CN103341153B - Traditional Chinese medicine composition for treating raynaud disease - Google Patents

Traditional Chinese medicine composition for treating raynaud disease Download PDF

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Publication number
CN103341153B
CN103341153B CN201310333652.2A CN201310333652A CN103341153B CN 103341153 B CN103341153 B CN 103341153B CN 201310333652 A CN201310333652 A CN 201310333652A CN 103341153 B CN103341153 B CN 103341153B
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parts
radix
chinese medicine
medicine composition
raynaud disease
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CN201310333652.2A
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CN103341153A (en
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刘建飞
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Sun Yujie
Yang Wenwen
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Abstract

The invention relates to a traditional Chinese medicine composition for treating raynaud disease. The traditional Chinese medicine composition is characterized by being prepared from the following raw medicinal materials in parts by weight: 15-25 parts of red flower, 15-25 parts of ligusticum wallichii, 15-25 parts of fructus aurantii, 15-25 parts of mulberry twig, 15-25 parts of rhizoma curculiginis, 12-18 parts of prepared rehmannia root, 12-18 parts of monkshood, 12-18 parts of radix aconiti agrestis, 12-18 parts of angelica sinensis, 12-18 parts of red peony root, 12-18 parts of radix codonopsis, 12-18 parts of astragalus membranaceus, 12-18 parts of salviae miltiorrhizae, 12-18 parts of caulis spatholobi, 12-18 parts of liquidambar formosana hance, 12-18 parts of manis pentadactyla, 12-18 parts of radix clematidis, 6-12 parts of cinnamon, 6-12 parts of asarum, 6-12 parts of divaricate saposhnikovia root, 6-12 parts of rhizoma zingiberis, 6-12 parts of cassia twig and 3-9 parts of semen brassicae. The traditional Chinese medicine composition provided by the invention has the advantages of good curative effect, quick effect exertion, no toxic and side effects, low treatment cost, and simple preparation method.

Description

A kind of Chinese medicine composition for the treatment of raynaud disease
Technical field
The present invention relates to technical field of traditional Chinese medicine pharmacy, particularly relate to a kind of Chinese medicine composition for the treatment of raynaud disease.
Background technology
Raynaud disease be a kind of meet cold or nervous after, cause acro-ischemia to change into the disease of feature, also known as acra vasospastic disease with paroxysmal acra small artery strong contraction.During outbreak, acra skin becomes livid purple from pale, then transfers flushing to.Raynaud disease female patient is common, and M-F is 1:10, and age of onset is many at 20 ~ 30 years old.The cause of disease of raynaud disease is still not exclusively clear and definite at present, relevant to heredity and environmental factors.Cold stimulation, excited or psychentonia are main motivating factors.Other inducements have infection, fatigue etc.
At present, based on blood vessel dilating, there is the deficiencies such as curative effect is not good enough, side effect is large in the medicine for the treatment of raynaud disease.
Summary of the invention
The technical problem to be solved in the present invention is: be solve the deficiencies in the prior art, the invention provides a kind of Chinese medicine composition for the treatment of raynaud disease, the present invention has good effect, instant effect, has no side effect, treatment cost is low, the simple advantage of preparation method.
A kind of Chinese medicine composition for the treatment of raynaud disease, be made up of the crude drug of following weight portion: Flos Carthami 15-25 part, Rhizoma Chuanxiong 15-25 part, Fructus Aurantii 15-25 part, Ramulus Mori 15-25 part, Rhizoma Curculiginis 15-25 part, Radix Rehmanniae Preparata 12-18 part, Radix Aconiti 12-18 part, Radix Aconiti Kusnezoffii 12-18 part, Radix Angelicae Sinensis 12-18 part, Radix Paeoniae Rubra 12-18 part, Radix Codonopsis 12-18 part, Radix Astragali 12-18 part, Radix Salviae Miltiorrhizae 12-18 part, Caulis Spatholobi 12-18 part, Fructus Liquidambaris 12-18 part, Squama Manis 12-18 part, Radix Clematidis 12-18 part, Cortex Cinnamomi 6-12 part, Herba Asari 6-12 part, Radix Saposhnikoviae 6-12 part, Rhizoma Zingiberis 6-12 part, Ramulus Cinnamomi 6-12 part, Semen Sinapis Albae 3-9 part.
The Chinese medicine composition of described treatment raynaud disease, it is preferably: be made up of the crude drug of following weight portion: 20 parts, Flos Carthami, Rhizoma Chuanxiong 20 parts, Fructus Aurantii 20 parts, Ramulus Mori 20 parts, Rhizoma Curculiginis 20 parts, Radix Rehmanniae Preparata 15 parts, Radix Aconiti 15 parts, Radix Aconiti Kusnezoffii 15 parts, Radix Angelicae Sinensis 15 parts, Radix Paeoniae Rubra 15 parts, Radix Codonopsis 15 parts, the Radix Astragali 15 parts, Radix Salviae Miltiorrhizae 15 parts, Caulis Spatholobi 15 parts, Fructus Liquidambaris 15 parts, Squama Manis 15 parts, Radix Clematidis 15 parts, Cortex Cinnamomi 9 parts, Herba Asari 9 parts, Radix Saposhnikoviae 9 parts, Rhizoma Zingiberis 9 parts, Ramulus Cinnamomi 9 parts, Semen Sinapis Albae 6 parts.
The preparation method of the Chinese medicine composition of described treatment raynaud disease, comprises the following steps: according to described parts by weight weighting raw materials; The crude drug taken is pulverized, mixes, sterilized; With every bag of 200 grams of vacuum packagings.
The application of Chinese medicine composition in preparation treatment raynaud disease medicine of described treatment raynaud disease.
Usage and consumption: the Chinese medicine composition made conventionally is decocted into decoction, every day 1 pair, can decoct 3 times; The front decoction mixing decocted for 2 times, respectively takes 1 time sooner or later; The decoction decocted for 3rd time is poured in basin, fumigation and wash method affected part, every day 1 time, each fumigation and wash method 20-30 minute.
The beneficial effect that the present invention is compared with prior art had is: the present invention is under Traditional Chinese medical theory and clinical experience instruct, and chooses each crude drug and proportioning thereof, reaches effect of warming YANG to expel cold, blood circulation and channel invigorating, relieving spasm to stop pain; The present invention treats that raynaud disease has good effect, instant effect, has no side effect, treatment cost is low, the simple advantage of preparation method; Through clinical verification, it is 96.2% that the present invention treats raynaud disease effective percentage.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine composition for raynaud disease, be made up of the crude drug of following weight portion: 20 parts, Flos Carthami, Rhizoma Chuanxiong 20 parts, Fructus Aurantii 20 parts, Ramulus Mori 20 parts, Rhizoma Curculiginis 20 parts, Radix Rehmanniae Preparata 15 parts, Radix Aconiti 15 parts, Radix Aconiti Kusnezoffii 15 parts, Radix Angelicae Sinensis 15 parts, Radix Paeoniae Rubra 15 parts, Radix Codonopsis 15 parts, the Radix Astragali 15 parts, Radix Salviae Miltiorrhizae 15 parts, Caulis Spatholobi 15 parts, Fructus Liquidambaris 15 parts, Squama Manis 15 parts, Radix Clematidis 15 parts, Cortex Cinnamomi 9 parts, Herba Asari 9 parts, Radix Saposhnikoviae 9 parts, Rhizoma Zingiberis 9 parts, Ramulus Cinnamomi 9 parts, Semen Sinapis Albae 6 parts.
Its preparation method comprises the following steps: according to described parts by weight weighting raw materials; The crude drug taken is pulverized, mixes, sterilized; With every bag of 200 grams of vacuum packagings.
Embodiment 2:
Treat a Chinese medicine composition for raynaud disease, be made up of the crude drug of following weight portion: 15 parts, Flos Carthami, Rhizoma Chuanxiong 15 parts, Fructus Aurantii 15 parts, Ramulus Mori 15 parts, Rhizoma Curculiginis 15 parts, Radix Rehmanniae Preparata 12 parts, Radix Aconiti 12 parts, Radix Aconiti Kusnezoffii 12 parts, Radix Angelicae Sinensis 12 parts, Radix Paeoniae Rubra 12 parts, Radix Codonopsis 12 parts, the Radix Astragali 12 parts, Radix Salviae Miltiorrhizae 12 parts, Caulis Spatholobi 12 parts, Fructus Liquidambaris 12 parts, Squama Manis 12 parts, Radix Clematidis 12 parts, Cortex Cinnamomi 6 parts, Herba Asari 6 parts, Radix Saposhnikoviae 6 parts, Rhizoma Zingiberis 6 parts, Ramulus Cinnamomi 6 parts, Semen Sinapis Albae 3 parts.
Its preparation method comprises the following steps: according to described parts by weight weighting raw materials; The crude drug taken is pulverized, mixes, sterilized; With every bag of 200 grams of vacuum packagings.
Embodiment 3:
Treat a Chinese medicine composition for raynaud disease, be made up of the crude drug of following weight portion: 25 parts, Flos Carthami, Rhizoma Chuanxiong 25 parts, Fructus Aurantii 25 parts, Ramulus Mori 25 parts, Rhizoma Curculiginis 25 parts, Radix Rehmanniae Preparata 18 parts, Radix Aconiti 18 parts, Radix Aconiti Kusnezoffii 18 parts, Radix Angelicae Sinensis 18 parts, Radix Paeoniae Rubra 18 parts, Radix Codonopsis 18 parts, the Radix Astragali 18 parts, Radix Salviae Miltiorrhizae 18 parts, Caulis Spatholobi 18 parts, Fructus Liquidambaris 18 parts, Squama Manis 18 parts, Radix Clematidis 18 parts, Cortex Cinnamomi 12 parts, Herba Asari 12 parts, Radix Saposhnikoviae 12 parts, Rhizoma Zingiberis 12 parts, Ramulus Cinnamomi 12 parts, Semen Sinapis Albae 9 parts.
Its preparation method comprises the following steps: according to described parts by weight weighting raw materials; The crude drug taken is pulverized, mixes, sterilized; With every bag of 200 grams of vacuum packagings.
Experimental example:
One, clinical data: adopt the present invention to treat 52 routine raynaud disease patients altogether, women 33 example, male 19 example, the oldest 44 years old, minimum 22 years old of age.
Two, clinical symptoms: when cold stimulation or excited and psychentonia, pale and cyanosis appears in finger skin, finger tip has numbness, sends out cool and twinge, after warming, color of the leather becomes flushing, then have warm and swollen sense, then color of the leather recovers normal, and symptom also disappears thereupon.
Three, Therapeutic Method: the Chinese medicine composition made conventionally is decocted into decoction, every day 1 pair, can decoct 3 times; The front decoction mixing decocted for 2 times, respectively takes 1 time sooner or later; The decoction decocted for 3rd time is poured in basin, fumigation and wash method affected part, every day 1 time, each fumigation and wash method 20-30 minute.
Four, the standard of curative effect evaluation:
Cure: clinical sign disappears completely, follows up a case by regular visits to 2 years non-recidivists;
Effective: symptom, sign substantially disappear or obviously alleviate, follow up a case by regular visits to 2 years even persons that have mild episode, do not affect orthobiosis;
Take a turn for the better: symptom, Signs obviously alleviate, but outbreak does not change interval time, or symptom does not change, but duration of seizure interval is elongated;
Invalid: symptom and duration of seizure all do not change.
Five, model case:
1, Hu, female, 43 years old, suffers from raynaud disease 8 years, interval outbreak; This outbreak disease is seen: both hands interval is livid purple, and except left hand thumb, all the other finger finger tips all have ulcer; Body of the tongue is dim, and tongue is white, deep-thready pulse; Through Western medicine anti-inflammatory treatment, and through debridement treatment, ulcer surface is slightly healed, and sclerderm appears in affected part; Use 3 courses for the treatment of of Chinese medicine composition of the present invention, clinical symptom remission, ulcer surface heals, and sclerderm comes off, and follows up a case by regular visits to and has no recurrence in 2 years.
2, Liu so-and-so, female, 27 years old, within 2 years, cause frequently contacted cold water, caused both hands remaining finger except thumb often to become pale asphyxia in suffering from cold, and then transferred to livid purple, became flushing after must warm up, then recover normally; During outbreak, companion is numb sends out cool and acupuncture sample pain, and outbreak several every day or a few days are once; Summer takes a turn for the better, and enters the winter and then increases the weight of; Be diagnosed as raynaud disease; Fully recover after using 2 courses for the treatment of of Chinese medicine composition of the present invention, follow up a case by regular visits to and have no recurrence in 2 years.
Six, therapeutic outcome:
Adopt the present invention to treat raynaud disease patient 52 example altogether, through the treatment of 1-3 the course for the treatment of, cure 38 examples, account for 73.1%, effective 7 examples, account for 13.5%, and take a turn for the better 5 examples, accounts for 9.6%, invalid 2 examples, and account for 3.8%, effective percentage is 96.2%; Result shows, the present invention has good effect, instant effect, has no side effect, treatment cost is low, the simple advantage of preparation method.

Claims (4)

1. treat the Chinese medicine composition of raynaud disease for one kind, it is characterized in that: be made up of the crude drug of following weight portion: Flos Carthami 15-25 part, Rhizoma Chuanxiong 15-25 part, Fructus Aurantii 15-25 part, Ramulus Mori 15-25 part, Rhizoma Curculiginis 15-25 part, Radix Rehmanniae Preparata 12-18 part, Radix Aconiti 12-18 part, Radix Aconiti Kusnezoffii 12-18 part, Radix Angelicae Sinensis 12-18 part, Radix Paeoniae Rubra 12-18 part, Radix Codonopsis 12-18 part, Radix Astragali 12-18 part, Radix Salviae Miltiorrhizae 12-18 part, Caulis Spatholobi 12-18 part, Fructus Liquidambaris 12-18 part, Squama Manis 12-18 part, Radix Clematidis 12-18 part, Cortex Cinnamomi 6-12 part, Herba Asari 6-12 part, Radix Saposhnikoviae 6-12 part, Rhizoma Zingiberis 6-12 part, Ramulus Cinnamomi 6-12 part, Semen Sinapis Albae 3-9 part.
2. the Chinese medicine composition for the treatment of raynaud disease according to claim 1, is characterized in that: be made up of the crude drug of following weight portion: 20 parts, Flos Carthami, Rhizoma Chuanxiong 20 parts, Fructus Aurantii 20 parts, Ramulus Mori 20 parts, Rhizoma Curculiginis 20 parts, Radix Rehmanniae Preparata 15 parts, Radix Aconiti 15 parts, Radix Aconiti Kusnezoffii 15 parts, Radix Angelicae Sinensis 15 parts, Radix Paeoniae Rubra 15 parts, Radix Codonopsis 15 parts, the Radix Astragali 15 parts, Radix Salviae Miltiorrhizae 15 parts, Caulis Spatholobi 15 parts, Fructus Liquidambaris 15 parts, Squama Manis 15 parts, Radix Clematidis 15 parts, Cortex Cinnamomi 9 parts, Herba Asari 9 parts, Radix Saposhnikoviae 9 parts, Rhizoma Zingiberis 9 parts, Ramulus Cinnamomi 9 parts, Semen Sinapis Albae 6 parts.
3. the preparation method of the Chinese medicine composition for the treatment of raynaud disease according to claim 1 and 2, is characterized in that: comprise the following steps: according to described parts by weight weighting raw materials; The crude drug taken is pulverized, mixes, sterilized; With every bag of 200 grams of vacuum packagings.
4. the application of Chinese medicine composition in preparation treatment raynaud disease medicine for the treatment of raynaud disease according to claim 1 and 2.
CN201310333652.2A 2013-08-03 2013-08-03 Traditional Chinese medicine composition for treating raynaud disease Expired - Fee Related CN103341153B (en)

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105267899A (en) * 2014-06-19 2016-01-27 蒋世芬 Traditional Chinese medicine mixed medicine used for treating Reynolds disease
CN104436112A (en) * 2014-11-13 2015-03-25 黄志超 Medicine for treating raynaud disease
CN105561272A (en) * 2016-01-27 2016-05-11 赵俊 Traditional Chinese medicine preparation for relieving Reynolds disease and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101269141A (en) * 2008-05-08 2008-09-24 北京天科仁祥医药科技有限公司 Chinese medicinal composition for treating raynaud's disease and preparation method thereof
CN102357240A (en) * 2011-10-22 2012-02-22 宋涛 Traditional Chinese medicine for treating peripheral vascular functional disease of Raynaud disease
CN102697963A (en) * 2012-06-12 2012-10-03 尹燕 Traditional Chinese medicine composition for curing Raynaud's disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101269141A (en) * 2008-05-08 2008-09-24 北京天科仁祥医药科技有限公司 Chinese medicinal composition for treating raynaud's disease and preparation method thereof
CN102357240A (en) * 2011-10-22 2012-02-22 宋涛 Traditional Chinese medicine for treating peripheral vascular functional disease of Raynaud disease
CN102697963A (en) * 2012-06-12 2012-10-03 尹燕 Traditional Chinese medicine composition for curing Raynaud's disease

Non-Patent Citations (1)

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雷诺病中医辨证论治五法;张月等;《中华中医药杂志》;20100430;第25卷(第4期);第537-539页 *

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Inventor after: Sun Yujie

Inventor after: Yan Qian

Inventor before: Liu Jianfei

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Address after: Xu Wei Road 262100 Shandong city in Weifang Province, Anqiu City, No. 212

Patentee after: Sun Yujie

Patentee after: Yang Wenwen

Address before: Tu Shan Xi Lu Yuhui District 233000 Anhui city of Bengbu province No. 1709 COFCO Tu thermoelectric boiler workshop production department

Patentee before: Liu Jianfei

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