CN103285288B - Medicament for treating chronic cardiac insufficiency - Google Patents
Medicament for treating chronic cardiac insufficiency Download PDFInfo
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- CN103285288B CN103285288B CN201310257226.5A CN201310257226A CN103285288B CN 103285288 B CN103285288 B CN 103285288B CN 201310257226 A CN201310257226 A CN 201310257226A CN 103285288 B CN103285288 B CN 103285288B
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Abstract
The invention relates to a medicament for treating chronic cardiac insufficiency. The medicament is prepared from the following substances in proportions by weight: red peony root, peach kernel, white hyacinth bean, smilax china, pinellia ternata, peucedanum decursivum maxim, kapok, tuber fleeceflower stem, yam, manchurian lilac bark, sea-tangle, thlaspi arvense l, pericarpium citri reticulatae viride, spina date seed, folium sauropi, hooker winghead root, golden cypress, witloof, bighead atractylodes rhizome, dandelion, retinervus luffae fructus, semen celosiae, carthamus tinctorious, prepared rehmannia root, rhizoma dioscoreae septemlobae xerxes, orange peel, beautiful sweetgum fruit, perfoliote knotweed herb, fructus broussonetiae, common gendarussa herb, paeonia suffruticosa, angelica sinensis, rhizoma nelumbinis, herba siegesbeckiae, medulla stachyuri, fructus gardeniae, pericarpium citri reticulatae, radix bupleuri, Chinese mahonia stem, piper cubeba, concha arcae, poria cocos, cassia twig, rhizoma cyperi, spatholobus suberctu and citron. The medicament for treating the chronic cardiac insufficiency is prepared from all natural medicines, is definite in curative effect, can be used for effectively treating the chronic cardiac insufficiency, thereby being very suitable for clinical promotion.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of chronic cardiac insufficiency.
Background technology
Chronic cardiac insufficiency is clinical common disease, and be more common in advanced age, infection, heart basal disease, bad life habits patient, this disease can cause the dysfunction of other important organs, along with disease progression, finally can cause death.The clinical conventional therapy for chronic cardiac insufficiency is diuresis, heart tonifying, expansion blood vessel, low salt diet, rest etc., and curative effect is very unobvious.Chinese traditional treatment chronic cardiac insufficiency is applied and gives birth to, and is subject to the extensive concern of all circles in recent years.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of chronic cardiac insufficiency.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of chronic cardiac insufficiency, it is made up of the material of following weight proportioning: Radix Paeoniae Rubra 20-30 part, Semen Persicae 10-20 part, Semen Lablab Album 30-40 part, Rhizoma Smilacis Chinensis 10-20 part, Rhizoma Pinelliae 15-30 part, RADIX PEUCEDANI 1-10 part, Flos Bombacis Malabarici 20-40 part, Caulis Polygoni Multiflori 1-20 part, Rhizoma Dioscoreae 20-30 part, Cortex Syingae Amurensis 1-20 part, Thallus Laminariae (Thallus Eckloniae) 20-30 part, Xi beanstalk 10-30 part, Pericarpium Citri Reticulatae Viride 10-30 part, Semen Ziziphi Spinosae 20-30 part, Folium Sauropi 10-20 part, Herba pterocephali 5-15 part, Cortex Phellodendri 1-10 part, Herba Cichorii 15-25 part, Rhizoma Atractylodis Macrocephalae 15-40 part, Herba Taraxaci 10-30 part, Retinervus Luffae Fructus 1-20 part, Semen Celosiae 5-15 part, Flos Carthami 20-40 part, Radix Rehmanniae Preparata 30-50 part, Dioscorea septemloba Thunb. Pi 10-20 part, Pericarpium Citri tangerinae 10-20 part, Fructus Liquidambaris 20-30 part, Herba Polygoni cymosi 10-30 part, Fructus Broussonetiae 1-20 part, Herba Gendarussae 10-20 part, Cortex Moutan 10-30 part, Radix Angelicae Sinensis 1-15 part, Nodus Nelumbinis Rhizomatis 10-20 part, Herba Siegesbeckiae 10-20 part, Medulla Stachyuri (Medulla Helwingiae) 20-30 part, Fructus Gardeniae 20-40 part, Pericarpium Citri Reticulatae 1-20 part, Radix Bupleuri 20-30 part, Caulis Mahoniae 1-10 part, Fructus Litseae 20-30 part, Concha Arcae 1-20 part, Poria 1-20 part, Ramulus Cinnamomi 10-20 part, Rhizoma Cyperi 1-10 part, Caulis Spatholobi 10-20 part and Fructus Citri 20-40 part.
Preferably, the medicament for the treatment of chronic cardiac insufficiency of the present invention is made up of the material of following weight proportioning: Radix Paeoniae Rubra 25 parts, 15 parts, Semen Persicae, Semen Lablab Album 30 parts, Rhizoma Smilacis Chinensis 15 parts, the Rhizoma Pinelliae 20 parts, RADIX PEUCEDANI 5 parts, Flos Bombacis Malabarici 20 parts, Caulis Polygoni Multiflori 10 parts, Rhizoma Dioscoreae 30 parts, Cortex Syingae Amurensis 10 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, Xi beanstalk 20 parts, 20 parts, Pericarpium Citri Reticulatae Viride, Semen Ziziphi Spinosae 20 parts, Folium Sauropi 10 parts, Herba pterocephali 10 parts, Cortex Phellodendri 5 parts, Herba Cichorii 20 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Herba Taraxaci 20 parts, Retinervus Luffae Fructus 10 parts, Semen Celosiae 10 parts, 30 parts, Flos Carthami, Radix Rehmanniae Preparata 40 parts, Dioscorea septemloba Thunb. Pi 15 parts, Pericarpium Citri tangerinae 15 parts, Fructus Liquidambaris 25 parts, Herba Polygoni cymosi 20 parts, Fructus Broussonetiae 10 parts, Herba Gendarussae 15 parts, Cortex Moutan 20 parts, Radix Angelicae Sinensis 10 parts, Nodus Nelumbinis Rhizomatis 15 parts, Herba Siegesbeckiae 15 parts, Medulla Stachyuri (Medulla Helwingiae) 25 parts, Fructus Gardeniae 30 parts, Pericarpium Citri Reticulatae 10 parts, Radix Bupleuri 25 parts, Caulis Mahoniae 5 parts, Fructus Litseae 25 parts, Concha Arcae 10 parts, 10 parts, Poria, Ramulus Cinnamomi 15 parts, Rhizoma Cyperi 5 parts, Caulis Spatholobi 15 parts and Fructus Citri 30 parts.
More preferably, described medicament is tablet, dispersible tablet, decoction or liniment.
The medicament for the treatment of chronic cardiac insufficiency of the present invention all adopts natural drug to make, and clear curative effect, can treat chronic cardiac insufficiency effectively, therefore very suitablely promotes clinically.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
The preparation of embodiment 1 decoction
Get Radix Paeoniae Rubra 25 grams, 15 grams, Semen Persicae, Semen Lablab Album 30 grams, Rhizoma Smilacis Chinensis 15 grams, the Rhizoma Pinelliae 20 grams, RADIX PEUCEDANI 5 grams, Flos Bombacis Malabarici 20 grams, Caulis Polygoni Multiflori 10 grams, Rhizoma Dioscoreae 30 grams, Cortex Syingae Amurensis 10 grams, Thallus Laminariae (Thallus Eckloniae) 30 grams, Xi beanstalk 20 grams, 20 grams, Pericarpium Citri Reticulatae Viride, Semen Ziziphi Spinosae 20 grams, Folium Sauropi 10 grams, Herba pterocephali 10 grams, Cortex Phellodendri 5 grams, Herba Cichorii 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Herba Taraxaci 20 grams, Retinervus Luffae Fructus 10 grams, Semen Celosiae 10 grams, 30 grams, Flos Carthami, Radix Rehmanniae Preparata 40 grams, Rhizoma Dioscoreae Septemlobae 15 grams, Pericarpium Citri tangerinae 15 grams, Fructus Liquidambaris 25 grams, Herba Polygoni cymosi 20 grams, Fructus Broussonetiae 10 grams, Herba Gendarussae 15 grams, Cortex Moutan 20 grams, Radix Angelicae Sinensis 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Herba Siegesbeckiae 15 grams, Medulla Stachyuri (Medulla Helwingiae) 25 grams, Fructus Gardeniae 30 grams, Pericarpium Citri Reticulatae 10 grams, Radix Bupleuri 25 grams, Caulis Mahoniae 5 grams, Fructus Litseae 25 grams, Concha Arcae 10 grams, 10 grams, Poria, Ramulus Cinnamomi 15 grams, Rhizoma Cyperi 5 grams, Caulis Spatholobi 15 grams and Fructus Citri 30 grams, add 5000 ml waters, heat 3 hours at 100 DEG C, be cooled to room temperature.Filter, filtrate is concentrated into 1000 milliliters, is cooled to room temperature, is decoction of the present invention.
Experimental example
Diagnostic criteria
Western medicine diagnose standard is with reference to Framingham diagnosing patients with heart failure standard and USA New York heart association (NYHA) cardiac functional grading standard (angiocardiology branch of Chinese Medical Association, Chinese Journal of Cardiology editorial board. systolic heart failure treatment suggestion [J]. Chinese Journal of Cardiology, 2002,30 (1): 7-23.), cardiac functional grading presses I level, II level, III level, the evaluation of N level.
Select chronic cardiac insufficiency patient 48 example, all patients all meet chronic cardiac insufficiency diagnostic criteria that is clinical and iconography.Wherein male 25 example, women 23 example, the age (59-82) year, average (67.6 ± 5.44) year, course of disease 1-3, average (1.23 ± 0.35) year, wherein rheumatic heart disease 9 example, hypertensive cardiopathy 15 example, coronary heart disease 17 example, dilated cardiomyopathy 7 example.
The decoction using embodiment 1 to prepare is treated, one day twice, and each serving with 150 milliliters, three week for the treatment of is a course for the treatment of continuously.
Efficacy assessment standard
Observation index BNP and EP1 level: gather venous blood after patient people institute, 3000r/min, 4 DEG C, centrifugal 10min, collect upper serum in-80 DEG C of preservations.Select ELISA kit and microplate reader to detect, adopt enzyme linked immunosorbent assay (ELISA) to measure BNP (BNP) and Big ET-1 (EP1) two indexs.
With reference to " new Chinese medicine guideline of clinical investigations " (State Food and Drug Administration. new Chinese medicine guideline of clinical investigations [s]. Beijing: China Medical Science Press, 2002:77-85.) cardiac function criterion of therapeutical effect is divided into:
Effective: BNP and EP1 level before the treatment after equal reduction persons;
Effective: the reduction person afterwards before the treatment of the one in BNP and EP1 level;
Invalid: BNP and EP1 level is rear all without reduction person before the treatment.
Result
After the treatment, BNP and the EP1 level of 48 routine patients before the treatment after all reduce, therefore all meet effective efficacy assessment standard.
Untoward reaction
Over the course for the treatment of tracing observation is carried out for patient, does not find obvious untoward reaction.
Claims (1)
1. treat a medicament for chronic cardiac insufficiency, it is characterized in that, it is made up by following method of following substances: get Radix Paeoniae Rubra 25 grams, 15 grams, Semen Persicae, Semen Lablab Album 30 grams, Rhizoma Smilacis Chinensis 15 grams, the Rhizoma Pinelliae 20 grams, RADIX PEUCEDANI 5 grams, Flos Bombacis Malabarici 20 grams, Caulis Polygoni Multiflori 10 grams, Rhizoma Dioscoreae 30 grams, Cortex Syingae Amurensis 10 grams, Thallus Laminariae (Thallus Eckloniae) 30 grams, Herba Thlaspis 20 grams, 20 grams, Pericarpium Citri Reticulatae Viride, Semen Ziziphi Spinosae 20 grams, Folium Sauropi 10 grams, Herba pterocephali 10 grams, Cortex Phellodendri 5 grams, Herba Cichorii 20 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Herba Taraxaci 20 grams, Retinervus Luffae Fructus 10 grams, Semen Celosiae 10 grams, 30 grams, Flos Carthami, Radix Rehmanniae Preparata 40 grams, Rhizoma Dioscoreae Septemlobae 15 grams, Pericarpium Citri tangerinae 15 grams, Fructus Liquidambaris 25 grams, Herba Polygoni cymosi 20 grams, Fructus Broussonetiae 10 grams, Herba Gendarussae 15 grams, Cortex Moutan 20 grams, Radix Angelicae Sinensis 10 grams, Nodus Nelumbinis Rhizomatis 15 grams, Herba Siegesbeckiae 15 grams, Medulla Stachyuri (Medulla Helwingiae) 25 grams, Fructus Gardeniae 30 grams, Pericarpium Citri Reticulatae 10 grams, Radix Bupleuri 25 grams, Caulis Mahoniae 5 grams, Fructus Litseae 25 grams, Concha Arcae 10 grams, 10 grams, Poria, Ramulus Cinnamomi 15 grams, Rhizoma Cyperi 5 grams, Caulis Spatholobi 15 grams and Fructus Citri 30 grams, add 5000 ml waters, heats 3 hours, be cooled to room temperature at 100 DEG C, and filter, filtrate is concentrated into 1000 milliliters, is cooled to room temperature.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310257226.5A CN103285288B (en) | 2013-06-26 | 2013-06-26 | Medicament for treating chronic cardiac insufficiency |
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| CN201310257226.5A CN103285288B (en) | 2013-06-26 | 2013-06-26 | Medicament for treating chronic cardiac insufficiency |
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| Publication Number | Publication Date |
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| CN103285288A CN103285288A (en) | 2013-09-11 |
| CN103285288B true CN103285288B (en) | 2015-02-18 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103495139B (en) * | 2013-10-11 | 2015-08-05 | 陈国军 | One treats cardiopathic Chinese medicine composition |
| CN103520589B (en) * | 2013-10-11 | 2015-04-15 | 陈国军 | Medicament used for treating heart diseases |
| CN113243531A (en) * | 2021-06-02 | 2021-08-13 | 膳行天下(吉林)科技发展有限公司 | Medicated food for people with high uric acid content |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102579794B (en) * | 2012-02-21 | 2013-12-04 | 姜永梅 | Chinese herbal preparation, tablet, oral liquid and decoction for treating chronic heart failure and preparation method thereof |
| CN102772748B (en) * | 2012-08-21 | 2015-03-11 | 吴彩霞 | Traditional Chinese medicine preparation for treating liver-depression qi-stagnation type viral myocarditis and preparation method thereof |
| CN102846937B (en) * | 2012-08-31 | 2013-11-06 | 霍山县中医院 | Chinese herbal medicine for treating dilated cardiomyopathy |
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