CN103041228A - Traditional Chinese medicine composite for treating myasthenia gravis - Google Patents
Traditional Chinese medicine composite for treating myasthenia gravis Download PDFInfo
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- CN103041228A CN103041228A CN2013100212265A CN201310021226A CN103041228A CN 103041228 A CN103041228 A CN 103041228A CN 2013100212265 A CN2013100212265 A CN 2013100212265A CN 201310021226 A CN201310021226 A CN 201310021226A CN 103041228 A CN103041228 A CN 103041228A
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Abstract
The invention relates to traditional Chinese medicine composite for treating myasthenia gravis. The traditional Chinese medicine composite for treating the myasthenia gravis is characterized by being prepared from the following raw medicines in parts by weight: 8-10g astragalus root, 6-9g lucid ganoderma, 4-6g angelica sinensis, 6-9g radix paeoniae alba, 6-8g gastrodia elata, 4-6g safflower, 6-9g rhizoma chuanxiong, 2-4g pseudo-ginseng, 6-9g the root of red-rooted salvia, 6-9g rhizoma cyperi, 6-10g prepared rehmannia root, 6-9g cortex acanthopanacis, 4-6g oldenlandia diffusa, 8-10g Caulis Spatholobi, 6-10g kadsura pepper stem, 6-9g loranthus parasiticus, 6-9g American ginseng, 8-10g semen coicis and 6-9g liquorice. The traditional Chinese medicine composite for treating the myasthenia gravis disclosed by the invention has the beneficial effects of promoting qi to activate blood, nourishing liver and kidney, strengthening tendons and bones, and nursing skin, and also has the advantages of good effect, high cure rate and low toxic and side effects.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition of myasthenia gravis.
As everyone knows, myasthenia gravis (myasthenia gravis, MG) is a kind of autoimmune disease that mainly involves acetylcholinergic receptor on the neuromuscular junction postsynaptic membrane (acetylcholine receptor, AchR).The traditional Chinese medical science claims " disease of withering ".The qi stagnation and blood stasis types that belong to the traditional Chinese medical science make muscles and bones, muscle can not get moistening foster more.Clinical main manifestations is part or whole body skeleton myasthenia and fatiguability, and movable rear sx↑ is through having a rest and cholinesterase inhibitor sx↓ after the treatment.Any age from the neonate to old people all can fall ill.Women's onset peak was at 20～30 years old, and the male merged thymoma at 50～60 years old more.Small number of patients has family history.The onset concealment, the whole course of disease has fluctuation, alleviates with recurrence to replace.Should and easily repeatedly reach uncertain morbidity, it is unfavorable that the patient is brought.
Summary of the invention
The beneficial effect of Chinese traditional treatment primary disease is: promoting flow of QI and blood, nourishing liver and kidney, bone and muscle strengthening, moisten health preserving flesh.Clinically often according to the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of different disease type.
Technical problem to be solved by this invention is in order to overcome technical deficiency, a kind of good effect, short treating period to be provided, and remission rate is high, and cost is low, a kind of Chinese medicine composition for the treatment of myasthenia gravis that has no side effect.
For above-mentioned purpose, a kind of Chinese medicine composition for the treatment of myasthenia gravis is characterized in that its raw material medicines in portions by weight is as follows: the Radix Astragali 8～10g, Ganoderma 6～9g, Radix Angelicae Sinensis 4～6g, the Radix Paeoniae Alba 6～9g, Rhizoma Gastrodiae 6～8g, Flos Carthami 4～6g, Rhizoma Chuanxiong 6～9g, Radix Notoginseng 2～4g, Radix Salviae Miltiorrhizae 6～9g, Rhizoma Cyperi 6～9g, Radix Rehmanniae Preparata 6～10g, Fructus Corni 6～9g, Cortex Acanthopancis 6～9g, Herba Hedyotidis Diffusae 4～6g, Caulis Spatholobi 8～10g, Caulis Piperis Kadsurae 6～10g, Herba Taxilli 6～9g, Radix Panacis Quinquefolii 6～9g, Semen Coicis 8～10g, Radix Glycyrrhizae 6～9g.
The Radix Astragali sweet in the mouth of Chinese medicine of the present invention, slightly warm in nature.Return lung, spleen, liver, kidney channel.Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Reuse, the vigour of large tonifying the spleen and stomach makes the prosperous blood of gas, and the stasis of blood is removed ruton.Modern study, rat oral gavage Astragalus membranaceus 6 days or 14 days can strengthen the fatigue proof effect of rats'swimming, and Suppressor cells rat plasma Determination of cortisol is obviously increased.The Ganoderma feeble QI is fragrant, bitter and puckery flavor.GUIXIN, liver, spleen, lung, the kidney Five Classics.The Ganoderma tool is calmed the nerves, stomach invigorating, the effect of removing expectorant, invigorating blood circulation.Have the adjusting immune level with Radix Astragali compatibility, alleviate bronchospasm, and significant expectoration effect.Radix Angelicae Sinensis sweet in the mouth, suffering, hardship, warm in nature.Return liver, the heart, spleen channel.Effect: enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.Cure mainly: all cards of blood deficiency, lump in the abdomen knot is poly-, flaccidity syndrome and arthralgia syndrome, numbness of the skin ...The acid of Radix Paeoniae Alba bitter in the mouth, cool in nature.Enter liver, spleen channel.Function cures mainly: nourishing blood to suppress the hyperactive liver, and slow middle pain relieving, yin fluid astringing is received antiperspirant." not Lu ": " clear and coherent blood vessels, slow in, dispelling malignant blood, expelling extravasated blood, the gas that anhydrates, sharp bladder, intestine and small intestine, subduing inflammation, row cold and heat when (controlling), attacked by pestiferous factors stomachache, lumbago." modern study, the effect with hepatoprotective, antiinflammatory, enhancing human body immunity power.Rhizoma Gastrodiae is sweet flat, returns Liver Channel.Effect: endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral." property of medicine opinion ": control the cold air insensitive impediment, paralysis is slow unsuccessful, and how in a trance speak, and shies mental confusion more.Herba Hedyotidis Diffusae sweet in the mouth, light, cool in nature.Enter the heart, liver, spleen channel.Function cures mainly: heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, inducing diuresis to remove edema.Be used for laryngopharynx swelling and pain, dyspnea and cough due to lung-heat, the puckery pain of pyretic stranguria, jaundice due to damp-heat, venom, the skin ulcer hot carbuncle that swells.Modern study has that antitumor is antibiotic, the effect of antiinflammatory.The Flos Carthami function cures mainly: promoting blood circulation to restore menstrual flow, loose silt pain relieving." detailed outline ": invigorate blood circulation, moisturize, pain relieving, loose swollen, stimulate the menstrual flow.Modern study has the blood circulation of improvement, strengthens the effect of immunity.The Rhizoma Chuanxiong acrid in the mouth, perfume (or spice) warm in nature is dry, walks and does not keep, can go loose, the up top, mountain peak that reaches; Enter again blood system, the descending sea of blood that reaches.The blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various diseases of stagnation of blood stasis." detailed outline ": dampness, antidiarrheal dysentery, activating QI to alleviate the depression.Rhizome of chuanxiong Qiong, in the blood gas medicine also, liver is bitter anxious mends it with suffering, so blood deficiency person should it; Hot to fall apart it, so stagnation of QI person should it.Radix Notoginseng sweet in the mouth, little hardship, warm in nature.Return liver stomach cardiopulmonary warp, large intestine channel.Function cures mainly: hemostasis, loose blood, analgesic therapy.Be not taken by pregnant women." " beautiful Chinese catalpa medicine solution " cloud: " Radix Notoginseng and battalion hemostasis, the clots absorbing of promoting blood circulation, clots absorbing blood and hold back fresh blood." the Radix Salviae Miltiorrhizae bitter in the mouth, cold nature.Function cures mainly: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind." detailed outline ": invigorate blood circulation logical percardium.The Rhizoma Cyperi sweet in the mouth is slightly cold, and property is flat, and is nontoxic.Function cures mainly: the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving." book on Chinese herbal medicine is stated ": this circulation of qi promoting in blood of distinguishing the flavor of, then blood with and give birth to, blood with and give birth to, then gas to some extent according to and strong fortune is not poor, the meaning hemopoietic that is, the meaning QI invigorating that is, non-ambiguous is also.The Radix Rehmanniae Preparata sweet in the mouth, warm in nature.Return the Liver and kidney warp.Function cures mainly: moist, the beneficial essence of enriching blood is filled out marrow.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, soreness of the waist and knees ..." detailed outline ": fill out bone marrow, longue meat, promoting generation of vital essence and blood, tonifying five ZANG-organs, internal injury deficiency, promoting blood circulation, sharp knowledge, black beard and hair.Fructus Corni sour in the mouth, property are puckery, tepor.Return liver, kidney channel.Function cures mainly: liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating.Be used for deficiency of the liver and kindey, have a dizzy spell tinnitus, the soreness of waist., " not Lu ": " the reinforcing YIN-essence benefit is smart, An Wuzang, logical nine orifices ends normal urination." Cortex Acanthopancis acrid in the mouth, hardship, warm in nature.Return liver, kidney channel.Function cures mainly: wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, the arteries and veins of invigorating blood circulation.Caulis Spatholobi bitter in the mouth, sweet, warm in nature.Return liver, kidney channel.Function cures mainly: endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Caulis Piperis Kadsurae acrid in the mouth, hardship, slightly warm in nature.Return Liver Channel.Function cures mainly: wind-damp dispelling, the meridian dredging, stopping numbness pain.Radix Panacis Quinquefolii sweet in the mouth, little hardship, cool in nature.GUIXIN, lung, kidney channel.Function cures mainly: boosting qi and nourishing yin, clearing away heat and promoting production of body fluid." property of medicine is examined ": nourishing YIN is brought down a fever.The processed with Rhizoma Zingiberis Recens QI invigorating, righting gas.Herba Taxilli bitter in the mouth, sweet, property is flat.Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive.Main soreness of waist and knee joint, muscles and bones flaccidity are weak, limbs are hemiplegia, rheumatic arthralgia, head are wrong dizzy." book on Chinese herbal medicine is new again ": in the fill temperature, control the deficiency of YIN, tonifying YANG road, sharp joint, the water that stimulates the menstrual flow, benefiting blood and regulating blood circulation, antiabortive analgesic therapy.The Semen Coicis slightly sweet flavor, cool in nature.Return spleen, stomach, lung meridian.Function with spleen invigorating eliminating dampness by diuresis, clearing away heat and discharging pus, eliminating impediment, diuretic.The Radix Glycyrrhizae sweet in the mouth, property is flat, and is nontoxic.Return 12 warps.Function cures mainly: treating disorders in five ZANG-organs six internal organs cold and heat pathogen, hard muscles and bones, longue meat, times strength, detoxifcation.Above compatibility of drugs brings out the best in each other.
The present invention follows the prescription principle of the traditional Chinese medical science, the usefulness that is decocted in water for oral dose, and through the clinical application for many years checking, effective percentage is more than 95%, and cure rate has no side effect more than 85%.
The specific embodiment
The invention will be further described below in conjunction with embodiment:
Embodiment 1: a kind of Chinese medicine composition for the treatment of myasthenia gravis is characterized in that its raw material medicines in portions by weight is as follows: the Radix Astragali 8～10g, Ganoderma 6～9g, Radix Angelicae Sinensis 4～6g, the Radix Paeoniae Alba 6～9g, Rhizoma Gastrodiae 6～8g, Flos Carthami 4～6g, Rhizoma Chuanxiong 6～9g, Radix Notoginseng 2～4g, Radix Salviae Miltiorrhizae 6～9g, Rhizoma Cyperi 6～9g, Radix Rehmanniae Preparata 6～10g, Fructus Corni 6～9g, Cortex Acanthopancis 6～9g, Herba Hedyotidis Diffusae 4～6g, Caulis Spatholobi 8～10g, Caulis Piperis Kadsurae 6～10g, Herba Taxilli 6～9g, Radix Panacis Quinquefolii 6～9g, Semen Coicis 8～10g, Radix Glycyrrhizae 6～9g.
Embodiment 2: a kind of Chinese medicine composition for the treatment of myasthenia gravis is characterized in that its raw material medicines in portions by weight is as follows: Radix Astragali 9g, Ganoderma 8g, Radix Angelicae Sinensis 6g, Radix Paeoniae Alba 6g, Rhizoma Gastrodiae 6g, Flos Carthami 4g, Rhizoma Chuanxiong 8, Radix Notoginseng 3g, Radix Salviae Miltiorrhizae 9g, Rhizoma Cyperi 6g, Radix Rehmanniae Preparata 9g, Fructus Corni 6g, Cortex Acanthopancis 8g, Resina Draconis 4g, Caulis Spatholobi 6g, Caulis Piperis Kadsurae 6g, Herba Taxilli 6g, Radix Panacis Quinquefolii 8g, Semen Coicis 8g, Radix Glycyrrhizae 6g.
Clinical efficacy is summed up:
One, physical data: Chinese medicine of the present invention is extensive in clinical practice for many years.Treat 58 routine MG patients, make a definite diagnosis with neostigmine or the edrophonium chloride test positive of going to the hospital in the Jun Jing county.Male 42 examples wherein, the age was 49-62 year, average 53 years old.Woman's 16 examples, the age is in 20-30 year, average 25.5 years old.
Two, diagnostic criteria: the Main Basis of MG clinical diagnosis be have ill fatigability and every day undulatory property myasthenia performance.Show as myasthenia in afternoon or at dusk tired postemphasis, rise morning or have a rest after alleviate, this kind wave phenomenon is referred to as " light dusk in morning is heavy ".Whole body skeletal muscle all can be got involved, and it is the most common to get involved with extraocular muscles, secondly is face and throat muscle and extremity near-end muscle involvement.Neostigmine test or the edrophonium chloride test positive can be made a definite diagnosis.
Three, method of administration: fry in shallow oil 200ml 1 dose, every dose of the every day of being decocted in water for oral dose, being grown up, early, late sub-service.The child takes the circumstances into consideration decrement.
Four, curative effect judging standard
Alleviate fully, disappear without myasthenia symptom sign, take care of oneself, nothing morbidity in 1 year.
Partial rcsponse: clinical symptoms is improved, and slight general weakness can be taken care of oneself;
Invalid: clinical symptoms is unchanged or increase the weight of.
Five, therapeutic effect: the present invention is for many years in clinical practice, and treatment patient 58 examples are alleviated 48 examples, partial rcsponse 8 examples, invalid 2 examples fully.Complete remission rate 82.58%, partial rcsponse rate 13.7%.Quality of life is stablized 49 examples; 7 examples take a turn for the better; Relatively poor 2 examples.
Six, model case
1, open XX, the woman, 29 years old, in December, 2009 was medical.Through regular incidence, two weakness of the lower extremitiess are through injection neostigmine doing well,improving over 2 years in the main suit, and this morbidity increased the weight of 1 day in 2 days.Have a medical check-up: two lower limb weakness.The patient requires to take 20 doses in Chinese medicine of the present invention, and not recurrence is followed up a case by regular visits in the clinical symptoms complete obiteration after 1 year.
2, Lee XX, man, 51 years old, driver.In October, 2010 is medical, and the main suit fatigue and mild cold symptoms occur because of long-distance running, and two weakness of the lower extremitiess increased the weight of again behind the doing well,improving through injecting neostigmine 1 time in 2 days after 3 days.Have a medical check-up: two lower limb weakness.The patient requires to take 20 doses in Chinese medicine of the present invention, and the clinical symptoms complete obiteration was followed up a case by regular visits to after 1 year.
3, Wu X, man, 56 years old.In April, 2011 is medical.The main suit fatigue and mild cold symptoms occur because of long-distance running.Two weakness of the lower extremitiess increased the weight of again behind the doing well,improving through injecting neostigmine 1 time in 2 days after 3 days.Have a medical check-up: two lower limb weakness.The patient requires to take 20 doses in Chinese medicine of the present invention, and not recurrence is followed up a case by regular visits in the clinical symptoms complete obiteration after 1 year.
Claims (1)
1. a Chinese medicine composition for the treatment of myasthenia gravis is characterized in that its raw material medicines in portions by weight is as follows: the Radix Astragali 8～10g, Ganoderma 6～9g, Radix Angelicae Sinensis 4～6g, the Radix Paeoniae Alba 6～9g, Rhizoma Gastrodiae 6～8g, Flos Carthami 4～6g, Rhizoma Chuanxiong 6～9g, Radix Notoginseng 2～4g, Radix Salviae Miltiorrhizae 6～9g, Rhizoma Cyperi 6～9g, Radix Rehmanniae Preparata 6～10g, Cortex Acanthopancis 6～9g, Herba Hedyotidis Diffusae 4～6g, Caulis Spatholobi 8～10g, Caulis Piperis Kadsurae 6～10g, Herba Taxilli 6～9g, Radix Panacis Quinquefolii 6～9g, Semen Coicis 8～10g, Radix Glycyrrhizae 6～9g.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189525A (en) * | 2014-09-11 | 2014-12-10 | 济南环太机电技术有限公司 | Traditional Chinese medicine decoction for treating myasthenia gravis |
| CN104474353A (en) * | 2014-12-19 | 2015-04-01 | 李爱花 | Medicine for treating myasthenia gravis and preparation method of medicine |
| CN105688033A (en) * | 2016-01-29 | 2016-06-22 | 李志芳 | Traditional Chinese medicine composition for treating myasthenia gravis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1557375A (en) * | 2004-01-29 | 2004-12-29 | 河北省民生医药研究所 | Medicinal composition for treating amyotrophy |
| CN1679905A (en) * | 2005-01-12 | 2005-10-12 | 王振球 | Chinese medicine for treating myasthenia gravis |
-
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- 2013-01-10 CN CN2013100212265A patent/CN103041228A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1557375A (en) * | 2004-01-29 | 2004-12-29 | 河北省民生医药研究所 | Medicinal composition for treating amyotrophy |
| CN1679905A (en) * | 2005-01-12 | 2005-10-12 | 王振球 | Chinese medicine for treating myasthenia gravis |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189525A (en) * | 2014-09-11 | 2014-12-10 | 济南环太机电技术有限公司 | Traditional Chinese medicine decoction for treating myasthenia gravis |
| CN104474353A (en) * | 2014-12-19 | 2015-04-01 | 李爱花 | Medicine for treating myasthenia gravis and preparation method of medicine |
| CN105688033A (en) * | 2016-01-29 | 2016-06-22 | 李志芳 | Traditional Chinese medicine composition for treating myasthenia gravis |
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Application publication date: 20130417 |