CN103182018B - Chinese herbal medicine feed additive for treating chicken colibacillosis and chicken salmonellosis - Google Patents
Chinese herbal medicine feed additive for treating chicken colibacillosis and chicken salmonellosis Download PDFInfo
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Abstract
The invention relates to a Chinese herbal medicine feed additive for treating chicken colibacillosis and chicken salmonellosis. The Chinese herbal medicine feed additive is powder prepared by raw materials in parts by weight as follows: 4-6 parts of andrographis paniculata, 4-6 parts of purslane, 3-4 parts of sophora flavescens, 3-4 parts of garlic, 2-4 parts of atractylodes, 2-4 parts of rhizome atractylodis, 1-2 parts of costustoot, 1-2 parts of poria and 1-2 parts of liquorice. The Chinese herbal medicine feed additive is used for treating chicken colibacillosis and chicken salmonellosis, and has the characteristics of high cure rate, good effect, safety, no toxic or side effects and convenience in use.
Description
Technical field
The present invention relates to a kind of Chinese herbal feed additive for the treatment of chicken colibacillosis, salmonella gallinarum disease.
Background technology
Chicken colibacillosis is a kind of common frdquently encountered disease being caused by escherichia coli.Comprising acute sepsis death, subacute perihepatitis, airsacculitis, constrictive pericarditis, and the multiple sick type such as peritonitis, salpingitis, omphalitis, ophthalmia, and also the chicken at various ages all can infect, and larger to poultry husbandry harm; Intensive poultry and scientific management in recent years obtains after basic controlling many epidemic diseases of chicken, chicken colibacillosis has obvious ascendant trend, become one of harm chicken group main bacteria disease, salmonella gallinarum disease comprises by the caused Pullorum Disease of Pullorum Disease salmonella, the avian typhoid that Salmonella gallinarum causes, the caused avian paratyphoid of salmonella that other amphitrichous can move, its symptom is chickling loss of appetite, diarrhoea, even septicemia death, become chicken anemia, death, sometimes diarrhoea, laying rate decline, also very large to the harm of poultry husbandry.At present, treatment chicken colibacillosis, salmonella gallinarum disease are used Antibiotics Western medicine more, although have certain therapeutic effect, shortcoming is that Drug resistance and side effect and drug residue are more serious.That Chinese herbal medicine has is natural, have no side effect,, the feature such as be difficult for develop immunity to drugs residual without chemicals, is more and more applied to the diseases prevention of home poultry raising and cures the disease.Prior art discloses the Chinese herbal medicine for controlling chicken colibacillosis, salmonella gallinarum disease, but its therapeutic effect is poor, and cure rate is low, and the course for the treatment of is long and cost is high.
Summary of the invention
The object of the invention is to for the problems referred to above, a kind of Chinese herbal feed additive that can effectively treat chicken colibacillosis, salmonella gallinarum disease is provided.
Technical scheme of the present invention is: a kind of Chinese herbal feed additive for the treatment of chicken colibacillosis, salmonella gallinarum disease, it is the powder of being made up of the raw material of following weight proportioning: Herba Andrographis 4-6 part, Herba Portulacae 4-6 part, Radix Sophorae Flavescentis 3-4 part, Bulbus Allii 3-4 part, Rhizoma Atractylodis Macrocephalae 2-4 part, Rhizoma Atractylodis 2-4 part, Radix Aucklandiae 1-2 part, Poria 1-2 part, Radix Glycyrrhizae 1-2 part.
Making the preferred feedstock weight proportion that the present invention treats the Chinese herbal feed additive of chicken colibacillosis, salmonella gallinarum disease is: 5 parts of Herba Andrographis, 5 parts of Herba Portulacaes, 3 parts of Radix Sophorae Flavescentiss, 3 parts, Bulbus Allii, 2 parts of the Rhizoma Atractylodis Macrocephalaes, 2 parts of Rhizoma Atractylodis, 2 parts of the Radix Aucklandiae, 2 parts, Poria, 1 part, Radix Glycyrrhizae.
In prescription of the present invention, each component pharmacological effect is:
Herba Andrographis effect: Herba Andrographis has another name called Chun Lianqiuliu, Herba Andrographitis, Radix Gentianae, golden Rhizoma et radix valerianae, Tremella aurantialba Bandoni et Zang hook, India's grass, Herba vallisneriae Spiralis etc.Bitter in the mouth, cold in nature.GUIXIN, lung, large intestine, urinary bladder channel.Leaf containing Diterpenes as andrographolide, dexyandrographolide, neoandrographolide, dexyandrographolide-19-β-D-Glucose glycoside etc., flavonoid, Polyphenols is as caffeic acid, chlorogenic acid and two caffeoyl silicon thujic acid mixture.Root containing flavonoid as andrographin etc., aerial parts containing Diterpenes as andrographolide etc.Andrographolide, neoandrographolide all have the effect that suppresses and delay Diplococcus pneumoniae and the caused fervescence of hemolytic group B streptococcus.The ability that Herba Andrographis water decoction can improve peripheral blood leucocyte in vitro engulfs staphylococcus aureus.Herba Andrographis has heat-clearing and toxic substances removing, effect of removing heat from blood detumescence.For multi-infection disease, comprise trauma infection contamination, acute bacillary dysentery, acute gastroenteritis etc.
Herba Portulacae effect: Herba portulacae another name long life dish, five elements' grass, peaceful and comfortable dish, horse special vegetables, acid rice dish, longevity greens/mustard green etc. are the herb of dicotyledon medicine portulacaceous plant Herba Portulacae.Cold in nature, sour in the mouth.Return large intestine, liver, spleen channel.Herb is containing a large amount of noradrenalins and volume potassium salt potassium nitrate, potassium chloride, potassium sulfate etc.In addition, still containing dihydroxy benzenes ethamine, dihydroxyphenylalanine, malic acid, citric acid, glutamic acid, aspartic acid, alanine and sucrose, glucose, fructose etc.Containing alkaloid, Coumarins, flavonoid, cardiotonic glycoside and anthraquinone glycoside, still containing vitamin A, B1, B2, PP, C, carotene, calcium, phosphorus, iron salt and Saponin, tannin, resin, fat, urea element etc.Aerial parts also contains vitamin E, mucous matter in leaf.The wax of leaf and stem is made up of hydro carbons, esters, acids, alcohols etc.Aminoacid, can vasoconstrictive smooth muscle, and flavone and Saponin can remove free radical and antioxidation; Alkaloid and flavone can be antibacterial.Herba Portulacae has effect of heat-clearing and toxic substances removing.For acute, subacute enteritis, bacillary dysentery etc.
Radix Sophorae Flavescentis effect: Radix Sophorae Flavescentis another name ground Chinese scholartree, white stem ground bone, Albizzia kalkora, wild Chinese scholartree etc.For the dry root of leguminous plant Radix Sophorae Flavescentis.Bitter in the mouth, cold in nature.Return liver, kidney, large intestine, small intestine meridian, heart channel, urinary bladder channel.In root, contain alkaloid as matrine, oxymatrine, N-oxidation sophocarpine, sophoridine, the other matrine of dextrorotation, dextrorotation Iosmatrine.In root, also contain multiple flavone compound alcohol A as new in Radix Sophorae Flavescentis, B, C, D, E, F, G, H, I, J, K, L, M, N, O, Radix Sophorae Flavescentis chalcone derivative, Radix Sophorae Flavescentis chalcone derivative alcohol.In addition, in root, also contain triterpenoid saponin as Radix Sophorae Flavescentis saponin I, II, III, IV, soyasaponins I and quinones.Aerial parts contains alkaloid as matrine, oxymatrine, Iosmatrine, sophoranl, sophoranl N-oxide, anagyrine etc.Radix Sophorae Flavescentis has the effect of anti-inflammation, and staphylococcus aureus, escherichia coli are all had to inhibitory action.Radix Sophorae Flavescentis has effect of heat clearing and damp drying.Cure mainly damp-heat dysentery; Discharging fresh blood stool; Jaundice; The diseases such as edema.
Bulbus Allii effect: Bulbus Allii another name Bulbus Allii, Bulbus Allii, DUSUAN, giant garlic are Liliaceae Allium herbaceos perennial.Acrid in the mouth, temperature.Return spleen, stomach, lung meridian.Active ingredient contains protein, fat, carbohydrate, calcium, phosphorus, ferrum, vitamin C.In addition, also contain the trace element such as thiamine, riboflavin, nicotinic acid, allicin, citral and selenium and germanium.Also, containing volatile oil, in oil, Main Ingredients and Appearance is allicin.Still the sulfide compound forming containing multiple pi-allyl, propyl group and methyl etc.In Bulbus Allii, sulfur-containing compound has strong antibacterial and anti-inflammation functions, and multiple bacillus is had and suppressed and killing action, is the strongest one of antibacterial action in the natural plants of finding at present.Bulbus Allii can be removed the intestines and stomach noxious substance, and stimulating gastrointestinal mucosa promotes appetite, accelerates digestion.Bulbus Allii has effect of detoxicating, killing bacteria, antidiarrheal dysentery relieving.For dysentery have loose bowels, eating accumulation, circulation of qi promoting removing food stagnancy.Also for enteritis, eating accumulation etc.
Rhizoma Atractylodis Macrocephalae effect: Rhizoma Atractylodis Macrocephalae another name Rhizoma Atractylodis Macrocephalae, the winter Rhizoma Atractylodis Macrocephalae, wash rice art, poplar small wooden raft, Wu's art, sheet art, is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.Bitter in the mouth, sweet, temperature.Return spleen, stomach warp.Containing volatile oil, Main Ingredients and Appearance is atractylol, atractylone etc., and contains vitamin A.Still containing atractylodes lactone, β-celery oil alkene, Eucalyptus terpene; Another containing oxygen Coumarins, saccharide and resin etc.The Rhizoma Atractylodis Macrocephalae can strengthen the phagocytic function of reticuloendothelial system, and in the time of leukopenia, the Rhizoma Atractylodis Macrocephalae has effect in increasing leukocyte.The Rhizoma Atractylodis Macrocephalae can also improve lymhocyte transformation rate and natural Flos Rosae Rugosae formation rate, promotes cellular immune function, and obviously increases IgG, and the effect that the Rhizoma Atractylodis Macrocephalae has strengthening the spleen and stomach, strong health and improves resistance against diseases is described.Rhizoma Atractylodis Macrocephalae decoct all has bacteriostasis in various degree to Bacillus typhi, paratyphoid bacillus A, shigella flexneri, escherichia coli etc.The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, effect of dampness diuretic.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Rhizoma Atractylodis effect: Rhizoma Atractylodis are called red art, blue or green art, magic arts is the plant of Compositae [WTBX.Perennial vertical herbage.Property is pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Rhizome is containing volatile oil, include 2-carene, chamigrene, Flos Caryophylli alkene, elemene, Humuleno, selinene, patchoulene, 1,9-Fructus Aristolochiae diene, Kessazulen alcohol, elemol, atractylone, contain again tryptophan, 3,5-dimethoxy-4 '-glucosyloxy phenyl 1-propenol-3 etc.That Rhizoma Atractylodis have is drying damp and strengthening spleen, effect of expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, the edema of having loose bowels, rheumatic arthralgia.Cure mainly the spleen and stomach being stranded by dampness, the diseases such as inappetence.
Radix Aucklandiae effect: Radix Aucklandiae another name honey perfume, Radix Aristolochiae, spices, five Radix Aucklandiae are common names of feverfew Saussurea lappa Clarke and Radix Vladimiriae.Acrid in the mouth, hardship, warm in nature.Return spleen, stomach, liver, lung meridian.Volatile oil is mainly containing dehydrocostuslactone, and costunolide, also contains Radix Aucklandiae terpene aldehyde, 4 'beta '-methoxy dehydrocostuslactone, constuslactone etc., costen, aplotaxene, myrcene, beta-elemene etc., alpha, beta-lonone, linalool, cedar wood alcohol, costol, elemol, Palmic acid and linoleic acid etc.Root also contains aspartic acid, glutamic acid, glycine, citrulline, 20 seed amino acids such as γ-aminobutyric acid, cholamine, Radix Aucklandiae terpene amine A, B, C, D, E etc.Leaf is containing taraxasterol, α-amyrin stearate etc.The pungent temperature of this product is fragrant loose, can rise and can fall, and the especially gas of benefaction gastrointestinal and pain relieving, has the merit of strengthening the spleen to promote digestion concurrently, and all cards are conventional product due to all taste QI stagnation of the large intestine.This savors decoct has inhibitory action to Salmonella paratyphi.The Radix Aucklandiae has effect of intestinal stasis relieving in circulation of qi promoting, tune.Be used for the treatment of born of the same parents and coerce distension, tell and have loose bowels, tenesmus.
Poria effect: Poria is commonly called as Poria, Song Ling, Poria, for colonizing in the fungi plant on pinaster root.Sweet in the mouth is light flat.GUIXIN, lung, spleen channel.Active ingredient has polysaccharide to be mainly pachyman, carboxymethyl pachymose, the not acid of triterpene carboxylic acid pachymic acid, soil, eburicoic acid, loose Siberian cocklebur acid, loose Siberian cocklebur eo-acid etc.In addition, containing histidine, adenine, choline, β-pachyman enzyme, protease, sad, lauric acid, Palmic acid, fat, lecithin, ergosterol, phosphatidylcholine and PHOSPHATIDYL ETHANOLAMINE etc.Poria has effect of eliminating dampness and diuresis, invigorating the spleen and regulating the stomach.For vomiting, malignant histocytosis, the disease such as have loose bowels.
Radix Glycyrrhizae effect: Radix Glycyrrhizae another name Glycyrrhizae, close sweet, close grass, state are old, Herba Hedyotis cantonensis, leather and fur.Property is put down, sweet in the mouth.Return 12 warps.Radix Glycyrrhizae is mainly containing compositions such as glycyrrhizic acids, glycyrrhizin, 24-hydroxyl enoxolone, licoflavone, glycyrrhizin, isoliquiritigenin, Angelica Polysaccharide, has antiulcer, promotes pancreatic secretion, protects the liver, the effect such as the phagocytic function of blood fat reducing, adjusting macrophage.Glycyrrhizic acid is natural antidote, can be used for body defying age, enhancing immunity, maintains water-electrolyte metabolism balance etc.Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, cushion toxicity, strong.
Prescription foundation of the present invention: chicken colibacillosis, salmonella gallinarum disease have become the principal disease of restriction poultry husbandry development, after chicken morbidity, presents septicemia death, or dyspnea, diarrhoea, the symptoms such as row's yellow-white and green feces, egg drop reduction when these symptoms appear in Adult Chicken.Therefore in treatment, should be take anti-inflammation, heat clearing and damp drying, removing pathogenic heat from blood and toxic substance from the body, dysentery relieving as the rule for the treatment of.Herba Andrographis, Herba Portulacae heat-clearing and toxic substances removing in side, cooling blood for hemostasis; The Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Radix Aucklandiae invigorating the spleen and benefiting QI, dampness diuretic, appetite strengthening; Radix Sophorae Flavescentis, Bulbus Allii anti-inflammation, appetite stimulator in addition, accelerates digestion; Poria enhancing human body immunity function, invigorating the spleen and regulating the stomach; The sweet temperature QI invigorating of Radix Glycyrrhizae and middle spleen invigorating, current twelve channels and collaterals, coordinating the actions of various ingredients in a prescription.In side all medicine phases and, play altogether effect of anti-inflammation, heat clearing and damp drying, removing pathogenic heat from blood and toxic substance from the body, dysentery relieving, YIN nourishing and the production of body fluid promoting, be applicable to chicken colibacillosis and salmonella gallinarum disease.For convenience of the application in treatment, make powder.
The present invention treats the Chinese herbal feed additive of chicken colibacillosis and salmonella gallinarum disease, to carry out on the basis of a large amount of practical applications, according to traditional medicine ancient prescription, form in conjunction with sick of modern popular, the theoretical screening of nosetiology, to thering is good therapeutic effect by chicken colibacillosis and salmonella gallinarum disease.
The specific embodiment
The invention will be further described in conjunction with the embodiments.
Embodiment:
1, take respectively raw material (decoction pieces), Herba Andrographis 250 g; Herba Portulacae 250 g; Radix Sophorae Flavescentis 150 g; Bulbus Allii 150 g; The Rhizoma Atractylodis Macrocephalae 100 g; Rhizoma Atractylodis 100 g; The Radix Aucklandiae 100 g; Poria 100 g; Radix Glycyrrhizae 50 g;
2, above-mentioned raw materials is ground into respectively to coarse powder, mixes; Stir evenly, subpackage, makes the present invention and treats the Chinese herbal feed additive of chicken colibacillosis, salmonella gallinarum disease.
Some test situation of utilizing Chinese herbal feed additive of the present invention to carry out are as follows:
1, Chinese herbal feed additive of the present invention is to chicken colibacillosis, salmonella drug sensitive test
Choose clinical trouble chicken colibacillosis, the sick case of salmonella gallinarum, through separating, identifying 2 kinds of pathogen as escherichia coli O78 and Pullorum Disease salmonella.Take a certain amount of Chinese herbal feed additive of the present invention and make liquid, every mL contains crude drug 1g, sterilizing, and subpackage, 4 ℃ save backup.The escherichia coli O78 of clinical separation and Pullorum Disease salmonella are first inoculated in to flat board, after 37 ℃ of cultivation 18 h, select colonies typical and be inoculated in 5 mL meat soups, cultivate after 18 h in 37 ℃, 0.5 Maxwell unit's standard opacity tube is than turbid, bacterium liquid is diluted to 105 CFU/mL with meat soup, for subsequent use.
Medicament sensitivity test: adopt plate punch method, the liquid that adds 1g/mL to be made by Chinese herbal feed additive of the present invention in hole, to fill it up with, overfolw hole is not advisable outward.Choose and generally acknowledged escherichia coli, the good three kinds of antibiotic of salmonella effect are compared as the drug sensitive test of ciprofloxacin (1 μ g/mL), amikacin (1 μ g/mL), gentamycin (1 μ g/mL), be placed in 37 ℃ of constant incubators and cultivate 24 h, measure antibacterial circle diameter, the drug sensitive test of every kind of medicine in triplicate.Criterion: the standard according to " pharmacology of Chinese materia medica " with " Standardization Institute of clinical laboratory of U.S. version in 2005 is about drug sensitive test standardization ", be bacteriostatic diameter >=20 mm for extremely quick, 20 mm> bacteriostatic diameter >=15 mm are Gao Min; 15 mm> bacteriostatic diameter >=10 mm are quick in being, 10 mm are hypoallergenic below.
Chinese herbal feed additive medicament sensitivity test of the present invention the results are shown in Table 1.
The drug sensitive test result mm of table 1 Chinese herbal feed additive of the present invention to two kinds of bacterium
| Medicine | Escherichia coli O78 | Pullorum Disease salmonella |
| Ciprofloxacin | 20.0±1.0 | 20.0±0.5 |
| Amikacin | 19.8±0.5 | 20.0±0.8 |
| Gentamycin | 19.5±0.9 | 19.4±1.0 |
| Chinese herbal feed additive of the present invention | 22.2±1.0 | 21.3±0.6 |
Table 1 shows, to escherichia coli O78, Chinese herbal feed additive of the present invention is for extremely quick, and bacteriostatic diameter reaches 22.2 mm, and ciprofloxacin, amikacin and gentamycin are Gao Min; To Pullorum Disease salmonella, Chinese herbal feed additive of the present invention is for extremely quick, and bacteriostatic diameter reaches 21.3mm, other medicines as ciprofloxacin, amikacin and gentamycin be Gao Min.Drug sensitivity test shows, Chinese herbal feed additive of the present invention is the most responsive to the inhibitory action of escherichia coli O78, and ciprofloxacin takes second place, and amikacin, gentamycin are slightly time; Chinese herbal feed additive of the present invention is the most responsive to the inhibitory action of Pullorum Disease salmonella, and amikacin takes second place, and ciprofloxacin and gentamycin are slightly inferior.Result shows, Chinese herbal medicine of the present invention is raised medicine feed additive should serve as first-selection in treatment chicken colibacillosis, the sick practice of salmonella gallinarum.
2, the clinical trial of artificial challenge's chicken colibacillosis, salmonella gallinarum disease
The clinical trial of artificial challenge's chicken colibacillosis: 180 brown laying hens of 50 age in days Yi Sha are divided into 6 groups at random, 30 every group, grouping and processing method are in table 2.
The grouping of table 2 experimental animal and processing method (unit: only)
Except normal healthy controls group injection sterile saline 1 mL, all the other respectively organize every equal Escherichia Coli Injection liquid of chickling (O78,6 × 108/mL) 1 mL.There is colibacillosis classical symptom in test chicken after counteracting toxic substances 36 h (except normal healthy controls group), starts, by table 1 dosed administration, to be used in conjunction 5 d, observes the clinical change after administration, records clinical symptoms and the death toll of each group of chicken every day.The clinical trial chickling grouping of artificial infection chicken's salmonellosis, injection salmonella gallinarum (6 × 108/mL), administration, observation of symptoms are equal to coli-infection experiment.Experimental result is in table 3 and table 4.
The therapeutic outcome of table 3 chicken colibacillosis Experimental infection (unit: only, %)
The therapeutic outcome of the sick Experimental infection of table 4 salmonella gallinarum (unit: only, %)
From table 3 and table 4, the high, medium and low dosage group of Chinese herbal feed additive of the present invention is compared with infecting matched group, and cure rate inequality heteropole is (P<0.01) significantly; High, the middle dosage group of this feed additive and amikacin comparison, cure rate is significant difference (P<0.05); The cure rate of low dose group not significantly (P>0.05) of difference that compare with amikacin.
3, the clinical trial of natural infection chicken colibacillosis, salmonella gallinarum disease
The adult laying hen of clinical trial natural occurrence of 3.1 natural infection chicken colibacillosis is provided by Changli County, Hebei province, Luan County, Leting County, Lulong County, the each raiser in Funing County respectively, root according to clinical symptoms, cut open that inspection changes, animal inoculation test and laboratory examination results, be finally diagnosed as chicken colibacillosis.Take chicken infected as test group separately, morbidity chicken group is mixed in this Chinese herbal feed additive in feedstuff and feeds by only the grow up dosage of laying hen of 1g/, and every day 2 times, dispensing 5～7d is a course for the treatment of.After drug withdrawal, continue to observe 3～5d, with clinical symptom disappearance, drink water, search for food and the mental status is recovered normal person and is judged to healing, then binding of pathological cuts open inspection and takes a sample test result and determine prevention effect, statistics cure rate.Therapeutic outcome is in table 5.
The therapeutic effect of table 5 Chinese herbal feed additive of the present invention to the sick chicken of natural infection colibacillosis (unit: only, %)
By the treatment of laying hen that 8200 natural infection escherichia coli morbidities are grown up, Chinese herbal feed additive of the present invention has significant therapeutic effect to the colibacillosis of the laying hen that grows up, average cure rate is 96.24%, generally through 5～7d transference cure, recover normally to search for food, laying rate is gone up, and returns to the level of normally laying eggs that approaches through 2～4 weeks.
The clinical trial of 3.2 natural infection salmonella gallinarum diseases
The adult laying hen of natural infection salmonella gallinarum morbidity is provided by Changli County, Hebei province, Luan County, Leting County, Lulong County, the each raiser in Funing County respectively, becomes chicken grouping, administration, observation of symptoms to be equal to chicken colibacillosis experiment.Therapeutic outcome is in table 6.
The therapeutic effect of table 6 Chinese herbal feed additive of the present invention to the sick chicken of natural infection salmonellosis (unit: only, %)
Observe by laying hen treatment that 14100 natural infection salmonella morbidities are grown up, Chinese herbal feed additive of the present invention has significant effect to the treatment of natural infection salmonellosis chicken, average cure rate is 94.1%, generally through the sick chicken rehabilitation of 5～7d, recover normally to search for food, laying rate is gone up, and returns to the level of normally laying eggs of approaching through 2～4 weeks, and dispensing whole process has no chicken group and has any untoward reaction.
Claims (2)
1. treat the Chinese herbal feed additive of chicken colibacillosis, salmonella gallinarum disease for one kind, it is characterized in that it is the powder of being made up of the raw material of following weight proportioning: Herba Andrographis 4-6 part, Herba Portulacae 4-6 part, Radix Sophorae Flavescentis 3-4 part, Bulbus Allii 3-4 part, Rhizoma Atractylodis Macrocephalae 2-4 part, Rhizoma Atractylodis 2-4 part, Radix Aucklandiae 1-2 part, Poria 1-2 part, Radix Glycyrrhizae 1-2 part.
2. the Chinese herbal feed additive for the treatment of chicken colibacillosis according to claim 1, salmonella gallinarum disease, it is characterized in that it is the powder of being made up of the raw material of following weight proportioning: 5 parts of Herba Andrographis, 5 parts of Herba Portulacaes, 3 parts of Radix Sophorae Flavescentiss, 3 parts, Bulbus Allii, 2 parts of the Rhizoma Atractylodis Macrocephalaes, 2 parts of Rhizoma Atractylodis, 2 parts of the Radix Aucklandiae, 2 parts, Poria, 1 part, Radix Glycyrrhizae.
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103933544B (en) * | 2014-04-25 | 2015-11-25 | 广西大学 | A kind of poultry compound medicine containing Herba Andrographis and colistin |
| CN103933543B (en) * | 2014-04-25 | 2015-12-02 | 广西大学 | Utilize the method for Herba Andrographis and colistin treatment poultry coli-infection disease |
| CN106177764A (en) * | 2016-08-11 | 2016-12-07 | 王华伟 | A kind of Chinese medicine treating chicken colibacillosis |
| CN106615942A (en) * | 2016-12-21 | 2017-05-10 | 广西浩昌敏再生资源利用有限公司 | Fodder for preventing and treating chicken colibacillosis and preparation method thereof |
| CN107581392A (en) * | 2017-10-17 | 2018-01-16 | 肖秋花 | It is a kind of to be used to prevent and treat feed addictive of chicken colibacillosis and preparation method thereof |
| CN108371689A (en) * | 2018-03-12 | 2018-08-07 | 河北锦坤动物药业有限公司 | A kind of animal formulation containing allicin |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101537063A (en) * | 2009-04-14 | 2009-09-23 | 马晓海 | Formulation method for treating chicken dysentery and toxic heat |
| CN102293900B (en) * | 2011-09-06 | 2012-09-05 | 郭长义 | Chinese medicine for treating infantile diarrhea |
| CN102671168A (en) * | 2012-05-07 | 2012-09-19 | 成都绿迪科技有限公司 | Traditional Chinese medicine composition for treating bacillary dysentery |
-
2013
- 2013-03-21 CN CN201310091316.1A patent/CN103182018B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101537063A (en) * | 2009-04-14 | 2009-09-23 | 马晓海 | Formulation method for treating chicken dysentery and toxic heat |
| CN102293900B (en) * | 2011-09-06 | 2012-09-05 | 郭长义 | Chinese medicine for treating infantile diarrhea |
| CN102671168A (en) * | 2012-05-07 | 2012-09-19 | 成都绿迪科技有限公司 | Traditional Chinese medicine composition for treating bacillary dysentery |
Non-Patent Citations (2)
| Title |
|---|
| 李树珩等.鸡白痢病的治疗.《当代畜禽养殖业》.1995,(第09期), |
| 鸡白痢病的治疗;李树珩等;《当代畜禽养殖业》;19951231(第09期);11－12 * |
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| CN103182018A (en) | 2013-07-03 |
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