CN103212010A - Traditional Chinese medicine composition for treating impotence and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating impotence and preparation method thereof Download PDF

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CN103212010A
CN103212010A CN2013101157049A CN201310115704A CN103212010A CN 103212010 A CN103212010 A CN 103212010A CN 2013101157049 A CN2013101157049 A CN 2013101157049A CN 201310115704 A CN201310115704 A CN 201310115704A CN 103212010 A CN103212010 A CN 103212010A
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medicine composition
fructus
draconis
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叶立新
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Abstract

The invention discloses a traditional Chinese medicine composition for treating impotence and a preparation method thereof. The traditional Chinese medicine composition disclosed by the invention comprises the following ingredients in parts by weight: 30-60 parts of bitter cardamon, 30-60 parts of flemingia macrophylla, 30-60 parts of raspberry, 20-50 parts of mistletoe, 20-50 parts of achyranthes root and 10-20 parts of dragon bone. The traditional Chinese medicine composition disclosed by the invention can be prepared into any clinically-acceptable oral pharmaceutical preparation according to conventional traditional Chinese medicine preparation methods. The traditional Chinese medicine composition disclosed by the invention has the effects of invigorating the spleen, benefiting the liver and kidney, stopping emission and invigorating yang; and shown by clinical treatment effects, the traditional Chinese medicine composition disclosed by the invention has definite and reliable treatment effects on impotence, treats both symptoms and root causes, is safe in clinical application and is free of any toxic and side effect.

Description

Chinese medicine composition of treatment sexual impotence and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of sexual impotence and preparation method thereof, belong to the treatment by Chinese herbs field of sexual impotence.
Background technology
Sexual impotence is one of common andropathy, and sickness rate is higher, the cause of disease is complicated, present younger trend.Traditional Chinese medical science traditional theory thinks that the cause of disease, pathogenesis, the method for treatment of sexual impotence relate to liver, kidney, bright three warps of sun more, blame in kidney especially.The cause of disease is summarised as four kinds: decline of the fire from the gate of life, damp and hot flourishing, melancholy burnt labor, suddenly frightened, and in treatment, advocate that warming and recuperating the gate of life, liver heat removing let out fire etc.The gate of vitality refers to the vitals kidney of human body, kidney controlling essence storage, and the treatment sexual impotence, the kidney invigorating is particularly important.Impotence not only influences love life, also can cause male infertility sterile, needs treatment as early as possible.
Summary of the invention
Technical problem to be solved by this invention be overcome the medicine of existing treatment sexual impotence existing take effect slow, curative effect inadequately significantly, defective such as toxic and side effects is big, the Chinese medicine composition of the treatment sexual impotence that provide a kind of instant effect, determined curative effect, has no side effect;
Another technical problem to be solved by this invention provides a kind of method for preparing above-mentioned Chinese medicine composition.
Above-mentioned technical problem to be solved by this invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of sexual impotence comprises following each component: Fructus Alpiniae Oxyphyllae, flemingia macrophylla pull out, Fructus Rubi, Os Draconis, Radix Achyranthis Bidentatae, Herba Taxilli.
Preferably, the weight portion of each component is: Fructus Alpiniae Oxyphyllae 30-60 part, flemingia macrophylla pull out 30-60 part, Fructus Rubi 30-60 part, Herba Taxilli 20-50 part, Radix Achyranthis Bidentatae 20-50 part, Os Draconis 10-20 part.
Preferred, the weight portion of each component is: Fructus Alpiniae Oxyphyllae 30-45 part, flemingia macrophylla pull out 30-45 part, Fructus Rubi 30-45 part, Herba Taxilli 20-35 part, Radix Achyranthis Bidentatae 20-35 part, Os Draconis 10-15 part.
Most preferred, the weight portion of each component is: 40 parts of Fructus Alpiniae Oxyphyllae, flemingia macrophylla pull out 40 parts, 40 parts of Fructus Rubies, 25 parts of Herba Taxillis, 25 parts of Radix Achyranthis Bidentataes, 12 parts of Os Draconis.
Fructus Alpiniae Oxyphyllae: be the fruit of zingiberaceous plant Fructus Alpiniae Oxyphyllae.Nature and flavor: hot, warm.Return spleen channel, kidney channel.Function: warming the spleen, warming the kidney, solid and gas, arresting seminal emission.Cure mainly: cold air stomachache, invasion by pathogenic cold is vomited and diarrhoea, many salivas, seminal emission, dribbling urination, urinate night more.
Radix Flemingiae Macrophyllae: the root that pulls out for the leguminous plant flemingia macrophylla.Nature and flavor: warm, sweet.Function: wind-damp dispelling, the network of invigorating blood circulation, bone and muscle strengthening.Cure mainly: rheumatic ostalgia, lumbar muscle strain, hemiplegia, sexual impotence.
Fructus Rubi: for rosaceous plant Fructus Rubi, rubus coreanus etc. is mature fruit.Nature and flavor: sweet acid, return Liver Channel, kidney channel.Function: invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs makes eye bright.Cure mainly: sexual impotence, seminal emission, incontinence of urine, asthenia, order is dark etc.
Herba Taxilli: be the branch and leaf of Loranthaceae plant Mongolian oak, Herba Taxilli or loranthus yadoriki.Nature and flavor: bitter sweet, flat.Return Liver Channel, kidney channel.Function: invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, the meridian dredging, beneficial blood, antiabortive.Cure mainly: soreness of waist and knee joint, hemiplegia a little less than the muscles and bones flaccidity, beriberi, wind and cold arthralgia pain, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.
Radix Achyranthis Bidentatae: be the root of amaranthaceous plant Radix Achyranthis Bidentatae.Nature and flavor: sweetness and bitterness acid, flat.Return Liver Channel, kidney channel.Function cures mainly: give birth to and use dissipating blood stasis blood, subduing inflammation.Control gonorrhea, hematuria, amenorrhea , mass in the abdomen, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury.Ripely use invigorating the liver and kidney, bone and muscle strengthening.Control soreness of waist and knee joint, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.
Os Draconis: for ancient times mammal as if the fossil of the skeleton of class, rhinoceros class, Hippocampal cortex etc.Main calcium carbonate (the CaCO that contains 3), calcium phosphate (Ca 3(PO 4) 2).Nature and flavor: sweet puckery, flat.GUIXIN, liver, kidney, large intestine channel.Function: tranquillizing the mind by relieving convulsion, hold back Chinese controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control demented, alarmed and panicky forgetful, insomnia and dreamful sleep, spontaneous sweating, the seminal emission stranguria with turbid discharge, bleeding not during menses, dysentery proctoptosis, ulcer do not close up etc. for a long time.
Chinese medicine composition of the present invention is based on the inventor to pathogenetic research of the deep layer of sexual impotence and Therapeutic Principle thereof, simultaneously according to inventor clinical experience and pharmaceutical research achievement for many years, filter out the crude drug of spleen invigorating, liver and kidney tonifying, nocturnal control and yang nourishing, form according to certain weight proportion prescription.
Has better therapeutic efficiency for sexual impotence when further adding the raw material of following weight portion in the present invention in the drug composition: Semen Euryales 8-15 part, Rhizoma Dioscoreae 8-15 part, Herba Ecliptae 6-12 part, Semen Canavaliae 4-10 part; Preferably, the consumption of each component is: 10 parts of Semen Euryaless, 10 parts of Rhizoma Dioscoreaes, 8 parts of Herba Ecliptaes, 6 parts of Semen Canavaliaes.
Semen Euryales: be the mature seed kernel of nymphaeaceae plant Semen Euryales.Nature and flavor: sweet puckery, flat.Return spleen channel, kidney channel.Function: reinforcing the kindey to control nocturnal emission, spleen reinforcing stopping leak.Cure mainly: seminal emission, nebulousurine, stranguria with turbid discharge, leukorrhagia, incontinence of urine, loose stool and diarrhea.
Rhizoma Dioscoreae: be the tuber of Dioscoreaceae plant Rhizoma Dioscoreae.Nature and flavor: sweet, flat.Return: lung meridian, spleen channel, kidney channel.Function: spleen invigorating, tonifying the lung, controlling nocturnal emission with astringent drugs, kidney tonifying.Cure mainly: diarrhea due to hypofunction of the spleen, chronic dysentery, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, frequent micturition.
Herba Ecliptae: be the herb of feverfew Eclipta prostrata.Nature and flavor: sweet acid, cold.Return Liver Channel, kidney channel.Function: removing heat from blood, hemostasis, the kidney invigorating, tonifying YIN.Cure mainly: spit blood, spitting of blood, epistaxis is had blood in stool, dysentery, knife injury is hemorrhage, early whitening of beard and hair, diphtheria, stranguria with turbid discharge, leukorrhagia etc.
Semen Canavaliae: be the seed of leguminous plant Semen Canavaliae.Nature and flavor: sweet, warm.Function: warming the middle warmer and descending qi, kidney tonifying complement.Cure mainly the deficiency and coldness singultus, vomiting, abdominal distention, lumbago due to renal deficiency, phlegm dyspnea.
Each medicine compatibility is played the effect of spleen invigorating, liver and kidney tonifying, nocturnal control and yang nourishing together altogether among the side of the present invention, and Chinese medicine composition of the present invention is for the sexual impotence treating both the principal and secondary aspects of a disease, and clinical observation on the therapeutic effect confirms that Chinese medicine composition of the present invention is reliable, true for the sexual impotence determined curative effect.Chinese medicine composition of the present invention is nontoxic, and is safe and reliable, has no adverse reaction after taking, clinical safe in utilization.
The crude drug of respectively distinguishing the flavor of that the present invention is used can be bought at pharmacy and obtain.
Medicine activity component of the present invention can add various adjuvants required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc., method of Chinese medicinal with routine is prepared into any suitable clinical oral administration preparation, and described oral formulations can be pill, powder, granule, capsule, tablet, oral liquid, drop pill etc.
A kind of preparation method of Chinese medicine composition of the present invention: after each crude drug of the present invention taken by weighing by described weight portion proportioning, pulverize, sieve (for example can be the 100-400 mesh sieve), promptly.Certainly, after also each crude drug can being pulverized, add required adjuvant or the excipient of preparations shaping, be prepared into capsule, tablet or pill according to conventional method.
The another kind of preparation method of Chinese medicine composition of the present invention: take by weighing each crude drug by described weight portion; Each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds the adjuvant or the excipient of preparations shaping, preparations shaping, promptly.
The usage of Chinese medicine composition of the present invention and consumption: dosage of the present invention depends on factors such as concrete dosage form, patient's age, health status.As guidance: usage and dosage: capsule, each capsule content 1.0 gram crude drug, each oral 1 to 3,2 times on the one, 20 days is a course of treatment.
The specific embodiment
Further describe the present invention below in conjunction with specific embodiment; these embodiment only are exemplary; what those skilled in the art should understand that is; down can make amendment or replace without departing from the spirit and scope of the present invention, but these modifications and replacing all fall within the scope of protection of the present invention the details of technical solution of the present invention and form.
The preparation of embodiment 1 capsule
(unit: g): Fructus Alpiniae Oxyphyllae 30, flemingia macrophylla pull out 30, Fructus Rubi 30, Herba Taxilli 20, Radix Achyranthis Bidentatae 20, Os Draconis 10 to take by weighing each crude drug by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add ethanol and make granule in right amount, drying, granulate, filled capsules, promptly.
The preparation of embodiment 2 capsules
(unit: g): Fructus Alpiniae Oxyphyllae 60, flemingia macrophylla pull out 60, Fructus Rubi 60, Herba Taxilli 50, Radix Achyranthis Bidentatae 50, Os Draconis 20 to take by weighing each crude drug by following weight; Above-mentioned each crude drug is decocted with water secondary, add 6 times of weight of water for the first time, decocted 2 hours, add 4 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add ethanol and make granule in right amount, drying, granulate, filled capsules, promptly.
The preparation of embodiment 3 capsules
(unit: g): Fructus Alpiniae Oxyphyllae 40, flemingia macrophylla pull out 40, Fructus Rubi 40, Herba Taxilli 25, Radix Achyranthis Bidentatae 25, Os Draconis 12 to take by weighing each crude drug by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.30-1.35 (55 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add ethanol and make granule in right amount, drying, granulate, filled capsules, promptly.
The preparation of embodiment 4 capsules
(unit: g): Fructus Alpiniae Oxyphyllae 30, flemingia macrophylla pull out 30, Fructus Rubi 30, Herba Taxilli 20, Radix Achyranthis Bidentatae 20, Os Draconis 10, Semen Euryales 8, Rhizoma Dioscoreae 8, Herba Ecliptae 6, Semen Canavaliae 4 to take by weighing each crude drug by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add ethanol and make granule in right amount, drying, granulate, filled capsules, promptly.
The preparation of embodiment 5 capsules
(unit: g): Fructus Alpiniae Oxyphyllae 60, flemingia macrophylla pull out 60, Fructus Rubi 60, Herba Taxilli 50, Radix Achyranthis Bidentatae 50, Os Draconis 20, Semen Euryales 15, Rhizoma Dioscoreae 15, Herba Ecliptae 12, Semen Canavaliae 10 to take by weighing each crude drug by following weight; Above-mentioned each crude drug is decocted with water secondary, add 6 times of weight of water for the first time, decocted 2 hours, add 4 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add ethanol and make granule in right amount, drying, granulate, filled capsules, promptly.
The preparation of embodiment 6 capsules
(unit: g): Fructus Alpiniae Oxyphyllae 40, flemingia macrophylla pull out 40, Fructus Rubi 40, Herba Taxilli 25, Radix Achyranthis Bidentatae 25, Os Draconis 12, Semen Euryales 10, Rhizoma Dioscoreae 10, Herba Ecliptae 8, Semen Canavaliae 6 to take by weighing each crude drug by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.30-1.35 (55 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add ethanol and make granule in right amount, drying, granulate, filled capsules, promptly.
The clinical observation on the therapeutic effect test of test example 1 traditional Chinese medicine composition for treating sexual impotence of the present invention
One, physical data
140 routine patients all meet the clinical diagnosis standard of sexual impotence, 22 years old~58 years old age.The patient is divided into two groups at random, every group 70 example; Difference does not have significance on two groups of ages, courses of disease and the degree that is in a bad way.
Two, trial drug
Embodiment of the invention 1-6 drug prepared.
Three, Therapeutic Method
140 routine patients are divided into 2 groups at random, that is: test 2 groups of 1 group and tests, every group of each 70 example are tested 1 group and are adopted the prepared capsule treatment of embodiment 1-3, test 2 groups and adopt the prepared capsules treatment of embodiment 4-6; Oral, one time 3 (1g crude drug/grain), 2 times on the one, 20 days is a course of treatment, treats 2 courses of treatment altogether; Period in a medicine is withdrawn the treatment of other related drugs and is avoided sexual life.
Four, efficacy assessment standard
Produce effects: transference cure, can normally carry out sexual life; Effectively: symptom obviously alleviates or sx, lifts and not hard but have sometimes.Invalid: the symptom no change.
Five, clinical observation result
Clinical observation result sees Table 1.
The clinical observation on the therapeutic effect result of the test of table 1 traditional Chinese medicine composition for treating sexual impotence of the present invention
Figure BSA00000874761800061
Clinical observation on the therapeutic effect is the result show, Chinese medicine composition of the present invention has significant curative effect for impotence patient; Safety observe to be found, does not observe any clinical adverse, show Chinese medicine composition clinical practice of the present invention safely, have no side effect.

Claims (8)

1. Chinese medicine composition for the treatment of sexual impotence comprises that following each component forms: Fructus Alpiniae Oxyphyllae, flemingia macrophylla pull out, Fructus Rubi, Os Draconis, Radix Achyranthis Bidentatae and Herba Taxilli.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that the weight portion of each component is: Fructus Alpiniae Oxyphyllae 30-60 part, flemingia macrophylla pull out 30-60 part, Fructus Rubi 30-60 part, Herba Taxilli 20-50 part, Radix Achyranthis Bidentatae 20-50 part, Os Draconis 10-20 part.
3. according to the described Chinese medicine composition of claim 2, it is characterized in that the weight portion of each component is: Fructus Alpiniae Oxyphyllae 30-45 part, flemingia macrophylla pull out 30-45 part, Fructus Rubi 30-45 part, Herba Taxilli 20-35 part, Radix Achyranthis Bidentatae 20-35 part, Os Draconis 10-15 part.
4. according to the described Chinese medicine composition of claim 3, it is characterized in that the weight portion of each component is: 40 parts of Fructus Alpiniae Oxyphyllae, flemingia macrophylla pull out 40 parts, 40 parts of Fructus Rubies, 25 parts of Herba Taxillis, 25 parts of Radix Achyranthis Bidentataes, 12 parts of Os Draconis.
5. Chinese medicine composition for the treatment of sexual impotence, comprise that each component of following weight portion is formed: Fructus Alpiniae Oxyphyllae 30-60 part, flemingia macrophylla pull out 30-60 part, Fructus Rubi 30-60 part, Herba Taxilli 20-50 part, Radix Achyranthis Bidentatae 20-50 part, Os Draconis 10-20 part, Semen Euryales 8-15 part, Rhizoma Dioscoreae 8-15 part, Herba Ecliptae 6-12 part, Semen Canavaliae 4-10 part.
6. according to the described Chinese medicine composition of claim 5, it is characterized in that the weight portion of each component is: 40 parts of Fructus Alpiniae Oxyphyllae, flemingia macrophylla pull out 40 parts, 40 parts of Fructus Rubies, 25 parts of Herba Taxillis, 25 parts of Radix Achyranthis Bidentataes, 12 parts of Os Draconis, 10 parts of Semen Euryaless, 10 parts of Rhizoma Dioscoreaes, 8 parts of Herba Ecliptaes, 6 parts of Semen Canavaliaes.
7. method for preparing any one described Chinese medicine composition of claim 1-6 may further comprise the steps:
(1), takes by weighing each crude drug by described weight proportion;
(2), each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds the adjuvant or the excipient of preparations shaping, preparations shaping, promptly.
8. any one described Chinese medicine composition of claim 1-6 is preparing the purposes for the treatment of in the sexual impotence medicine.
CN2013101157049A 2013-03-28 2013-03-28 Traditional Chinese medicine composition for treating impotence and preparation method thereof Pending CN103212010A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758361A (en) * 2015-04-09 2015-07-08 李健 Traditional Chinese medicine preparation for preventing and treating erectile dysfunction and preparation method of traditional Chinese medicine preparation
CN109395003A (en) * 2018-12-29 2019-03-01 广西中医药大学 A kind of Externally-applied Zhuang medicine composition for treating impotence and strong drug paste application and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758361A (en) * 2015-04-09 2015-07-08 李健 Traditional Chinese medicine preparation for preventing and treating erectile dysfunction and preparation method of traditional Chinese medicine preparation
CN109395003A (en) * 2018-12-29 2019-03-01 广西中医药大学 A kind of Externally-applied Zhuang medicine composition for treating impotence and strong drug paste application and preparation method thereof
CN109395003B (en) * 2018-12-29 2021-06-11 广西中医药大学 External Zhuang medicine composition and Zhuang medicine patch application for treating impotence and preparation method thereof

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Application publication date: 20130724