CN103221524B - 用于浓缩omega-3脂肪酸的方法 - Google Patents

用于浓缩omega-3脂肪酸的方法 Download PDF

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Publication number
CN103221524B
CN103221524B CN201180055920.8A CN201180055920A CN103221524B CN 103221524 B CN103221524 B CN 103221524B CN 201180055920 A CN201180055920 A CN 201180055920A CN 103221524 B CN103221524 B CN 103221524B
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Prior art keywords
fatty acid
omega
fatty acids
concentrate
aqueous phase
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CN201180055920.8A
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Chinese (zh)
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CN103221524A (zh
Inventor
H.布雷维克
O.索尔斯塔德
F.O.利布诺
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Pronova Biopharma Norge AS
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Pronova Biopharma Norge AS
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    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/006—Refining fats or fatty oils by extraction
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08—Refining
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/48—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/50—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/003—Refining fats or fatty oils by enzymes or microorganisms, living or dead

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Fats And Perfumes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Extraction Or Liquid Replacement (AREA)
CN201180055920.8A 2010-09-24 2011-09-23 用于浓缩omega-3脂肪酸的方法 Active CN103221524B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38609610P 2010-09-24 2010-09-24
US61/386,096 2010-09-24
PCT/IB2011/002593 WO2012038833A1 (en) 2010-09-24 2011-09-23 Process for concentrating omega-3 fatty acids

Publications (2)

Publication Number Publication Date
CN103221524A CN103221524A (zh) 2013-07-24
CN103221524B true CN103221524B (zh) 2021-01-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180055920.8A Active CN103221524B (zh) 2010-09-24 2011-09-23 用于浓缩omega-3脂肪酸的方法

Country Status (12)

Country Link
US (1) US9145533B2 (enExample)
EP (1) EP2619298B1 (enExample)
JP (1) JP5946833B2 (enExample)
KR (1) KR101904392B1 (enExample)
CN (1) CN103221524B (enExample)
AU (1) AU2011306471B2 (enExample)
CA (1) CA2812305C (enExample)
CL (1) CL2013000792A1 (enExample)
ES (1) ES2700134T3 (enExample)
PE (1) PE20140202A1 (enExample)
SG (1) SG188626A1 (enExample)
WO (1) WO2012038833A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2682453B2 (en) † 2011-03-03 2023-03-22 Nissui Corporation Method of producing oil/fat comprising highly-unsaturated fatty acids by means of lipase
CN107050457A (zh) 2012-01-06 2017-08-18 翁特拉制药公司 游离酸形式的ω‑3多不饱和脂肪酸的富含dpa组合物
EP2846779A4 (en) 2012-05-07 2015-12-16 Omthera Pharmaceuticals Inc STATIN AND OMEGA-3 FATTY ACID COMPOSITIONS
CA3225865A1 (en) 2012-05-14 2013-11-21 Nissui Corporation Method for producing highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester with reduced environmental pollutants
EP2911657A4 (en) * 2012-10-23 2016-08-03 Univ Deakin METHOD OF LOWERING TRIGLYCERIDES
JP6234908B2 (ja) * 2013-09-30 2017-11-22 日清ファルマ株式会社 エイコサペンタエン酸及び／又はドコサヘキサエン酸含有組成物の製造方法
EP3066183A4 (en) * 2013-11-08 2017-09-27 Omega Protein Corporation Purification of dpa enriched oil
AU2015269307C1 (en) 2014-06-06 2019-10-03 Marine Ingredients, Llc Omega-3 compositions, dosage forms, and methods of use
CN107666904B (zh) * 2015-03-26 2022-02-01 提贝托·布鲁泽塞 多不饱和脂肪酸的纯化组合物、其制备方法及其用途
EP3313391A1 (en) 2015-06-26 2018-05-02 Pronova BioPharma Norge AS Composition for treatment of nafld
WO2017191821A1 (ja) * 2016-05-02 2017-11-09 日清ファルマ株式会社 高度不飽和脂肪酸含有組成物の製造方法
CN107162910B (zh) * 2017-05-19 2019-12-31 陕西源邦生物技术有限公司 从鱼油中制备高纯度epa-ee的方法
CN110709496A (zh) * 2017-06-14 2020-01-17 日清药业股份有限公司 含有高度不饱和脂肪酸的组合物的制造方法
EP3586641A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586642A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Ala enriched polyunsaturated fatty acid compositions
EP3586640A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
EP3586643A1 (en) 2018-06-21 2020-01-01 Nuseed Pty Ltd Dha enriched polyunsaturated fatty acid compositions
US11767491B2 (en) 2019-03-26 2023-09-26 Nisshin Pharma Inc. Eicosapentaenoic acid alkyl ester-containing composition and method for producing same
CN111085006A (zh) * 2019-12-24 2020-05-01 河北省地矿局第二地质大队 一种环境中有机污染物提取工艺
TWI751577B (zh) * 2020-06-05 2022-01-01 中化合成生技股份有限公司 利用連續式反應器以純化多不飽和脂肪酸之方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2839276B2 (ja) * 1989-01-23 1998-12-16 日本分光工業株式会社 超臨界流体抽出・分離方法及び装置
JPH06248289A (ja) * 1993-02-27 1994-09-06 Nippon Suisan Kaisha Ltd 高度不飽和脂肪酸類を選択的に分離回収する方法
JPH07242895A (ja) * 1993-03-16 1995-09-19 Ikeda Shiyotsuken Kk 高純度エイコサペンタエン酸又はその低級アルコールエステルの分離精製法
JP2001240893A (ja) * 1999-12-20 2001-09-04 Q P Corp エイコサペンタエン酸又はその誘導体の精製方法
JP2001335794A (ja) * 2000-05-29 2001-12-04 Q P Corp ドコサヘキサエン酸又はその誘導体の精製方法
CN1223664C (zh) * 2003-07-21 2005-10-19 天津市医药科学研究所 从鱼油中提纯高含量dha、epa的方法
JP5503856B2 (ja) * 2008-09-10 2014-05-28 キユーピー株式会社 高度不飽和脂肪酸誘導体の取得方法
US8173826B2 (en) * 2009-06-17 2012-05-08 Chevron U.S.A. Inc. Enrichment of monounsaturated acids/esters in vegetable oil—or animal fat-based feedstock using metal salts dissolved in ionic liquids

Also Published As

Publication number Publication date
CL2013000792A1 (es) 2013-09-23
EP2619298B1 (en) 2018-09-12
AU2011306471B2 (en) 2016-06-02
WO2012038833A1 (en) 2012-03-29
ES2700134T3 (es) 2019-02-14
CA2812305C (en) 2019-08-20
US20130317241A1 (en) 2013-11-28
JP5946833B2 (ja) 2016-07-06
PE20140202A1 (es) 2014-03-15
CA2812305A1 (en) 2012-03-29
US9145533B2 (en) 2015-09-29
CN103221524A (zh) 2013-07-24
EP2619298A1 (en) 2013-07-31
KR20130099270A (ko) 2013-09-05
EP2619298A4 (en) 2015-08-19
KR101904392B1 (ko) 2018-10-05
JP2013542927A (ja) 2013-11-28
SG188626A1 (en) 2013-04-30
AU2011306471A1 (en) 2013-04-18

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