CN102085347B - Traditional Chinese medicine composition for dispelling rheumatism - Google Patents

Traditional Chinese medicine composition for dispelling rheumatism Download PDF

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CN102085347B
CN102085347B CN2011100050026A CN201110005002A CN102085347B CN 102085347 B CN102085347 B CN 102085347B CN 2011100050026 A CN2011100050026 A CN 2011100050026A CN 201110005002 A CN201110005002 A CN 201110005002A CN 102085347 B CN102085347 B CN 102085347B
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radix
rhizoma
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王凤
姜军科
李健
朱艳
江和训
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王凤
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Abstract

The invention relates to a traditional Chinese medicine composition for dispelling rheumatism, which is composed of raw medicinal materials by weight: 10 to 30 grams of monkshood, 5 to 15 grams of dry ginger, 5 to 15 grams of cassia twig, 5 to 15 grams of fried atractylodes, 5 to 15 grams of ramulus mori, 6 to 10 grams of notopterygium root, 6 to 10 grams of levisticum, 6 to 10 grams of rhizoma alismatis, 6 to 10 grams of ooria cocos, 5 to 15 grams of radix codonopsis, 5 to 15 grams of cultivated land, 5 to 15 grams of cudweed herb, 3 to 7 grams of frankincense, 3 to 7 grams of myrrh, 1 to 2 centipedes, 5 to 7 grams of scorpion, 1 to 2 agkistrodons, 5 to 15 grams of licorice and 5 to 15 jujubes. Various plant and animal medicines which are mild and have little toxic and side effect are adopted as raw materials, so that the composition of the invention has the advantages of safety, reliability, simple preparation, wide medicine source, low cost and good curative effect. By clinical verification, 80 patients are treated and the effective rate reaches to 90%.

Description

A kind of Chinese medicine composition of expelling wind and dampness
Technical field
The present invention relates to a kind of pharmaceutical preparation of not confirming structure of traditional herbal medicines, especially a kind of Chinese medicine composition of treating rheumatismal expelling wind and dampness.
Background technology
The wet three gas heterozygosis of wind and cold are called numbness, refer to wind and the wet two kinds of pathogenic factor disease due to combining.Cause pain because involve the joint mostly, so rheumatism one speech is used till today always.Rheumatism is the abbreviation of rheumatism in the medical concept in modern times, and general reference influences BJM and surrounding soft tissue thereof, like a big group disease such as synovial bursa, tendon, fascia, blood vessel, nerve.Its clinical symptoms is: play ankylosis, arthroncus and tenderness in arthralgia, morning, the severe patient joint deformity with dysfunction appears.At present, doctor trained in Western medicine mainly is with antipyretic-antalgic, antiinflammatory to this group treatment of diseases of rheumatism, and relief of symptoms is a primary and foremost purpose, and selects NSAID for use, like Hull gram bone pain medicine plaster, diclofenac, mobic, happy pine, day Xin Lide, celecoxib, Wan Luo etc.But adopt the western medicine rheumatism to exist the deficiency that side effect is big, cure the symptoms, not the disease.
The traditional Chinese medical science is thought rheumatismal generation, and is main and weakened body resistance, heresy is invaded and the turbid congestion of expectorant is relevant.When the human righteousness was not enough, wind, cold, wet, hot exopathogen invasion and attack between numbness resistance muscle, joint, the meridians, caused QI-blood circulation not smooth, muscle muscles and bones arthralgia, numbness then occurred, that exhibition is stretched is unfavorable, even arthroncus, scorching hot, lopsided.
Chinese traditional treatment rheumatism, rheumatoid, with expelling wind and dampness, removing obstruction in the collateral to relieve pain, relaxing muscles and tendons to promote blood circulation, it is main improving autoimmunity, carries out dialectical prescription compatibility, to reach the purpose of treating both the principal and secondary aspects of a disease.
Summary of the invention
Exist the deficiency that side effect is big, cure the symptoms, not the disease in order to overcome prior art western medicines in treatment rheumatism, a kind of simple and convenient preparation, wide, the good effect in medicine source of providing of the present invention, cost is low, the Chinese medicine composition of the expelling wind and dampness that toxic and side effects is little.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition of expelling wind and dampness is characterized in that: be made up of following materials of weight proportions medicine: Radix Aconiti Lateralis Preparata 10-30g, Rhizoma Zingiberis 5-15g, Ramulus Cinnamomi 5-15g; Rhizoma Atractylodis Macrocephalae (parched) 5-15g, Ramulus Mori 5-15g, Rhizoma Et Radix Notopterygii 6-10g, Radix Angelicae Pubescentis 6-10g; Rhizoma Alismatis 6-10g, Poria 6-10g, Radix Codonopsis 5-15g, Radix Rehmanniae Preparata 5-15g; Rhizoma Homalomenae 5-15g, Olibanum 3-7g, Myrrha 3-7g, Scolopendra 1-2 bar; Scorpio 5-7g, Agkistrodon 1-2 bar, Radix Glycyrrhizae 5-15g, Fructus Jujubae 5-15 piece.
Optimal technical scheme of the present invention is: a kind of Chinese medicine composition of expelling wind and dampness is characterized in that: be made up of following materials of weight proportions medicine: Radix Aconiti Lateralis Preparata 20g, Rhizoma Zingiberis 10g, Ramulus Cinnamomi 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g; Ramulus Mori 10g, Rhizoma Et Radix Notopterygii 8g, Radix Angelicae Pubescentis 8g, Rhizoma Alismatis 8g, Poria 8g; Radix Codonopsis 10g, Radix Rehmanniae Preparata 10g, Rhizoma Homalomenae 10g, Olibanum 5g, Myrrha 5g; 1 of Scolopendra, Scorpio 6g, 1 of Agkistrodon, Radix Glycyrrhizae 10g, 10 pieces in Fructus Jujubae.
In the Chinese medicine composition of the present invention:
Radix Aconiti Lateralis Preparata, hot, sweet, big heat.GUIXIN, kidney, spleen channel.Ability recuperating depleted YANG emergency treatment of collapse, warming the kidney to activate YANG, dispersing cold for relieving pain.Be used for excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, the cold extremities faint pulse, trusted subordinate's cold type of pain, cold-dysentery, the beriberi edema, anemofrigid-damp arthralgia, sexual impotence, cold womb, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, the disease of carbuncle of yin nature skin infection and all chronic diseaseses.
Rhizoma Zingiberis, acrid in the mouth, hot in nature.Return spleen, stomach, the heart, lung meridian.Warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention.
Ramulus Cinnamomi, hot, sweet, temperature.GUIXIN, lung, urinary bladder channel.The diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
Rhizoma Atractylodis Macrocephalae (parched), bitter, sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Rhizoma Atractylodis Macrocephalae (parched) spleen invigorating and middle effect strengthen.
Ramulus Mori, hardship, flat, go into lung, kidney two warps.But wind-damp dispelling, sharp joint, row aqueous vapor.Control anemofrigid-damp arthralgia, spasm of the limbs, beriberi edema, human body pruritus due to wind pathogen.
Rhizoma Et Radix Notopterygii, acrid in the mouth; Bitter; Warm in nature.Return bladder; Kidney channel.Diffusing exterior cold; Wind-damp dispelling; Sharp joint; Pain relieving.
Radix Angelicae Pubescentis, hot, bitter, tepor.Return liver, kidney, urinary bladder channel.Expelling wind and dampness; Dispersing cold for relieving pain.Be used for anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, the headache toothache.
Rhizoma Alismatis, sweet in the mouth; Light; Cold in nature.Return kidney; Urinary bladder channel.Promoting diuresis to eliminate damp pathogen; It is treating stranguria to expel the heat-evil.Main dysuria; The puckery pain of pyretic stranguria; The edema distension; Have loose bowels; Dizziness due to fluid-retention; Seminal emission.
Poria, the property slightly sweet flavor is flat, goes into the heart, lung, spleen channel.Has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can control dysuria, the edema distension, the phlegm retention cough with dyspnea, vomiting, malignant histocytosis is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.
Radix Codonopsis, nature and flavor are sweet, and are flat.Return spleen, lung meridian.The tool invigorating the spleen and replenishing QI, spleen invigorating lung benefiting function.
Radix Rehmanniae Preparata, sweet, tepor.Return liver, kidney channel.The yin nourishing of enriching blood, life essence-filling, marrow-benefitting.
Rhizoma Homalomenae, suffering, temperature, mild toxicity.Go into Liver Channel; Kidney channel; The stomach warp.But wind-damp dispelling; Relaxing muscles and tendons and activating QI and blood in the collateral; Pain relieving; Detumescence.Cure mainly rheumatic arthralgia; Podomere acid is educated; The muscles and bones flaccidity is soft; Traumatic injury; Stomachache; The carbuncle skin ulcer is swollen.
Olibanum, arduous, temperature.Go into the heart, liver, spleen channel.But regulating qi and activating blood, analgesic therapy chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Myrrha, bitter in the mouth is flat, nontoxic.Go into spleen, kidney two warps.Cure mainly traumatic injury, bones and muscles pain.Join Olibanum, promoting blood circulation to remove blood stasis, circulation of qi promoting Shujin.
Scolopendra, salty, hot, temperature.Poisonous.Return liver, spleen, lung meridian.Can relieve internal heat anticancer, relieving spasm by calming endogenous wind, move back inflammation and control skin ulcer.
Scorpio, suffering, flat; Poisonous.Return Liver Channel.Endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Be used for infantile convulsion, the tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Agkistrodon, sweet, salty, temperature; Poisonous.Return Liver Channel.Dispel the wind collateral dredging, relieving convulsion.Be used for rheumatoid arthritis stubborn, numbness contracture, middle air port is askew, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Radix Glycyrrhizae, property is flat, and sweet in the mouth is returned 12 warps.Detoxifcation arranged, eliminate the phlegm, pain relieving, spasmolytic be so that pharmacological action such as anticancer.On the traditional Chinese medical science, the Radix Glycyrrhizae invigorating the spleen and replenishing QI is grown and to be coughed lung moistening, and the emergency detoxifcation is in harmonious proportion hundred medicines.
Fructus Jujubae, sweet, temperature.Return spleen, stomach warp.But invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, takes expelling wind and dampness, removing obstruction in the collateral to relieve pain, the rule of treatment of relaxing muscles and tendons to promote blood circulation, selected medicament composing prescription, treating both the principal and secondary aspects of a disease.In this Chinese medicine composition, be monarch drug with the Radix Aconiti Lateralis Preparata, rise and mend usefulness fiery supporing yang, dispersing cold for relieving pain; Rhizoma Zingiberis, Ramulus Cinnamomi, Rhizoma Atractylodis Macrocephalae (parched), Ramulus Mori, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Alismatis, Poria, Radix Codonopsis, Radix Rehmanniae Preparata, Rhizoma Homalomenae, Olibanum, Myrrha are ministerial drug, have the effect of spleen invigorating lung benefiting, regulating qi and activating blood, relaxing muscles and tendons and activating QI and blood in the collateral; Scolopendra, Scorpio, Agkistrodon are adjuvant drug, play the usefulness of endogenous wind stopping spasmolytic, pain-alleviating and network vessel-freeing; Radix Glycyrrhizae, Fructus Jujubae are messenger drug, have invigorating the spleen and replenishing QI, tying-in mediation effect.The various crude drug that the present invention adopted are the plant and animal medicine that the property of medicine is gentle, toxic and side effects is little, and are safe and reliable, and simple and convenient preparation, and the medicine source is wide, and cost is low, good effect.Through clinical verification, treatment patient 80 examples, effective percentage reaches 94%.In therapeutic process, do not find untoward reaction.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further specified.
Embodiment 1
A kind of Chinese medicine composition of expelling wind and dampness is made up of following materials of weight proportions medicine: Radix Aconiti Lateralis Preparata 20g, Rhizoma Zingiberis 10g, Ramulus Cinnamomi 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g; Ramulus Mori 10g, Rhizoma Et Radix Notopterygii 8g, Radix Angelicae Pubescentis 8g, Rhizoma Alismatis 8g, Poria 8g; Radix Codonopsis 10g, Radix Rehmanniae Preparata 10g, Rhizoma Homalomenae 10g, Olibanum 5g, Myrrha 5g; 1 of Scolopendra, Scorpio 6g, 1 of Agkistrodon, Radix Glycyrrhizae 10g, 10 pieces in Fructus Jujubae.
Embodiment 2
A kind of Chinese medicine composition of expelling wind and dampness is made up of following materials of weight proportions medicine: Radix Aconiti Lateralis Preparata 10g, Rhizoma Zingiberis 15g, Ramulus Cinnamomi 5g, Rhizoma Atractylodis Macrocephalae (parched) 15g; Ramulus Mori 5g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 6g, Rhizoma Alismatis 10g, Poria 6g; Radix Codonopsis 15g, Radix Rehmanniae Preparata 5g, Rhizoma Homalomenae 15g, Olibanum 3g, Myrrha 7g; 1 of Scolopendra, Scorpio 7g, 1 of Agkistrodon, Radix Glycyrrhizae 15g, 5 pieces in Fructus Jujubae.
Embodiment 3
A kind of Chinese medicine composition of expelling wind and dampness is made up of following materials of weight proportions medicine: Radix Aconiti Lateralis Preparata 30g, Rhizoma Zingiberis 5g, Ramulus Cinnamomi 15g, Rhizoma Atractylodis Macrocephalae (parched) 5g; Ramulus Mori 15g, Rhizoma Et Radix Notopterygii 6g, Radix Angelicae Pubescentis 10g, Rhizoma Alismatis 6g, Poria 10g; Radix Codonopsis 5g, Radix Rehmanniae Preparata 15g, Rhizoma Homalomenae 5g, Olibanum 7g, Myrrha 3g; 2 of Scolopendras, Scorpio 5g, 2 of Agkistrodons, Radix Glycyrrhizae 5g, 15 pieces in Fructus Jujubae.
Embodiment 4
A kind of Chinese medicine composition of expelling wind and dampness is characterized in that, is made up of following materials of weight proportions medicine: Radix Aconiti Lateralis Preparata 15g, Rhizoma Zingiberis 13g, Ramulus Cinnamomi 6g, Rhizoma Atractylodis Macrocephalae (parched) 13g; Ramulus Mori 6g, Rhizoma Et Radix Notopterygii 9g, Radix Angelicae Pubescentis 7g, Rhizoma Alismatis 9g, Poria 7g; Radix Codonopsis 13g, Radix Rehmanniae Preparata 8g, Rhizoma Homalomenae 14g, Olibanum 4g, Myrrha 6g; 1 of Scolopendra, Scorpio 7g, 1 of Agkistrodon, Radix Glycyrrhizae 13g, 7 pieces in Fructus Jujubae.
Embodiment 5
A kind of Chinese medicine composition of expelling wind and dampness is characterized in that, is made up of following materials of weight proportions medicine: Radix Aconiti Lateralis Preparata 25g, Rhizoma Zingiberis 7g, Ramulus Cinnamomi 14g, Rhizoma Atractylodis Macrocephalae (parched) 8g; Ramulus Mori 13g, Rhizoma Et Radix Notopterygii 7g, Radix Angelicae Pubescentis 9g, Rhizoma Alismatis 7g, Poria 9g; Radix Codonopsis 7g, Radix Rehmanniae Preparata 12g, Rhizoma Homalomenae 9g, Olibanum 6g, Myrrha 4g; 2 of Scolopendras, Scorpio 5g, 2 of Agkistrodons, Radix Glycyrrhizae 6g, 13 pieces in Fructus Jujubae.
The clinical efficacy of the Chinese medicine composition of expelling wind and dampness of the present invention is summed up:
One, clinical data: this Chinese medicine composition is applied to clinical treatment patient 80 examples, wherein male 34 examples, and women 46 examples, its age is at 30-75 between year, course of disease 1-15.
Two, diagnostic criteria: the RA diagnostic criteria of revising in 1987 according to American Rheumatism Association.
Three, usage and dosage and points for attention: during clinical practice, can take the circumstances into consideration to increase and decrease drug component and consumption according to patient's body weight and age.The material medicine of this Chinese medicine composition is gone ahead of the rest Radix Aconiti Lateralis Preparata, Scolopendra, Scorpio and Agkistrodon fried 15~20 minutes by the fried water consumption of Chinese medicine; Mixed with Rhizoma Zingiberis, Ramulus Cinnamomi, Rhizoma Atractylodis Macrocephalae (parched), Ramulus Mori, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Alismatis, Poria, Radix Codonopsis, Radix Rehmanniae Preparata, Rhizoma Homalomenae, Radix Glycyrrhizae and Fructus Jujubae fried 30-40 minute then, added Olibanum and Myrrha at last 10~15 minutes.Leaching medicinal liquid 200ml takes 100ml at every turn, every day 2 times.Be fried sticky, the pungent and cold and cool food of two weeks period in a medicine diet one course of treatment.
Four, therapeutic effect: in this clinical observation case, 75 routine patients' symptom makes moderate progress after 1 course of treatment of taking medicine, and laboratory indexes takes a turn for the better; Take medicine after 2-3 the course of treatment, 36 routine patient's functions are normal or near normal, laboratory indexes is normal, can participate in moderate physical work or operate as normal, follow up a case by regular visits to follow the tracks of and do not have repeatedly.Other 5 examples are invalid
Five, typical case:
With model case, further specify the clinical efficacy of this Chinese medicine composition below.
Case 1
The man, Lee, 42 years old, the workman, patient's readme limbs joint is ached heavyly clumsy during prescription on individual diagnosis, and brothers are heavy, inconvenient activity, numbness of the skin is meciless, through looking into, its white and greasy fur, pulse condition is slow.The heavy 86mm/h that has a blood test, anti-" 0 " (+), Western medicine diagnose rheumatic arthritis, tcm diagnosis is a rheumatic Bi syndrome.The Chinese medicine composition of taking a kind of expelling wind and dampness provided by the invention is after 2 courses of treatment, and symptom is alleviated basically, continues to take medicine 3 courses of treatment, and symptom disappears basically, and functional rehabilitation is normal.The heavy 15mm/h that has a blood test, anti-" 0 " 220 units.Follow up a case by regular visits to not recurrence so far.
Case 2
The man, Zhang, 67 years old, the patient suffered from rheumatism 5 years during prescription on individual diagnosis, limbs joint pain, pain has outdoor or migration, sharp ache, pain alleviated while getting warmth, pain increase in intensity under coldness, the joint can not be bent and stretched, and local color of the leather is not red, and that touches is not hot, and tongue fur is white, the pulse condition stringy and tense pulse.The heavy 60mm/h that has a blood test, anti-" 0 " (+), Western medicine diagnose rheumatic arthritis, tcm diagnosis is the wind and cold arthromyodynia.The Chinese medicine composition of taking a kind of expelling wind and dampness provided by the invention is after 2 courses of treatment, and sx continues to take medicine 3 courses of treatment, and function is near normal, and various physical and chemical inspection indexs are normal, can participate in slightly and work.
Case 3
The woman, Song, 44 years old, the daystart knee stiffness, muscular soreness, the stiff phenomenon in the movable back of appropriateness can alleviate.It cold arthralgia, limitation of movement is diagnosed as rheumatoid arthritis.
The Chinese medicine composition of taking a kind of expelling wind and dampness provided by the invention is after 1 course of treatment, and symptom is alleviated basically.Continue to take medicine 2 courses of treatment, symptom disappears basically, and functional rehabilitation is normal, and the physical and chemical inspection index is normal, follows up a case by regular visits to and does not see recurrence in 1 year.

Claims (2)

1. the Chinese medicine composition of an expelling wind and dampness is characterized in that: be made up of following materials of weight proportions medicine: Radix Aconiti Lateralis Preparata 10-30g, Rhizoma Zingiberis 5-15g, Ramulus Cinnamomi 5-15g, Rhizoma Atractylodis Macrocephalae (parched) 5-15g; Ramulus Mori 5-15g, Rhizoma Et Radix Notopterygii 6-10g, Radix Angelicae Pubescentis 6-10g, Rhizoma Alismatis 6-10g, Poria 6-10g; Radix Codonopsis 5-15g, Radix Rehmanniae Preparata 5-15g, Rhizoma Homalomenae 5-15g, Olibanum 3-7g, Myrrha 3-7g; Scolopendra 1-2 bar, Scorpio 5-7g, Agkistrodon 1-2 bar, Radix Glycyrrhizae 5-15g, Fructus Jujubae 5-15 piece.
2. the Chinese medicine composition of an expelling wind and dampness is characterized in that: be made up of following materials of weight proportions medicine: Radix Aconiti Lateralis Preparata 20g, Rhizoma Zingiberis 10g, Ramulus Cinnamomi 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g; Ramulus Mori 10g, Rhizoma Et Radix Notopterygii 8g, Radix Angelicae Pubescentis 8g, Rhizoma Alismatis 8g, Poria 8g; Radix Codonopsis 10g, Radix Rehmanniae Preparata 10g, Rhizoma Homalomenae 10g, Olibanum 5g, Myrrha 5g; 1 of Scolopendra, Scorpio 6g, 1 of Agkistrodon, Radix Glycyrrhizae 10g, 10 pieces in Fructus Jujubae.
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CN1327841C (en) * 2003-02-10 2007-07-25 沈恒 Novel compound antimalarial preparation method
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