CN103319506A - 一种[Cu2(L3)2]的原位合成方法 - Google Patents
一种[Cu2(L3)2]的原位合成方法 Download PDFInfo
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- CN103319506A CN103319506A CN2013102814141A CN201310281414A CN103319506A CN 103319506 A CN103319506 A CN 103319506A CN 2013102814141 A CN2013102814141 A CN 2013102814141A CN 201310281414 A CN201310281414 A CN 201310281414A CN 103319506 A CN103319506 A CN 103319506A
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- 238000011065 in-situ storage Methods 0.000 title claims abstract description 9
- 238000001308 synthesis method Methods 0.000 title abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 30
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims abstract description 15
- XTVVROIMIGLXTD-UHFFFAOYSA-N copper(II) nitrate Chemical compound [Cu+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O XTVVROIMIGLXTD-UHFFFAOYSA-N 0.000 claims abstract description 13
- 238000006243 chemical reaction Methods 0.000 claims abstract description 9
- 238000005406 washing Methods 0.000 claims abstract description 5
- 238000010189 synthetic method Methods 0.000 claims description 5
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical group FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 claims description 4
- 238000000034 method Methods 0.000 abstract description 8
- 239000002904 solvent Substances 0.000 abstract description 3
- -1 polytetrafluoroethylene Polymers 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 238000001816 cooling Methods 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000011259 mixed solution Substances 0.000 abstract 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 abstract 1
- 239000004810 polytetrafluoroethylene Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- AULWPXHFRBLPAE-UHFFFAOYSA-N 6-chloropyridine Chemical compound ClC1=C=CC=C[N]1 AULWPXHFRBLPAE-UHFFFAOYSA-N 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
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CN201310281414.1A CN103319506B (zh) | 2013-07-05 | 2013-07-05 | 一种[Cu2(L3)2]的原位合成方法 |
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CN201310281414.1A CN103319506B (zh) | 2013-07-05 | 2013-07-05 | 一种[Cu2(L3)2]的原位合成方法 |
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CN103319506A true CN103319506A (zh) | 2013-09-25 |
CN103319506B CN103319506B (zh) | 2015-12-23 |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103524536A (zh) * | 2013-10-20 | 2014-01-22 | 桂林理工大学 | [Cu2(L4)2]·(CH3OH)配合物及合成方法 |
CN103524537A (zh) * | 2013-10-20 | 2014-01-22 | 桂林理工大学 | 一种[Cu2(L5)2]·(CH3OH)配合物及合成方法 |
CN103819453A (zh) * | 2014-02-19 | 2014-05-28 | 桂林理工大学 | 一种[Cu2(L2)2]·H2O配合物及原位合成方法 |
CN103880870A (zh) * | 2014-04-05 | 2014-06-25 | 桂林理工大学 | 一种配合物[Cu2(L8)(L9)]·(C3H7OH)·(H2O)及原位合成方法 |
CN104447817A (zh) * | 2014-12-19 | 2015-03-25 | 桂林理工大学 | 一种配合物[[Cu2(L7)(L10)]的原位合成及作为抗癌药物的应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1223264A (zh) * | 1993-08-03 | 1999-07-21 | 杜邦药品公司 | 制备放射性核素配合物用的硫酸三异腈亚铜 |
CN102206189A (zh) * | 2011-04-14 | 2011-10-05 | 四川大学 | 在水相中催化邻卤代苯胺制备吩嗪类化合物的方法 |
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2013
- 2013-07-05 CN CN201310281414.1A patent/CN103319506B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1223264A (zh) * | 1993-08-03 | 1999-07-21 | 杜邦药品公司 | 制备放射性核素配合物用的硫酸三异腈亚铜 |
CN102206189A (zh) * | 2011-04-14 | 2011-10-05 | 四川大学 | 在水相中催化邻卤代苯胺制备吩嗪类化合物的方法 |
Non-Patent Citations (2)
Title |
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LI-QUN SHEN,ET AL.: ""Synthesis, crystal structure, computational study of 1-(6-chloro-pyridin-2-yl)-5-hydroxy-1H-pyrazole-3-carboxylic acid methyl ester and its 5-acetoxy analogs"", 《JOURNAL OF MOLECULAR STRUCTURE》, vol. 1021, 4 April 2012 (2012-04-04), pages 167 - 173 * |
钟凡 等: ""牛磺酸合铜螯合物的合成及晶体结构"", 《无机化学学报》, vol. 19, no. 6, 30 June 2003 (2003-06-30), pages 599 - 602 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103524536A (zh) * | 2013-10-20 | 2014-01-22 | 桂林理工大学 | [Cu2(L4)2]·(CH3OH)配合物及合成方法 |
CN103524537A (zh) * | 2013-10-20 | 2014-01-22 | 桂林理工大学 | 一种[Cu2(L5)2]·(CH3OH)配合物及合成方法 |
CN103819453A (zh) * | 2014-02-19 | 2014-05-28 | 桂林理工大学 | 一种[Cu2(L2)2]·H2O配合物及原位合成方法 |
CN103880870A (zh) * | 2014-04-05 | 2014-06-25 | 桂林理工大学 | 一种配合物[Cu2(L8)(L9)]·(C3H7OH)·(H2O)及原位合成方法 |
CN104447817A (zh) * | 2014-12-19 | 2015-03-25 | 桂林理工大学 | 一种配合物[[Cu2(L7)(L10)]的原位合成及作为抗癌药物的应用 |
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CN103319506B (zh) | 2015-12-23 |
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Effective date of registration: 20201223 Address after: 11 / F, Jingang building, south of Lianyungang Road, Sheyang Economic Development Zone, Sheyang County, Yancheng City, Jiangsu Province 224300 Patentee after: Li Zaigao Address before: 541004 the Guangxi Zhuang Autonomous Region Guilin Construction Road No. 12 Patentee before: GUILIN University OF TECHNOLOGY |
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Effective date of registration: 20230103 Address after: Room 707, Administrative Committee of Tancheng Economic Development Zone, Linyi City, Shandong Province, 276100 Patentee after: Tancheng Economic Development Zone Pharmaceutical Development Co.,Ltd. Address before: 11 / F, Jingang building, south of Lianyungang Road, Sheyang Economic Development Zone, Sheyang County, Yancheng City, Jiangsu Province 224300 Patentee before: Li Zaigao |
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