CN103536893A - Traditional Chinese medicine composition for treating Raynaud disease - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating Raynaud disease, which is prepared from Astragalus membranaceus, cassia twig, radix paeoniae alba, bauhinia seed, safflower carthamus, Angelica sinensis, ginger, radix aconiti agrestis, Syzygium aromaticum, fructus jujubae, Saposhnidoviae Radix and folium isatidis. Clinically, the traditional Chinese medicine composition can be used for treating Raynaud disease.

Description

A kind of Chinese medicine composition for the treatment of raynaud disease

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of raynaud disease.

Background technology

Raynaud disease claims again Raynaud's disease, is the acra arteriolospasm disease causing owing to arranging the sympathetic nerve function disorder of peripheral vessels.Mainly due to cold stimulation or the lower morbidity of the factor such as excited impact, show as outbreak position and be the change of, cyanosis pale with paroxysmal extremity acra skin color intermittence and flushing.Raynaud disease can belong to the category of Chinese medicine " arthromyodynia ", " brothers are fainted cold ".The traditional Chinese medical science thinks that raynaud disease is that yang-energy can not reach four ends outward, sends out cool therefore have.Qi depression to blood stasis, blood stasis blocks meridians, therefore there is purple dark sign.Anxious state of mind in addition, anger impairing the liver, the liver failing to maintain the normal flow of QI, also can cause the stagnation of QI not all right, blood stasis four ends.Or golden sword hinders, blood stasis stops gathering, and acra blood vessels retardance etc. also can be brought out primary disease.

Summary of the invention

The object of the present invention is to provide the Chinese medicine composition of the treatment raynaud disease that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.

The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt the Radix Astragali, Ramulus Cinnamomi, the Radix Paeoniae Alba, Semen Bauhiniae championii, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Zingiberis Recens, Radix Aconiti Kusnezoffii, Flos Caryophylli, Fructus Jujubae, Radix Saposhnikoviae, Folium Isatidis according to certain compatibility requirement, through being processed into.

Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: Radix Astragali 30-50 part, Ramulus Cinnamomi 30-50 part, Radix Paeoniae Alba 30-50 part, Semen Bauhiniae championii 30-50 part, Flos Carthami 20-40 part, Radix Angelicae Sinensis 20-40 part, Rhizoma Zingiberis Recens 10-30 part, Radix Aconiti Kusnezoffii 10-30 part, Flos Caryophylli 10-30 part, Fructus Jujubae 10-30 part, Radix Saposhnikoviae 5-15 part, Folium Isatidis 5-15 part.

Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 40 parts of the Radixs Astragali, 40 parts of Ramulus Cinnamomi, 40 parts of the Radix Paeoniae Albas, 40 parts of Semen Bauhiniae championiis, 30 parts, Flos Carthami, 30 parts of Radix Angelicae Sinensis, 20 parts, Rhizoma Zingiberis Recens, 20 parts of Radix Aconiti Kusnezoffii, 20 parts of Flos Caryophyllis, 20 parts, Fructus Jujubae, 10 parts of Radix Saposhnikoviaes, 10 parts of Folium Isatidiss.

The pharmacological action of Chinese medicine of the present invention is as follows:

The Radix Astragali: sweet, warm, return lung, spleen channel.Benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening.For diarrhea due to hypofunction of the spleen, wait the card of all Qi and blood deficiencies.

Ramulus Cinnamomi: pungent, sweet, warm, GUIXIN, lung, urinary bladder channel.Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI.For anemofrigid cold, congealing cold with blood stasis, phlegm retention, syndrome of water-retention.

The Radix Paeoniae Alba: bitter, sour, be slightly cold, return liver, spleen channel.Nourish blood and seek, relieving spasm to stop pain, yin fluid astringing suppressing the hyperactive liver.Cure mainly blood deficiency cold and heat, epigastric pain, has a headache dizzy.

Semen Bauhiniae championii: bitter, Xin Wen.Return liver, stomach warp.Promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling.For stagnation of QI and blood, distending pain over the hypochondrium, gastric abscess, traumatic injury.

Flos Carthami: pungent, warm.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Cure mainly blood stasis amenorrhea, obstruction of qi in the chest and cardialgia ， lumps in the chest and abdomen, arthralgia etc.

Radix Angelicae Sinensis: sweet, pungent, warm, return liver, the heart, spleen channel.Enrich blood, invigorate blood circulation, regulating menstruation, pain relieving.For heart-liver blood deficiency, ulcer sores.

Rhizoma Zingiberis Recens: pungent, warm.Return lung, stomach, spleen channel.Expelling cold and relieving exterior syndrome, stopping nausea and vomiting by lowering the adverse flow of QI, preventing phlegm from forming and stopping coughing.For anemofrigid cold, fever with aversion to cold, headache nasal obstruction, vomiting, distension, have loose bowels etc.

Radix Aconiti Kusnezoffii: pungent, bitter, hot, malicious greatly.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic, for anemofrigid-damp arthralgia, arthralgia, traumatic injury pain etc.

Flos Caryophylli: pungent, warm.Return spleen, stomach, kidney channel.Warming middle-JIAO to send down the adverse QI, dispersing cold for relieving pain, warming the kidney to activate YANG., carbuncle of yin nature cold for gastrofrigid vomiting, coldness and pain in the epigastrium, impotence due to deficiency of the kidney, the acid of waist knee joint etc.

Fructus Jujubae: sweet, warm.Return spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relaxes the property of medicine.For insufficiency of the spleen anorexia and loose stool, fatigue and weakness, blood deficiency and yellow complexion and women's internal organs, mind is uneasy, protection healthy energy etc.

Radix Saposhnikoviae: pungent, sweet, tepor.Return bladder, liver, spleen channel.Deliver loose wind, removing dampness to relieve pain, relieving convulsion, antidiarrheal.For headache due to common cold, rubella pruritus, rheumatic arthralgia, tetanus card etc.

Folium Isatidis: bitter, cold.Return liver, the heart, stomach, spleen channel.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.For the high hot excessive thirst of calentura, coma, macule, spits blood, epistaxis, jaundice, dysentery etc.

Chinese medicine composition of the present invention was in 2005 to 20012 the routine patients of clinical observation raynaud disease 55, and clinical report is as follows:

1, physical data

In 55 routine patients, women's 37 examples, male's 13 examples, age 20-48 year, the course of disease is many at 1 year to 3 years, 37.5 years old mean age.

2, diagnostic criteria

Diagnosis and treatment (two) Raynaud phenomenon and raynaud disease > > standard with reference to < < vasculitic disease:

(1) cold or easily cause outbreak when excited; (2) limbs symmetry morbidity; (3) cutaneous necrosis that has limitation ischemic lesions to cause, shallow table and little; (4) get rid of secondary disease; (5) state of an illness continues more than 2 years, not find any pathogenesis.

3, Therapeutic Method

3.1 prescriptions: Radix Astragali 40g, Ramulus Cinnamomi 40g, Radix Paeoniae Alba 40g, Semen Bauhiniae championii 40g, Flos Carthami 30g, Radix Angelicae Sinensis 30g, Rhizoma Zingiberis Recens 20g, Radix Aconiti Kusnezoffii 20g, Flos Caryophylli 20g, Fructus Jujubae 20g, Radix Saposhnikoviae 10g, Folium Isatidis 10g.

3.2 methods of preparation and use: add water according to conventional ratio, big fire turns little fire after boiling endures 30 minutes, and drop is first smoked afterwards and washed after going out medicinal liquid, 1 dose of every day, every day 2 times, each 30 minutes 10 days was 1 course for the treatment of.

4, therapeutic outcome:

4.1 treatment evaluation criterias: with reference to < < new Chinese medicine guideline of clinical investigations (2002) > >

Cure: clinical sign disappears completely, follows up a case by regular visits to 2 years not recidivists;

Effective: symptom, sign substantially disappear or obviously alleviate, follow up a case by regular visits to and within 2 years, occasionally have the slight author of sending out, do not affect orthobiosis;

Improvement: symptom, Signs obviously alleviate, but outbreak not variation interval time, or not variation of symptom, but duration of seizure interval is elongated;

Invalid: symptom and duration of seizure are all less than changing.

4.2 results: in 55 routine patients, 28 examples of fully recovering (50.9%), effective 16 examples (29.1%), invalid 4 examples of effective 7 examples (12.7%) (7.3%), total effective rate is 92.7%.

5. model case

5.1 Dong, female, 33 years old, patient was because washing clothes with cold water, caught sight of that both hands are pale transfers to livid purplely, felt cold with numb sensation of pricking, and intermittent attack can reach a few hours at every turn, often needs both hands to put into warm water can to alleviate, and hospital is diagnosed as raynaud disease.After diagnosing, body of the tongue is light red, tongue is partially thick in vain, stringy and tense pulse.Use medicine of the present invention, 1 dose of every day.After using 2 courses for the treatment of continuously, above-mentioned symptom disappears substantially, then consolidates 1 course for the treatment of, and recovery from illness, follows up a case by regular visits to symptom after 1 year and have no recurrence.

5.2 Mas, female, 42 years old, patient brothers referred to that (toe) is pale, and blue pain can obtain alleviation when chance warms up or emotion is steady, and Zeng Duojia medical institutions are diagnosed as raynaud disease.State of an illness outbreak at a time when medical, every day 2～3 times, lingual surface is purple, is dispersed in petechia, and Sublingual venation is purple dark, deep-thready pulse.Use medicine of the present invention, 1 dose of every day, use after 1 course for the treatment of, brothers refer to before (toe) pain seizure frequency reduce, and then consolidate 2 courses for the treatment of, and symptom disappears completely, follows up a case by regular visits to not recurrence after 1 year.

The specific embodiment

Embodiment 1, and a kind of Chinese medicine composition for the treatment of raynaud disease is to be made by Radix Astragali 30g, Ramulus Cinnamomi 30g, Radix Paeoniae Alba 30g, Semen Bauhiniae championii 30g, Flos Carthami 20g, Radix Angelicae Sinensis 20g, Rhizoma Zingiberis Recens 10g, Radix Aconiti Kusnezoffii 10g, Flos Caryophylli 10g, Fructus Jujubae 10g, Radix Saposhnikoviae 5g, Folium Isatidis 5g.

Embodiment 2, and a kind of Chinese medicine composition for the treatment of raynaud disease is to be made by Radix Astragali 40g, Ramulus Cinnamomi 40g, Radix Paeoniae Alba 40g, Semen Bauhiniae championii 40g, Flos Carthami 30g, Radix Angelicae Sinensis 30g, Rhizoma Zingiberis Recens 20g, Radix Aconiti Kusnezoffii 20g, Flos Caryophylli 20g, Fructus Jujubae 20g, Radix Saposhnikoviae 10g, Folium Isatidis 10g.

Embodiment 3, and a kind of Chinese medicine composition for the treatment of raynaud disease is to be made by Radix Astragali 50g, Ramulus Cinnamomi 50g, Radix Paeoniae Alba 50g, Semen Bauhiniae championii 50g, Flos Carthami 40g, Radix Angelicae Sinensis 40g, Rhizoma Zingiberis Recens 30g, Radix Aconiti Kusnezoffii 30g, Flos Caryophylli 30g, Fructus Jujubae 30g, Radix Saposhnikoviae 15g, Folium Isatidis 15g.

Claims (2)

1. treat a Chinese medicine composition for raynaud disease, it is characterized in that it is to be made by following raw material medicaments:

Radix Astragali 30-50 part, Ramulus Cinnamomi 30-50 part, Radix Paeoniae Alba 30-50 part, Semen Bauhiniae championii 30-50 part, Flos Carthami 20-40 part, Radix Angelicae Sinensis 20-40 part, Rhizoma Zingiberis Recens 10-30 part, Radix Aconiti Kusnezoffii 10-30 part, Flos Caryophylli 10-30 part, Fructus Jujubae 10-30 part, Radix Saposhnikoviae 5-15 part, Folium Isatidis 5-15 part.

2. Chinese medicine composition according to claim 1, is characterized in that it is to be made by following raw material medicaments:

40 parts of the Radixs Astragali, 40 parts of Ramulus Cinnamomi, 40 parts of the Radix Paeoniae Albas, 40 parts of Semen Bauhiniae championiis, 30 parts, Flos Carthami, 30 parts of Radix Angelicae Sinensis, 20 parts, Rhizoma Zingiberis Recens, 20 parts of Radix Aconiti Kusnezoffii, 20 parts of Flos Caryophyllis, 20 parts, Fructus Jujubae, 10 parts of Radix Saposhnikoviaes, 10 parts of Folium Isatidiss.