CN102697963B - Traditional Chinese medicine composition for curing Raynaud's disease - Google Patents
Traditional Chinese medicine composition for curing Raynaud's disease Download PDFInfo
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- CN102697963B CN102697963B CN201210208526.XA CN201210208526A CN102697963B CN 102697963 B CN102697963 B CN 102697963B CN 201210208526 A CN201210208526 A CN 201210208526A CN 102697963 B CN102697963 B CN 102697963B
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Abstract
A traditional Chinese medicine composition for curing Raynaud's disease is prepared from datura flower, radix semiaquilegiae, bauhinia seeds, safflower carthamus, szechuan lovage rhizome,radix aconiti, radix aconiti feri, lilac and corydalis tuber. The traditional Chinese medicine composition can be used for curing Raynaud's disease clinically.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of raynaud disease.
Background technology
Raynaud disease claims again Raynaud phenomenon, raynaud disease is a kind ofly to take neural blood vessel dysfunction as basic peripheral vascular disease, under cold or nervous etc. stimulates, suddenly refer to the arteriolar spasm of (toe) end, cause procedural pale, the cyanosis of acra skin, normal bilateral limbs symmetry is got involved, feature during its outbreak refers to that (toe) portion skin color bleaches suddenly, then become livid purplely, then transfer flushing to, be intermittent attack.To point common, toes are rare.Outbreak often from little finger of toe and fourth finger point, along with lesion growth extends to even metacarpus of whole finger gradually, but the less morbidity of thumb, with part send out cool, numbness, twinge and sour swollen discomfort or other abnormal sensories.During onset, it is spontaneous remission that duration of seizure mostly is about several minutes to half an hour.When skin transfers flushing to, often, with burning sensation of pricking, then transfer normal color and luster to.If local warming when outbreak, rubs wiping suffering limb, brandish limbs etc., can make outbreak stop.During disease progression, symptom increases the weight of, and outbreak is frequent, and the sustainable > 1 hour of at every turn showing effect, needs brothers to immerse in warm water and could end to show effect sometimes.Traditional medicine thinks that raynaud disease belongs to " arthromyodynia, cold syndrome " category.Modern medicine generally gives vasodilation, and removing vasospasm, improve microcirculation, reduce the symptoms such as irritant reaction of peripheral vessels, but therapeutic effect is not good, and the state of an illness is outbreak repeatedly easily.
Summary of the invention
The object of the present invention is to provide the Chinese medicine composition of the treatment raynaud disease that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopts graceful sieve flower, Radix Semiaquilegiae, Semen Bauhiniae championii, Flos Carthami, Rhizoma Chuanxiong, Radix Aconiti, Radix Aconiti Kusnezoffii, Flos Caryophylli, Rhizoma Corydalis according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention and make graceful sieve flower 120-180 part, Radix Semiaquilegiae 40-60 part, Semen Bauhiniae championii 40-60 part, Flos Carthami 20-40 part, Rhizoma Chuanxiong 20-40 part, Radix Aconiti 20-40 part, Radix Aconiti Kusnezoffii 20-40 part, Flos Caryophylli 10-30 part, Rhizoma Corydalis 10-30 part by following raw material medicaments.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: graceful sieve is spent 150 parts, 50 parts of Radix Semiaquilegiaes, 50 parts of Semen Bauhiniae championiis, 30 parts, Flos Carthami, 30 parts of Rhizoma Chuanxiongs, 30 parts of Radix Aconitis, 30 parts of Radix Aconiti Kusnezoffii, 20 parts of Flos Caryophyllis, 20 parts of Rhizoma Corydalis.
The pharmacological action of Chinese medicine of the present invention is as follows:
Graceful sieve flower: pungent, temperature, poisonous.Return lung, Liver Channel.Smooth-going cough-relieving, narcotic analgesic, spasmolytic is only jerked.For asthma and cough, rheumatic arthralgia, epilepsy, infantile convulsion, surgical anesthesia etc.
Radix Semiaquilegiae: sweet, micro-hardship, micro-pungent, cold.Return liver, spleen, urinary bladder channel.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Cure mainly children's's heat frightened, epilepsy, carbuncle, furuncle, acute mastitis, scrofula etc.
Semen Bauhiniae championii: bitter, Xin Wen.Return liver, stomach warp.Promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling.For stagnation of QI and blood, distending pain over the hypochondrium, gastric abscess, traumatic injury.
Flos Carthami: pungent, warm.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Cure mainly blood stasis amenorrhea, obstruction of qi in the chest and cardialgia ， lumps in the chest and abdomen, arthralgia etc.
Rhizoma Chuanxiong: pungent, warm, return liver, gallbladder, heart channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For stagnation of QI and blood, rheumatic arthralgia.
Radix Aconiti: pungent, bitter, temperature.GUIXIN, spleen, liver, kidney channel.For anemofrigid-damp arthralgia, traumatic injury.
Radix Aconiti Kusnezoffii: pungent, bitter, hot, malicious greatly.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic, for anemofrigid-damp arthralgia, arthralgia, traumatic injury pain etc.
Flos Caryophylli: pungent, warm.Return spleen, stomach, kidney channel.Warming middle-JIAO to send down the adverse QI, dispersing cold for relieving pain, warming the kidney to activate YANG., carbuncle of yin nature cold for gastrofrigid vomiting, coldness and pain in the epigastrium, impotence due to deficiency of the kidney, the acid of waist knee joint etc.
Rhizoma Corydalis: acrid, bitter, warm.Return liver, stomach, the heart, lung, spleen channel.Invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, pain relieving.For all pains of trusted subordinate's waist knee joint, menoxenia, traumatic injury etc.
Primary disease belongs to the traditional Chinese medical science " cold limbs ", " deadly cold hand and foot " category, because acra is twelve regular channels negative and positive handing-over part, if patient's element body deficient qi and blood, yang-energy is on the decline, promotes unablely, is subject to again it is attacked by the cold and evil acra, Bi Zuluo road, so that QI-blood circulation is not smooth, can not reach in extremity, and extremity tip loses in warm all can bring out primary disease.Controlling when take benefiting vital QI and blood, dispelling cold by warming the meridian, blood circulation and channel invigorating is main method.In the present invention, graceful sieve flower is monarch drug, and external has the effect of anti-inflammatory analgetic, can narcotic analgesic antiinflammatory, improve microcirculation, Radix Semiaquilegiae detoxicating and resolving stagnation of pathogens, Flos Carthami, Rhizoma Chuanxiong, Rhizoma Corydalis promoting blood circulation and stopping pain, Semen Bauhiniae championii, Radix Aconiti, Radix Aconiti Kusnezoffii dispelling wind and removing obstruction in the collateral, Flos Caryophylli removing obstruction in the collateral to relieve pain.Through clinical practice, find, raynaud disease is had to unique curative effect, and all medicines are played blood circulation promoting and blood stasis dispelling altogether, detoxicating and resolving stagnation of pathogens, and eliminating dampness and dredging channels, the effect of anti-inflammatory analgetic, reaches the object for the treatment of raynaud disease.
Chinese medicine composition of the present invention was in 2007 to 2009 the routine patients of clinical observation raynaud disease 40, and clinical report is as follows:
1, physical data
In 40 routine patients, women's 32 examples, male's 8 examples, age 22-45 year, the course of disease is many at 2 years to 5 years, 39 years old mean age.
2, diagnostic criteria
Diagnosis and treatment (two) Raynaud phenomenon and raynaud disease > > standard with reference to < < vasculitic disease:
(1) cold or easily cause outbreak when excited; (2) limbs symmetry morbidity; (3) cutaneous necrosis that has limitation ischemic lesions to cause, shallow table and little; (4) get rid of secondary disease; (5) state of an illness continues more than 2 years, not find any pathogenesis.
3, Therapeutic Method
3.1 prescriptions: graceful sieve flower 150g, Radix Semiaquilegiae 50g, Semen Bauhiniae championii 50g, Flos Carthami 30g, Rhizoma Chuanxiong 30g, Radix Aconiti 30g, Radix Aconiti Kusnezoffii 30g, Flos Caryophylli 20g, Rhizoma Corydalis 20g.
3.2 methods of preparation and use: add water according to conventional ratio, boil latter 30 minutes, first smoke afterwards and wash, 1 dose of every day, every day 2 times, each 30-40 minute, 15 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 treatment evaluation criterias: with reference to < < new Chinese medicine guideline of clinical investigations (2002) > >
Cure: clinical sign disappears completely, follows up a case by regular visits to 2 years not recidivists;
Effective: symptom, sign substantially disappear or obviously alleviate, follow up a case by regular visits to and within 2 years, occasionally have the slight author of sending out, do not affect orthobiosis;
Improvement: symptom, Signs obviously alleviate, but outbreak not variation interval time, or not variation of symptom, but duration of seizure interval is elongated;
Invalid: symptom and duration of seizure are all less than changing.
4.2 results: in 40 routine patients, recovery from illness 20 examples (50.0%), effective 13 examples (32.5%), invalid 2 examples of effective 5 examples (12.5%) (5%), total effective rate is 95%.
Model case
1, Zhang, female, 28 years old, 2007 were medical.Patient is because washing clothes with cold water, catches sight of that both hands are pale transfers to livid purplely, feels cold with numb sensation of pricking, and intermittent attack can reach a few hours at every turn, often needs both hands to put into warm water can to alleviate, and hospital is diagnosed as raynaud disease.After diagnosing, body of the tongue is light red, tongue is partially thick in vain, stringy and tense pulse.Use medicine of the present invention, 1 dose of every day.After using 2 courses for the treatment of continuously, above-mentioned symptom disappears substantially, then consolidates 1 course for the treatment of, and recovery from illness, follows up a case by regular visits to 2 years symptoms and have no recurrence.2, Liu, female, 39 years old, 2008 were medical.When Finding case in the winter time or anxious state of mind is large, it is pale that brothers refer to that (toe) becomes, and blue pain, can obtain alleviation when chance warms up or emotion is steady then, and Zeng Duojia medical institutions are diagnosed as raynaud disease.State of an illness outbreak at a time when medical, every day 2～3 times, lingual surface is purple, is dispersed in petechia, and Sublingual venation is purple dark, deep-thready pulse.Use medicine of the present invention, 1 dose of every day, use after 1 course for the treatment of, brothers refer to before (toe) pain seizure frequency reduce, and then consolidate 2 courses for the treatment of, and symptom disappears completely, follow up a case by regular visits to not recurrence in 2 years.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, and a kind of Chinese medicine composition for the treatment of raynaud disease is by graceful sieve flower 150g, Radix Semiaquilegiae 50g, and Semen Bauhiniae championii 50g, Flos Carthami 30g, Rhizoma Chuanxiong 30g, Radix Aconiti 30g, Radix Aconiti Kusnezoffii 30g, Flos Caryophylli 20g, Rhizoma Corydalis 20g make.
Embodiment 2, and a kind of Chinese medicine composition for the treatment of raynaud disease is by graceful sieve flower 120g, Radix Semiaquilegiae 40g, and Semen Bauhiniae championii 40g, Flos Carthami 20g, Rhizoma Chuanxiong 20g, Radix Aconiti 20g, Radix Aconiti Kusnezoffii 20g, Flos Caryophylli 10g, Rhizoma Corydalis 10g make.
Embodiment 3, and a kind of Chinese medicine composition for the treatment of raynaud disease is by graceful sieve flower 180g, Radix Semiaquilegiae 60g, and Semen Bauhiniae championii 60g, Flos Carthami 40g, Rhizoma Chuanxiong 40g, Radix Aconiti 40g, Radix Aconiti Kusnezoffii 40g, Flos Caryophylli 30g, Rhizoma Corydalis 30g make.
Claims (2)
1. treat the Chinese medicine composition for external fumigation and washing of raynaud disease, it is characterized in that it is to be made by following raw material medicaments:
Flos Daturae 120-180 part Radix Semiaquilegiae 40-60 part Semen Bauhiniae championii 40-60 part Flos Carthami 20-40 part
Rhizoma Chuanxiong 20-40 part Radix Aconiti 20-40 part Radix Aconiti Kusnezoffii 20-40 part Flos Caryophylli 10-30 part
Rhizoma Corydalis 10-30 part.
2. the Chinese medicine composition for external fumigation and washing according to claim 1, is characterized in that it is to be made by following raw material medicaments:
30 parts of 30 parts of Rhizoma Chuanxiongs of 50 parts of Flos Carthamis of 50 parts of Semen Bauhiniae championiis of 150 parts of Radix Semiaquilegiaes of Flos Daturae
20 parts of 20 parts of Rhizoma Corydalis of 30 portions of Flos Caryophyllis of 30 portions of Radix Aconiti Kusnezoffii of Radix Aconiti.
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| CN102697963B true CN102697963B (en) | 2014-03-19 |
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| CN103341153B (en) * | 2013-08-03 | 2015-05-27 | 刘建飞 | Traditional Chinese medicine composition for treating raynaud disease |
| CN105267899A (en) * | 2014-06-19 | 2016-01-27 | 蒋世芬 | Traditional Chinese medicine mixed medicine used for treating Reynolds disease |
| CN105998869A (en) * | 2016-07-29 | 2016-10-12 | 王旭东 | Traditional Chinese medicine preparation for treating raynaud disease and preparation method thereof |
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| CN101002917B (en) * | 2006-11-04 | 2010-05-19 | 于曼秋 | Chinese medicine for treating thromboangitis obliterans |
| CN101347598A (en) * | 2007-07-22 | 2009-01-21 | 郭武军 | Liniment spray for bonesetting and pain-alleviating |
| CN101269141A (en) * | 2008-05-08 | 2008-09-24 | 北京天科仁祥医药科技有限公司 | Chinese medicinal composition for treating raynaud's disease and preparation method thereof |
| CN102114228B (en) * | 2011-02-16 | 2012-11-07 | 李军 | Traditional Chinese medicine preparation for externally treating cold-dampness arthralgia syndrome |
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