CN102114228B

CN102114228B - Traditional Chinese medicine preparation for externally treating cold-dampness arthralgia syndrome

Info

Publication number: CN102114228B
Application number: CN2011100384313A
Authority: CN
Inventors: 李军
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-02-16
Filing date: 2011-02-16
Publication date: 2012-11-07
Anticipated expiration: 2031-02-16
Also published as: CN102114228A

Abstract

The invention provides a traditional Chinese medicine preparation for externally treating cold-dampness arthralgia syndrome, relating to the field of Chinese medical treatment on traditional Chinese medicine arthralgia syndrome. The traditional Chinese medicine arthralgia syndrome belongs to current common diseases and frequently encountered diseases and is mainly characterized by pain, numbness, heaviness and unfavorable flexion and extension of muscles, bones and joints or even arthrocele and the like clinically. In the modern medicine, rheumatic arthritis, rheumatoid arthritis, gout, Raynaud's disease, ankylosing spondylitis, sciatica, osteoarthritis, hyperosteogeny and other degenerative changes belong to the field of arthralgia syndrome. The traditional Chinese medicine preparation for externally treating arthralgia syndrome has simple, convenient and easy paths, can avoid stimulation caused by alimentary tract administration, and can reduce toxic side effects of medicines. The traditional Chinese medicine prescription for externally treating cold-dampness arthralgia syndrome, which is provided by the invention, is prepared from american lopseed, clematis root, curcuma, argyi leaf, chuanxiong rhizome, safflower, mastic, myrrh, szechuan aconite and wild aconite, and has the functions of expelling wind and removing damness, activating blood circulation to dissipate blood stasis and eliminating cold to stop pain. The modern iontophoresis treatment technology is combined for treating arthralgia syndrome, thereby being favorable for the percutaneous absorption of the traditional Chinese medicine, increasing the effective utilization of the traditional Chinese medicine components, and acquiring a more satisfactory clinical treatment effect.

Description

A kind of Chinese medicine preparation of external treatment cold-damp arthromyodynia

The present invention relates to tcm field, is a kind of Chinese medicine preparation of treating the cold-dampness type arthromyodynia.

" arthromyodynia " head is shown in Huangdi's Internal Classics, is commonly encountered diseases, the frequently-occurring disease of tcm clinical practice, clinical with muscle, muscles and bones, joint ache, numb, weighing, joint stuffiness, even arthroncuss etc. are principal character.Degeneratioies such as the rheumatism of modern medicine, rheumatoid arthritis, gout, Raynand's disease, ankylosing spondylitis, sciatica, osteoarthritis, hyperostosis dirt all belong to " arthromyodynia " category.

The pathogeny of arthromyodynia many with wind, that cold, wet three gas cause the resistance of meridians numbness is relevant, just point out as far back as " element is asked the numbness opinion ": " wet three gas of wind and cold are mixed extremely, close and be numbness also.Its migratory BI-syndrome caused mainly by pathogenic wind, BI-syndrome caused mainly by pathogenic cold being called painful BI, dampness victor be damp arthralgia also.", clinical common cold, damp syndrome type.Therapeutic Method for arthromyodynia is a lot, summarizes to get up nothing more than internal treatment, external treatment, combination of inner and outside method three major types.Because the primary disease pathogeny is complicated, disease is changeful, is easy to repeatedly, so extremely ancient Chinese medicine doctor is paid attention to, the scholar has research more at all times, has accumulated rich experience, and constantly performance and perfect.

Treatment arthromyodynia western medicine commonly used is with the control acute attack at present, and it is main taking medicine for a long time, and toxic and side effects is obvious relatively, and the patient is difficult to withstand long term exposure, and lacks ideal therapy and medicine.But the Chinese medicine primary disease has characteristic and advantages such as method is many, effective, the little prolonged application of toxicity, a present focus that is just becoming clinical research.Wherein, with " medicine of external treatment, the i.e. medicine of treatment by oral administration of medicines; The reason of external treatment, the i.e. reason of treatment by oral administration of medicines " aspect the treatment arthromyodynia rich experience is being arranged for the Chinese medicine external treatment of theoretical basis.The traditional Chinese medical science is thought external therapy of Chinese herb in the affected part, can act on each system in the body through the relevant approach of one internal organs through the cave, and play the Accommodation of multisystem, many organs, too many levels.Modern study shows that the external treatment medicine also has effects such as adjustment system tissue organ function and body's immunity, to bring into play its indirect therapeutical effect except that direct entering blood circulation performance therapeutical effect.Because Chinese medicine external treatment route of administration is simple and easy to do, the stimulation that can avoid the digestive tract administration to cause reduces poisonous side effect of medicine, is easy to accepted by the patient, therefore has the excellent development potentiality.Facts have proved that Chinese medicine external treatment treatment arthromyodynia has demonstrated fully the treatment characteristic and the advantage of Chinese medicine.Now, in view of its sickness rate high, clinical in to cold-dampness type arthromyodynia demand and suddenly wait to research and develop the sure external therapy of Chinese herb preparation of a kind of curative effect more.

For realizing above-mentioned aim, the present invention has developed a kind of Chinese medicine decocting external treatment preparation specially, and it is with Herba speranskiae tuberculatae that its prescription is formed, Rhizoma Curcumae Longae, and Radix Clematidis, Folium Artemisiae Argyi, Rhizoma Chuanxiong, Flos Carthami, Olibanum, Myrrha, Radix Aconiti, the Radix Aconiti Kusnezoffii component is formed.This Chinese medicine preparation medicinal effects is remarkable, has no side effect.Preparation technology is simple, and convenient the application through clinical verification, is ideal cold-dampness type arthromyodynia treatment Chinese medicine preparation, can supply extensive use.

This Chinese medicine preparation has expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the effect of dispersing cold for relieving pain.Wherein, Herba speranskiae tuberculatae, Rhizoma Curcumae Longae, Radix Clematidis, but Folium Artemisiae Argyi promoting the flow of QI in the collateral by warming the meridian, expelling wind and removing dampness; Rhizoma Chuanxiong, Flos Carthami, Olibanum, Myrrha have the merit of blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain, and Radix Aconiti, Radix Aconiti Kusnezoffii be the key medicine of dispelling cold and removing dampness, removing obstruction in the collateral to relieve pain more.The experiment proof: Flos Carthami can improve the toleration of body to pain, alleviates the state of muscular tone, spasm, can improve the microcirculation of damaged tissue simultaneously, promotes the reparation of damaged tissue; The Chinese medicine of invigorating blood circulation all can be protected chondrocyte and the integrity of safeguarding cartilage, and the destruction and the character that delay collagen in the cartilage change, and suppress synovial membrane inflammation and hypertrophy, and the formation and development that prevents knee osteoarthritis is played an important role.Modern study thinks that Aconitum carmichjaelii Debx. not only has tangible antiinflammatory, analgesic activity to animal formaldehyde property and Ovum Gallus domesticus album property " arthritis ", also has the effect of adrenocortical hormone appearance.

Chinese medicine electron ion introductory technique is clinical in recent years practical a kind of drug osmotic method, and the unidirectional current drug iontotherapy not only can directly import the focus part with medicine, also can make local drug concentration keep higher level; And long action time, unidirectional current has effects such as antiinflammatory, analgesia, blood circulation promoting, adjusting vegetative nerve function simultaneously, and unidirectional current and medicine ion import and interact; Its curative effect is all than simple medicine or galvanic good effect, thereby makes its vasodilation, and blood flow is accelerated; Quicken the metabolism of tissue, improve the nutrition of tissue, reduce perineural irritability; Make muscle fiber lax, muscular tension descends, and the ductility of tissue increases; And increase its infiltration, thereby reach reduce inflammation, the purpose of detumescence, spasmolysis and analgesia, loosen adhesion and promotion tissue repair.

Combine Chinese medicine to carry out the treatment of arthromyodynia modern iontophoresis technology, help the Transdermal absorption of Chinese medicine, increase effective utilization of Chinese medicinal ingredients; Directly acupuncture point, meridians are stimulated ability relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and cold; The operation QI and blood; Easing joint movement reaches the purpose of regulating QI to relieve pain, can obtain gratifying curative effect.

The inventor is the basis with the theory of integrated Chinese and western medicine, adopts Chinese medicinal components to process the decocting preparation, and it contains the Chinese medicinal components by following proportioning: Herba speranskiae tuberculatae 300-500g; Rhizoma Curcumae Longae 100-300g, Radix Clematidis 200-400g, Folium Artemisiae Argyi 100-300g; Rhizoma Chuanxiong 200-400g, Flos Carthami 100-500g, Olibanum 100-300g; Myrrha 100-300g, Radix Aconiti 100-300g, Radix Aconiti Kusnezoffii 100-300g.

The optimum ratio of each drug component is in the preparation of the present invention: Herba speranskiae tuberculatae 400g, Rhizoma Curcumae Longae 150g, Radix Clematidis 200g, Folium Artemisiae Argyi 150g, Rhizoma Chuanxiong 200g, Flos Carthami 100g, Olibanum 100g, Myrrha 100g, Radix Aconiti 200g, Radix Aconiti Kusnezoffii 150g.

In addition, the proportioning of each drug component of preparation of the present invention also is preferably: Herba speranskiae tuberculatae 420g, Rhizoma Curcumae Longae 140g, Radix Clematidis 280g, Folium Artemisiae Argyi 140g, Rhizoma Chuanxiong 280g, Flos Carthami 140g, Olibanum 140g, Myrrha 140g, Radix Aconiti 140g, Radix Aconiti Kusnezoffii 140g.

This preparation of medicaments method: 1. weigh each medicine in the above-mentioned content range in proportion, with the component drug Herba speranskiae tuberculatae of corresponding proportioning, Radix Aconiti, Radix Aconiti Kusnezoffii; Rhizoma Chuanxiong, Flos Carthami, Olibanum, Myrrha; Rhizoma Curcumae Longae, Radix Clematidis, Folium Artemisiae Argyi; Tradition decocting 40 minutes, it is 100 milliliters medical plastic bag that the gained medicinal liquid is encapsulated into specification respectively, it is subsequent use to put into refrigerator cold-storage after the cooling.

Embodiment 1: this preparation of medicaments method: weigh each medicine in the above-mentioned content range in proportion, with the component drug Herba speranskiae tuberculatae of corresponding proportioning, Radix Aconiti, Radix Aconiti Kusnezoffii 1.; Rhizoma Chuanxiong, Flos Carthami, Olibanum, Myrrha; Rhizoma Curcumae Longae, Radix Clematidis, Folium Artemisiae Argyi; By the regulation decocting, the medicinal liquid of frying in shallow oil is encapsulated into special-purpose medical herb liquid plastic bag respectively with boiling machine, it is subsequent use to put into refrigerator cold-storage after the cooling.In clinical, after the used suction pad of medication iontophoresis is filled medicinal liquid naturally, place to import under the therapeutic electrode, spread on the affected part, the row tcm herbal ion imports treatment.

Embodiment 2:

Press the optimum ratio of each material medicine content (weight) of this medicament: Herba speranskiae tuberculatae 420g, Rhizoma Curcumae Longae 140g, Radix Clematidis 280g, Folium Artemisiae Argyi 140g, Rhizoma Chuanxiong 280g, Flos Carthami 140g, Olibanum 140g, Myrrha 140g, Radix Aconiti 140g, Radix Aconiti Kusnezoffii 140g.

The capable tcm herbal ion of this preparation of clinical practice imports treatment 380 routine arthromyodynia patients, once a day, treats 20 minutes at every turn, and 10 days is 1 course of treatment.The result: obvious effective rate is 73.9%, and effective percentage is 96.8%.

Wherein a typical case is: on May 18th, 2010, and a routine right knee osteoarthritis patient, row micro computer pain therapy, infrared ray pain therapy are imitated little.Use this preparation and adopt the intermediate frequency medicine leading therapy, medicinal liquid is soaked the negative electrode medicated cushion at every turn and place the affected part, the anode medicated cushion places offside, treats 20 minutes, and every day 1 time, 10 days is 1 course of treatment, and two weeks accused more.

Claims

1. the Chinese medicine preparation of an external treatment cold-damp arthromyodynia is to be processed by the Chinese medicinal components of following proportioning: Herba speranskiae tuberculatae 300-500g, Rhizoma Curcumae Longae 100-300g; Radix Clematidis 200-400g, Folium Artemisiae Argyi 100-300g, Rhizoma Chuanxiong 200-400g; Flos Carthami 100-500g, Olibanum 100-300g, Myrrha 100-300g; Radix Aconiti 100-300g, Radix Aconiti Kusnezoffii 100-300g, said preparation process tcm herbal ion importing preparation, patch, unguentum and smoke and wash preparation.

2. preparation according to claim 1, wherein said preparation is that tcm herbal ion imports preparation.

3. preparation according to claim 1, wherein the proportioning of each Chinese medicinal components is: Herba speranskiae tuberculatae 400g, Rhizoma Curcumae Longae 150g, Radix Clematidis 200g, Folium Artemisiae Argyi 150g, Rhizoma Chuanxiong 200g, Flos Carthami 100g, Olibanum 100g, Myrrha 100g, Radix Aconiti 200g, Radix Aconiti Kusnezoffii 150g.

4. preparation according to claim 1, wherein the proportioning of each Chinese medicinal components is: Herba speranskiae tuberculatae 420g, Rhizoma Curcumae Longae 140g, Radix Clematidis 280g, Folium Artemisiae Argyi 140g, Rhizoma Chuanxiong 280g, Flos Carthami 140g, Olibanum 140g, Myrrha 140g, Radix Aconiti 140g, Radix Aconiti Kusnezoffii 140g.

5. the method for preparing of preparation according to claim 2 is characterized in that: with the component drug Herba speranskiae tuberculatae of corresponding proportioning, Radix Aconiti, Radix Aconiti Kusnezoffii; Rhizoma Chuanxiong, Flos Carthami, Olibanum, Myrrha; Rhizoma Curcumae Longae, Radix Clematidis, Folium Artemisiae Argyi; By the regulation decocting, the medicinal liquid of frying in shallow oil is encapsulated into special-purpose medical herb liquid plastic bag respectively with boiling machine, it is subsequent use to put into refrigerator cold-storage after the cooling.

6. the method for preparing of preparation according to claim 5 after the used suction pad of medication iontophoresis is filled medicinal liquid naturally, places to import under the therapeutic electrode, spreads on the affected part, and the row tcm herbal ion imports treatment.