CN103212085A - 用于使化合物靶向多种选定器官或组织的分子 - Google Patents
用于使化合物靶向多种选定器官或组织的分子 Download PDFInfo
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| CN110997007A (zh) * | 2017-06-28 | 2020-04-10 | 苏图拉医疗有限公司 | 用于改进药物递送的包含钉合肽或拼接肽的化合物 |
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| SI2049664T1 (sl) | 2006-08-11 | 2012-04-30 | Prosensa Technologies Bv | Enojna veriga oligonukleotidov, komplementarna repetitivnim elementom, za zdravljenje genetskih bolezni, povezanih z nestabilnostjo dnk ponovitev |
| ES2639852T3 (es) | 2007-10-26 | 2017-10-30 | Academisch Ziekenhuis Leiden | Medios y métodos para contrarrestar los trastornos musculares |
| EP2119783A1 (en) | 2008-05-14 | 2009-11-18 | Prosensa Technologies B.V. | Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means |
| EP2421971B1 (en) | 2009-04-24 | 2016-07-06 | BioMarin Technologies B.V. | Oligonucleotide comprising an inosine for treating dmd |
| CN102048694B (zh) * | 2009-11-06 | 2013-03-13 | 复旦大学 | 一种多肽修饰的肝肿瘤靶向纳米给药系统及其制备方法 |
| AU2012246822B2 (en) * | 2011-04-22 | 2017-05-25 | Biomarin Technologies B.V. | New compounds for treating, delaying and/or preventing a human genetic disorder such as myotonic dystrophy type 1 (DM1) |
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| NZ627896A (en) | 2012-01-27 | 2016-11-25 | Biomarin Technologies B V | Rna modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy |
| LT2841578T (lt) | 2012-04-23 | 2017-09-25 | Biomarin Technologies B.V. | Rnr moduliuojantys oligonukleotidai su pagerintomis savybėmis, skirti neuromuskulinių susirgimų gydymui |
| HK1210192A1 (en) | 2012-07-19 | 2016-04-15 | Alethia Biotherapeutics Inc. | Anti-siglec-15 antibodies |
| CN103705465B (zh) * | 2012-10-09 | 2016-01-13 | 复旦大学 | 一种微酸环境靶向多肽修饰的肿瘤靶向纳米给药系统及其制备方法 |
| AU2015204452A1 (en) * | 2014-01-13 | 2016-08-11 | Berg Llc | Enolase 1 (Eno1) compositions and uses thereof |
| CN107073065B (zh) * | 2014-08-22 | 2021-07-02 | 密歇根大学董事会 | 用于发育异常、早期癌症和癌症的检测和靶向的肽试剂和方法 |
| CN104800858B (zh) * | 2015-04-27 | 2017-11-21 | 中国医学科学院基础医学研究所 | Hsp90抑制肽偶联物及其在肿瘤治疗中的应用 |
| US11369569B2 (en) | 2015-06-15 | 2022-06-28 | University Of Virginia Patent Foundation | Target-specific delivery of therapeutic agents |
| EP3322405A4 (en) * | 2015-07-16 | 2019-01-23 | Berg LLC | ENOLASE 1 (ENO1) COMPOSITIONS AND USES THEREOF |
| WO2017120504A1 (en) | 2016-01-08 | 2017-07-13 | Durfee Paul N | Osteotropic nanoparticles for prevention or treatment of bone metastases |
| WO2017136435A1 (en) | 2016-02-01 | 2017-08-10 | The Usa, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer National Institute Of Health | Compounds for modulating fc-epsilon-ri-beta expression and uses thereof |
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| WO2009008727A3 (en) | 2009-08-13 |
| CA2942716A1 (en) | 2009-01-15 |
| WO2009008727A2 (en) | 2009-01-15 |
| US20100184948A1 (en) | 2010-07-22 |
| CY1117713T1 (el) | 2017-05-17 |
| AU2008273096B2 (en) | 2013-05-02 |
| CN101815535A (zh) | 2010-08-25 |
| EP2505211A1 (en) | 2012-10-03 |
| EP2167136A2 (en) | 2010-03-31 |
| EP2505211B1 (en) | 2020-04-08 |
| HK1145635A1 (en) | 2011-04-29 |
| DK2167136T3 (en) | 2016-07-25 |
| US8519097B2 (en) | 2013-08-27 |
| IL220979A0 (en) | 2012-08-30 |
| IL203273A (en) | 2014-04-30 |
| CA2942716C (en) | 2019-07-09 |
| CA2693048C (en) | 2016-10-18 |
| CN101815535B (zh) | 2013-04-24 |
| AU2008273096A1 (en) | 2009-01-15 |
| JP2010533171A (ja) | 2010-10-21 |
| US8268962B2 (en) | 2012-09-18 |
| JP5706157B2 (ja) | 2015-04-22 |
| NZ582521A (en) | 2011-09-30 |
| US20120322724A1 (en) | 2012-12-20 |
| CA2693048A1 (en) | 2009-01-15 |
| EP2167136B1 (en) | 2016-04-20 |
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