CN103272155A - Chinese medicinal granules for preventing and treating ascariasis of pigs and preparation method thereof - Google Patents
Chinese medicinal granules for preventing and treating ascariasis of pigs and preparation method thereof Download PDFInfo
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Abstract
The invention discloses Chinese medicinal granules for preventing and treating ascariasis of pigs. The Chinese medicinal granules consist of the following components in parts by weight: 3 to 5 parts of cyrtomium rhizome, 2 to 4 parts of semen pharbitidis, 1 to 3 parts of pomegranate peel, and 1 to 2 parts of stemona. The Chinese medicinal granules are prepared by decocting and then adding sucrose; the Chinese medicinal granules for preventing and treating the ascariasis of the pigs are prepared through a reasonable formula of the traditional Chinese medicine, and have a function of preventing and treating the ascariasis of the pigs; the Chinese medicinal granules for preventing and treating the ascariasis of the pigs and the preparation method thereof are provided for the breeding industry; the Chinese medicinal granules have the characteristics of quick response and exact treatment effect, do not have medicament residue, toxic or side effect or medicament tolerance, and are convenient to transport and use; and the preparation method is simple, and is suitable for the requirement of large-scale industrial production.
Description
Technical field
The present invention relates to a kind of Chinese medicine granules and preparation method thereof, particularly relate to a kind of Chinese medicine granules of preventing and treating the ascaris suum disease and preparation method thereof.
Background technology
Ascaris suum parasitizes the digestive tract function obstacle of the pig that swine alimentary canal causes, and impaired development etc. are a class disease of feature, are one of capable main nematicide of present China large scale of pig farm field flow.Ascaris suum distributes popular wider, dependent territory source property parasite.Piglet susceptible and morbidity are serious.The morbidity pig cough, fervescence occur, breathes, and malnutrition becomes cad pig when serious; Analyse hemorrhage, the pneumonia of visible pig liver, can form nebulous milk spots in liver surface.The ascaris suum disease causes to pig industry and seriously influences, and antibiotic is mainly adopted in treatment that at present should disease, and a large amount of antibiotic application not only causes drug resistance, and can influence human beings'health.The present invention is pure Chinese medicinal preparation.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine granules of preventing and treating the ascaris suum disease.
Another technical problem that the present invention will solve is to provide the preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine granules of preventing and treating the ascaris suum disease is made up of Rhizoma Osmundae, Semen Pharbitidis, Pericarpium Granati and the Radix Stemonae, and it counts Rhizoma Osmundae 3-5 part by weight, Semen Pharbitidis 2-4 part, Pericarpium Granati 1-3 part; Radix Stemonae 1-2 part.
Preferably, the Chinese medicine granules of above-mentioned control ascaris suum disease is prepared by following method: concrete preparation process is as follows:
(1) takes by weighing Rhizoma Osmundae 3-5 part by weight, Semen Pharbitidis 2-4 part, Pericarpium Granati 1-3 part; Radix Stemonae 1-2 part is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract is dried the back under 70 ℃ of conditions and pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
Preferably, the Chinese medicine granules of above-mentioned control ascaris suum disease is by its parts by weight Rhizoma Osmundae 3-4 part, Semen Pharbitidis 3-4 part, Pericarpium Granati 2-3 part; Radix Stemonae 1-2 part.
Preferably, the Chinese medicine granules of above-mentioned control ascaris suum disease, by 4 parts of its parts by weight Rhizoma Osmundae, 3 parts of Semen Pharbitidiss, 2 parts of Pericarpium Granatis; 2 parts of the Radixs Stemonae.
The preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease, concrete preparation process is as follows:
(1) takes by weighing Rhizoma Osmundae 3-5 part by weight, Semen Pharbitidis 2-4 part, Pericarpium Granati 1-3 part; Radix Stemonae 1-2 part is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract is dried the back under 70 ℃ of conditions and pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
Preferably, extract powder and sucrose are by 1 part of its parts by weight extract powder, sucrose 2-7 part in the preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease, described step (3).
Preferably, extract powder and sucrose are by 1 part of its parts by weight extract powder, 2 parts of sucrose in the preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease, described step (3).
Compared with prior art, the invention has the beneficial effects as follows:
The Chinese medicine granules of above-mentioned control ascaris suum disease, with the Chinese medicine reasonable formula, function with control ascaris suum disease, for aquaculture provides a kind of Chinese medicine granules of preventing and treating the ascaris suum disease, it is outstanding to have curative effect, the characteristics of no drug residue, the problem that has no side effect, has no drug resistance, and convenient transportation, easy to use; Its preparation method is simple, is fit to requirements of large-scale industrial production.
The specific embodiment
Below in conjunction with specific embodiment the present invention is described in further detail.Should be appreciated that specific embodiment described herein only in order to explaining the present invention, and be not used in restriction the present invention.
Embodiment 1
A kind of Chinese medicine granules of preventing and treating the ascaris suum disease is made up of Rhizoma Osmundae, Semen Pharbitidis, Pericarpium Granati and the Radix Stemonae, Rhizoma Osmundae 3kg wherein, Semen Pharbitidis 2kg, Pericarpium Granati 1kg; Radix Stemonae 1kg.
The preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease, concrete preparation process is as follows:
(1) takes by weighing Rhizoma Osmundae 3kg, Semen Pharbitidis 2kg, Pericarpium Granati 1kg; Radix Stemonae 1kg is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 70 ℃ of conditions pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are by 1 part of its parts by weight extract powder, 2 parts of sucrose, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
Embodiment 2
A kind of Chinese medicine granules of preventing and treating the ascaris suum disease is made up of Rhizoma Osmundae, Semen Pharbitidis, Pericarpium Granati and the Radix Stemonae, Rhizoma Osmundae 5kg wherein, Semen Pharbitidis 4kg, Pericarpium Granati 3kg; Radix Stemonae 2kg.
The preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease, concrete preparation process is as follows:
(1) takes by weighing Rhizoma Osmundae 5kg, Semen Pharbitidis 4kg, Pericarpium Granati 3kg; Radix Stemonae 2kg is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 70 ℃ of conditions pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are by 1 part of its parts by weight extract powder, 7 parts of sucrose, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
Embodiment 3
A kind of Chinese medicine granules of preventing and treating the ascaris suum disease is made up of Rhizoma Osmundae, Semen Pharbitidis, Pericarpium Granati and the Radix Stemonae, 3kg wherein, Semen Pharbitidis 3kg, Pericarpium Granati 2kg; Radix Stemonae 1kg.
The preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease, concrete preparation process is as follows:
(1) takes by weighing 3kg, Semen Pharbitidis 3kg, Pericarpium Granati 2kg; Radix Stemonae 1kg is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 70 ℃ of conditions pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are by 1 part of its parts by weight extract powder, 3 parts of sucrose, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
Embodiment 4
A kind of Chinese medicine granules of preventing and treating the ascaris suum disease is made up of Rhizoma Osmundae, Semen Pharbitidis, Pericarpium Granati and the Radix Stemonae, 4kg wherein, Semen Pharbitidis 4kg, Pericarpium Granati 3kg; Radix Stemonae 2kg.
The preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease, concrete preparation process is as follows:
(1) takes by weighing 4kg, Semen Pharbitidis 4kg, Pericarpium Granati 3kg; Radix Stemonae 2kg is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 70 ℃ of conditions pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are by 1 part of its parts by weight extract powder, 4 parts of sucrose, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
Embodiment 5
A kind of Chinese medicine granules of preventing and treating the ascaris suum disease is made up of Rhizoma Osmundae, Semen Pharbitidis, Pericarpium Granati and the Radix Stemonae, Rhizoma Osmundae 4kg wherein, Semen Pharbitidis 3kg, Pericarpium Granati 2kg; Radix Stemonae 2kg.
The preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease, concrete preparation process is as follows:
(1) takes by weighing Rhizoma Osmundae 4kg, Semen Pharbitidis 3kg, Pericarpium Granati 2kg; Radix Stemonae 2kg is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 70 ℃ of conditions pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are by 1 part of its parts by weight extract powder, 5 parts of sucrose, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
Embodiment 6
A kind of Chinese medicine granules of preventing and treating the ascaris suum disease is made up of Rhizoma Osmundae, Semen Pharbitidis, Pericarpium Granati and the Radix Stemonae, Rhizoma Osmundae 3kg wherein, Semen Pharbitidis 4kg, Pericarpium Granati 3kg; Radix Stemonae 2kg.
The preparation method of the Chinese medicine granules of above-mentioned control ascaris suum disease, concrete preparation process is as follows:
(1) takes by weighing Rhizoma Osmundae 3kg, Semen Pharbitidis 4kg, Pericarpium Granati 3kg; Radix Stemonae 2kg is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 70 ℃ of conditions pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are by 1 part of its parts by weight extract powder, 6 parts of sucrose, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
The described Chinese crude drug of one of embodiment 1-6 is the commercially available prod, and each amounts of components is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The described Chinese crude drug of embodiment 1-6 all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2010.
The composition principle of Chinese medicine granules of the present invention is: the Rhizoma Osmundae heat-clearing and toxic substances removing, and cooling blood for hemostasis, parasite killing Semen Pharbitidis removing water retention by purgation removes long-pending parasite killing; The Pericarpium Granati relieving diarrhea with astringents, parasite killing, astringing to arrest bleeding; Radix Stemonae nourishing the lung to arrest cough, parasite killing.All medicines share the enhancing insecticidal action, and nourishing the lung to arrest cough promotes polypide to discharge, Synergistic is remarkably productive to controlling control ascaris suum disease mutually, especially adopts embodiment 5 described proportionings, the effect of control ascaris suum disease is very remarkable, particularly is fit to the treatment of control ascaris suum disease.
The clinical trial example:
The usage of the Chinese medicine granules of above-mentioned control ascaris suum disease is: allow pig fasting 12 hours before the administration, allow pig freely drink in drinking-water the Chinese medicine granules mixing in the ratio of the described Chinese medicine granules of 10g in every 10kg water, being used in conjunction 3-5 days is a course for the treatment of.Oral back reaches the purpose for the treatment of disease by intestinal absorption.
In May in year, 100 pigs cough, fervescence occur, breathe in 500 pigs in certain pig farm, and feed intake descends, and spirit is depressed, dead pig occurs.Analyse hemorrhage, the pneumonia of visible pig liver, can form nebulous milk spots in liver surface, gather feces and detect the discovery worm's ovum, be diagnosed as ascariasis, satisfy the medicine with the embodiment of the invention 5, after the medication 3~5 days, do not compare with carrying out medication therapy groups, the cough sx, body temperature obviously reduces, feed intake increases, and worm's ovum is not found in the excrement inspection.
Above-mentioned detailed description of this a kind of Chinese medicine granules of preventing and treating the ascaris suum disease and preparation method thereof being carried out with reference to embodiment; be illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (7)
1. Chinese medicine granules of preventing and treating the ascaris suum disease, it is characterized in that: be made up of Rhizoma Osmundae, Semen Pharbitidis, Pericarpium Granati and the Radix Stemonae, it counts Rhizoma Osmundae 3-5 part by weight, Semen Pharbitidis 2-4 part, Pericarpium Granati 1-3 part; Radix Stemonae 1-2 part.
2. the Chinese medicine granules of control according to claim 1 ascaris suum disease is characterized in that: by following method preparation: concrete preparation process is as follows:
(1) takes by weighing Rhizoma Osmundae 3-5 part by weight, Semen Pharbitidis 2-4 part, Pericarpium Granati 1-3 part; Radix Stemonae 1-2 part is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract is dried the back under 70 ℃ of conditions and pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
3. the Chinese medicine granules of control ascaris suum disease according to claim 1 and 2 is characterized in that: by its parts by weight Rhizoma Osmundae 3-4 part, Semen Pharbitidis 3-4 part, Pericarpium Granati 2-3 part; Radix Stemonae 1-2 part.
4. the Chinese medicine granules of control according to claim 1 and 2 ascaris suum disease is characterized in that: by 4 parts of its parts by weight Rhizoma Osmundae, and 3 parts of Semen Pharbitidiss, 2 parts of Pericarpium Granatis; 2 parts of the Radixs Stemonae.
5. the preparation method of the Chinese medicine granules of the described control of claim 1 ascaris suum disease, it is characterized in that: concrete preparation process is as follows:
(1) takes by weighing Rhizoma Osmundae 3-5 part by weight, Semen Pharbitidis 2-4 part, Pericarpium Granati 1-3 part; Radix Stemonae 1-2 part is raw material;
(2) add the water of 10 times of amounts of medical material gross weight in the above-mentioned four flavor Chinese medicines, decocts 2 times, decocted 2 hours for the first time, decocted 1.5 hours for the second time, collecting decoction, filtration is got filtrate and is concentrated under 1.28,80 ℃ of conditions of relative density and obtains concentrated extract;
(3) step (2) gained concentrated extract is dried the back under 70 ℃ of conditions and pulverizes, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, with 85%(v/v) ethanol makes granule and crosses 10 mesh sieves, 60 ℃ of oven dry, after 10 mesh sieves namely.
6. according to the preparation method of the Chinese medicine granules of the described control ascaris suum disease of claim 5, it is characterized in that: extract powder and sucrose are by 1 part of its parts by weight extract powder, sucrose 2-7 part in the described step (3).
7. according to claim 5 or 6 described preparation methoies of preventing and treating the Chinese medicine granules of ascaris suum diseases, it is characterized in that: extract powder and sucrose are by 1 part of its parts by weight extract powder, 2 parts of sucrose in the described step (3).
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CN104256098A (en) * | 2014-10-15 | 2015-01-07 | 聊城大学 | Chinese herbal medicine feed additive for piglets and preparation method of additive |
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CN104256098A (en) * | 2014-10-15 | 2015-01-07 | 聊城大学 | Chinese herbal medicine feed additive for piglets and preparation method of additive |
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Application publication date: 20130904 |