CN103316305A - Traditional Chinese medicine composition for treating liver cirrhosis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating liver cirrhosis and preparation method thereof Download PDF

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Publication number
CN103316305A
CN103316305A CN2013102931925A CN201310293192A CN103316305A CN 103316305 A CN103316305 A CN 103316305A CN 2013102931925 A CN2013102931925 A CN 2013102931925A CN 201310293192 A CN201310293192 A CN 201310293192A CN 103316305 A CN103316305 A CN 103316305A
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radix
herba
rhizoma
chinese medicine
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CN103316305B (en
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华菊
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Dong Zeqing
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Abstract

The invention relates to a traditional Chinese medicine composition for treating liver cirrhosis and a preparation method thereof. The composition is prepared from the following bulk drugs: milkvetch root, red sage root, bighead atractylodes rhizome, imperata rhizome, white peony root, turmeric, virgate wormwood herb, isatis root, Poria cocos, dangshen, Plantain seed, motherwort, stringy stonecrop herb, heydyotis, verbena, Japanese eupatorium, curcuma rhizome, earthworm, Plantain seed, betel nut, Chinese angelica, oriental waterplantain rhizome, chicken's gizzard membrane, safflower, Sichuan lovage rhizome, red peony root and pseudo-ginseng. The invention has the following advantages: the traditional Chinese medicine composition has a substantial curative effect, fast action and no toxic and side effects; the preparation method is simple; etc.

Description

A kind of Chinese medicine composition for the treatment of liver cirrhosis and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine composition for the treatment of liver cirrhosis and preparation method thereof.
Background technology
Liver cirrhosis refers to because different pathogeny long-term damage livers such as virus, malnutrition due to parasitic infestation, food and drink or medicines, cause hepatocellular degeneration, necrosis, regeneration, extensively proliferation of fibrous tissue causes the irreversible change of liver structure gradually, and is hard with the right flank distending pain, nauseating poor appetite, fatigue and weakness, angry of abdomen muscle, the red thread of red filament, purplish tongue is dark, and stringy pulse is the chronic hepatopathy of main manifestations.Liver cirrhosis is divided into clinically the compensatory phase and loses the compensatory phase.Can there be the hepatitis clinical manifestation the compensatory phase, and the slightly symptom such as weak, abdominal distention also can be arranged.Lose the compensatory phase then take liver function damage and portal hypertension as main manifestations, also can have weak, become thin, the symptoms such as dim complexion, oliguria, edema of lower limbs, abdominal distention.
At present, the medicine that is used for the treatment of liver cirrhosis is more, but there are the deficiencies such as therapeutic effect is relatively poor, treatment time is long, side effect is large in it.
Summary of the invention
The technical problem to be solved in the present invention is: for solving the deficiencies in the prior art, the invention provides a kind of Chinese medicine composition for the treatment of liver cirrhosis and preparation method thereof, that the present invention has is evident in efficacy, instant effect, have no side effect, the advantage such as preparation method is simple.
A kind of Chinese medicine composition for the treatment of liver cirrhosis is made by the crude drug of following weight portion: Radix Astragali 25-35 part, Radix Salviae Miltiorrhizae 25-35 part, Rhizoma Atractylodis Macrocephalae 25-35 part, Rhizoma Imperatae 25-35 part, Radix Paeoniae Alba 15-25 part, Rhizoma Curcumae Longae 15-25 part, Herba Artemisiae Scopariae 15-25 part, Radix Isatidis 15-25 part, Poria 10-20 part, Radix Codonopsis 10-20 part, Semen Plantaginis 10-20 part, Herba Leonuri 10-20 part, Herba Sedi 10-20 part, Herba Hedyotidis Diffusae 10-20 part, Herba Verbenae 10-20 part, Herba Lycopi 5-15 part, Rhizoma Curcumae 5-15 part, Pheretima 5-15 part, Semen Plantaginis 5-15 part, Semen Arecae 5-15 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Alismatis 5-15 part, Endothelium Corneum Gigeriae Galli 5-15 part, Flos Carthami 3-9 part, Rhizoma Chuanxiong 3-9 part, Radix Paeoniae Rubra 3-9 part, Radix Notoginseng 3-9 part.
The Chinese medicine composition of described treatment liver cirrhosis is made by the crude drug of following weight portion: 30 parts of the Radixs Astragali, 30 parts of Radix Salviae Miltiorrhizaes, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Imperataes, 20 parts of the Radix Paeoniae Albas, 20 parts in Rhizoma Curcumae Longae, 20 parts of Herba Artemisiae Scopariaes, 20 parts of Radix Isatidis, 15 parts in Poria, 15 parts of Radix Codonopsis, 15 parts of Semen Plantaginiss, 15 parts of Herba Leonuris, 15 parts of Herba Sedis, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Herba Verbenae, 10 parts of Herba Lycopi, 10 parts of Rhizoma Curcumae, 10 parts of Pheretimas, 10 parts of Semen Plantaginiss, 10 parts of Semen Arecaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Alismatis, 10 parts of Endothelium Corneum Gigeriae Galli, 6 parts on Flos Carthami, 6 parts of Rhizoma Chuanxiongs, 6 parts of Radix Paeoniae Rubra, 6 parts of Radix Notoginseng.
The preparation method of the Chinese medicine composition of described treatment liver cirrhosis is: make according to a conventional method decoction, concentrated pill or concentrated capsule by described Chinese medicine composition.
Usage and consumption: Chinese medicine composition of the present invention is take decoction as main, takes 1 pair of every day minutes for 2 times, and early, respectively take 1 time evening, 30 days is 1 course for the treatment of, and can cure general 1-4 course for the treatment of; Also can be made into concentrated pill or concentrated capsule.
The beneficial effect that the present invention compared with prior art has is: the present invention is under Traditional Chinese medical theory and clinical experience guidance, choose each crude drug and proportioning thereof, have invigorating the spleen and benefiting QI, inducing diuresis to remove edema, the soothing the liver function that nourishes blood, realize the purpose for the treatment of liver cirrhosis; That the present invention has is evident in efficacy, instant effect, have no side effect, the advantage such as preparation method is simple, through clinical verification, it is 95% that the present invention treats the liver cirrhosis effective percentage.
The specific embodiment
Embodiment 1:
A kind of Chinese medicine composition for the treatment of liver cirrhosis is made by the crude drug of following weight portion: 30 parts of the Radixs Astragali, 30 parts of Radix Salviae Miltiorrhizaes, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Imperataes, 20 parts of the Radix Paeoniae Albas, 20 parts in Rhizoma Curcumae Longae, 20 parts of Herba Artemisiae Scopariaes, 20 parts of Radix Isatidis, 15 parts in Poria, 15 parts of Radix Codonopsis, 15 parts of Semen Plantaginiss, 15 parts of Herba Leonuris, 15 parts of Herba Sedis, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Herba Verbenae, 10 parts of Herba Lycopi, 10 parts of Rhizoma Curcumae, 10 parts of Pheretimas, 10 parts of Semen Plantaginiss, 10 parts of Semen Arecaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Alismatis, 10 parts of Endothelium Corneum Gigeriae Galli, 6 parts on Flos Carthami, 6 parts of Rhizoma Chuanxiongs, 6 parts of Radix Paeoniae Rubra, 6 parts of Radix Notoginseng.
The preparation method of the Chinese medicine composition of described treatment liver cirrhosis is: make according to a conventional method decoction, concentrated pill or concentrated capsule by described Chinese medicine composition.
Embodiment 2:
A kind of Chinese medicine composition for the treatment of liver cirrhosis is made by the crude drug of following weight portion: 25 parts of the Radixs Astragali, 25 parts of Radix Salviae Miltiorrhizaes, 25 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts of Rhizoma Imperataes, 15 parts of the Radix Paeoniae Albas, 15 parts in Rhizoma Curcumae Longae, 15 parts of Herba Artemisiae Scopariaes, 15 parts of Radix Isatidis, 10 parts in Poria, 10 parts of Radix Codonopsis, 10 parts of Semen Plantaginiss, 10 parts of Herba Leonuris, 10 parts of Herba Sedis, 10 parts of Herba Hedyotidis Diffusaes, 10 parts of Herba Verbenae, 5 parts of Herba Lycopi, 5 parts of Rhizoma Curcumae, 5 parts of Pheretimas, 5 parts of Semen Plantaginiss, 5 parts of Semen Arecaes, 5 parts of Radix Angelicae Sinensis, 5 parts of Rhizoma Alismatis, 5 parts of Endothelium Corneum Gigeriae Galli, 3 parts on Flos Carthami, 3 parts of Rhizoma Chuanxiongs, 3 parts of Radix Paeoniae Rubra, 3 parts of Radix Notoginseng.
The preparation method of the Chinese medicine composition of described treatment liver cirrhosis is: make according to a conventional method decoction, concentrated pill or concentrated capsule by described Chinese medicine composition.
Embodiment 3:
A kind of Chinese medicine composition for the treatment of liver cirrhosis is made by the crude drug of following weight portion: 35 parts of the Radixs Astragali, 35 parts of Radix Salviae Miltiorrhizaes, 35 parts of the Rhizoma Atractylodis Macrocephalaes, 35 parts of Rhizoma Imperataes, 25 parts of the Radix Paeoniae Albas, 25 parts in Rhizoma Curcumae Longae, 25 parts of Herba Artemisiae Scopariaes, 25 parts of Radix Isatidis, 20 parts in Poria, 20 parts of Radix Codonopsis, 20 parts of Semen Plantaginiss, 20 parts of Herba Leonuris, 20 parts of Herba Sedis, 20 parts of Herba Hedyotidis Diffusaes, 20 parts of Herba Verbenae, 15 parts of Herba Lycopi, 15 parts of Rhizoma Curcumae, 15 parts of Pheretimas, 15 parts of Semen Plantaginiss, 15 parts of Semen Arecaes, 15 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Alismatis, 15 parts of Endothelium Corneum Gigeriae Galli, 9 parts on Flos Carthami, 9 parts of Rhizoma Chuanxiongs, 9 parts of Radix Paeoniae Rubra, 9 parts of Radix Notoginseng.
The preparation method of the Chinese medicine composition of described treatment liver cirrhosis is: make according to a conventional method decoction, concentrated pill or concentrated capsule by described Chinese medicine composition.
Experimental example:
(1) clinical data: the present invention treats liver cirrhosis patient 40 examples altogether, male 24 examples wherein, and women 16 examples, the age is 25-65 year.
(2) Therapeutic Method: Chinese medicine composition of the present invention is take decoction as main, takes 1 pair of every day minutes for 2 times, and early, respectively take 1 time evening, 30 days is 1 course for the treatment of; Also can be made into concentrated pill or concentrated capsule.
(3) the standard of curative effect evaluation:
Cure: clinical symptom disappearance, ascites absorption is complete, and liver function recovery is normal;
Produce effects: clinical symptom disappearance, the ascites basic absorption is complete, and liver function recovery is normal;
Effectively: clinical symptoms disappears substantially, ascites absorption〉more than 70%, liver function approaches normal;
Invalid: clinical symptoms, ascites and liver function are all without obviously improving.
(4) therapeutic outcome: the present invention treats liver cirrhosis patient 40 examples altogether, through the treatment of 1-4 the course for the treatment of, cures 24 examples, accounts for 60%, and produce effects 10 examples account for 25%, and effective 4 examples account for 10%, and invalid 2 examples account for 5%, and effective percentage is 95%.
(5) model case:
1, Zhao, the man, 47 years old, suffered from the chronic hepatitis history 8 years, abdominal distention, limb are swollen, oliguria January, cardinal symptom is that complexion is black dull, the visible spider angioma of cervical region, abdominal distention, ascites ++, lower 1 centimetre of liver rib, lower 4 centimetres of xiphoid-process, reset 90 centimetres, light red tongue, thick, yellow and greasy fur, deep-thready pulse.Liver function: ALT60u, HBSAG is negative, A37 gram/L, RBC2.5 * 10 12/ L, WBC45 * 10 9/ L, PC46 * 10 9/ L.Ultrasound diagnosis: hepatosplenomegaly, liver cirrhosis, ascites; Taking Chinese medicine composition of the present invention cured after 4 courses for the treatment of.
2, history so-and-so, the woman, 41 years old, suffered from chronic hepatopathy 12 years, liver cirrhosis 4 years, cardinal symptom is dim complexion, weak, poor appetite, feel sick, abdominal distention.Ultrasound diagnosis: lower 5 centimetres of liver sword, lower 3 centimetres of rib, splenomegaly.Taking Chinese medicine composition of the present invention cured after 3 courses for the treatment of.

Claims (3)

1. Chinese medicine composition for the treatment of liver cirrhosis, it is characterized in that: the crude drug by following weight portion is made: Radix Astragali 25-35 part, Radix Salviae Miltiorrhizae 25-35 part, Rhizoma Atractylodis Macrocephalae 25-35 part, Rhizoma Imperatae 25-35 part, Radix Paeoniae Alba 15-25 part, Rhizoma Curcumae Longae 15-25 part, Herba Artemisiae Scopariae 15-25 part, Radix Isatidis 15-25 part, Poria 10-20 part, Radix Codonopsis 10-20 part, Semen Plantaginis 10-20 part, Herba Leonuri 10-20 part, Herba Sedi 10-20 part, Herba Hedyotidis Diffusae 10-20 part, Herba Verbenae 10-20 part, Herba Lycopi 5-15 part, Rhizoma Curcumae 5-15 part, Pheretima 5-15 part, Semen Plantaginis 5-15 part, Semen Arecae 5-15 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Alismatis 5-15 part, Endothelium Corneum Gigeriae Galli 5-15 part, Flos Carthami 3-9 part, Rhizoma Chuanxiong 3-9 part, Radix Paeoniae Rubra 3-9 part, Radix Notoginseng 3-9 part.
2. the Chinese medicine composition for the treatment of liver cirrhosis according to claim 1, it is characterized in that: the crude drug by following weight portion is made: 30 parts of the Radixs Astragali, 30 parts of Radix Salviae Miltiorrhizaes, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Imperataes, 20 parts of the Radix Paeoniae Albas, 20 parts in Rhizoma Curcumae Longae, 20 parts of Herba Artemisiae Scopariaes, 20 parts of Radix Isatidis, 15 parts in Poria, 15 parts of Radix Codonopsis, 15 parts of Semen Plantaginiss, 15 parts of Herba Leonuris, 15 parts of Herba Sedis, 15 parts of Herba Hedyotidis Diffusaes, 15 parts of Herba Verbenae, 10 parts of Herba Lycopi, 10 parts of Rhizoma Curcumae, 10 parts of Pheretimas, 10 parts of Semen Plantaginiss, 10 parts of Semen Arecaes, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Alismatis, 10 parts of Endothelium Corneum Gigeriae Galli, 6 parts on Flos Carthami, 6 parts of Rhizoma Chuanxiongs, 6 parts of Radix Paeoniae Rubra, 6 parts of Radix Notoginseng.
3. the preparation method of the Chinese medicine composition for the treatment of liver cirrhosis according to claim 1 and 2 is characterized in that: make according to a conventional method decoction, concentrated pill or concentrated capsule by claim 1 or 2 described Chinese medicine compositions.
CN201310293192.5A 2013-07-13 2013-07-13 Traditional Chinese medicine composition for treating liver cirrhosis and preparation method thereof Expired - Fee Related CN103316305B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103638472A (en) * 2013-12-03 2014-03-19 宋文琴 Traditional Chinese medicine decoction for treating primary biliary cirrhosis
CN104971147A (en) * 2015-08-06 2015-10-14 杨国顺 Traditional Chinese medicine composition for treating liver cirrhosis and liver ascites and preparation method thereof
CN105456517A (en) * 2015-12-15 2016-04-06 彭国能 Traditional Chinese medicinal composition and preparation for treating chronic hepatitis B and preparation method of preparation
CN107397776A (en) * 2017-09-05 2017-11-28 林树芳 A kind of Chinese medicine composition for treating disease in the liver and gallbladder and preparation method thereof
CN108653669A (en) * 2018-06-24 2018-10-16 熊明彬 A kind of Chinese medicine preparation that can treat hepatic sclerosis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137383A (en) * 1995-06-02 1996-12-11 丁殿利 Yigan Kangyangsan powder for curing hepatitis B
CN101024061A (en) * 2006-02-18 2007-08-29 陈晓辉 Medicine for interally and externally treating liver cirrhosis
CN101185747A (en) * 2007-10-17 2008-05-28 门连社 Prescription for treating hepatic disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137383A (en) * 1995-06-02 1996-12-11 丁殿利 Yigan Kangyangsan powder for curing hepatitis B
CN101024061A (en) * 2006-02-18 2007-08-29 陈晓辉 Medicine for interally and externally treating liver cirrhosis
CN101185747A (en) * 2007-10-17 2008-05-28 门连社 Prescription for treating hepatic disease

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103638472A (en) * 2013-12-03 2014-03-19 宋文琴 Traditional Chinese medicine decoction for treating primary biliary cirrhosis
CN104971147A (en) * 2015-08-06 2015-10-14 杨国顺 Traditional Chinese medicine composition for treating liver cirrhosis and liver ascites and preparation method thereof
CN105456517A (en) * 2015-12-15 2016-04-06 彭国能 Traditional Chinese medicinal composition and preparation for treating chronic hepatitis B and preparation method of preparation
CN107397776A (en) * 2017-09-05 2017-11-28 林树芳 A kind of Chinese medicine composition for treating disease in the liver and gallbladder and preparation method thereof
CN108653669A (en) * 2018-06-24 2018-10-16 熊明彬 A kind of Chinese medicine preparation that can treat hepatic sclerosis

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Inventor after: Dong Zeqing

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