CN109395003A - A kind of Externally-applied Zhuang medicine composition for treating impotence and strong drug paste application and preparation method thereof - Google Patents
A kind of Externally-applied Zhuang medicine composition for treating impotence and strong drug paste application and preparation method thereof Download PDFInfo
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- CN109395003A CN109395003A CN201811632639.6A CN201811632639A CN109395003A CN 109395003 A CN109395003 A CN 109395003A CN 201811632639 A CN201811632639 A CN 201811632639A CN 109395003 A CN109395003 A CN 109395003A
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- 229940079593 drug Drugs 0.000 title claims abstract description 83
- 201000001881 impotence Diseases 0.000 title claims abstract description 54
- 239000000203 mixture Substances 0.000 title claims abstract description 43
- 238000002360 preparation method Methods 0.000 title claims description 14
- 241000395033 Kaempferia Species 0.000 claims abstract description 45
- 235000013422 Kaempferia rotunda Nutrition 0.000 claims abstract description 45
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 37
- 239000000843 powder Substances 0.000 claims abstract description 34
- 241000037488 Coccoloba pubescens Species 0.000 claims abstract description 16
- 241000234276 Curculigo Species 0.000 claims abstract description 16
- 244000285094 Flemingia macrophylla Species 0.000 claims abstract description 16
- 239000002994 raw material Substances 0.000 claims abstract description 16
- 241000146384 Glaux Species 0.000 claims abstract description 13
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- 239000000463 material Substances 0.000 claims description 3
- 238000005728 strengthening Methods 0.000 claims description 3
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- 244000189548 Chrysanthemum x morifolium Species 0.000 claims 1
- 238000011282 treatment Methods 0.000 abstract description 21
- 230000000694 effects Effects 0.000 abstract description 15
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- 208000024891 symptom Diseases 0.000 abstract description 5
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Abstract
The present invention provides a kind of Externally-applied Zhuang medicine compositions for treating impotence, belong to impotence treatment technical field, and the strong drug composition includes following raw material: traditional Chinese medicine powder and kaempferia galamga juice；The traditional Chinese medicine powder includes the raw material of following parts by weight: 0.5~2 part of Flemingia macrophylla, 0.5~2 part of largeleaf curculigo rhizome, 1~3 part of thizoma curculiginis, 1~3 part of cortex cinnamomi and 0.5~2 part of false-yellowflower milkwort root or herb；The kaempferia galamga juice is squeezed the juice as raw material using 1~3 part of kaempferia galamga and is obtained.The all medicines of strong drug composition of the invention are used in combination, and the qi-restoratives that can detoxify, invigorates the kidney and stops nocturnal emission at dredging the channel, achieve the purpose that treat impotence.By clinical verification, the strong drug paste application that strong drug composition of the invention is prepared can be obviously improved impotence patient erection and owe hard symptom, and compared with oral tadalafil tablet, the better extended treatment effect of energy, after January of being discontinued, the erection hardness of Most patients is still ensured that.
Description
Technical field
The present invention relates to impotence treatment technical field more particularly to a kind of Externally-applied Zhuang medicine compositions and strong medicine for treating impotence
Stick agent and preparation method thereof.
Background technique
Impotence, also known as muscle impotence, impotence are equivalent to the erectile dysfunction (Erectile of western medicine
Dysfunction, ED).With the aggravation of population in the world Aging Problem, impotence disease incidence is showed an increasing trend year by year, at present
Few to effective treatment method of impotence patient functional rehabilitation, means are more single, are to cause impotence patient treatment difficult maximum
Deficiency, therefore be current hot and difficult issue to the study on prevention of impotence.
It is more to cause the cause of disease that impotence occurs, mainly includes psychological, organic, mixed type three classes.It is psychological to be mainly
Due to a lack of or acceptance error sex education, by mental wound, the influence of the mental diseases such as anxiety-depression, conjugal relation is uncoordinated
Deng generation；Organic is mainly because of penile disease, the lesion of local vascular, nerve, other systemic diseases etc. generate；Mixed type
Mainly generated because of psychological and organic collective effect.Current most of impotence patients are Combination, and treat impotence
Means it is more single, be broadly divided into oral drugs and two kinds of operative treatment.The drugs such as oral 5 type phosphodiesterase inhibitors exist
It can promote telotism in short time, but the duration is short, side effect is larger, the complication such as dizziness, painful swelling of joints easily occurs, suffers from
Person easily generates dependence to drug.Though the operative treatments such as penile prosthesis implantation can continue improve patient symptom, limitation compared with
Greatly, it is only applicable to irreversible Physical ED patient, and is spent larger.
Summary of the invention
The purpose of the present invention is to provide a kind of Externally-applied Zhuang medicine composition for treating impotence and strong drug paste application and its preparations
Method, the strong drug composition can play the double action of drug absorption and acupoint stimulation, have good impotence treatment effect.
In order to achieve the above-mentioned object of the invention, the present invention the following technical schemes are provided:
The present invention provides a kind of Externally-applied Zhuang medicine compositions for treating impotence, including following raw material: traditional Chinese medicine powder and kaempferia galamga juice；
The traditional Chinese medicine powder includes the raw material of following parts by weight: 0.5~2 part of Flemingia macrophylla, 0.5~2 part of largeleaf curculigo rhizome, thizoma curculiginis 1~3
Part, 1~3 part of cortex cinnamomi and 0.5~2 part of false-yellowflower milkwort root or herb；The kaempferia galamga juice is squeezed the juice as raw material using 1~3 part of kaempferia galamga and is obtained.
Preferably, the traditional Chinese medicine powder includes the raw material of following parts by weight: 1~1.5 part of Flemingia macrophylla, largeleaf curculigo rhizome 1~
1.5 parts, 1.5~2.5 parts of thizoma curculiginis, 1.5~2.5 parts of cortex cinnamomi and 1~1.5 part of false-yellowflower milkwort root or herb.
Preferably, the granularity of the traditional Chinese medicine powder is 18~35 mesh.
Preferably, the water content of the kaempferia galamga is 85%~95%.
The present invention provides the preparation methods that drug composition is strengthened described in above scheme, comprising the following steps:
1) Flemingia macrophylla, largeleaf curculigo rhizome, thizoma curculiginis, cortex cinnamomi and false-yellowflower milkwort root or herb are mixed, crushes, obtains traditional Chinese medicine powder；
2) it squeezes the juice to kaempferia galamga, sterilizes, obtain kaempferia galamga juice；
3) the step 1) traditional Chinese medicine powder and step 2) the kaempferia galamga juice are mixed, obtains strong drug composition；
It is limited between the step 1) and step 2) without sequence.
Preferably, the temperature of the step 2) sterilization is 95~105 DEG C；The time of the sterilization is 8~12min.
The present invention provides a kind of strong drug paste application for treating impotence, and the strong drug paste application includes described in above scheme
Strong drug composition and gauze.
The present invention provides the preparation methods that drug paste application is strengthened described in above scheme, and steps are as follows: combining the strong medicine
Object is applied on gauze, obtains strong drug paste application.
Preferably, the smearing thickness of the strong drug composition is 2~3mm.
Preferably, the size of the gauze is 13~17cm × 13~17cm.
Beneficial effects of the present invention: the present invention provides a kind of Externally-applied Zhuang medicine compositions for treating impotence, including following original
Material: traditional Chinese medicine powder and kaempferia galamga juice；The traditional Chinese medicine powder includes the raw material of following parts by weight: 0.5~2 part of Flemingia macrophylla, largeleaf curculigo rhizome
0.5~2 part, 1~3 part of thizoma curculiginis, 1~3 part of cortex cinnamomi and 0.5~2 part of false-yellowflower milkwort root or herb；The kaempferia galamga juice is original with 1~3 part of kaempferia galamga
Material juicing obtains.The present invention presses its performance, effect according to the combination principle of strong medical knowledge opinion " Your Majesty side draw ", we, be divided into main ingredient,
Public medicine, side medicine, four class of priming.Main ingredient has been the drug of main efficacy results, the monarch drug in a prescription and ministerial drug being equivalent in traditional Chinese medicine；Public medicine
Refer to that nature and flavor are warmmer, to treat a kind of medicine based on asthenia cold syndrome；Side medicine is the drug for assisting main ingredient to generate therapeutic efficiency, is equivalent to
Ministerial drug or adjutant in traditional Chinese medicine；Priming is to play coordinating the drug actions of a prescription, inducting the medicines into affected channel, and being equivalent in traditional Chinese medicine makes medicine.This
In invention, the Flemingia macrophylla can play impotence caused by kidney yang virtual loss and greatly facilitate as main ingredient, energy warming kidney and enhancing yang
Effect is the most important medicine simply of we；The largeleaf curculigo rhizome is equally used as main ingredient, has the function of qi-restoratives astringent method, to kidney qi
Virtual loss or the unconsolidation of the kidney-qi and the impotence that causes has improvement result；The thizoma curculiginis alleviates kidney as public medicine, energy replenishing essence, beneficial marrow, promoting blood circulation
Erection pain, painful ejaculation, improve impotence caused by the empty, stasis of blood caused by insufficiency of essence or stagnation of blood stasis；The cortex cinnamomi is as public medicine, property
Heat, energy warming meridian, guiding fire to origin can preferably improve erection hardness for the impotence of Yang-function insufficiency of kidneyzang type, and when prolonged erection
Between；The false-yellowflower milkwort root or herb has effects that QI invigorating, promoting blood circulation, analgesic as side medicine, can improve to erect caused by deficiency of kidney-QI and owe
Heavily fortified point, or it is hard after it is easily soft, while waist can also be improved and the complication such as ached；The kaempferia galamga juice is as priming, warming middle-Jiao and tonifying deficiency, treatment one
Asthenia cold syndrome is cut, and is mixed into paste as solvent and remaining medicine, forms external patch application.The all medicine connection of strong drug composition of the invention
It closes and uses, the qi-restoratives that can detoxify, invigorates the kidney and stops nocturnal emission at dredging the channel, achievees the purpose that treat impotence.By clinical verification, the present invention
The strong drug paste application that is prepared of strong drug composition can be obviously improved impotence patient and erect the symptom for owing hard.And use this hair
Bright strong drug paste application carries out application treatment compared with oral tadalafil tablet, the better extended treatment effect of energy, in January of being discontinued
Afterwards, the erection hardness of Most patients is still ensured that.
Specific embodiment
The present invention provides a kind of Externally-applied Zhuang medicine compositions for treating impotence, including following raw material: traditional Chinese medicine powder and kaempferia galamga juice；
The granularity of the traditional Chinese medicine powder is preferably 18~35 mesh, more preferably 20~30 mesh, most preferably 25 mesh.Traditional Chinese medicine powder is arranged in the present invention
Granularity be 18~35 purposes the reason is that, the traditional Chinese medicine powder of above-mentioned granularity can be formed when kaempferia galamga juice is added and is mixed to be compared
Good paste can persistently be attached to patient's waist when carrying out application treatment to patient.If particle is too big, cannot be formed steady
Fixed paste；And particle is too small then can cost of idleness.
In the present invention, the strong drug composition includes kaempferia galamga juice；The kaempferia galamga juice is squeezed the juice as raw material using kaempferia galamga and is obtained；It is described
The parts by weight of kaempferia galamga are 1~3 part, more preferably 1.5~2.5 parts；The kaempferia galamga is preferably fresh kaempferia galamga；The kaempferia galamga it is aqueous
Amount preferably 85%~95%, more preferably 90%；The kaempferia galamga acrid flavour, it is warm-natured, it is drawing for strong drug composition of the present invention
Medicine, energy qi-restoratives treat all asthenia cold syndromes, and the kaempferia galamga is mixed into stable paste as solvent and traditional Chinese medicine powder, and composition external application sticks
Agent；The kaempferia galamga is preferably provided by Guangxi University of Chinese Medicine's the first affiliated hospital central pharmacy.
In the present invention, the traditional Chinese medicine powder includes the raw material of following parts by weight: 0.5~2 part of Flemingia macrophylla, largeleaf curculigo rhizome
0.5~2 part, 1~3 part of thizoma curculiginis, 1~3 part of cortex cinnamomi and 0.5~2 part of false-yellowflower milkwort root or herb；The raw material of the traditional Chinese medicine powder is preferably by wide
Western university of TCM's the first affiliated hospital central pharmacy provides.
In the present invention, the traditional Chinese medicine powder includes 0.5~2 part of Flemingia macrophylla, preferably 1~1.5 part；The flemingia macrophylla
Pulling out property sweet, warm, as the main ingredient of strong drug composition of the present invention, energy warming kidney and enhancing yang can send out impotence caused by kidney yang virtual loss
The effect of greatly facilitating is waved, is the most important medicine simply of we.
In the present invention, the traditional Chinese medicine powder includes 0.5~2 part of largeleaf curculigo rhizome, preferably 1~1.5 part；The largeleaf curculigo rhizome taste
Hardship, it is warm-natured, it is equally used as main ingredient, has the function of qi-restoratives astringent method, the impotence caused to kidney qi virtual loss or the unconsolidation of the kidney-qi, which has, to be changed
Kind effect.
In the present invention, the traditional Chinese medicine powder includes 1~3 part of thizoma curculiginis, preferably 1.5~2.5 parts；The bitter of the thizoma curculiginis, property
Temperature is the public medicine of strong drug composition of the present invention, and energy replenishing essence, beneficial marrow, promoting blood circulation are alleviated kidney essence deficiency or stagnation of blood stasis and caused
Erection pain, painful ejaculation, improve impotence caused by the empty, stasis of blood.
In the present invention, the traditional Chinese medicine powder includes 1~3 part of cortex cinnamomi, preferably 1.5~2.5 parts；The cortex cinnamomi is pungent sweet, property heat,
It is the public medicine of strong drug composition of the present invention, energy warming meridian, guiding fire to origin can be preferably for the impotence of Yang-function insufficiency of kidneyzang type
Raising erection hardness, and prolonged erection time.
In the present invention, the traditional Chinese medicine powder includes 0.5~2 part of false-yellowflower milkwort root or herb, preferably 1~1.5 part；The chrysanthemum pours
Lotus is sweet in flavor, slight bitter, mild-natured, is the side medicine of strong drug composition of the present invention, can invigorate blood circulation, relieve pain, and improves caused by deficiency of kidney-QI
Erect and owe heavily fortified point, or it is hard after it is easily soft, while waist can also be improved and the complication such as ached.
Strong drug composition of the invention realizes that all medicines are used in combination, and the qi-restoratives that can detoxify, invigorates the kidney and stops nocturnal emission at dredging the channel, reaches
To the purpose for the treatment of impotence.
The present invention provides the preparation methods that drug composition is strengthened described in above scheme, comprising the following steps:
1) Flemingia macrophylla, largeleaf curculigo rhizome, thizoma curculiginis, cortex cinnamomi and false-yellowflower milkwort root or herb are mixed, crushes, obtains traditional Chinese medicine powder；
2) it squeezes the juice to kaempferia galamga, sterilizes, obtain kaempferia galamga juice；
3) the step 1) traditional Chinese medicine powder and step 2) the kaempferia galamga juice are mixed, obtains strong drug composition；
It is limited between the step 1) and step 2) without sequence.
In the present invention, Flemingia macrophylla, largeleaf curculigo rhizome, thizoma curculiginis, cortex cinnamomi and false-yellowflower milkwort root or herb are mixed, crushes, obtains
Traditional Chinese medicine powder；The time of the crushing is preferably 10~60s, more preferably 30s；The present invention is not special to the temperature of the crushing
Limitation；The equipment of the crushing is preferably medicinal herb grinder, more preferably the bright medicinal herb grinder of the rising sun, specification HK-02A.
In the present invention, it squeezes the juice to kaempferia galamga, sterilizes, obtain kaempferia galamga juice；The present invention does not have the temperature of the juicing
It is specifically limited；The time of the juicing is preferably 10~20min, more preferably 15min；The equipment of the juicing is preferably squeezed the juice
Machine, more preferably other board juice extractor, specification HS-220H；The temperature of the sterilization is preferably 95~105 DEG C, more preferably
100℃；The time of the sterilization is preferably 8~12min, more preferably 10min.
The present invention mixes the traditional Chinese medicine powder and the kaempferia galamga juice after obtaining traditional Chinese medicine powder and kaempferia galamga juice, obtains strong medicine group
Close object；The present invention is not particularly limited the mixed time, mode, temperature；The temperature of kaempferia galamga juice is preferred when the mixing
It is 40~50 DEG C, more preferably 45 DEG C.The temperature of kaempferia galamga juice is conducive to strong medicine combination for 40~50 DEG C when mixing is arranged in the present invention
Object forms stable paste and will not influence drug effect, in addition, 40~50 DEG C of condition can make patient feel comfortable.
The present invention provides a kind of strong drug paste application for treating impotence, and the strong drug paste application includes described in above scheme
Strong drug composition and gauze.
The present invention also provides the application methods that drug paste application is strengthened described in above scheme, and steps are as follows: by the strong medicine group
It closes object to be applied on gauze, obtains strong drug paste application；The smearing thickness of the strong drug composition is 2~3mm；The gauze it is big
Small is 13~17cm × 13~17cm；The number of plies of the gauze is preferably 1~2 layer；The gauze is preferably medical absorbent cotton/gauze.
The present invention provides the application method for strengthening drug paste application described in above scheme, the strong drug paste application is preferably current
Now make；The strong drug paste application is preferably pasted on the waist of patient, more preferably in the 1st spinous process of lumbar vertebra to the 5th spinous process of lumbar vertebra
Entire waist is sticked；The number that sticks of every dose of strong drug paste application is preferably 1 time；Each application time is preferably 20~
50min, more preferably 30~40min.
In the present invention, the strong drug paste application can stimulate the urinary bladder channel of foot-Taiyang, positioned at the Sanjiaoshu of waist, shen shu, big
The gate of vitality in waist of intestines acupoint and governor vessel, Yaoyangkuan(Du 3).
A kind of Externally-applied Zhuang medicine composition for treating impotence and strong drug paste are provided to provided by the invention below with reference to embodiment
Application and preparation method thereof is described in detail, but they cannot be interpreted as limiting the scope of the present invention.
A kind of Externally-applied Zhuang medicine composition for treating impotence of embodiment 1
1. raw material: in parts by weight, Flemingia macrophylla 100g, largeleaf curculigo rhizome 100g, thizoma curculiginis 200g, cortex cinnamomi 200g, chrysanthemum
Omei meadowrue herb 100g, fresh kaempferia galamga 200g (water content 90%), the above Chinese medicine is by the first affiliated hospital, Guangxi University of Chinese Medicine center
Pharmacy provides.
2. preparation method
1) Flemingia macrophylla, largeleaf curculigo rhizome, thizoma curculiginis, cortex cinnamomi, false-yellowflower milkwort root or herb are through the rising sun bright medicinal herb grinder (model: HK-
It 02A) crushes respectively about half a minute, granularity is 20 mesh；
2) at juice after other board juice extractor (model: HS-220H) grinds 15min, juicing is boiled with soft fire fresh kaempferia galamga
10min disinfection and sterilization, then room temperature uses after being cooled to 45 DEG C；
3) it takes 30g traditional Chinese medicine powder and 15g kaempferia galamga juice to be uniformly mixed, obtains strong drug composition.
A kind of strong drug paste application for treating impotence of embodiment 2
Drug composition will be strengthened described in embodiment 1 to be uniformly applied on 1 layer of gauze that specification is 15cm × 15cm, is smeared thick
Degree is 3mm, the strong drug paste application for the impotence that obtains medical treatment.
Embodiment 3 verifies the therapeutic effect of the strong drug paste application of embodiment 2
It goes to a doctor in andrology, the first affiliated hospital, Guangxi University of Chinese Medicine, sentences by international index of erectile function table (IIEF-5)
It is set to 8 points~11 points moderate impotence patients totally 50.It is randomly divided into and sticks group and Tadalafei group, every group of 25 people.
Case selection
Selection meets in the erectile dysfunction guide diagnostic criteria of European Urology Association (EAU) publication in 2017
Spend impotence patient.Exclusion criteria: Diagnosis of Erectile Dysfunction standard person is not 1. met；2. merge intentionally, liver, kidney and hematopoiesis system
It unites, the serious conditions persons such as disorderly system is immunized；3. the major diseases patient such as tumour；4. loner, or it is associated with spirit, neuropathy
It can not the person of cooperation；5. to this drug allergy person；6. once treating in the recent period using similar drugs, related or phase antagonism was such as taken
Drug, cause curative effect of medication to be difficult to judge；7. it is all not by regulation medication, it can not judge that curative effect or data be not congruent and affect the treatment
Or safety judgement person.
Therapeutic scheme
It sticks the strong medicine waist of group use to stick, uses drug to strengthen drug paste application described in embodiment 2.Daily waist, which sticks, to be controlled
Treat 30min, continuous 1 month.
Tadalafei group takes orally tadalafil tablet, and Lilly Co., Eli. produces, import drugs registration certificate number: H30130361,
Specification: 5mg/14 piece/box.The next day sleep at night before 30min it is oral, continuous 1 month.
Observation index
Curative effect determinate standard:
Patient is determined to integrate the range of evaluation according to international index of erectile function table and (is shown in Table 1).Score is inscribed by 5
It is added, it is no impotence that integral, which is greater than 22 points, and 12~21 points are slight impotence, and 8~11 points are moderate impotence, and 5 points~7 points are severe
Impotence.Record is after treatment in 1 month, all each limit of integration number situations of patient.
1 international index of erectile function table (IIEF-5) of table
As a result
After treatment 1 month, records all patients and integrate number situation (being shown in Table 2).Two groups through examining, result difference is without system
Meter learns meaning (P > 0.05), illustrates that two groups of patients after treatment in 1 month, can reach identical effect, can significantly improve
Impotence patient, which erects, owes the symptom of heavily fortified point.
2 two groups of patient's post treatment integral number situations of table
After being discontinued 1 month, record patient integrates number situation (being shown in Table 3).Two groups through examining, result difference has statistics meaning
Adopted (P < 0.05) illustrates two groups of patients after being discontinued 1 month, and application treatment can preferably prolong compared with oral tadalafil tablet
Long therapeutic effect still ensures that the erection hardness of Most patients after January of being discontinued.
Patient integrates number after table 3 is discontinued 1 month
As seen from the above embodiment, the present invention provides a kind of strong drug paste application for treating impotence, the strong drug paste application
It can be obviously improved impotence patient erection and owe hard symptom, and can better extended treatment effect.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications are also answered
It is considered as protection scope of the present invention.
Claims (10)
1. a kind of Externally-applied Zhuang medicine composition for treating impotence, including following raw material: traditional Chinese medicine powder and kaempferia galamga juice；
The traditional Chinese medicine powder includes the raw material of following parts by weight: 0.5~2 part of Flemingia macrophylla, 0.5~2 part of largeleaf curculigo rhizome, thizoma curculiginis 1
~3 parts, 1~3 part of cortex cinnamomi and 0.5~2 part of false-yellowflower milkwort root or herb；
The kaempferia galamga juice is squeezed the juice as raw material using 1~3 part of kaempferia galamga and is obtained.
2. strong drug composition according to claim 1, which is characterized in that the traditional Chinese medicine powder includes the original of following parts by weight
Material: 1~1.5 part of Flemingia macrophylla, 1~1.5 part of largeleaf curculigo rhizome, 1.5~2.5 parts of thizoma curculiginis, 1.5~2.5 parts of cortex cinnamomi and chrysanthemum fall
1~1.5 part of water lotus.
3. strong drug composition according to claim 1 or 2, which is characterized in that the granularity of the traditional Chinese medicine powder is 18~35 mesh.
4. strong drug composition according to claim 1, which is characterized in that the water content of the kaempferia galamga is 85%~95%.
5. strengthening the preparation method of drug composition described in Claims 1 to 4 any one, comprising the following steps:
1) Flemingia macrophylla, largeleaf curculigo rhizome, thizoma curculiginis, cortex cinnamomi and false-yellowflower milkwort root or herb are mixed, crushes, obtains traditional Chinese medicine powder；
2) it squeezes the juice to kaempferia galamga, sterilizes, obtain kaempferia galamga juice；
3) the step 1) traditional Chinese medicine powder and step 2) the kaempferia galamga juice are mixed, obtains strong drug composition；
It is limited between the step 1) and step 2) without sequence.
6. preparation method according to claim 5, which is characterized in that the temperature of the step 2) sterilization is 95~105 DEG C；
The time of the sterilization is 8~12min.
7. a kind of strong drug paste application for treating impotence, which is characterized in that the strong drug paste application includes that Claims 1 to 4 is any
Strong drug composition and gauze described in one.
8. strengthening the preparation method of drug paste application described in claim 7, steps are as follows: will strengthen described in Claims 1 to 4 any one
Drug composition is applied on gauze, obtains strong drug paste application.
9. preparation method according to claim 8, which is characterized in that the smearing thickness of the strong drug composition be 2~
3mm。
10. preparation method according to claim 8 or claim 9, which is characterized in that the size of the gauze is 13~17cm × 13
~17cm.
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| CN101919941A (en) * | 2009-03-18 | 2010-12-22 | 皇甫予苏 | External traditional Chinese medicine composition used for renal function curing and health care and application thereof in preparing traditional Chinese medicine cataplasma for renal function curing and health care |
| CN103212010A (en) * | 2013-03-28 | 2013-07-24 | 叶立新 | Traditional Chinese medicine composition for treating impotence and preparation method thereof |
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