CN103316305B - Traditional Chinese medicine composition for treating liver cirrhosis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating liver cirrhosis and preparation method thereof Download PDF

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CN103316305B
CN103316305B CN201310293192.5A CN201310293192A CN103316305B CN 103316305 B CN103316305 B CN 103316305B CN 201310293192 A CN201310293192 A CN 201310293192A CN 103316305 B CN103316305 B CN 103316305B
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parts
radix
herba
rhizoma
chinese medicine
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CN103316305A (en
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华菊
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Dong Zeqing
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Abstract

The invention relates to a traditional Chinese medicine composition for treating liver cirrhosis and a preparation method thereof. The composition is prepared from the following bulk drugs: milkvetch root, red sage root, bighead atractylodes rhizome, imperata rhizome, white peony root, turmeric, virgate wormwood herb, isatis root, Poria cocos, dangshen, Plantain seed, motherwort, stringy stonecrop herb, heydyotis, verbena, Japanese eupatorium, curcuma rhizome, earthworm, Plantain seed, betel nut, Chinese angelica, oriental waterplantain rhizome, chicken's gizzard membrane, safflower, Sichuan lovage rhizome, red peony root and pseudo-ginseng. The invention has the following advantages: the traditional Chinese medicine composition has a substantial curative effect, fast action and no toxic and side effects; the preparation method is simple; etc.

Description

A kind of Chinese medicine composition for the treatment of liver cirrhosis and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine composition for the treatment of liver cirrhosis and preparation method thereof.
Background technology
Liver cirrhosis refers to due to different pathogeny long-term damage livers such as virus, malnutrition due to parasitic infestation, food and drink or medicines, cause hepatocellular degeneration, necrosis, regeneration, extensive proliferation of fibrous tissue, causes the irreversible change of liver structure gradually, hard with right flank distending pain, nauseating poor appetite, fatigue and weakness, abdomen muscle anger is opened, the red thread of red filament, purplish tongue is dark, and stringy pulse is the chronic hepatopathy of main manifestations.Liver cirrhosis is divided into compensatory phase and Decompensated stage clinically.Can there be hepatitis clinical manifestation the compensatory phase, also can have the slightly symptom such as weak, abdominal distention.Decompensated stage then damage with liver function and portal hypertension for main manifestations, also can have weak, become thin, the symptom such as dim complexion, oliguria, edema of lower limbs, abdominal distention.
At present, the medicine being used for the treatment of liver cirrhosis is more, but it exists the deficiencies such as therapeutic effect is poor, treatment time is long, side effect is large.
Summary of the invention
The advantages such as the technical problem to be solved in the present invention is: be solve the deficiencies in the prior art, the invention provides a kind of Chinese medicine composition for the treatment of liver cirrhosis and preparation method thereof, and the present invention has evident in efficacy, instant effect, has no side effect, preparation method is simple.
A kind of Chinese medicine composition for the treatment of liver cirrhosis, be made up of the crude drug of following weight portion: Radix Astragali 25-35 part, Radix Salviae Miltiorrhizae 25-35 part, Rhizoma Atractylodis Macrocephalae 25-35 part, Rhizoma Imperatae 25-35 part, Radix Paeoniae Alba 15-25 part, Rhizoma Curcumae Longae 15-25 part, Herba Artemisiae Scopariae 15-25 part, Radix Isatidis 15-25 part, Poria 10-20 part, Radix Codonopsis 10-20 part, Semen Plantaginis 10-20 part, Herba Leonuri 10-20 part, Herba Sedi 10-20 part, Herba Hedyotidis Diffusae 10-20 part, Herba Verbenae 10-20 part, Herba Lycopi 5-15 part, Rhizoma Curcumae 5-15 part, Pheretima 5-15 part, Semen Plantaginis 5-15 part, Semen Arecae 5-15 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Alismatis 5-15 part, Endothelium Corneum Gigeriae Galli 5-15 part, Flos Carthami 3-9 part, Rhizoma Chuanxiong 3-9 part, Radix Paeoniae Rubra 3-9 part, Radix Notoginseng 3-9 part.
The Chinese medicine composition of described treatment liver cirrhosis, is made up of the crude drug of following weight portion: the Radix Astragali 30 parts, Radix Salviae Miltiorrhizae 30 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Rhizoma Imperatae 30 parts, the Radix Paeoniae Alba 20 parts, 20 parts, Rhizoma Curcumae Longae, Herba Artemisiae Scopariae 20 parts, Radix Isatidis 20 parts, 15 parts, Poria, Radix Codonopsis 15 parts, Semen Plantaginis 15 parts, Herba Leonuri 15 parts, Herba Sedi 15 parts, Herba Hedyotidis Diffusae 15 parts, Herba Verbenae 15 parts, Herba Lycopi 10 parts, Rhizoma Curcumae 10 parts, Pheretima 10 parts, Semen Plantaginis 10 parts, Semen Arecae 10 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Alismatis 10 parts, Endothelium Corneum Gigeriae Galli 10 parts, 6 parts, Flos Carthami, Rhizoma Chuanxiong 6 parts, Radix Paeoniae Rubra 6 parts, Radix Notoginseng 6 parts.
The preparation method of the Chinese medicine composition of described treatment liver cirrhosis is: make decoction, concentrated pill or concentrated capsule according to a conventional method by described Chinese medicine composition.
Usage and consumption: Chinese medicine composition of the present invention is based on decoction, and every day 1 pair, divide and take for 2 times, early, respectively take 1 time evening, within 30 days, be 1 course for the treatment of, general 1-4 can cure a course for the treatment of; Also concentrated pill or concentrated capsule can be made into.
The beneficial effect that the present invention is compared with prior art had is: the present invention is under Traditional Chinese medical theory and clinical experience instruct, choose each crude drug and proportioning thereof, there is invigorating the spleen and benefiting QI, inducing diuresis to remove edema, nourish blood soothing the liver function, realize the object for the treatment of liver cirrhosis; The advantage such as the present invention has evident in efficacy, instant effect, has no side effect, preparation method is simple, through clinical verification, it is 95% that the present invention treats liver cirrhosis effective percentage.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine composition for liver cirrhosis, be made up of the crude drug of following weight portion: the Radix Astragali 30 parts, Radix Salviae Miltiorrhizae 30 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Rhizoma Imperatae 30 parts, the Radix Paeoniae Alba 20 parts, 20 parts, Rhizoma Curcumae Longae, Herba Artemisiae Scopariae 20 parts, Radix Isatidis 20 parts, 15 parts, Poria, Radix Codonopsis 15 parts, Semen Plantaginis 15 parts, Herba Leonuri 15 parts, Herba Sedi 15 parts, Herba Hedyotidis Diffusae 15 parts, Herba Verbenae 15 parts, Herba Lycopi 10 parts, Rhizoma Curcumae 10 parts, Pheretima 10 parts, Semen Plantaginis 10 parts, Semen Arecae 10 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Alismatis 10 parts, Endothelium Corneum Gigeriae Galli 10 parts, 6 parts, Flos Carthami, Rhizoma Chuanxiong 6 parts, Radix Paeoniae Rubra 6 parts, Radix Notoginseng 6 parts.
The preparation method of the Chinese medicine composition of described treatment liver cirrhosis is: make decoction, concentrated pill or concentrated capsule according to a conventional method by described Chinese medicine composition.
Embodiment 2:
Treat a Chinese medicine composition for liver cirrhosis, be made up of the crude drug of following weight portion: the Radix Astragali 25 parts, Radix Salviae Miltiorrhizae 25 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Rhizoma Imperatae 25 parts, the Radix Paeoniae Alba 15 parts, 15 parts, Rhizoma Curcumae Longae, Herba Artemisiae Scopariae 15 parts, Radix Isatidis 15 parts, 10 parts, Poria, Radix Codonopsis 10 parts, Semen Plantaginis 10 parts, Herba Leonuri 10 parts, Herba Sedi 10 parts, Herba Hedyotidis Diffusae 10 parts, Herba Verbenae 10 parts, Herba Lycopi 5 parts, Rhizoma Curcumae 5 parts, Pheretima 5 parts, Semen Plantaginis 5 parts, Semen Arecae 5 parts, Radix Angelicae Sinensis 5 parts, Rhizoma Alismatis 5 parts, Endothelium Corneum Gigeriae Galli 5 parts, 3 parts, Flos Carthami, Rhizoma Chuanxiong 3 parts, Radix Paeoniae Rubra 3 parts, Radix Notoginseng 3 parts.
The preparation method of the Chinese medicine composition of described treatment liver cirrhosis is: make decoction, concentrated pill or concentrated capsule according to a conventional method by described Chinese medicine composition.
Embodiment 3:
Treat a Chinese medicine composition for liver cirrhosis, be made up of the crude drug of following weight portion: the Radix Astragali 35 parts, Radix Salviae Miltiorrhizae 35 parts, the Rhizoma Atractylodis Macrocephalae 35 parts, Rhizoma Imperatae 35 parts, the Radix Paeoniae Alba 25 parts, 25 parts, Rhizoma Curcumae Longae, Herba Artemisiae Scopariae 25 parts, Radix Isatidis 25 parts, 20 parts, Poria, Radix Codonopsis 20 parts, Semen Plantaginis 20 parts, Herba Leonuri 20 parts, Herba Sedi 20 parts, Herba Hedyotidis Diffusae 20 parts, Herba Verbenae 20 parts, Herba Lycopi 15 parts, Rhizoma Curcumae 15 parts, Pheretima 15 parts, Semen Plantaginis 15 parts, Semen Arecae 15 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Alismatis 15 parts, Endothelium Corneum Gigeriae Galli 15 parts, 9 parts, Flos Carthami, Rhizoma Chuanxiong 9 parts, Radix Paeoniae Rubra 9 parts, Radix Notoginseng 9 parts.
The preparation method of the Chinese medicine composition of described treatment liver cirrhosis is: make decoction, concentrated pill or concentrated capsule according to a conventional method by described Chinese medicine composition.
Experimental example:
(1) clinical data: the present invention treat altogether liver cirrhosis patient 40 example, wherein man 24 example, female 16 example, the age be 25-65 year.
(2) Therapeutic Method: Chinese medicine composition of the present invention is based on decoction, and every day 1 pair, divide and take for 2 times, early, evening respectively takes 1 time, 30 days is 1 course for the treatment of; Also concentrated pill or concentrated capsule can be made into.
(3) the standard of curative effect evaluation:
Cure: clinical symptom disappearance, ascites absorption is complete, and liver function recovery is normal;
Effective: clinical symptom disappearance, ascites basic absorption is complete, and liver function recovery is normal;
Effective: clinical symptoms disappears substantially, more than ascites absorption >70%, liver function is close to normal;
Invalid: clinical symptoms, ascites and liver function are all not improved.
(4) therapeutic outcome: the present invention treats liver cirrhosis patient 40 example altogether, through the treatment of 1-4 the course for the treatment of, cures 24 examples, accounts for 60%, and effective 10 examples, account for 25%, and effective 4 examples, account for 10%, and invalid 2 examples, account for 5%, effective percentage is 95%.
(5) model case:
1, Zhao, man, 47 years old, suffers from chronic hepatitis history 8 years, abdominal distention, limb is swollen, oliguria January, cardinal symptom is that complexion is black dull, the visible spider angioma of cervical region, abdominal distention, ascites ++, lower 1 centimetre of liver rib, lower 4 centimetres of xiphoid-process, reset 90 centimetres, light red tongue, thick, yellow and greasy fur, deep-thready pulse.Liver function: ALT60u, HBSAG are negative, A37 gram/L, RBC2.5 × 10 12/ L, WBC45 × 10 9/ L, PC46 × 10 9/ L.Ultrasound diagnosis: hepatosplenomegaly, liver cirrhosis, ascites; Cure after taking 4 courses for the treatment of of Chinese medicine composition of the present invention.
2, history so-and-so, female, 41 years old, suffers from chronic hepatopathy 12 years, liver cirrhosis 4 years, cardinal symptom is dim complexion, weak, poor appetite, feel sick, abdominal distention.Ultrasound diagnosis: lower 5 centimetres of liver sword, lower 3 centimetres of rib, splenomegaly.Cure after taking 3 courses for the treatment of of Chinese medicine composition of the present invention.

Claims (3)

1. treat the Chinese medicine composition of liver cirrhosis for one kind, it is characterized in that: be made up of the crude drug of following weight portion: Radix Astragali 25-35 part, Radix Salviae Miltiorrhizae 25-35 part, Rhizoma Atractylodis Macrocephalae 25-35 part, Rhizoma Imperatae 25-35 part, Radix Paeoniae Alba 15-25 part, Rhizoma Curcumae Longae 15-25 part, Herba Artemisiae Scopariae 15-25 part, Radix Isatidis 15-25 part, Poria 10-20 part, Radix Codonopsis 10-20 part, Semen Plantaginis 10-20 part, Herba Leonuri 10-20 part, Herba Sedi 10-20 part, Herba Hedyotidis Diffusae 10-20 part, Herba Verbenae 10-20 part, Herba Lycopi 5-15 part, Rhizoma Curcumae 5-15 part, Pheretima 5-15 part, Semen Plantaginis 5-15 part, Semen Arecae 5-15 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Alismatis 5-15 part, Endothelium Corneum Gigeriae Galli 5-15 part, Flos Carthami 3-9 part, Rhizoma Chuanxiong 3-9 part, Radix Paeoniae Rubra 3-9 part, Radix Notoginseng 3-9 part.
2. the Chinese medicine composition for the treatment of liver cirrhosis according to claim 1, it is characterized in that: be made up of the crude drug of following weight portion: the Radix Astragali 30 parts, Radix Salviae Miltiorrhizae 30 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Rhizoma Imperatae 30 parts, the Radix Paeoniae Alba 20 parts, 20 parts, Rhizoma Curcumae Longae, Herba Artemisiae Scopariae 20 parts, Radix Isatidis 20 parts, 15 parts, Poria, Radix Codonopsis 15 parts, Semen Plantaginis 15 parts, Herba Leonuri 15 parts, Herba Sedi 15 parts, Herba Hedyotidis Diffusae 15 parts, Herba Verbenae 15 parts, Herba Lycopi 10 parts, Rhizoma Curcumae 10 parts, Pheretima 10 parts, Semen Plantaginis 10 parts, Semen Arecae 10 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Alismatis 10 parts, Endothelium Corneum Gigeriae Galli 10 parts, 6 parts, Flos Carthami, Rhizoma Chuanxiong 6 parts, Radix Paeoniae Rubra 6 parts, Radix Notoginseng 6 parts.
3. the preparation method of the Chinese medicine composition for the treatment of liver cirrhosis according to claim 1 and 2, is characterized in that: make decoction, concentrated pill or concentrated capsule according to a conventional method by Chinese medicine composition described in claim 1 or 2.
CN201310293192.5A 2013-07-13 2013-07-13 Traditional Chinese medicine composition for treating liver cirrhosis and preparation method thereof Expired - Fee Related CN103316305B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103638472A (en) * 2013-12-03 2014-03-19 宋文琴 Traditional Chinese medicine decoction for treating primary biliary cirrhosis
CN104971147A (en) * 2015-08-06 2015-10-14 杨国顺 Traditional Chinese medicine composition for treating liver cirrhosis and liver ascites and preparation method thereof
CN105456517A (en) * 2015-12-15 2016-04-06 彭国能 Traditional Chinese medicinal composition and preparation for treating chronic hepatitis B and preparation method of preparation
CN107397776A (en) * 2017-09-05 2017-11-28 林树芳 A kind of Chinese medicine composition for treating disease in the liver and gallbladder and preparation method thereof
CN108653669A (en) * 2018-06-24 2018-10-16 熊明彬 A kind of Chinese medicine preparation that can treat hepatic sclerosis

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1058163C (en) * 1995-06-02 2000-11-08 丁殿利 Yigan Kangyangsan powder for curing hepatitis B
CN101024061A (en) * 2006-02-18 2007-08-29 陈晓辉 Medicine for interally and externally treating liver cirrhosis
CN101185747A (en) * 2007-10-17 2008-05-28 门连社 Prescription for treating hepatic disease

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Inventor after: Dong Zeqing

Inventor after: Liu Dewen

Inventor after: Wei Fei

Inventor before: Hua Ju

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Address after: 262700, 7, LV Lu, stay Town, Shouguang City, Shandong, Weifang

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Address before: Mei Hua Wei Huaishang district town 233000 administrative villages in Anhui province Bengbu City, No. 57 Hua Wei

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