CN104189525A - Traditional Chinese medicine decoction for treating myasthenia gravis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine decoction for treating myasthenia gravis and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine decoction is prepared from the following raw materials in parts by weight: 25 to 30 parts of astragalus membranaceus, 25 to 30 parts of salvia miltiorrhiza, 12 to 16 parts of rhizoma atractylodis macrocephalae, 20 to 25 parts of poria cocos, 15 to 20 parts of rhizoma gastrodiae, 12 to 16 parts of radix bupleuri, 8 to 15 parts of buthus martensi karsch, 10 to 16 parts of safflower carthamus, 10 to 16 parts of pillis ophidiae, 3 to 7 parts of centipede, 12 to 18 parts of herba epimedii, 18 to 25 parts of angelica sinensis, 12 to 18 parts of garter snake, 12 to 16 parts of fructus foeniculi, 5 to 9 parts of aconitum carmichaelii, 20 to 25 parts of rhizoma polygonati, 10 to 16 parts of cassia twig, 12 to 18 parts of radix clematidis, 20 to 30 parts of prepared radix rehmanniae, 20 to 25 parts of caulis spatholobi and 8 to 12 parts of licorice root. The traditional Chinese medicine decoction has the beneficial effects of invigorating spleen and kidneys, promoting blood circulation to remove blood stasis and removing wind evil to dredge collaterals, and has a good treatment effect on myasthenia gravis.

Description

A kind of Chinese medicine decoction for the treatment of myasthenia gravis

Technical field

The present invention relates to a kind of medicine for the treatment of myasthenia gravis, belong to technical field of Chinese medicines, specifically a kind of Chinese medicine decoction for the treatment of myasthenia gravis.

Background technology

Myasthenia gravis is a kind of chronic disease, is very easy to fatigue, and produces temporary paralysis because conduction block between nerve and muscle causes some striped muscle, after having a rest, improves; Can cause paralysis late period, minority patient's cardiac muscle also can be got involved.Primary disease belongs to Chinese medicine myopathy scope.

The traditional Chinese medical science is thought, causes the cause of disease of myopathy, has two kinds of diseases caused by exogenous pathogenic factor and internal injuries.As evil in warm poison pathogenic with occupying wetland for a long time, belong to diseases caused by exogenous pathogenic factor; Weakness of the spleen and stomach and caused by liver and kidney deficiency is internal injury.But diseases caused by exogenous pathogenic factor are caused a disease, with the passing of time endlessly also must visceral function, so both mutuals contacts.Meanwhile, though when just sick due to diseases caused by exogenous pathogenic factor factor, but positive QI-insufficiency or main endogenous cause of ill.To the treatment of primary disease, doctor trained in Western medicine is used anticholinesterase drug etc., and so the state of an illness easily fluctuates, and side effect is large. and curative effect is undesirable.The traditional Chinese medical science is thought the Etiological pathogenesis of primary disease, is weakness of the spleen and kidney.The kidney being the origin of congenital constitution, the root of main the whole body yang-energy, store essential substances, main bone; The spleen being the foundation of acquired constitution. the muscle of main the whole body.Prolonged illness, fatigue or plain body void, make the gas of spleen kidney impaired, and the mistake of muscle muscles and bones is supported, and occurs primary disease.In addition, the empty weakened defensive QI of body, ailment said due to cold or exposure is taken advantage of void and people, wind stasis blocking network, venation arthralgia due to blood stasis, need not a little less than limbs flaccidity.Therefore treatment is upper taking strengthening spleen, tonifying kidney, blood circulation promoting and blood stasis dispelling as main, and assistant is with expel wind to dredge collateral.The present invention is to provide a kind of Chinese medicine decoction for the treatment of myasthenia gravis, and using the traditional Chinese herbal medicine of China is raw material, is configured and is formed by clinic tests and repeated verification, meets the theory of Chinese medicine, has good therapeutic effect.

Summary of the invention

The present invention is to provide a kind of Chinese medicine decoction for the treatment of myasthenia gravis, and using the traditional Chinese herbal medicine of China is raw material, is configured and is formed by clinic tests and repeated verification, meets the theory of Chinese medicine, has good therapeutic effect.

The property of medicine of the selected Chinese herbal medicine of the present invention and function cure mainly and are respectively:

The Radix Astragali [nature and flavor] is sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.

Radix Salviae Miltiorrhizae: [nature and flavor] hardship, is slightly cold.[return through] GUIXIN, Liver Channel.[function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.

The Rhizoma Atractylodis Macrocephalae: [nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, frequent fetal movement.

Poria: [nature and flavor] are sweet, light is flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.

Rhizoma Gastrodiae [nature and flavor] is sweet, flat.[return through] returns Liver Channel.[function cures mainly] suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Be used for having a headache dizzy, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.

Radix Bupleuri [nature and flavor] hardship, is slightly cold.[return through] returns liver, gallbladder meridian.[function cures mainly] reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.

Gekko Swinhonis [nature and flavor] " detailed outline ": " salty, cold, slightly poisonous." [function cures mainly] dispels the wind, arresting convulsion, eliminating stagnation, removing toxic substances.Control paralysis due to windstroke, severe and migratory arthralgia pain, wind-phlegm infantile convulsion, scrofula, malignant boil.1. " detailed outline ": " control paralysis due to windstroke, brothers' erectile problem, or severe and migratory arthralgia pain, and puerperal tetanus infantile convulsion, infantile emaciation, accumulation of blood becomes painful abdominal mass, strict wind scrofula; Treat scorpion sting."

2. " Traditional Chinese Medicine in Sichuan will ": " wind dispelling, removing blood stasis amasss enclosed mass, controls and swells and ache."

Scorpio nature and flavor: pungent, flat; Poisonous.Return Liver Channel.Effect endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Main syndrome is used for infantile convulsion, tic spasm, and middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.

Flos Carthami [nature and flavor] is pungent, temperature.[return through] GUIXIN, Liver Channel.[function cures mainly] promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.

Periostracum Serpentis [nature and flavor] is salty, sweet, flat.[return through] returns Liver Channel.[function cures mainly] dispels the wind, arresting convulsion, removing toxic substances, nebula removing.For infantile convulsion, tic spasm, cataracta, sore throat, furuncle is swollen, skin pruritus.

Scolopendra [nature and flavor] is pungent, temperature; Poisonous.[return through] returns Liver Channel.[function cures mainly] endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.

Herba Epimedii [nature and flavor] acrid, sweet, warm.[return through] returns liver, kidney channel.[function cures mainly] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.

Radix Angelicae Sinensis: [nature and flavor] are warm in nature, sweet in the mouth, pungent.[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.

Zaocys [nature and flavor] is sweet salty, flat.[function cures mainly] wind-damp dispelling, the meridian dredging.Dispelling the wind and dampness pathogens insensitive impediment, numbness of the skin, bone, tuberculosis of joint, rubella scabies, leprosy, tetanus, poliomyelitis.1. " property of medicine opinion ": " control pyretic toxicity wind, the raw skin ulcer of skin, eyebrow must come off, the Guo scabies etc. of itching." 2. " Kaibao Bencao)): " main all wind scabies urticarias, scabies, munbness, all wind of insensitive impediment." 3. " detailed outline ": " merit and Agkistrodon with and property is kind nontoxic." 4. " medical center bun is wanted ": " YIN nourishing improving eyesight."

Fructus Foeniculi [nature and flavor] is pungent, temperature.[return through] returns liver,kidney,spleen, stomach warp.[function cures mainly] dispersing cold for relieving pain, regulating qi-flowing for harmonizing stomach.For colic of cold type stomachache, the testis swelling and hanging down of either of the testes, dysmenorrhea, few abdomen cold type of pain, abdominal distention, lack of appetite and vomiting, hydrocele of testis.Salt Fructus Foeniculi warming the kidney dispersing cold for relieving pain.For colic of cold type stomachache, the testis swelling and hanging down of either of the testes, through cold stomachache.

Radix Aconiti Lateralis Preparata: [nature and flavor] are pungent, sweet is warm greatly; Poisonous.[return through] GUIXIN, kidney, spleen channel.[function cures mainly] recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.

Rhizoma Polygonati [nature and flavor] is sweet, flat.[return through] returns spleen, lung, kidney channel.[function cures mainly] boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.

Ramulus Cinnamomi: [nature and flavor] acrid, sweet, warm.[return through] GUIXIN, lung, urinary bladder channel.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.

Radix Clematidis [nature and flavor] is pungent, salty, temperature.[return through] returns urinary bladder channel.[function cures mainly] expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.For rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, the bone larynx of choking with sobs.

Radix Rehmanniae Preparata [nature and flavor] is sweet, tepor.[return through] returns liver, kidney channel.[function cures mainly] nourishing YIN and supplementing blood, beneficial essence is filled out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair.

Caulis Spatholobi meridian distribution of property and flavor: bitter, sweet, temperature.Return liver, kidney channel.Function cures mainly: enrich blood, invigorate blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.

Radix Glycyrrhizae: [nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

The invention provides a kind of Chinese medicine decoction for the treatment of myasthenia gravis, made by the crude drug of following weight proportion:

Radix Astragali 25-30 part, Radix Salviae Miltiorrhizae 25-30 part, Rhizoma Atractylodis Macrocephalae 12-16 part, Poria 20-25 part, Rhizoma Gastrodiae 15-20 part, Radix Bupleuri 12-16 part, Scorpio 8-15 part, Flos Carthami 10-16 part, Periostracum Serpentis 10-16 part, Scolopendra 3-7 part, Herba Epimedii 12-18 part, Radix Angelicae Sinensis 18-25 part, Zaocys 12-18 part, Fructus Foeniculi 12-16 part, Radix Aconiti Lateralis Preparata 5-9 part, Rhizoma Polygonati 20-25 part, Ramulus Cinnamomi 10-16 part, Radix Clematidis 12-18 part, Radix Rehmanniae Preparata 20-30 part, Caulis Spatholobi 20-25 part, Radix Glycyrrhizae 8-12 part;

Described a kind of Chinese medicine decoction preparation method for the treatment of myasthenia gravis, concrete steps are:

1. before decocting, prepare, choose marmite and clean water, take in proportion medical material, cooked Mel and a little boiled water for Radix Glycyrrhizae, slightly vexed after mixing thoroughly, fry to yellow to buff, when tack-free, take out, dry in the air cool for subsequent use, Radix Aconiti Lateralis Preparata is tamping with gauze, Scorpio, Scolopendra are separately closed with all the other medical materials and soak 2-3 hour with gauze;

2. decoct, soaked medical material is put into marmite, the Radix Aconiti Lateralis Preparata 1 hour of being decocted first, controls and decocts the water yield to whole medical materials surfaces 5 centimetres, exceedes 2 centimetres of medicinal residues while again decoction; Before not boiling, with high heat, after boiling, use again slow fire instead, keep micro-and boil; Decoct three times, decoct for the first time 30-35 minute, decoct for the second time 20-25 minute, decoct for the third time 15-20 minute, the medicinal liquid merging after decocting is 400-500ml;

3. preserve: be preferably kept in the cold closet of refrigerator or shady and cool ventilation place, be no more than 2 days.

Described a kind of Chinese medicine decoction for the treatment of myasthenia gravis, made by the crude drug of following weight proportion:

Radix Astragali 26-29 part, Radix Salviae Miltiorrhizae 26-29 part, Rhizoma Atractylodis Macrocephalae 13-15 part, Poria 21-24 part, Rhizoma Gastrodiae 16-19 part, Radix Bupleuri 13-15 part, Scorpio 9-14 part, Flos Carthami 11-15 part, Periostracum Serpentis 11-15 part, Scolopendra 4-6 part, Herba Epimedii 13-17 part, Radix Angelicae Sinensis 19-24 part, Zaocys 13-17 part, Fructus Foeniculi 13-15 part, Radix Aconiti Lateralis Preparata 6-8 part, Rhizoma Polygonati 21-24 part, Ramulus Cinnamomi 11-15 part, Radix Clematidis 13-17 part, Radix Rehmanniae Preparata 21-29 part, Caulis Spatholobi 21-24 part, Radix Glycyrrhizae 9-11 part.

Described a kind of Chinese medicine decoction for the treatment of myasthenia gravis, made by the crude drug of following weight proportion:

27 parts of the Radixs Astragali, 28 parts of Radix Salviae Miltiorrhizaes, 14 parts of the Rhizoma Atractylodis Macrocephalaes, 23 parts, Poria, 17 parts, Rhizoma Gastrodiae, 14 parts of Radix Bupleuri, 11 parts of Scorpios, 12 parts, Flos Carthami, 12 parts of Periostracum Serpentiss, 4 parts of Scolopendras, 15 parts of Herba Epimedii, 22 parts of Radix Angelicae Sinensis, 14 parts of Zaocys, 14 parts of Fructus Foeniculi, 7 parts of Radix Aconiti Lateralis Preparatas, 23 parts of Rhizoma Polygonatis, 13 parts of Ramulus Cinnamomi, 14 parts of Radix Clematidis, 25 parts of Radix Rehmanniae Preparata, 23 parts of Caulis Spatholobis, 10 parts, Radix Glycyrrhizae.

Usefulness of the present invention: the invention provides a kind of Chinese medicine decoction for the treatment of myasthenia gravis, outside the training spleen reinforcing kidneys such as the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria, Herba Epimedii, with Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis, Flos Carthami blood circulation promoting and blood stasis dispelling; With Radix Bupleuri, the Fructus Foeniculi yang invigorating of regulating the flow of vital energy, and be equipped with the animal kind medicines such as Scolopendra, Gekko Swinhonis, Scorpio, Zaocys, get its walking and attack the characteristic of altering, to dredge through reaching network, reach treating blood disorders stagnant, the relieving the inhibited functional activities of QI that disappears; The Radix Aconiti Lateralis Preparata kidney invigorating and YANG supporting blood vessels that pass through, Radix Rehmanniae Preparata, Rhizoma Polygonati, Ramulus Cinnamomi, Radix Clematidis, Caulis Spatholobi active the promoting blood circulation of enriching blood, Radix Glycyrrhizae Preparata tonify deficiency and medicine, the dry property of pharmacy, the kind reason of Rhizoma Gastrodiae wind syndrome caused by deficiency, coordinate Periostracum Serpentis and blood circulation promoting medicine energy promoting blood circulation by removing wind, the systolic and diastolic function that strengthens blood vessel, all medicines share, to reach strengthening spleen, tonifying kidney, blood circulation promoting and blood stasis dispelling as main, and assistant is with the object of expel wind to dredge collateral, and treatment myasthenia gravis is had to good curative effect.

Detailed description of the invention

Embodiment 1

Treat a Chinese medicine decoction for myasthenia gravis, made by the crude drug of following weight proportion:

25 parts of the Radixs Astragali, 25 parts of Radix Salviae Miltiorrhizaes, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts, Poria, 15 parts, Rhizoma Gastrodiae, 12 parts of Radix Bupleuri, 8 parts of Scorpios, 10 parts, Flos Carthami, 10 parts of Periostracum Serpentiss, 3 parts of Scolopendras, 12 parts of Herba Epimedii, 18 parts of Radix Angelicae Sinensis, 12 parts of Zaocys, 12 parts of Fructus Foeniculi, 5 parts of Radix Aconiti Lateralis Preparatas, 20 parts of Rhizoma Polygonatis, 10 parts of Ramulus Cinnamomi, 12 parts of Radix Clematidis, 20 parts of Radix Rehmanniae Preparata, 20 parts of Caulis Spatholobis, 8 parts, Radix Glycyrrhizae;

Preparation method, concrete steps are:

1. before decocting, prepare, choose marmite and clean water, take in proportion medical material, cooked Mel and a little boiled water for Radix Glycyrrhizae, slightly vexed after mixing thoroughly, fry to yellow to buff, when tack-free, take out, dry in the air cool for subsequent use, Radix Aconiti Lateralis Preparata is tamping with gauze, Scorpio, Scolopendra are separately closed with all the other medical materials and soak 2-3 hour with gauze;

2. decoct, soaked medical material is put into marmite, the Radix Aconiti Lateralis Preparata 1 hour of being decocted first, controls and decocts the water yield to whole medical materials surfaces 5 centimetres, exceedes 2 centimetres of medicinal residues while again decoction; Before not boiling, with high heat, after boiling, use again slow fire instead, keep micro-and boil; Decoct three times, decoct for the first time 35 minutes, decoct for the second time 25 minutes, decoct for the third time 20 minutes, the medicinal liquid merging after decocting is 400-500ml;

3. preserve: be preferably kept in the cold closet of refrigerator or shady and cool ventilation place, be no more than 2 days.

Embodiment 2

Treat a Chinese medicine decoction for myasthenia gravis, made by the crude drug of following weight proportion:

26 parts of the Radixs Astragali, 26 parts of Radix Salviae Miltiorrhizaes, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 21 parts, Poria, 16 parts, Rhizoma Gastrodiae, 13 parts of Radix Bupleuri, 9 parts of Scorpios, 11 parts, Flos Carthami, 11 parts of Periostracum Serpentiss, 4 parts of Scolopendras, 13 parts of Herba Epimedii, 19 parts of Radix Angelicae Sinensis, 13 parts of Zaocys, 13 parts of Fructus Foeniculi, 6 parts of Radix Aconiti Lateralis Preparatas, 21 parts of Rhizoma Polygonatis, 11 parts of Ramulus Cinnamomi, 13 parts of Radix Clematidis, 21 parts of Radix Rehmanniae Preparata, 21 parts of Caulis Spatholobis, 9 parts, Radix Glycyrrhizae.

Preparation method is with embodiment 1

Embodiment 3

Treat a Chinese medicine decoction for myasthenia gravis, made by the crude drug of following weight proportion:

27 parts of the Radixs Astragali, 28 parts of Radix Salviae Miltiorrhizaes, 14 parts of the Rhizoma Atractylodis Macrocephalaes, 23 parts, Poria, 17 parts, Rhizoma Gastrodiae, 14 parts of Radix Bupleuri, 11 parts of Scorpios, 12 parts, Flos Carthami, 12 parts of Periostracum Serpentiss, 4 parts of Scolopendras, 15 parts of Herba Epimedii, 22 parts of Radix Angelicae Sinensis, 14 parts of Zaocys, 14 parts of Fructus Foeniculi, 7 parts of Radix Aconiti Lateralis Preparatas, 23 parts of Rhizoma Polygonatis, 13 parts of Ramulus Cinnamomi, 14 parts of Radix Clematidis, 25 parts of Radix Rehmanniae Preparata, 23 parts of Caulis Spatholobis, 10 parts, Radix Glycyrrhizae.

Preparation method is with embodiment 1

Embodiment 4

Treat a Chinese medicine decoction for myasthenia gravis, made by the crude drug of following weight proportion:

29 parts of the Radixs Astragali, 29 parts of Radix Salviae Miltiorrhizaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 24 parts, Poria, 19 parts, Rhizoma Gastrodiae, 15 parts of Radix Bupleuri, 14 parts of Scorpios, 15 parts, Flos Carthami, 15 parts of Periostracum Serpentiss, 6 parts of Scolopendras, 17 parts of Herba Epimedii, 24 parts of Radix Angelicae Sinensis, 17 parts of Zaocys, 15 parts of Fructus Foeniculi, 8 parts of Radix Aconiti Lateralis Preparatas, 24 parts of Rhizoma Polygonatis, 15 parts of Ramulus Cinnamomi, 17 parts of Radix Clematidis, 29 parts of Radix Rehmanniae Preparata, 24 parts of Caulis Spatholobis, 11 parts, Radix Glycyrrhizae.

Preparation method is with embodiment 1

Embodiment 5

Treat a Chinese medicine decoction for myasthenia gravis, made by the crude drug of following weight proportion:

30 parts of the Radixs Astragali, 30 parts of Radix Salviae Miltiorrhizaes, 16 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts, Poria, 20 parts, Rhizoma Gastrodiae, 16 parts of Radix Bupleuri, 15 parts of Scorpios, 16 parts, Flos Carthami, 16 parts of Periostracum Serpentiss, 7 parts of Scolopendras, 18 parts of Herba Epimedii, 25 parts of Radix Angelicae Sinensis, 18 parts of Zaocys, 16 parts of Fructus Foeniculi, 9 parts of Radix Aconiti Lateralis Preparatas, 25 parts of Rhizoma Polygonatis, 16 parts of Ramulus Cinnamomi, 18 parts of Radix Clematidis, 30 parts of Radix Rehmanniae Preparata, 25 parts of Caulis Spatholobis, 12 parts, Radix Glycyrrhizae.

Preparation method is with embodiment 1

The using method of Chinese medicine decoction of the present invention: every day potion, point take for three times.Avoid eating anything raw or cold.

Compliance test result:

Choose 400 people that accept voluntarily controlled trial from the patient of institute of traditional Chinese medicine's outpatient service or general hospital outpatient service myasthenia gravis, record sex, the Back ground Informations such as age.According to age cohorts, every group of number random-blind selects half to take Western medicine azathioprine, and second half takes the present invention's Chinese medicine of filling a prescription, and be 3 months medicine time, and curing result can be referring to table 1.

Table 1

?

10-20 year

20-30 year

30-40 year

40-50 year

50-60 year

More than 60 years old

Number

26 people

54 people

110 people

100 people

70 people

40 people

Western medicine recovery from illness

1 people

1 people

4 people

5 people

1 people

0 people

Chinese medicine recovery from illness of the present invention

11 people

25 people

52 people

46 people

32 people

18 people

Western medicine cure rate

7.7%

3.7%

7.3%

10%

2.9%

0%

Chinese medicine cure rate of the present invention

84.6%

92.6%

94.5%

92.0%

91.4%

90.0%

Interpretation of result: random-blind choosing grouping, each ages two group membership does not exist biased and significant difference.

The comparison of cure rate:

Wherein take Western medicine cure rate and be the recovery from illness number of taking Western medicine by this group and take the percentage ratio of the total number of persons of Western medicine divided by this group, taking Chinese medicine cure rate of the present invention is the percentage ratio of being taken Chinese medicine total number of persons by the recovery from illness number of taking Chinese medicine divided by this group.

10-20 year age group, taking Western medicine cure rate is 7.7%, taking Chinese medicine cure rate of the present invention is 84.6%, through X ²inspection, difference analysis (P<0.01), can find out, 10-20 year patient's patient's cure rate of taking Chinese medicine of the present invention of age group have significant difference compared with taking Western medicine cure rate.

20-30 year age group, taking Western medicine cure rate is 3.7%, taking Chinese medicine cure rate of the present invention is 92.6%, through X ²inspection, difference analysis (P<0.01), can find out, 20-30 year patient's patient's cure rate of taking Chinese medicine of the present invention of age group have significant difference compared with taking Western medicine cure rate.

30-40 year age group, taking Western medicine cure rate is 7.3%, taking Chinese medicine cure rate of the present invention is 94.5%, through X ²inspection, difference analysis (P<0.01), can find out, 30-40 year patient's patient's cure rate of taking Chinese medicine of the present invention of age group have significant difference compared with taking Western medicine cure rate.

40-50 year age group, taking Western medicine cure rate is 10%, taking Chinese medicine cure rate of the present invention is 92.0%, through X ²inspection, difference analysis (P<0.01), can find out, 40-50 year patient's patient's cure rate of taking Chinese medicine of the present invention of age group have significant difference compared with taking Western medicine cure rate.

50-60 year age group, taking Western medicine cure rate is 2.9%, taking Chinese medicine cure rate of the present invention is 91.4%, through X ²inspection, difference analysis (P<0.01), can find out, 50-60 year patient's patient's cure rate of taking Chinese medicine of the present invention of age group have significant difference compared with taking Western medicine cure rate.

More than 60 years old age group, taking Western medicine cure rate is 0%, taking Chinese medicine cure rate of the present invention is 90.0%.Through X ²inspection, difference analysis (P<0.01), can find out, patient's cure rate that the patient of more than 60 years old age group takes Chinese medicine of the present invention has significant difference compared with taking Western medicine cure rate.

The effect that treatment by Chinese herbs dampness-heat of the liver of the present invention is described is more remarkable than western medicine effect, and all reaches more than 84.6% at the therapeutic effect of each age group, and the treatment of all age group is not had to diversity difference, has good curative effect.

Model case

Case 1: Zhang, man, 13 years old; Cardinal symptom: spiritlessness and weakness, dizzy, blepharoptosis, uncomfortable in chest, nauseating, throat if any thing block, dysphagia, be myasthenia gravis through hospital diagnosis; Take Chinese medicine decoction embodiment 1 of the present invention and fill a prescription 2 months, symptom is obviously improved, and within the 3rd month, continues to take, and basic recovery normally, without other reactions.

Case 2: Lee, man, 27 years old, cardinal symptom: health is become thin, low voice timidness due to deficiency of QI, blepharoptosis, eyeball can not rotate, myasthenia of limbs, can not walk, pale complexion, lethargy, is myasthenia gravis through hospital diagnosis; Take Chinese medicine decoction embodiment 2 of the present invention and fill a prescription 1.5 months, symptom is obviously improved, and continues to take, and basic recovery normally, without other reactions.

Case 3: king so-and-so, female, 35 years old, cardinal symptom: endophthalmos zygomatic process, xerosis cutis, squamous and dry skin, stomach poor appetite, half congealed when stool, light red tongue limit has petechia, tongue white, stringy and thready pulse, is myasthenia gravis through hospital diagnosis; Take Chinese medicine decoction embodiment 3 of the present invention and fill a prescription 2 months, symptom is obviously improved, and within the 3rd month, continues to take, and basic recovery normally, without other reactions.

Case 4: hole so-and-so, female, 48 years old, cardinal symptom: shallow complexion, become thin, spiritlessness and weakness, Dual-eyelid is sagging, extremity flaccidity is weak unable, stomach poor appetite, xerostomia. squamous and dry skin, light red tongue limit purple, tongue are white, a little less than deep-thready pulse, are myasthenia gravis through hospital diagnosis; Take Chinese medicine decoction embodiment 4 of the present invention and fill a prescription 2 months, symptom is obviously improved, and within the 3rd month, continues to take, and basic recovery normally, without other reactions.

Case 5: high certain, man, 56 years old, cardinal symptom: occur dizzy, ear toot, spiritlessness and weakness, dizzy, blepharoptosis, uncomfortable in chest, nauseating, be myasthenia gravis through hospital diagnosis; Take Chinese medicine decoction embodiment 5 of the present invention and fill a prescription 1 month, symptom is obviously improved, and within the 2nd month, continues to take, and basic recovery normally, without other reactions.

Case 6: Liu so-and-so, female, 65 years old, cardinal symptom: health is become thin, low voice timidness due to deficiency of QI, blepharoptosis, eyeball can not rotate, myasthenia of limbs, can not walk, be myasthenia gravis through hospital diagnosis; Take Chinese medicine decoction embodiment 3 of the present invention and fill a prescription 2 months, symptom is obviously improved, and within the 3rd month, continues to take, and basic recovery normally, without other reactions.

Claims (3)

1. treat a Chinese medicine decoction for myasthenia gravis, it is characterized in that being made by the crude drug of following weight proportion:

Radix Astragali 25-30 part, Radix Salviae Miltiorrhizae 25-30 part, Rhizoma Atractylodis Macrocephalae 12-16 part, Poria 20-25 part, Rhizoma Gastrodiae 15-20 part, Radix Bupleuri 12-16 part, Scorpio 8-15 part, Flos Carthami 10-16 part, Periostracum Serpentis 10-16 part, Scolopendra 3-7 part, Herba Epimedii 12-18 part, Radix Angelicae Sinensis 18-25 part, Zaocys 12-18 part, Fructus Foeniculi 12-16 part, Radix Aconiti Lateralis Preparata 5-9 part, Rhizoma Polygonati 20-25 part, Ramulus Cinnamomi 10-16 part, Radix Clematidis 12-18 part, Radix Rehmanniae Preparata 20-30 part, Caulis Spatholobi 20-25 part, Radix Glycyrrhizae 8-12 part;

Described a kind of Chinese medicine decoction preparation method for the treatment of myasthenia gravis, concrete steps are:

1. before decocting, prepare, choose marmite and clean water, take in proportion medical material, cooked Mel and a little boiled water for Radix Glycyrrhizae, slightly vexed after mixing thoroughly, fry to yellow to buff, when tack-free, take out, dry in the air cool for subsequent use, Radix Aconiti Lateralis Preparata is tamping with gauze, Scorpio, Scolopendra are separately closed with all the other medical materials and soak 2-3 hour with gauze;

2. decoct, soaked medical material is put into marmite, the Radix Aconiti Lateralis Preparata 1 hour of being decocted first, controls and decocts the water yield to whole medical materials surfaces 5 centimetres, exceedes 2 centimetres of medicinal residues while again decoction; Before not boiling, with high heat, after boiling, use again slow fire instead, keep micro-and boil; Decoct three times, decoct for the first time 30-35 minute, decoct for the second time 20-25 minute, decoct for the third time 15-20 minute, the medicinal liquid merging after decocting is 400-500ml;

3. preserve: be preferably kept in the cold closet of refrigerator or shady and cool ventilation place, be no more than 2 days.

2. a kind of Chinese medicine decoction for the treatment of myasthenia gravis according to claim 1, is characterized in that being made up of the crude drug of following weight proportion:

Radix Astragali 26-29 part, Radix Salviae Miltiorrhizae 26-29 part, Rhizoma Atractylodis Macrocephalae 13-15 part, Poria 21-24 part, Rhizoma Gastrodiae 16-19 part, Radix Bupleuri 13-15 part, Scorpio 9-14 part, Flos Carthami 11-15 part, Periostracum Serpentis 11-15 part, Scolopendra 4-6 part, Herba Epimedii 13-17 part, Radix Angelicae Sinensis 19-24 part, Zaocys 13-17 part, Fructus Foeniculi 13-15 part, Radix Aconiti Lateralis Preparata 6-8 part, Rhizoma Polygonati 21-24 part, Ramulus Cinnamomi 11-15 part, Radix Clematidis 13-17 part, Radix Rehmanniae Preparata 21-29 part, Caulis Spatholobi 21-24 part, Radix Glycyrrhizae 9-11 part.

3. a kind of Chinese medicine decoction for the treatment of myasthenia gravis according to claim 1, is characterized in that being made up of the crude drug of following weight proportion:

27 parts of the Radixs Astragali, 28 parts of Radix Salviae Miltiorrhizaes, 14 parts of the Rhizoma Atractylodis Macrocephalaes, 23 parts, Poria, 17 parts, Rhizoma Gastrodiae, 14 parts of Radix Bupleuri, 11 parts of Scorpios, 12 parts, Flos Carthami, 12 parts of Periostracum Serpentiss, 4 parts of Scolopendras, 15 parts of Herba Epimedii, 22 parts of Radix Angelicae Sinensis, 14 parts of Zaocys, 14 parts of Fructus Foeniculi, 7 parts of Radix Aconiti Lateralis Preparatas, 23 parts of Rhizoma Polygonatis, 13 parts of Ramulus Cinnamomi, 14 parts of Radix Clematidis, 25 parts of Radix Rehmanniae Preparata, 23 parts of Caulis Spatholobis, 10 parts, Radix Glycyrrhizae.