palmitoyl hydroxyproline cetyl ester, 5-12 parts of sunflower seed oil, 0.2-1 part of rape sterol, 0.1-0.2 part of menthol lactate, 0.1-0.4 part of antioxidant, 50-65 parts of water, 1-2.5 parts of humectant, 0.2-0.3 part of sodium chloride, 0.2-0.4 part of bacteriostatic agent and 0.8-1.3 parts of preservative.
3. The composition with the water-oil dual phase and the allergy relieving and repairing functions as claimed in claim 1 or 2, wherein: the emollient is one or more of coconut oil alcohol-caprylate/caprate, isododecane, jojoba oil and squalane.
4. The composition with the water-oil dual phase and the allergy relieving and repairing functions as claimed in claim 1 or 2, wherein: the bacteriostatic agent comprises the following components in percentage by mass: 1-5% of Usnea barbata extract, 1-5% of patchouli leaf extract, 1-5% of cinnamon bark extract and the balance of water.
5. The composition with the water-oil dual phase and the allergy relieving and repairing functions as claimed in claim 1 or 2, wherein: the humectant is any one of extract of Mimusops tauschii and extract of Tremella fuciformis berk.
6. The composition with the water-oil dual phase and the allergy relieving and repairing functions as claimed in claim 1 or 2, wherein: the preservative is any one of phenoxyethanol, caprylyl hydroximic acid and hexanediol.
7. The composition with the water-oil dual phase and the allergy relieving and repairing functions as claimed in claim 1 or 2, wherein: the antioxidant is any one of tocopherol and rosemary leaf extract.
8. A method for preparing the water-oil dual-phase composition with the allergy-relieving and repairing functions, which is disclosed by any one of claims 1 to 7, and is characterized in that: the method comprises the following steps:
mixing emollient, cetyl N-palmitoyl hydroxyproline and campesterol, heating to completely dissolve to obtain a mixed solution, cooling to room temperature, adding 4-tert-butylcyclohexanol, bisabolol, sunflower seed oil, menthol lactate and antioxidant into the mixed solution, and stirring to obtain solution A;
mixing water, humectant, sodium chloride, bacteriostatic agent, antiseptic and herba Avenae Fatuae extract, and stirring to obtain solution B;
and filling the solution A and the solution B into the same packing material.
9. Use of a water-oil biphasic composition with a soothing and healing function, characterized in that a composition according to any one of claims 1-7 is used in protection against a breathing mask face.
CN202010225448.9A 2020-03-26 2020-03-26 Water-oil dual-phase composition with allergy-relieving and repairing functions, preparation and application thereof Pending CN111265461A (en)

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CN111588687A (en) * 2020-07-07 2020-08-28 上海新高姿化妆品有限公司 Water-oil bin-separated moisturizing and relieving composition, preparation method and application
CN112137931A (en) * 2020-10-21 2020-12-29 上海科颜生物科技有限公司 High-efficiency composition for relieving sensitive skin and application thereof
CN112773738A (en) * 2021-02-23 2021-05-11 上海美浮特生物科技有限公司 Moisturizing and relieving composition, preparation method thereof, skin care product and application

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CN103330658A (en) * 2013-06-25 2013-10-02 烟台新时代健康产业日化有限公司 Skin care composition with functions of repairing damaged skin surface lipid film and relieving skin pressure
CN110237014A (en) * 2019-07-04 2019-09-17 上海绿瑞生物科技有限公司 A kind of water oil dual phase composition and preparation method thereof with the effect of releiving
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CN111588687A (en) * 2020-07-07 2020-08-28 上海新高姿化妆品有限公司 Water-oil bin-separated moisturizing and relieving composition, preparation method and application
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CN112137931A (en) * 2020-10-21 2020-12-29 上海科颜生物科技有限公司 High-efficiency composition for relieving sensitive skin and application thereof
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CN112773738A (en) * 2021-02-23 2021-05-11 上海美浮特生物科技有限公司 Moisturizing and relieving composition, preparation method thereof, skin care product and application

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