CN103201611B - 用于流动型颗粒分析仪的双反馈真空流动技术 - Google Patents

用于流动型颗粒分析仪的双反馈真空流动技术 Download PDF

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Publication number
CN103201611B
CN103201611B CN201180052384.6A CN201180052384A CN103201611B CN 103201611 B CN103201611 B CN 103201611B CN 201180052384 A CN201180052384 A CN 201180052384A CN 103201611 B CN103201611 B CN 103201611B
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flow
fluid
sample
resistance
pressure drop
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CN103201611A (zh
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D·弗兰
P·O·诺顿
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Becton Dickinson and Co
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N15/1409—Handling samples, e.g. injecting samples
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y10T137/0324—With control of flow by a condition or characteristic of a fluid
    • Y10T137/0379—By fluid pressure

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Optical Measuring Cells (AREA)
  • Fluid Mechanics (AREA)
  • Engineering & Computer Science (AREA)
  • Automation & Control Theory (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CN201180052384.6A 2010-10-29 2011-10-24 用于流动型颗粒分析仪的双反馈真空流动技术 Active CN103201611B (zh)

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Application Number Priority Date Filing Date Title
US40799010P 2010-10-29 2010-10-29
US61/407,990 2010-10-29
PCT/US2011/057445 WO2012058142A1 (en) 2010-10-29 2011-10-24 Dual feedback vacuum fluidics for a flow-type particle analyzer

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CN103201611A CN103201611A (zh) 2013-07-10
CN103201611B true CN103201611B (zh) 2015-03-11

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EP (1) EP2633283B1 (cg-RX-API-DMAC7.html)
JP (1) JP5771696B2 (cg-RX-API-DMAC7.html)
CN (1) CN103201611B (cg-RX-API-DMAC7.html)
AU (1) AU2011320713B2 (cg-RX-API-DMAC7.html)
ES (1) ES2732355T3 (cg-RX-API-DMAC7.html)
SG (1) SG189532A1 (cg-RX-API-DMAC7.html)
WO (1) WO2012058142A1 (cg-RX-API-DMAC7.html)
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Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG149889A1 (en) * 2003-10-30 2009-02-27 Cytonome Inc Multilayer hydrodynamic sheath flow structure
EP2449359B1 (en) * 2009-07-02 2020-01-01 The Governors of the University of Alberta Particle classifier
EP2545357B1 (en) * 2010-03-10 2021-06-02 Beckman Coulter, Inc. Generating pulse parameters in a particle analyzer
EP2926114A4 (en) * 2012-11-29 2016-07-27 Cytoflow Llc FLUIDIC SYSTEM AND METHOD
CN105283753B (zh) 2013-03-14 2020-07-10 塞通诺米/St有限责任公司 流体动力聚焦设备和方法
CN109100288A (zh) 2013-03-15 2018-12-28 艾瑞思国际股份有限公司 用于血液样品中的粒子分析的鞘流体系统和方法
US9372143B2 (en) * 2013-05-15 2016-06-21 Captl Llc Scanning image flow cytometer
US20150107711A1 (en) * 2013-10-21 2015-04-23 Cytoflow, Llc Cytometer flowcell
CN103837462B (zh) * 2014-03-03 2016-10-05 中国科学院苏州生物医学工程技术研究所 一种小型流式细胞仪液路系统
JP5873126B2 (ja) * 2014-04-04 2016-03-01 日本電信電話株式会社 送液方法および送液システム
US20170248511A1 (en) 2014-12-04 2017-08-31 Becton, Dickinson And Company Flow Cytometry Cell Sorting Systems and Methods of Using the Same
CN208443705U (zh) 2014-12-10 2019-01-29 贝克顿·迪金森公司 光学对准的集光系统和测量系统
WO2016100954A1 (en) 2014-12-19 2016-06-23 Captl Llc Flow cytometry using hydrodynamically planar flow
ES2987551T3 (es) 2015-02-18 2024-11-15 Becton Dickinson Co Sistemas de detección óptica y métodos de uso de los mismos
ES2965719T3 (es) 2015-06-17 2024-04-16 Becton Dickinson Co Unidad de tapón de dispersión de detector óptico que tiene una barra de dispersión desmontable y métodos para usar la misma
US10036698B2 (en) 2015-06-19 2018-07-31 Captl Llc Time-sequential cytometry
CN108474728B (zh) 2015-10-13 2022-04-26 贝克顿·迪金森公司 多模态荧光成像流式细胞术系统
US20190086319A1 (en) 2016-03-10 2019-03-21 Becton, Dickinson And Company Methods of evaluating a cellular sample for her-2/neu expression and compositions for practicing the same
JP7130562B2 (ja) 2016-03-17 2022-09-05 ベクトン・ディキンソン・アンド・カンパニー ハイスループット蛍光フローサイトメーターを用いる細胞選別
CN109070083A (zh) 2016-04-22 2018-12-21 贝克顿迪金森公司 用于阵列产生的高密度沉积
KR102381176B1 (ko) 2016-05-12 2022-04-01 비디 바이오사이언시스 개선된 이미지 해상도를 갖는 형광 이미징 유세포 분석법
ES2951466T3 (es) 2016-09-13 2023-10-23 Becton Dickinson Co Citómetro de flujo con ecualización óptica
US10732094B2 (en) 2016-10-03 2020-08-04 Becton, Dickinson And Company Methods and systems for determining a drop delay of a flow stream in a flow cytometer
WO2018094301A1 (en) * 2016-11-19 2018-05-24 Cytek Biosciences, Inc. Flow cytometry systems with stepper flow control valve
US10436697B2 (en) * 2016-11-19 2019-10-08 Cytek Biosciences, Inc. Flow cytometery system with fluidics control system
ES2950436T3 (es) 2016-12-14 2023-10-10 Becton Dickinson Co Métodos y composiciones para obtener una valoración de tuberculosis en un sujeto
JP7058662B2 (ja) 2017-02-08 2022-04-22 ベクトン・ディキンソン・アンド・カンパニー 乾燥色素試薬装置、ならびにその製造及び使用方法
WO2018156371A1 (en) 2017-02-27 2018-08-30 Becton, Dickinson And Company Light detection systems and methods for using thereof
US10613020B2 (en) * 2017-08-10 2020-04-07 The Boeing Company Burr detection systems and methods
US10801617B2 (en) 2018-01-05 2020-10-13 Cnh Industrial America Llc Propel system with active pump displacement control for balancing propel pump pressures in agricultural vehicles
CN111758019B (zh) 2018-01-23 2024-06-28 贝克顿·迪金森公司 用于动态光检测遮蔽的系统及其使用方法
CN119220109A (zh) 2018-03-30 2024-12-31 贝克顿·迪金森公司 含侧基发色团的水溶性聚合染料
WO2019209713A1 (en) 2018-04-27 2019-10-31 Becton, Dickinson And Company Collection systems for flow cytometrically sorted samples and methods of using the same
EP3811055A4 (en) 2018-06-19 2022-08-10 Becton, Dickinson and Company VARIABLE MULTIPLEXING SWITCHES FOR SENSOR NETWORKS, SYSTEMS AND METHODS OF USE THEREOF
US11099066B2 (en) 2018-06-28 2021-08-24 Becton, Dickinson And Company Light detection systems having input and output modulators, and methods of use thereof
US20200056979A1 (en) * 2018-08-15 2020-02-20 Becton, Dickinson And Company Flowrate and vacuum controlled fluid management system for a flow type particle analyzer
WO2020047468A1 (en) 2018-08-30 2020-03-05 Becton, Dickinson And Company Characterization and sorting for particle analyzers
CN109357991B (zh) * 2018-09-27 2020-05-26 清华大学 一种免标记原理的质谱流式细胞进样与离子化装置
WO2020091866A1 (en) 2018-10-30 2020-05-07 Becton, Dickinson And Company Particle sorting module with alignment window, systems and methods of use thereof
US11237093B2 (en) * 2018-12-10 2022-02-01 Bio-Rad Laboratories, Inc. External fluidics system for flow cytometer
JP7528087B2 (ja) 2018-12-28 2024-08-05 ベクトン・ディキンソン・アンド・カンパニー サンプルの蛍光物質をスペクトル的に分解する方法及びシステム
EP3921622A4 (en) 2019-02-08 2022-11-09 Becton, Dickinson and Company DECISION MODULES FOR SORTING DROPLET, SYSTEMS AND METHODS OF USE THEREOF
CN119845832A (zh) 2019-03-22 2025-04-18 贝克顿·迪金森公司 使用射频多路复用激发数据对荧光成像进行光谱解混
EP3867627B1 (en) 2019-03-29 2023-10-25 Becton, Dickinson and Company Parameters for use in particle discrimination
JP7312135B2 (ja) * 2019-04-08 2023-07-20 アークレイ株式会社 送液方法及び分析装置
JP7175231B2 (ja) * 2019-04-08 2022-11-18 アークレイ株式会社 検体の分析方法及び検体の分析装置
CN111796111B (zh) * 2019-04-08 2025-11-21 爱科来株式会社 送液方法和分析装置
WO2020231632A1 (en) 2019-05-14 2020-11-19 Becton, Dickinson And Company Phase-calibration for imaging flow cytometry
CN119935851A (zh) 2019-05-30 2025-05-06 贝克顿·迪金森公司 射频复用信号的相位校正
JP7561822B2 (ja) 2019-07-10 2024-10-04 ベクトン・ディキンソン・アンド・カンパニー 細胞選別分類を調整するための再構成可能な集積回路
WO2021055732A1 (en) * 2019-09-20 2021-03-25 Kansas State University Research Foundation Methods and apparatus for contactless orthographic imaging of aerosol particles
CN114667443A (zh) 2019-11-20 2022-06-24 贝克顿·迪金森公司 具有可调灵敏度的光检测模块
WO2021127364A1 (en) 2019-12-20 2021-06-24 Becton, Dickinson And Company Methods for quantitating extra-cellular vesicle surface markers, and compositions for practicing the same
WO2021154579A1 (en) 2020-01-31 2021-08-05 Becton, Dickinson And Company Methods and systems for adjusting a training gate to accommodate flow cytometer data
JP2023513217A (ja) 2020-02-07 2023-03-30 ベクトン・ディキンソン・アンド・カンパニー クラスタ化波長分割光検出システム及びその使用方法
CN115135986A (zh) 2020-02-19 2022-09-30 贝克顿·迪金森公司 频闪激光器激发系统及其使用方法
US11592386B2 (en) 2020-02-26 2023-02-28 Becton, Dickinson And Company Light detection systems having a secondary light scatter detector and methods for using same
EP4111169A4 (en) 2020-02-27 2023-08-09 Becton, Dickinson and Company METHODS FOR IDENTIFYING SATURATED DATA SIGNALS IN CELL SORTING AND RELATED SYSTEMS
EP4121737A4 (en) 2020-03-17 2023-08-09 Becton, Dickinson and Company GAIN ADAPTED AMPLIFIERS FOR LIGHT DETECTION
WO2021211259A1 (en) 2020-04-16 2021-10-21 Becton, Dickinson And Company Systems for light detection array multiplexing and methods for same
EP4143535A4 (en) 2020-04-28 2023-09-13 Becton, Dickinson and Company METHOD FOR SORTING UNIQUE PHENOTYPES AND CORRESPONDING SYSTEMS
US11879827B2 (en) 2020-04-29 2024-01-23 Becton, Dickinson And Company Methods for modulation and synchronous detection in a flow cytometer and systems for same
EP4147028A4 (en) 2020-05-05 2023-11-08 Becton, Dickinson and Company METHODS FOR DETERMINING DETECTOR GAIN IN A FLOW CYTOMETER
JP7661363B2 (ja) 2020-05-06 2025-04-14 ベクトン・ディキンソン・アンド・カンパニー フローサイトメータデータにおけるスピルオーバー拡散を特徴付けるための方法及びシステム
EP4154256A4 (en) 2020-05-18 2023-11-08 Becton, Dickinson and Company RESOLUTION INDICES FOR DETECTING HETEROGENITY IN DATA AND METHODS FOR USE THEREOF
EP4168774A4 (en) 2020-06-19 2023-12-27 Becton, Dickinson and Company FLOW CYTOMETER WITH ADJUSTABLE POSITION OFFSET SORTING DEFLECTION PLATES AND METHOD OF USE THEREOF
WO2021262359A1 (en) 2020-06-24 2021-12-30 Becton, Dickinson And Company Flow cytometric droplet dispensing systems and methods for using the same
EP4610627A1 (en) 2020-06-26 2025-09-03 Becton Dickinson and Company Dual excitation beams for irradiating a sample in a flow stream and methods for using same
US11965813B2 (en) 2020-08-03 2024-04-23 Cytek Biosciences, Inc. Methods and apparatus for central source pressure-based cytometer fluidics system
US12235201B2 (en) 2020-09-22 2025-02-25 Becton, Dickinson And Company Methods for continuous measurement of baseline noise in a flow cytometer and systems for same
JP2023549475A (ja) 2020-10-20 2023-11-27 ベクトン・ディキンソン・アンド・カンパニー 傾斜ビーム成形光学部品を含むフローサイトメータ、及びフローサイトメータを使用する方法
US20220136956A1 (en) 2020-10-30 2022-05-05 Becton, Dickinson And Company Method and systems for characterizing and encoding a light detection system
JP7766690B2 (ja) 2020-11-19 2025-11-10 ベクトン・ディキンソン・アンド・カンパニー 機械学習分析のためのサイトメトリックデータの最適なスケーリング方法及びそのシステム
WO2022155033A1 (en) 2021-01-13 2022-07-21 Becton, Dickinson And Company Flow cytometers including light collection enhancers, and methods of using the same
WO2022159190A1 (en) 2021-01-25 2022-07-28 Becton, Dickinson And Company Method and systems for determing drop delay using scatter signals across spatially separated lasers
CN214895849U (zh) 2021-01-28 2021-11-26 贝克曼库尔特生物科技（苏州）有限公司 气泡检测装置和样本处理仪
CN117098980A (zh) 2021-02-04 2023-11-21 贝克顿·迪金森公司 集成光询问模块及其使用方法
US12285761B2 (en) 2021-02-05 2025-04-29 Cytek Biosciences, Inc. Integrated air filtering and conditioning of droplet chamber in a compact cell sorter
EP4314765A4 (en) 2021-03-24 2024-10-16 Becton, Dickinson and Company Closed-system sorting flow cytometer adapters and methods of use thereof
EP4327070A4 (en) * 2021-04-23 2024-08-14 Becton, Dickinson and Company FLUID MANAGEMENT SYSTEM FOR A FLOW TYPE ANALYZER AND/OR SORTER PARTICLE ANALYZER
CN117642619A (zh) 2021-05-14 2024-03-01 贝克顿·迪金森公司 采用光谱鉴别法检测光的系统及其使用方法
US12135274B2 (en) 2021-08-10 2024-11-05 Becton, Dickinson And Company Outlet fittings for reducing bubbles at the interface with a flow cell, and flow cytometers and methods using the same
US12467845B2 (en) 2021-08-10 2025-11-11 Becton, Dickinson And Company Clamps for operably coupling an optical component to a mounting block, and methods and systems for using the same
EP4406001A4 (en) 2021-09-21 2025-01-01 Becton, Dickinson and Company BASELINE RESTORATION CIRCUIT
IL311201A (en) 2021-11-17 2024-05-01 Becton Dickinson Co Methods for dynamic real-time adjustment of a data acquisition parameter in a flow cytometer
US20230160807A1 (en) 2021-11-24 2023-05-25 Becton, Dickinson And Company Integrated Flow Cytometry Data Quality Control
CN114594040B (zh) * 2022-03-23 2025-01-03 青岛瑞斯凯尔生物科技股份有限公司 一种流式细胞仪及其工作方法
WO2023239566A1 (en) * 2022-06-06 2023-12-14 Becton, Dickinson And Company Fluidic resistance units, as well as flow cytometers and methods involving the same
US20240312191A1 (en) 2023-03-14 2024-09-19 Becton, Dickinson And Company Methods for determining image filters for classifying particles of a sample and systems and methods for using same
US20240344983A1 (en) 2023-03-30 2024-10-17 Becton, Dickinson And Company Methods and systems for visualizing spectral signatures
CN121014085A (zh) 2023-04-13 2025-11-25 贝克顿迪金森公司 分子诊断信号实时分类方法
EP4454548A1 (en) * 2023-04-25 2024-10-30 Koninklijke Philips N.V. Air flow control for hemodynamic measurement cuff
US20240377307A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods and systems for classifying analyte data into clusters
US20240377311A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods for image-based detection and sorting and systems for same
US20240377325A1 (en) 2023-05-09 2024-11-14 Becton, Dickinson And Company Methods for assessing cell mitochondrial morphology and systems for same
US20250085212A1 (en) 2023-09-07 2025-03-13 Becton, Dickinson And Company Integrated Optofluidic Interrogation Modules, Flow Cytometers Including the Same, and Methods of Use Thereof
US20250137905A1 (en) 2023-10-27 2025-05-01 Becton, Dickinson And Company Fluid Supply Systems Having a Flow Control Circuit and Single Fluidic Connection, and Methods of Use Thereof
US20250237657A1 (en) 2024-01-18 2025-07-24 Becton, Dickinson And Company Methods for spectrally resolving fluorophores of a sample by generalized least squares and systems for same
US20250244333A1 (en) 2024-01-31 2025-07-31 Becton, Dickinson And Company Cell viability compensation (cvc) beads for flow cytometry applications and methods of using the same
US20250297940A1 (en) 2024-03-25 2025-09-25 Becton, Dickinson And Company Methods and systems for classifying analyte data
US20250308080A1 (en) 2024-04-02 2025-10-02 Becton, Dickinson And Company Methods for label-free cell sorting and systems for same
US20250314573A1 (en) 2024-04-05 2025-10-09 Becton, Dickinson And Company Gate/population naming in flow cytometry data analysis based on geometry and data distribution
US20250314577A1 (en) 2024-04-09 2025-10-09 Becton, Dickinson And Company Methods for assessing cell nuclei morphology and systems for same
US20250321179A1 (en) 2024-04-10 2025-10-16 Becton, Dickinson And Company Quantitative flow cytometry light scatter detector alignment
US20250341455A1 (en) 2024-05-03 2025-11-06 Becton, Dickinson And Company Flow cells having an optimized flow channel geometry, flow cytometers including the same, and methods of use thereof
US20250369861A1 (en) 2024-05-31 2025-12-04 Becton, Dickinson And Company Methods and systems for singlet discrimination in flow cytometry data and systems for same
US20250377284A1 (en) 2024-06-11 2025-12-11 Becton, Dickinson And Company Flow cells having optimized high voltage electrodes, flow cytometers including the same, and methods of use thereof
US20250382585A1 (en) 2024-06-13 2025-12-18 Nippon Becton Dickinson Company Ltd Tumor and tissue preservation reagent

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1350668A (zh) * 1999-05-26 2002-05-22 赛布尔仪器科技有限责任公司 带有实时流量测量和修正的宽范围气流系统
CN1606721A (zh) * 2001-10-12 2005-04-13 霍里巴斯特克公司 制造和使用质量流量设备的系统和方法
CN101321983A (zh) * 2005-12-07 2008-12-10 雅固拉器械公司 用于射流系统的脉动衰减器
US7776268B2 (en) * 2005-10-13 2010-08-17 Accuri Cytometers, Inc. User interface for a fluidic system of a flow cytometer

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60140139A (ja) * 1983-12-27 1985-07-25 Toa Medical Electronics Co Ltd 粒子計数装置
US5395588A (en) 1992-12-14 1995-03-07 Becton Dickinson And Company Control of flow cytometer having vacuum fluidics
US5915925A (en) 1997-01-07 1999-06-29 North, Jr.; Howard L. Pulseless liquid supply system for flow cytometry
JP3608066B2 (ja) * 1997-01-14 2005-01-05 株式会社日立製作所 粒子分析装置
IL124514A (en) * 1998-05-17 2002-02-10 Davidson Chaim Method and apparatus for magnetically separating selected particles, particularly biological cells
EP1018644A2 (en) * 1999-01-06 2000-07-12 Bayer Corporation Variable rate particle counter and method of use
GB2381589B (en) * 1999-05-26 2003-09-10 Cyber Instr Technology Llc Wide range gas flow system with real time flow measurement and correction
JP2001050887A (ja) * 1999-08-11 2001-02-23 Sysmex Corp 粒子分析装置
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US6382228B1 (en) * 2000-08-02 2002-05-07 Honeywell International Inc. Fluid driving system for flow cytometry
US20020028434A1 (en) * 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
US7479630B2 (en) * 2004-03-25 2009-01-20 Bandura Dmitry R Method and apparatus for flow cytometry linked with elemental analysis
AU2002318269A1 (en) * 2001-07-18 2003-03-03 The Regents Of The University Of Michigan Gas-focusing flow cytometer cell and flow cytometer detection system with waveguide optics
EP1468266A4 (en) * 2002-01-22 2009-03-11 Beckman Coulter Inc ENVIRONMENTALLY COMPLETED SYSTEM FOR A FLOW CYTOMETER
US6694799B2 (en) * 2002-02-22 2004-02-24 Eastern Washington University Method and apparatus for detection of particles
US6825926B2 (en) * 2002-11-19 2004-11-30 International Remote Imaging Systems, Inc. Flow cell for urinalysis diagnostic system and method of making same
KR101135138B1 (ko) * 2003-08-13 2012-04-16 루미넥스 코포레이션 유세포 분석기식 측정 시스템의 하나 이상의 파라미터의제어 방법
SG149889A1 (en) * 2003-10-30 2009-02-27 Cytonome Inc Multilayer hydrodynamic sheath flow structure
JP2008514955A (ja) * 2004-09-28 2008-05-08 シンギュレックス・インコーポレイテッド サンプル分析システムおよび方法
KR100670590B1 (ko) * 2005-10-05 2007-01-17 주식회사 디지탈바이오테크놀러지 확장된 채널을 가진 마이크로칩 및 이를 이용하는 미세입자 분석 장치
US8017402B2 (en) * 2006-03-08 2011-09-13 Accuri Cytometers, Inc. Fluidic system for a flow cytometer
US8303894B2 (en) * 2005-10-13 2012-11-06 Accuri Cytometers, Inc. Detection and fluidic system of a flow cytometer
US8283177B2 (en) * 2006-03-08 2012-10-09 Accuri Cytometers, Inc. Fluidic system with washing capabilities for a flow cytometer
US7780916B2 (en) * 2006-03-08 2010-08-24 Accuri Cytometers, Inc. Flow cytometer system with unclogging feature
US8715573B2 (en) * 2006-10-13 2014-05-06 Accuri Cytometers, Inc. Fluidic system for a flow cytometer with temporal processing
WO2008058217A2 (en) * 2006-11-07 2008-05-15 Accuri Instruments Inc. Flow cell for a flow cytometer system
US7799575B2 (en) * 2006-11-07 2010-09-21 Genetix Limited Flow cytometers
EP2430424B1 (en) * 2009-05-13 2023-04-26 Sartorius BioAnalytical Instruments, Inc. Flow measurement and control for improved quantification of particles in flow cytometry
US20110061471A1 (en) * 2009-06-02 2011-03-17 Rich Collin A System and method of verification of a sample for a flow cytometer
US8507279B2 (en) * 2009-06-02 2013-08-13 Accuri Cytometers, Inc. System and method of verification of a prepared sample for a flow cytometer
US8941062B2 (en) * 2010-11-16 2015-01-27 1087 Systems, Inc. System for identifying and sorting living cells

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1350668A (zh) * 1999-05-26 2002-05-22 赛布尔仪器科技有限责任公司 带有实时流量测量和修正的宽范围气流系统
CN1606721A (zh) * 2001-10-12 2005-04-13 霍里巴斯特克公司 制造和使用质量流量设备的系统和方法
US7776268B2 (en) * 2005-10-13 2010-08-17 Accuri Cytometers, Inc. User interface for a fluidic system of a flow cytometer
CN101321983A (zh) * 2005-12-07 2008-12-10 雅固拉器械公司 用于射流系统的脉动衰减器

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