CN103142497B - 一种依托泊苷肠溶颗粒 - Google Patents
一种依托泊苷肠溶颗粒 Download PDFInfo
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- CN103142497B CN103142497B CN201310092498.4A CN201310092498A CN103142497B CN 103142497 B CN103142497 B CN 103142497B CN 201310092498 A CN201310092498 A CN 201310092498A CN 103142497 B CN103142497 B CN 103142497B
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- etoposide
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Description
包合材料 | 溶解速度(min) | 稳定性 | 包合率 |
α-环糊精 | 12 | 一般 | 80% |
β-环糊精 | 14 | 一般 | 82% |
羟基β-环糊精 | 12 | 一般 | 78% |
羟丙基β-环糊精 | 5 | 好 | 93% |
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CN201310092498.4A CN103142497B (zh) | 2013-03-21 | 2013-03-21 | 一种依托泊苷肠溶颗粒 |
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CN201310092498.4A CN103142497B (zh) | 2013-03-21 | 2013-03-21 | 一种依托泊苷肠溶颗粒 |
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CN103142497A CN103142497A (zh) | 2013-06-12 |
CN103142497B true CN103142497B (zh) | 2014-04-30 |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1478481A (zh) * | 2002-12-06 | 2004-03-03 | 重庆华邦制药股份有限公司 | 依托泊甙肠溶缓(控)释固体分散制剂及其制备方法 |
CN101411692A (zh) * | 2008-11-14 | 2009-04-22 | 李铁军 | 一种依托泊苷分散片及其制备方法 |
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- 2013-03-21 CN CN201310092498.4A patent/CN103142497B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1478481A (zh) * | 2002-12-06 | 2004-03-03 | 重庆华邦制药股份有限公司 | 依托泊甙肠溶缓(控)释固体分散制剂及其制备方法 |
CN101411692A (zh) * | 2008-11-14 | 2009-04-22 | 李铁军 | 一种依托泊苷分散片及其制备方法 |
Non-Patent Citations (2)
Title |
---|
中等取代度的羟丙基-β-环糊精对依托泊苷的包埋特性分析;孙鹤文等;《药物分析杂志》;20111231;第31卷(第11期);第2103-2107页 * |
孙鹤文等.中等取代度的羟丙基-β-环糊精对依托泊苷的包埋特性分析.《药物分析杂志》.2011,第31卷(第11期),第2103-2107页. |
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Address after: 266103 Qingdao economic and Technological Development Zone, unity Road, No. 3601, Shandong Applicant after: Qingdao Zhengda Haier Pharmaceutical Co., Ltd. Address before: 266103 Haier Road, Shandong, Qingdao, No. 1 Applicant before: Qingdao Zhengda Haier Pharmaceutical Co., Ltd. |
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Address after: 266103 3601 Tuen Jie Road, Qingdao economic and Technological Development Zone, Shandong Patentee after: Zhengda Pharmaceutical (Qingdao) Co., Ltd. Address before: 266103 3601 Tuen Jie Road, Qingdao economic and Technological Development Zone, Shandong Patentee before: Qingdao Zhengda Haier Pharmaceutical Co., Ltd. |
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CP01 | Change in the name or title of a patent holder |