CN103298464A - 复方组合物 - Google Patents

复方组合物 Download PDF

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Publication number
CN103298464A
CN103298464A CN2011800525659A CN201180052565A CN103298464A CN 103298464 A CN103298464 A CN 103298464A CN 2011800525659 A CN2011800525659 A CN 2011800525659A CN 201180052565 A CN201180052565 A CN 201180052565A CN 103298464 A CN103298464 A CN 103298464A
Authority
CN
China
Prior art keywords
ibuprofen
acetaminophen
combination
composition
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011800525659A
Other languages
English (en)
Chinese (zh)
Inventor
哈特莱·坎贝尔·爱金逊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AFT Pharmaceuticals Ltd
Original Assignee
AFT Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46024668&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN103298464(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by AFT Pharmaceuticals Ltd filed Critical AFT Pharmaceuticals Ltd
Priority to CN201710623266.5A priority Critical patent/CN107519159A/zh
Publication of CN103298464A publication Critical patent/CN103298464A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
CN2011800525659A 2010-11-04 2011-10-26 复方组合物 Pending CN103298464A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710623266.5A CN107519159A (zh) 2010-11-04 2011-10-26 复方组合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ58901110 2010-11-04
NZ589011 2010-11-04
PCT/NZ2011/000226 WO2012060719A1 (en) 2010-11-04 2011-10-26 A combination composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201710623266.5A Division CN107519159A (zh) 2010-11-04 2011-10-26 复方组合物

Publications (1)

Publication Number Publication Date
CN103298464A true CN103298464A (zh) 2013-09-11

Family

ID=46024668

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2011800525659A Pending CN103298464A (zh) 2010-11-04 2011-10-26 复方组合物
CN201710623266.5A Pending CN107519159A (zh) 2010-11-04 2011-10-26 复方组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201710623266.5A Pending CN107519159A (zh) 2010-11-04 2011-10-26 复方组合物

Country Status (28)

Country Link
US (6) US20130225685A1 (enExample)
EP (1) EP2635269B1 (enExample)
JP (2) JP2013541583A (enExample)
KR (1) KR101900520B1 (enExample)
CN (2) CN103298464A (enExample)
AU (1) AU2011324137B2 (enExample)
BR (1) BR112013010829B8 (enExample)
CA (1) CA2814057C (enExample)
CL (1) CL2013001250A1 (enExample)
CO (1) CO6771406A2 (enExample)
CY (1) CY1123398T1 (enExample)
DK (1) DK2635269T3 (enExample)
ES (1) ES2742373T3 (enExample)
HR (1) HRP20191489T1 (enExample)
HU (1) HUE045442T2 (enExample)
LT (1) LT2635269T (enExample)
MX (2) MX367209B (enExample)
MY (1) MY160572A (enExample)
NZ (1) NZ609727A (enExample)
PH (2) PH12013500689A1 (enExample)
PL (1) PL2635269T3 (enExample)
PT (1) PT2635269T (enExample)
RS (1) RS59258B1 (enExample)
RU (2) RU2707089C2 (enExample)
SG (1) SG189319A1 (enExample)
SI (1) SI2635269T1 (enExample)
SM (1) SMT201900481T1 (enExample)
WO (1) WO2012060719A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106794163A (zh) * 2014-07-18 2017-05-31 光大制药有限公司 包含对乙酰氨基酚和布洛芬的水性制剂
CN106999454A (zh) * 2014-10-06 2017-08-01 坎伯兰医药品股份有限公司 共同施用静脉内布洛芬和对乙酰氨基酚以治疗疼痛
CN113795243A (zh) * 2019-02-27 2021-12-14 Aft制药有限公司 含有对乙酰氨基酚和布洛芬的药物组合物
US11413241B2 (en) 2017-04-20 2022-08-16 Hyloris Developments Sa Method for preparing a composition with a low dissolved oxygen content, comprising acetaminophen, and optionally one or more NSAIDs, and a composition obtained thereof

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013541583A (ja) 2010-11-04 2013-11-14 エイエフティ ファーマスーティカルズ リミテッド 組み合わせ組成物
US9072710B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
AU2018300075B2 (en) * 2017-07-10 2024-02-29 Gel Cap Technologies, LLC Dual release dosage form capsule and methods, devices and systems for making same
US11568752B2 (en) * 2020-01-28 2023-01-31 David Clark Company Incorporated Gateway retrieval alert device for aircraft pushback operations
WO2023281089A2 (en) 2021-07-08 2023-01-12 Krka, D.D., Novo Mesto Pharmaceutical composition comprising naproxen and paracetamol
AU2024281739A1 (en) 2023-06-02 2025-11-27 Ioulia Tseti Pharmaceutical composition comprising ibuprofen
GR1010769B (el) * 2023-07-27 2024-09-18 Ιουλια Κλεωνος Τσετη Υδατικο διαλυμα ιβουπροφαινης για χρηση σε ενδοφλεβια χορηγηση
GR1010809B (el) * 2023-09-13 2024-10-25 Ιουλια Τσετη Υδατικο διαλυμα ιβουπροφαινης παρακεταμολης για χρηση σε ενδοφλεβια χορηγηση

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1758904A (zh) * 2003-03-21 2006-04-12 麦克内尔-Ppc股份有限公司 非甾体抗炎药物的给药方案
KR20060072839A (ko) * 2004-12-23 2006-06-28 김경태 아세트아미노펜과 이부프로펜을 이용하여 통증조절과 해열작용을 하는 주사제
CN101022789A (zh) * 2004-07-07 2007-08-22 Aft制药有限公司 一种药物组合物
WO2008079818A2 (en) * 2006-12-21 2008-07-03 Soluprin Pharmaceuticals, Inc. Intravenous administration of water soluble analgesic formulations
US20090264530A1 (en) * 2008-04-16 2009-10-22 Nickell Robert P Combined nsaid and acetaminophen formulation and method

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997020551A1 (en) * 1995-12-05 1997-06-12 Adcock Ingram Limited Pharmaceutical composition comprising a skeletal muscle relaxant, a non-steroidal antiinflammatory agent and an analgesic
CN1302771C (zh) * 2001-11-02 2007-03-07 坎伯兰医药品股份有限公司 2-(4-异丁苯基)丙酸的药物组合物
US7934627B2 (en) * 2005-10-13 2011-05-03 Alcoa Inc. Apparatus and method for high pressure extrusion with molten aluminum
CN101563074B (zh) * 2006-10-20 2012-11-07 麦克内尔-Ppc股份有限公司 乙酰氨基酚/布洛芬组合
US20110166234A1 (en) * 2008-10-14 2011-07-07 Atkinson Hartley Campbell Medicinal product and treatment
BRPI1006222A2 (pt) * 2009-03-12 2016-08-02 Cumberland Pharmaceuticas Inc uso de ibuprofeno na redução de dor em pacientes humanos que são submetidos a cirurgia, uso de ibuprofeno na redução de dor cirúrgica em pacientes humanos e uso de ibuprofeno para melhorar o tempo ambulatorial após a operação em pacientes humanos que sorem procedimentos cirúrgicos ortopédicos
AU2011274652B2 (en) * 2010-07-07 2013-08-15 Aft Pharmaceuticals Limited A combination composition comprising ibuprofen and paracetamol
JP2013541583A (ja) 2010-11-04 2013-11-14 エイエフティ ファーマスーティカルズ リミテッド 組み合わせ組成物
CA2963916A1 (en) * 2014-10-06 2016-04-14 Cumberland Pharmaceuticals, Inc. Co-administration of intravenous ibuprofen and acetaminophen for treatment of pain

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1758904A (zh) * 2003-03-21 2006-04-12 麦克内尔-Ppc股份有限公司 非甾体抗炎药物的给药方案
CN101022789A (zh) * 2004-07-07 2007-08-22 Aft制药有限公司 一种药物组合物
KR20060072839A (ko) * 2004-12-23 2006-06-28 김경태 아세트아미노펜과 이부프로펜을 이용하여 통증조절과 해열작용을 하는 주사제
WO2008079818A2 (en) * 2006-12-21 2008-07-03 Soluprin Pharmaceuticals, Inc. Intravenous administration of water soluble analgesic formulations
US20090264530A1 (en) * 2008-04-16 2009-10-22 Nickell Robert P Combined nsaid and acetaminophen formulation and method

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106794163A (zh) * 2014-07-18 2017-05-31 光大制药有限公司 包含对乙酰氨基酚和布洛芬的水性制剂
CN113018258A (zh) * 2014-07-18 2021-06-25 海罗利斯制药股份公司 包含对乙酰氨基酚和布洛芬的水性制剂
US11213498B2 (en) 2014-07-18 2022-01-04 Hyloris Pharmaceuticals S.A. Aqueous formulation comprising paracetamol and ibuprofen
US11219609B2 (en) 2014-07-18 2022-01-11 Hyloris Pharmaceuticals SA Aqueous formulation comprising paracetamol and ibuprofen
US11389416B2 (en) 2014-07-18 2022-07-19 Hyloris Pharmaceuticals SA Aqueous formulation comprising paracetamol and ibuprofen
US12083087B2 (en) 2014-07-18 2024-09-10 Hyloris Pharmaceuticals SA Aqueous formulation comprising paracetamol and ibuprofen
CN106999454A (zh) * 2014-10-06 2017-08-01 坎伯兰医药品股份有限公司 共同施用静脉内布洛芬和对乙酰氨基酚以治疗疼痛
US11413241B2 (en) 2017-04-20 2022-08-16 Hyloris Developments Sa Method for preparing a composition with a low dissolved oxygen content, comprising acetaminophen, and optionally one or more NSAIDs, and a composition obtained thereof
CN113795243A (zh) * 2019-02-27 2021-12-14 Aft制药有限公司 含有对乙酰氨基酚和布洛芬的药物组合物
US11534407B2 (en) 2019-02-27 2022-12-27 Aft Pharmaceuticals Limited Pharmaceutical compostion containing acetominophen and ibuprofen
US11872317B2 (en) 2019-02-27 2024-01-16 Aft Pharmaceuticals Limited Pharmaceutical composition containing acetominophen and ibuprofen
US12194151B2 (en) 2019-02-27 2025-01-14 Aft Pharmaceuticals Limited Pharmaceutical compostion containing acetominophen and ibuprofen

Also Published As

Publication number Publication date
BR112013010829B1 (pt) 2021-12-21
RU2707089C2 (ru) 2019-11-22
MX2013005113A (es) 2013-06-03
US20130225685A1 (en) 2013-08-29
US20230000805A1 (en) 2023-01-05
PH12013500689A1 (en) 2013-05-27
MX367209B (es) 2019-07-22
BR112013010829A2 (pt) 2016-08-16
RU2015103107A (ru) 2015-06-20
NZ609727A (en) 2015-07-31
SG189319A1 (en) 2013-05-31
CO6771406A2 (es) 2013-10-15
WO2012060719A1 (en) 2012-05-10
MY160572A (en) 2017-03-15
JP6353577B2 (ja) 2018-07-04
HUE045442T2 (hu) 2019-12-30
CA2814057A1 (en) 2012-05-10
US12220392B2 (en) 2025-02-11
CY1123398T1 (el) 2021-10-29
RS59258B1 (sr) 2019-10-31
US20190029982A1 (en) 2019-01-31
CL2013001250A1 (es) 2013-08-30
KR101900520B1 (ko) 2018-09-19
CN107519159A (zh) 2017-12-29
US20160235695A1 (en) 2016-08-18
AU2011324137B2 (en) 2015-05-07
SMT201900481T1 (it) 2019-11-13
PT2635269T (pt) 2019-09-04
SI2635269T1 (sl) 2019-10-30
AU2011324137A1 (en) 2013-05-02
EP2635269A1 (en) 2013-09-11
US20240207210A1 (en) 2024-06-27
LT2635269T (lt) 2019-09-10
EP2635269B1 (en) 2019-05-22
CA2814057C (en) 2022-02-01
RU2015103107A3 (enExample) 2018-08-20
DK2635269T3 (da) 2019-08-26
JP2017132791A (ja) 2017-08-03
EP2635269A4 (en) 2014-09-17
US11446266B2 (en) 2022-09-20
HRP20191489T1 (hr) 2019-11-15
JP2013541583A (ja) 2013-11-14
PH12021550804A1 (en) 2022-02-14
US11896567B2 (en) 2024-02-13
US20250134839A1 (en) 2025-05-01
PL2635269T3 (pl) 2019-11-29
BR112013010829B8 (pt) 2022-01-04
RU2013123646A (ru) 2014-12-10
ES2742373T3 (es) 2020-02-14
KR20140025314A (ko) 2014-03-04

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Legal Events

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20130911