CN103285288A - Medicament for treating chronic cardiac insufficiency - Google Patents
Medicament for treating chronic cardiac insufficiency Download PDFInfo
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- CN103285288A CN103285288A CN2013102572265A CN201310257226A CN103285288A CN 103285288 A CN103285288 A CN 103285288A CN 2013102572265 A CN2013102572265 A CN 2013102572265A CN 201310257226 A CN201310257226 A CN 201310257226A CN 103285288 A CN103285288 A CN 103285288A
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Abstract
The invention relates to a medicament for treating chronic cardiac insufficiency. The medicament is prepared from the following substances in proportions by weight: red peony root, peach kernel, white hyacinth bean, smilax china, pinellia ternata, peucedanum decursivum maxim, kapok, tuber fleeceflower stem, yam, manchurian lilac bark, sea-tangle, thlaspi arvense l, pericarpium citri reticulatae viride, spina date seed, folium sauropi, hooker winghead root, golden cypress, witloof, bighead atractylodes rhizome, dandelion, retinervus luffae fructus, semen celosiae, carthamus tinctorious, prepared rehmannia root, rhizoma dioscoreae septemlobae xerxes, orange peel, beautiful sweetgum fruit, perfoliote knotweed herb, fructus broussonetiae, common gendarussa herb, paeonia suffruticosa, angelica sinensis, rhizoma nelumbinis, herba siegesbeckiae, medulla stachyuri, fructus gardeniae, pericarpium citri reticulatae, radix bupleuri, Chinese mahonia stem, piper cubeba, concha arcae, poria cocos, cassia twig, rhizoma cyperi, spatholobus suberctu and citron. The medicament for treating the chronic cardiac insufficiency is prepared from all natural medicines, is definite in curative effect, can be used for effectively treating the chronic cardiac insufficiency, thereby being very suitable for clinical promotion.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of chronic cardiac insufficiency.
Background technology
Chronic cardiac insufficiency is clinical common disease, is more common in advanced age, infection, heart basal disease, bad life habits patient, and this disease can cause the dysfunction of other important organs, along with disease progression, can finally cause death.Clinical conventional therapy for chronic cardiac insufficiency is diuresis, heart tonifying, expansion blood vessel, low salt diet, rest etc., and curative effect is very unobvious.The Chinese traditional treatment chronic cardiac insufficiency is used and is given birth to, and is subjected to the extensive concern of all circles in recent years.
Summary of the invention
The purpose of this invention is to provide a kind of medicament for the treatment of chronic cardiac insufficiency.
In order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of chronic cardiac insufficiency, it is to be made by following materials by weight: Radix Paeoniae Rubra 20-30 part, Semen Persicae 10-20 part, Semen Lablab Album 30-40 part, Rhizoma Smilacis Chinensis 10-20 part, Rhizoma Pinelliae 15-30 part, RADIX PEUCEDANI 1-10 part, Flos Bombacis Malabarici 20-40 part, Caulis Polygoni Multiflori 1-20 part, Rhizoma Dioscoreae 20-30 part, Cortex Syingae Amurensis 1-20 part, Thallus Laminariae (Thallus Eckloniae) 20-30 part, Xi beanstalk 10-30 part, Pericarpium Citri Reticulatae Viride 10-30 part, Semen Ziziphi Spinosae 20-30 part, Folium Sauropi 10-20 part, Herba pterocephali 5-15 part, Cortex Phellodendri 1-10 part, Herba Cichorii 15-25 part, Rhizoma Atractylodis Macrocephalae 15-40 part, Herba Taraxaci 10-30 part, Retinervus Luffae Fructus 1-20 part, Semen Celosiae 5-15 part, Flos Carthami 20-40 part, Radix Rehmanniae Preparata 30-50 part, Dioscorea septemloba Thunb. Pi 10-20 part, Pericarpium Citri tangerinae 10-20 part, Fructus Liquidambaris 20-30 part, Herba Polygoni cymosi 10-30 part, Fructus Broussonetiae 1-20 part, Herba Gendarussae 10-20 part, Cortex Moutan 10-30 part, Radix Angelicae Sinensis 1-15 part, Nodus Nelumbinis Rhizomatis 10-20 part Herba Siegesbeckiae 10-20 part, Medulla Stachyuri (Medulla Helwingiae) 20-30 part, Fructus Gardeniae 20-40 part, Pericarpium Citri Reticulatae 1-20 part, Radix Bupleuri 20-30 part, Caulis Mahoniae 1-10 part, Fructus Litseae 20-30 part, Concha Arcae 1-20 part, Poria 1-20 part, Ramulus Cinnamomi 10-20 part, Rhizoma Cyperi 1-10 part, Caulis Spatholobi 10-20 part and Fructus Citri 20-40 part.
Preferably, the medicament for the treatment of chronic cardiac insufficiency of the present invention is to be made by following materials by weight: 25 parts of Radix Paeoniae Rubra, 15 parts in Semen Persicae, 30 parts of Semen Lablab Albums, 15 parts of Rhizoma Smilacis Chinensiss, 20 parts of the Rhizoma Pinelliaes, 5 parts of RADIX PEUCEDANI, 20 parts of Flos Bombacis Malabaricis, 10 parts of Caulis Polygoni Multiflori, 30 parts of Rhizoma Dioscoreaes, 10 parts of Cortex Syingae Amurensiss, 30 parts of Thallus Laminariae (Thallus Eckloniae)s, 20 parts of Xi beanstalks, 20 parts on Pericarpium Citri Reticulatae Viride, 20 parts of Semen Ziziphi Spinosaes, 10 parts of Folium Sauropis, 10 parts of Herba pterocephali, 5 parts of Cortex Phellodendris, 20 parts of Herba Cichoriis, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Herba Taraxacis, 10 parts of Retinervus Luffae Fructuss, 10 parts of Semen Celosiae, 30 parts on Flos Carthami, 40 parts of Radix Rehmanniae Preparata, 15 parts of Dioscorea septemloba Thunb. Pis, 15 parts of Pericarpium Citri tangerinaes, 25 parts of Fructus Liquidambaris, 20 parts of Herba Polygoni cymosis, 10 parts of Fructus Broussonetiaes, 15 parts of Herba Gendarussaes, 20 parts of Cortex Moutans, 10 parts of Radix Angelicae Sinensis, 15 parts of 15 parts of Herba Siegesbeckiaes of Nodus Nelumbinis Rhizomatis, 25 parts of Medulla Stachyuri (Medulla Helwingiae)s, 30 parts of Fructus Gardeniaes, 10 parts of Pericarpium Citri Reticulataes, 25 parts of Radix Bupleuri, 5 parts of Caulis Mahoniaes, 25 parts of Fructus Litseae, 10 parts of Concha Arcaes, 10 parts in Poria, 15 parts of Ramulus Cinnamomi, 5 parts of Rhizoma Cyperis, 30 parts of 15 parts of Caulis Spatholobis and Fructus Citris.
More preferably, described medicament is tablet, dispersible tablet, decoction or liniment.
The medicament for the treatment of chronic cardiac insufficiency of the present invention all adopts natural drug to make, and curative effect is clear and definite, can treat chronic cardiac insufficiency effectively, therefore very suitable popularization clinically.
The specific embodiment
Further specify the present invention below by embodiment.It should be understood that embodiments of the invention are for explanation the present invention rather than limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Except as otherwise noted, otherwise the percent among the present invention is percetage by weight.
The preparation of embodiment 1 decoction
Get Radix Paeoniae Rubra 25 grams, Semen Persicae 15 grams, Semen Lablab Album 30 grams, Rhizoma Smilacis Chinensis 15 grams, the Rhizoma Pinelliae 20 grams, RADIX PEUCEDANI 5 grams, Flos Bombacis Malabarici 20 grams, Caulis Polygoni Multiflori 10 grams, Rhizoma Dioscoreae 30 grams, Cortex Syingae Amurensis 10 grams, Thallus Laminariae (Thallus Eckloniae) 30 grams, Xi beanstalk 20 grams, Pericarpium Citri Reticulatae Viride 20 grams, Semen Ziziphi Spinosae 20 grams, Folium Sauropi 10 grams, Herba pterocephali 10 grams, Cortex Phellodendri 5 grams, Herba Cichorii 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Herba Taraxaci 20 grams, Retinervus Luffae Fructus 10 grams, Semen Celosiae 10 grams, Flos Carthami 30 grams, Radix Rehmanniae Preparata 40 gram Rhizoma Dioscoreae Septemlobaes 15 grams, Pericarpium Citri tangerinae 15 grams, Fructus Liquidambaris 25 grams, Herba Polygoni cymosi 20 grams, Fructus Broussonetiae 10 grams, Herba Gendarussae 15 grams, Cortex Moutan 20 grams, Radix Angelicae Sinensis 10 grams, Nodus Nelumbinis Rhizomatis 15 gram Herba Siegesbeckiaes 15 grams, Medulla Stachyuri (Medulla Helwingiae) 25 grams, Fructus Gardeniae 30 grams, Pericarpium Citri Reticulatae 10 grams, Radix Bupleuri 25 grams, Caulis Mahoniae 5 grams, Fructus Litseae 25 grams, Concha Arcae 10 grams, Poria 10 grams, Ramulus Cinnamomi 15 grams, Rhizoma Cyperi 5 grams, Caulis Spatholobi 15 grams and Fructus Citri 30 grams, add 5000 ml waters, heated 3 hours down at 100 ℃, be cooled to room temperature.Filter, filtrate is concentrated into 1000 milliliters, is cooled to room temperature, is decoction of the present invention.
Experimental example
Diagnostic criteria
Western medicine diagnose standard reference Framingham heart failure diagnostic criteria and cardiac functional grading standard (angiocardiology branch of Chinese Medical Association of USA New York heart association (NYHA), China cardiovascular diseases magazine editorial board. systolic heart failure treatment suggestion [J]. Chinese cardiovascular diseases's magazine, 2002,30 (1): 7-23.), cardiac functional grading is pressed I level, II level, III level, the evaluation of N level.
Select chronic cardiac insufficiency patient 48 examples, all patients all meet the chronic cardiac insufficiency diagnostic criteria of clinical and iconography.Male's 25 examples wherein, women's 23 examples, year at age (59-82), average (67.6 ± 5.44) year, course of disease 1-3, average (1.23 ± 0.35) year, rheumatic heart disease 9 examples wherein, hypertensive cardiopathy 15 examples, coronary heart disease 17 examples, dilated cardiomyopathy 7 examples.
Use the decoction of embodiment 1 preparation to treat, one day twice, take 150 milliliters at every turn, treating for three weeks continuously is a course for the treatment of.
Efficacy assessment standard
Observation index BNP and EP1 level: gather venous blood after the patient people institute, 3000r/min, 4 ℃, centrifugal 10min collect upper serum and in-80 ℃ of preservations.Select ELISA test kit and microplate reader to detect, adopt enzyme linked immunosorbent assay (ELISA) to measure Type B natriuretic peptide (BNP) and two indexs of big ET-1 (EP1).
Reference " new Chinese medicine clinical research guideline " (State Food and Drug Administration. new Chinese medicine clinical research guideline [s]. Beijing: Chinese Medicine science and technology publishing house, 2002:77-85.) the cardiac function criterion of therapeutical effect is divided into:
Produce effects: BNP and EP1 level are being treated all reduction persons of front and back;
Effectively: one in BNP and the EP1 level be reduction person before and after treatment;
Invalid: BNP and EP1 level all do not have reduction person before and after treatment.
The result
After treatment, 48 routine patients' BNP and EP1 level all reduce before and after treatment, therefore all meet the efficacy assessment standard of produce effects.
Untoward reaction
In therapeutic process, carry out tracing observation for the patient, do not find tangible untoward reaction.
Claims (3)
1. medicament for the treatment of chronic cardiac insufficiency, it is characterized in that it is to be made by following materials by weight: Radix Paeoniae Rubra 20-30 part, Semen Persicae 10-20 part, Semen Lablab Album 30-40 part, Rhizoma Smilacis Chinensis 10-20 part, Rhizoma Pinelliae 15-30 part, RADIX PEUCEDANI 1-10 part, Flos Bombacis Malabarici 20-40 part, Caulis Polygoni Multiflori 1-20 part, Rhizoma Dioscoreae 20-30 part, Cortex Syingae Amurensis 1-20 part, Thallus Laminariae (Thallus Eckloniae) 20-30 part, Xi beanstalk 10-30 part, Pericarpium Citri Reticulatae Viride 10-30 part, Semen Ziziphi Spinosae 20-30 part, Folium Sauropi 10-20 part, Herba pterocephali 5-15 part, Cortex Phellodendri 1-10 part, Herba Cichorii 15-25 part, Rhizoma Atractylodis Macrocephalae 15-40 part, Herba Taraxaci 10-30 part, Retinervus Luffae Fructus 1-20 part, Semen Celosiae 5-15 part, Flos Carthami 20-40 part, Radix Rehmanniae Preparata 30-50 part Rhizoma Dioscoreae Septemlobae 10-20 part, Pericarpium Citri tangerinae 10-20 part, Fructus Liquidambaris 20-30 part, Herba Polygoni cymosi 10-30 part, Fructus Broussonetiae 1-20 part, Herba Gendarussae 10-20 part, Cortex Moutan 10-30 part, Radix Angelicae Sinensis 1-15 part, Nodus Nelumbinis Rhizomatis 10-20 part Herba Siegesbeckiae 10-20 part, Medulla Stachyuri (Medulla Helwingiae) 20-30 part, Fructus Gardeniae 20-40 part, Pericarpium Citri Reticulatae 1-20 part, Radix Bupleuri 20-30 part, Caulis Mahoniae 1-10 part, Fructus Litseae 20-30 part, Concha Arcae 1-20 part, Poria 1-20 part, Ramulus Cinnamomi 10-20 part, Rhizoma Cyperi 1-10 part, Caulis Spatholobi 10-20 part and Fructus Citri 20-40 part.
2. the medicament for the treatment of chronic cardiac insufficiency according to claim 1, it is characterized in that it is to be made by following materials by weight: 25 parts of Radix Paeoniae Rubra, 15 parts in Semen Persicae, 30 parts of Semen Lablab Albums, 15 parts of Rhizoma Smilacis Chinensiss, 20 parts of the Rhizoma Pinelliaes, 5 parts of RADIX PEUCEDANI, 20 parts of Flos Bombacis Malabaricis, 10 parts of Caulis Polygoni Multiflori, 30 parts of Rhizoma Dioscoreaes, 10 parts of Cortex Syingae Amurensiss, 30 parts of Thallus Laminariae (Thallus Eckloniae)s, 20 parts of Xi beanstalks, 20 parts on Pericarpium Citri Reticulatae Viride, 20 parts of Semen Ziziphi Spinosaes, 10 parts of Folium Sauropis, 10 parts of Herba pterocephali, 5 parts of Cortex Phellodendris, 20 parts of Herba Cichoriis, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Herba Taraxacis, 10 parts of Retinervus Luffae Fructuss, 10 parts of Semen Celosiae, 30 parts on Flos Carthami, 40 parts of Radix Rehmanniae Preparata, 15 parts of Dioscorea septemloba Thunb. Pis, 15 parts of Pericarpium Citri tangerinaes, 25 parts of Fructus Liquidambaris, 20 parts of Herba Polygoni cymosis, 10 parts of Fructus Broussonetiaes, 15 parts of Herba Gendarussaes, 20 parts of Cortex Moutans, 10 parts of Radix Angelicae Sinensis, 15 parts of 15 parts of Herba Siegesbeckiaes of Nodus Nelumbinis Rhizomatis, 25 parts of Medulla Stachyuri (Medulla Helwingiae)s, 30 parts of Fructus Gardeniaes, 10 parts of Pericarpium Citri Reticulataes, 25 parts of Radix Bupleuri, 5 parts of Caulis Mahoniaes, 25 parts of Fructus Litseae, 10 parts of Concha Arcaes, 10 parts in Poria, 15 parts of Ramulus Cinnamomi, 5 parts of Rhizoma Cyperis, 30 parts of 15 parts of Caulis Spatholobis and Fructus Citris.
3. the medicament for the treatment of chronic cardiac insufficiency according to claim 1 and 2 is characterized in that, described medicament is tablet, dispersible tablet, decoction or liniment.
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| CN201310257226.5A CN103285288B (en) | 2013-06-26 | 2013-06-26 | Medicament for treating chronic cardiac insufficiency |
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| CN201310257226.5A CN103285288B (en) | 2013-06-26 | 2013-06-26 | Medicament for treating chronic cardiac insufficiency |
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| CN103285288B CN103285288B (en) | 2015-02-18 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103495139A (en) * | 2013-10-11 | 2014-01-08 | 陈国军 | Chinese medicine composition for treating heart disease |
| CN103520589A (en) * | 2013-10-11 | 2014-01-22 | 陈国军 | Medicament used for treating heart diseases |
| CN113243531A (en) * | 2021-06-02 | 2021-08-13 | 膳行天下(吉林)科技发展有限公司 | Medicated food for people with high uric acid content |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579794A (en) * | 2012-02-21 | 2012-07-18 | 姜永梅 | Chinese herbal preparation, tablet, oral liquid and decoction for treating chronic heart failure and preparation method thereof |
| CN102772748A (en) * | 2012-08-21 | 2012-11-14 | 杨高林 | Traditional Chinese medicine preparation for treating liver-depression qi-stagnation type viral myocarditis and preparation method thereof |
| CN102846937A (en) * | 2012-08-31 | 2013-01-02 | 霍山县中医院 | Chinese herbal medicine for treating dilated cardiomyopathy |
-
2013
- 2013-06-26 CN CN201310257226.5A patent/CN103285288B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579794A (en) * | 2012-02-21 | 2012-07-18 | 姜永梅 | Chinese herbal preparation, tablet, oral liquid and decoction for treating chronic heart failure and preparation method thereof |
| CN102772748A (en) * | 2012-08-21 | 2012-11-14 | 杨高林 | Traditional Chinese medicine preparation for treating liver-depression qi-stagnation type viral myocarditis and preparation method thereof |
| CN102846937A (en) * | 2012-08-31 | 2013-01-02 | 霍山县中医院 | Chinese herbal medicine for treating dilated cardiomyopathy |
Non-Patent Citations (2)
| Title |
|---|
| 柯有甫: "慢性心功能不全的中医药防治", 《亚太传统医药》 * |
| 袁宝瑞: "气血痰愈汤治疗慢性心功能不全52例疗效观察", 《中西医结合心脑血管病杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103495139A (en) * | 2013-10-11 | 2014-01-08 | 陈国军 | Chinese medicine composition for treating heart disease |
| CN103520589A (en) * | 2013-10-11 | 2014-01-22 | 陈国军 | Medicament used for treating heart diseases |
| CN113243531A (en) * | 2021-06-02 | 2021-08-13 | 膳行天下(吉林)科技发展有限公司 | Medicated food for people with high uric acid content |
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| CN103285288B (en) | 2015-02-18 |
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