CN102697963A - Traditional Chinese medicine composition for curing Raynaud's disease - Google Patents

Abstract

A traditional Chinese medicine composition for curing Raynaud's disease is prepared from datura flower, radix semiaquilegiae, bauhinia seeds, safflower carthamus, szechuan lovage rhizome,radix aconiti, radix aconiti feri, lilac and corydalis tuber. The traditional Chinese medicine composition can be used for curing Raynaud's disease clinically.

Description

A kind of Chinese medicine composition of treating raynaud disease

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition of treating raynaud disease.

Background technology

Raynaud disease is claimed Raynaud phenomenon again, and raynaud disease is a kind of peripheral vascular disease that is the basis with the neural blood vessel dysfunction, under cold or nervous etc. stimulates; Suddenly refer to (toe) terminal arteriolar spasm, cause procedural pale, the cyanosis of acra skin, normal bilateral limbs symmetry is got involved; Characteristic during its outbreak is meant that (toe) portion skin color bleaches suddenly; Then become livid purplely, transfer flushing then to, be intermittent attack.See and toes are rare to point more.Outbreak is often from little finger of toe and the beginning of fourth finger point, and along with lesion growth extends to whole finger even metacarpus gradually, but the less morbidity of thumb is sent out bloated uncomfortable or other abnormal sensories of cold, numbness, twinge and acid with the part.When just sending out, mostly duration of seizure is about several minutes to half an hour to be spontaneous remission.When skin transfers flushing to, often, transfer normal color and luster then to burning sensation of pricking.If local warming when outbreak rubs to wipe and suffers from limb, brandish limbs etc., outbreak is stopped.Sx during disease progression, outbreak is frequent, and sustainable＞1 hour of at every turn showing effect needs sometimes brothers are immersed and could end in the warm water to show effect.Traditional medicine thinks that raynaud disease belongs to " arthromyodynia, cold syndrome " category.Modern medicine generally gives vasodilation, and with the symptoms such as IR of releasing vasospasm, microcirculation improvement, reduction peripheral vessels, but therapeutic effect is not good, and the state of an illness is prone to outbreak repeatedly.

Summary of the invention

The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, to the Chinese medicine composition of the treatment raynaud disease of human non-toxic side effect.

The objective of the invention is to realize like this,, utilize the unique property of medicine of Chinese medicine, adopt graceful sieve flower, Radix Semiaquilegiae, Semen Bauhiniae championii, Flos Carthami, Rhizoma Chuanxiong, Radix Aconiti, Radix Aconiti Kusnezoffii, Flos Caryophylli, Rhizoma Corydalis according to certain compatibility requirement, through being processed into according to Chinese medical theory.

Prepare Chinese medicine composition of the present invention and process graceful sieve flower 120-180 part, Radix Semiaquilegiae 40-60 part, Semen Bauhiniae championii 40-60 part, Flos Carthami 20-40 part, Rhizoma Chuanxiong 20-40 part, Radix Aconiti 20-40 part, Radix Aconiti Kusnezoffii 20-40 part, Flos Caryophylli 10-30 part, Rhizoma Corydalis 10-30 part by following raw material medicaments.

Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: graceful sieve is spent 150 parts, 50 parts of Radix Semiaquilegiaes, 50 parts of Semen Bauhiniae championiis, 30 parts on Flos Carthami, 30 parts of Rhizoma Chuanxiongs, 30 parts of Radix Aconitis, 30 parts of Radix Aconiti Kusnezoffii, 20 parts of Flos Caryophyllis, 20 parts of Rhizoma Corydalis.

The pharmacological action of Chinese medicine of the present invention is following:

Graceful sieve flower: suffering, temperature, poisonous.Return lung, Liver Channel.Smooth-going cough-relieving, narcotic analgesic, spasmolytic is only jerked.Be used for asthma and cough, rheumatic arthralgia, epilepsy, infantile convulsion, surgical anesthesia etc.

Radix Semiaquilegiae: sweet, little hardship, little suffering, cold.Return liver, spleen, urinary bladder channel.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.It is frightened to cure mainly children's's heat, epilepsy, carbuncle, furuncle, acute mastitis, scrofula etc.

Semen Bauhiniae championii: bitter, Xin Wen.Return liver, stomach warp.Promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling.Be used for stagnation of QI and blood, distending pain over the hypochondrium, gastric abscess, traumatic injury.

Flos Carthami: hot, warm.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Cure mainly the blood stasis amenorrhea, obstruction of qi in the chest and cardialgia ， lumps in the chest and abdomen, arthralgia etc.

Rhizoma Chuanxiong: hot, warm, return liver, gallbladder, heart channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for stagnation of QI and blood, rheumatic arthralgia.

Radix Aconiti: hot, bitter, temperature.GUIXIN, spleen, liver, kidney channel.Be used for anemofrigid-damp arthralgia, traumatic injury.

Radix Aconiti Kusnezoffii: hot, bitter, hot, big poison.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic, be used for anemofrigid-damp arthralgia, arthralgia, traumatic injury pain etc.

Flos Caryophylli: hot, warm.Return spleen, stomach, kidney channel.Warming middle-JIAO to send down the adverse QI, dispersing cold for relieving pain, warming the kidney to activate YANG.Be used for that gastrofrigid vomiting, coldness and pain in the epigastrium, impotence due to deficiency of the kidney, the acid of waist knee joint are cold, carbuncle of yin nature etc.

Rhizoma Corydalis: hot, bitter, warm.Return liver, stomach, the heart, lung, spleen channel.Invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, pain relieving.Be used for all pains of trusted subordinate's waist knee joint, menoxenia, traumatic injury etc.

Primary disease belongs to the traditional Chinese medical science " cold limbs ", " deadly cold hand and foot " category, because acra is a twelve regular channels negative and positive handing-over part, if a little less than the plain bromhidrosis blood deficiency of patient; Yang-energy is on the decline, promotes unablely, receives the it is attacked by the cold and evil acra again; Numbness resistance network road; So that QI-blood circulation is not smooth, can not reach in extremity, and the extremity tip loses in warm all can bring out primary disease.Control to be main method with benefiting vital QI and blood, dispelling cold by warming the meridian, blood circulation and channel invigorating.Graceful sieve flower is monarch drug among the present invention, and external has the effect of anti-inflammatory analgetic, can the narcotic analgesic antiinflammatory, microcirculation improvement, and Radix Semiaquilegiae detoxicating and resolving stagnation of pathogens, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis promoting blood circulation and stopping pain, Semen Bauhiniae championii, Radix Aconiti, Radix Aconiti Kusnezoffii dispelling wind and removing obstruction in the collateral, Flos Caryophylli removing obstruction in the collateral to relieve pain.Find that through clinical practice raynaud disease is had unique curative effect, all medicines are played blood circulation promoting and blood stasis dispelling altogether, detoxicating and resolving stagnation of pathogens, and eliminating dampness and dredging channels, the effect of anti-inflammatory analgetic reaches the purpose of treating raynaud disease.

Chinese medicine composition of the present invention was in 2007 to 2009 clinical observation raynaud disease 40 routine patients, and clinical report is following:

1, physical data

Among the 40 routine patients, women's 32 examples, male's 8 examples, age 22-45 year, the course of disease is many at 2 years to 5 years, 39 years old mean age.

2, diagnostic criteria

Reference " diagnosis and treatment of vasculitic disease (two) Raynaud phenomenon and raynaud disease " standard:

Cause outbreak when (1) cold or excited easily; (2) limbs symmetry morbidity; (3) cutaneous necrosis that has the limitation ischemic lesions to cause, shallow table and little; (4) get rid of secondary disease; (5) state of an illness continues not find any pathogenesis more than 2 years.

3, Therapeutic Method

3.1 prescription: graceful sieve flower 150g, Radix Semiaquilegiae 50g, Semen Bauhiniae championii 50g, Flos Carthami 30g, Rhizoma Chuanxiong 30g, Radix Aconiti 30g, Radix Aconiti Kusnezoffii 30g, Flos Caryophylli 20g, Rhizoma Corydalis 20g.

3.2 preparation and method for using: add water according to conventional ratio, boiled back 30 minutes, smoke afterwards earlier and wash, 1 dose of every day, every day 2 times, each 30-40 minute, 15 days was 1 course of treatment.

4, therapeutic outcome:

4.1 treatment evaluation criteria: with reference to " new Chinese medicine clinical research guideline (2002) "

Cure: the clinical sign complete obiteration, follow up a case by regular visits to 2 years not recidivists;

Produce effects: symptom, sign disappear basically or obviously alleviate, and following up a case by regular visits to 2 years idols has the slight author of sending out, and does not influence orthobiosis;

Improvement: symptom, Signs obviously alleviate, but outbreak not variation blanking time, or not variation of symptom, but duration of seizure is elongated at interval;

Invalid: symptom and duration of seizure are all less than changing.

4.2 result: among the 40 routine patients, 20 examples of fully recovering (50.0%), produce effects 13 examples (32.5%), invalid 2 examples of effective 5 examples (12.5%) (5%), total effective rate is 95%.

Model case

1, Zhang, the woman 28 years old, went to a doctor in 2007.The patient is because of washing clothes with cold water, catches sight of that both hands are pale promptly to be transferred to livid purplely, feels cold with numb sensation of pricking, and intermittent attack can reach several hours at every turn, whenever needs both hands to put into warm water can to alleviate, and hospital is diagnosed as raynaud disease.After diagnosing, body of the tongue is light red, tongue is thick partially in vain, stringy and tense pulse.Use medicine of the present invention, 1 dose of every day.Above-mentioned symptom disappears basically after using 2 courses of treatment continuously, consolidates 1 course of treatment then, and recovery from illness is followed up a case by regular visits to 2 years symptoms and do not seen recurrence.2, Liu, the woman 39 years old, went to a doctor in 2008.The patient finds in the winter time or anxious state of mind when big that it is pale that brothers refer to that (toe) becomes, and blue then pain is met warm or emotion can obtain alleviation when steady, once is diagnosed as raynaud disease in how tame medical institutions.State of an illness outbreak at a time when the prescription on individual diagnosis, every day 2～3 times, lingual surface is purple, is dispersed in petechia, and the Sublingual venation is purple dark, deep-thready pulse.Use medicine of the present invention, 1 dose of every day, use 1 course of treatment after, brothers refer to the more preceding minimizing of (toe) pain seizure frequency, consolidate 2 courses of treatment then, the symptom complete obiteration, follow up a case by regular visits to 2 years not the recurrence.

The specific embodiment

Below in conjunction with embodiment the present invention is further described, following this embodiment only is used to the present invention is described and the present invention is not limited.

Embodiment 1, and a kind of Chinese medicine composition of treating raynaud disease is by graceful sieve flower 150g, Radix Semiaquilegiae 50g, and Semen Bauhiniae championii 50g, Flos Carthami 30g, Rhizoma Chuanxiong 30g, Radix Aconiti 30g, Radix Aconiti Kusnezoffii 30g, Flos Caryophylli 20g, Rhizoma Corydalis 20g process.

Embodiment 2, and a kind of Chinese medicine composition of treating raynaud disease is by graceful sieve flower 120g, Radix Semiaquilegiae 40g, and Semen Bauhiniae championii 40g, Flos Carthami 20g, Rhizoma Chuanxiong 20g, Radix Aconiti 20g, Radix Aconiti Kusnezoffii 20g, Flos Caryophylli 10g, Rhizoma Corydalis 10g process.

Embodiment 3, and a kind of Chinese medicine composition of treating raynaud disease is by graceful sieve flower 180g, Radix Semiaquilegiae 60g, and Semen Bauhiniae championii 60g, Flos Carthami 40g, Rhizoma Chuanxiong 40g, Radix Aconiti 40g, Radix Aconiti Kusnezoffii 40g, Flos Caryophylli 30g, Rhizoma Corydalis 30g process.

Claims (2)

1. Chinese medicine composition of treating raynaud disease is characterized in that it is to be processed by following raw material medicaments:

Graceful sieve flower 120-180 part Radix Semiaquilegiae 40-60 part Semen Bauhiniae championii 40-60 part Flos Carthami 20-40 part Rhizoma Chuanxiong 20-40 part

Radix Aconiti 20-40 part Radix Aconiti Kusnezoffii 20-40 part Flos Caryophylli 10-30 part Rhizoma Corydalis 10-30 part.

2. Chinese medicine composition according to claim 1 is characterized in that it is to be processed by following raw material medicaments:

Graceful sieve is spent 30 parts of 30 parts of Rhizoma Chuanxiongs of 50 parts of Flos Carthamis of 50 parts of Semen Bauhiniae championiis of 150 parts of Radix Semiaquilegiaes

20 parts of 20 parts of Rhizoma Corydalis of 30 portions of Flos Caryophyllis of 30 portions of Radix Aconiti Kusnezoffii of Radix Aconiti.